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| 102 | ADCYAP1R1 | ARP59945_P050 | PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb. J Neurophysiol. 113, 1234-48 (2015). 25475351 | 25475351 |
| 103 | ADGRG1 | ARP58627_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism.iScience104823258August2022 | 35992092 |
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| 107 | ADIPOR2 | ARP60819_P050 | Effects of Obesity on Adiponectin System Skin Expression in Dogs: A Comparative Study. Animals (Basel). 11, NULL (2021) 34438765 | 34438765 |
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| 118 | AGPAT2 | ARP44636_P050 | Fetuin-A modulates lipid mobilization in bovine adipose tissue by enhancing lipogenic activity of adipocytes. J Dairy Sci. 102, 4628-4638 (2019). 30827564 | 30827564 |
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| 121 | AHR | ARP32243_T100 | The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells. Int J Environ Res Public Health. 12, 7506-18 (2015). 26154658 | 26154658 |
| 122 | AHSG | ARP33815_P050 | Gil-Dones, F. et al. Inside human aortic stenosis: a proteomic analysis of plasma. J. Proteomics 75, 1639-53 (2012). 22178735 | 22178735 |
| 123 | AHSG | ARP33815_P050 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 124 | AIF1 | OAGA00004 | Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. Int. J. Dev. Neurosci. 55, 56-65 (2016). 27666383 | 27666383 |
| 125 | AIF1 | OAGA00004 | Histological Changes of the Testicular Interstitium during Postnatal Development in Microminipigs. Toxicol Pathol. 47, 469-482 (2019). 30739565 | 30739565 |
| 126 | AIF1 | OAGA00004 | Spontaneous Age-Related Histopathological Changes in Microminipigs. Toxicol Pathol. 47, 817-832 (2019). 31337280 | 31337280 |
| 127 | AIP1 | ARP61404_P050 | Doukhanine, E., Gavino, C., Haines, J. D., Almazan, G. & Richard, S. The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. Mol. Biol. Cell 21, 3029-40 (2010). 20631256 | 20631256 |
| 128 | AKR1B10 | OAGA00776 | LncRNA 1700020I14Rik promotes AKR1B10 expression and activates Erk pathway to induce hepatocyte damage in alcoholic hepatitis.Cell Death Discov37481August2022 | 36028503 |
| 129 | AKR1C1 | OAGA00409 | Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. Sci Rep. 9, 10457 (2019). 31320667 | 31320667 |
| 130 | AKR1C1 | OAGA00409 | Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity. Front Endocrinol (Lausanne). 11, 599869 (2021). 33584538 | 33584538 |
| 131 | AKT | OAAF00965 | Tsai, T.-C. et al. The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos. J. Biomed. Sci. 19, 63 (2012). 22776023 | 22776023 |
| 132 | AKT1 | AVARP06008_P050 | The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development. NULL, NULL (2020) 33318149 | 33318149 |
| 133 | AKT1 | OAAB09732 | The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development 2020 NULL NULL NULL 34004944 | 34004944 |
| 134 | AKT3 | OAAB16215 | Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation. EMBO Rep. 19, (2018). 29335246 | 29335246 |
| 135 | ALAD | ARP41657_P050 | Iron metabolic pathways in the processes of sponge plasticity. PLoS One. 15, e0228722 (2020). 32084159 | 32084159 |
| 136 | ALB | ARP41746_P050 | Holzer, M. et al. Uremia alters HDL composition and function. J. Am. Soc. Nephrol. 22, 1631-41 (2011). 21804091 | 21804091 |
| 137 | ALCAT1 | ARP44426_P050 | LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1. J. Cell. Sci. 129, 51-64 (2016). 26604221 | 26604221 |
| 138 | ALDOA | ARP48130_T100 | Braceland, M. et al. Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. J. Fish Dis. doi:10.1111/jfd.12296 (2014). 25168106 | 25168106 |
| 139 | ALDOA | ARP48130_T100 | Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish. Mol Biol Evol. 37, 2887-2899 (2020) 32437540 | 32437540 |
| 140 | ALG1 | ARP49252_P050 | Rind, N. et al. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. Hum. Mol. Genet. 19, 1413-24 (2010). 20080937 | 20080937 |
| 141 | ALG11 | ARP44463_P050 | Rind, N. et al. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. Hum. Mol. Genet. 19, 1413-24 (2010). 20080937 | 20080937 |
| 142 | ALG2 | ARP48974_P050 | Rind, N. et al. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. Hum. Mol. Genet. 19, 1413-24 (2010). 20080937 | 20080937 |
| 143 | ALG2 | ARP48974_P050 | Cossins, J. et al. Congenital myasthenic syndromes due to mutations in ALG2 and ALG14. Brain 136, 944-56 (2013). 23404334 | 23404334 |
| 144 | ALG2 | ARP48974_P050 | Novel pathogenic ALG2 mutation causing congenital myasthenic syndrome: A case report. Neuromuscul Disord. (2021). 34980536 | 34980536 |
| 145 | ALKBH1 | OACA06689 | ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease. J Clin Invest. 131, NULL (2021) 34003800 | 34003800 |
| 146 | ALOX15 | ARP56030_P050 | The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir. Res. 16, 147 (2015). 26646719 | 26646719 |
| 147 | ALOX5 | OKEH00967 | ALOX5-5-HETE promotes gastric cancer growth and alleviates chemotherapy toxicity via MEK/ERK activation. Cancer Med 2021 15 10 5246-5255 34121352 | 34121352 |
| 148 | ALPL | OKEH00757 | Effects of the Highly COX-2-Selective Analgesic NSAID Etoricoxib on Human Periodontal Ligament Fibroblasts during Compressive Orthodontic Mechanical Strain. Mediators Inflamm. 2019, 2514956 (2019). 30983880 | 30983880 |
| 149 | ALPL | OKEH00757 | The role of mechanotransduction versus hypoxia during simulated orthodontic compressive strain-an in vitro study of human periodontal ligament fibroblasts. Int J Oral Sci. 11, 33 (2019). 31685804 | 31685804 |
| 150 | AMBN | ARP61489_P050 | Isolation and characterization of embryonic ameloblast lineage cells derived from tooth buds of fetal miniature swine. In Vitro Cell. Dev. Biol. Anim. 52, 445-53 (2016). 26698579 | 26698579 |
| 151 | AMH | ARP54312_P050 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
| 152 | AMH | ARP54312_P050 | Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. J Vet Med Sci. 82, 1113-1117 (2020). 32554955 | 32554955 |
| 153 | AMH | ARP54312_P050 | Bovine gonadotrophs express anti-Müllerian hormone (AMH): comparison of AMH mRNA and protein expression levels between old Holsteins and young and old Japanese Black females. Reprod Fertil Dev. 31, 810-819 (2019) 30554590 | 30554590 |
| 154 | AMH | ARP54312_P050 | Anti-Müllerian hormone and its receptor are detected in most gonadotropin-releasing-hormone cell bodies and fibers in heifer brains. Domest Anim Endocrinol. 72, 106432 (2020) 32169754 | 32169754 |
| 155 | AMH | OAAB06540 | Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family. Proc Natl Acad Sci U S A. 118 (2021) 34155118 | 34155118 |
| 156 | AMH | OKEH00320 | Decrease in ovarian reserve through the inhibition of SIRT1-mediated oxidative phosphorylation. Aging (Albany NY) 2022 5 14 2335-2347 35275845 | 35275845 |
| 157 | AMOT | ARP34660_P050 | VCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions. J Leukoc Biol. 104, 215-228 (2018). 29889984 | 29889984 |
| 158 | AMOT | ARP34661_P050 | Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice. PLoS Biol. 17, e3000253 (2019). 31042703 | 31042703 |
| 159 | AMOTL1 | ARP42927_P050 | Skouloudaki, K. & Walz, G. YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation. PLoS One 7, e35735 (2012). 22558212 | 22558212 |
| 160 | ANGPTL2 | ARP54835_P050 | Doblinger, E. et al. Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II. Am. J. Physiol. Renal Physiol. 302, F1313-24 (2012). 22357923 | 22357923 |
| 161 | ANGPTL2 | OKEH01367 | Urinary Cysteine-Rich Protein 61 and Trefoil Factor 3 as Diagnostic Biomarkers for Colorectal Cancer. Transl Oncol. 12, 539-544 (2019). 30611902 | 30611902 |
| 162 | ANK1 | ARP42566_T100 | Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum. J Cell Sci. 122, 2640-50 (2009). 19584095 | 19584095 |
| 163 | ANK1 | ARP42566_T100 | Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers. J Cell Biol. 194, 105-20 (2011). 21727195 | 21727195 |
| 164 | ANK1 | ARP42566_T100 | Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. Mol Biol Cell. 23, 2490-504 (2012). 22573887 | 22573887 |
| 165 | ANK1 | ARP42566_T100 | Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms. FEBS J. 285, 481-500 (2018). 29265728 | 29265728 |
| 166 | ANKH | OAAB06341 | Szeri, et al. The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP. PLoS Genetics 2020 Jul 8;16(7):e1008884. 32639996 | 32639996 |
| 167 | ANKH | OAAB06341 | The Mineralization Regulator ANKH Mediates Cellular Efflux of ATP, Not Pyrophosphate.J Bone Miner Res1024-1031375May2022 | 35147247 |
| 168 | ANKRD11 | ARP33542_T100 | Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome. Hum Genet 2015 2 134 181-90 25413698 | 25413698 |
| 169 | ANKRD55 | ARP68892_P050 | Novel Insights into the Multiple Sclerosis Risk Gene ANKRD55. J. Immunol. 196, 4553-65 (2016). 27183579 | 27183579 |
| 170 | ANKS6 | OAAB10271 | Mutations in ANKS6 cause a nephronophthisis-like phenotype with ESRD. J Am Soc Nephrol. 25, 1653-61 (2014). 24610927 | 24610927 |
| 171 | ANO1 | OAAB13882 | Yin, L. et al. Glucose stimulates calcium-activated chloride secretion in small intestinal cells. Am. J. Physiol. Cell Physiol. 306, C687-96 (2014). 24477233 | 24477233 |
| 172 | ANO10 | ARP47389_P050 | Anoctamins, a novel family of ion channels and their role in intracellular calcium signaling. Journal of Cell Science. 125, 4991-4998 (2015). 22946059 | 22946059 |
| 173 | ANO10 | ARP47389_P050 | A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity. Mol. Med. 21, 26-37 (2015). 25730773 | 25730773 |
| 174 | ANO10 | ARP47389_P050 | Expression of anoctamins in retinal pigment epithelium (RPE). Pflugers Arch. 468, 1921-1929 (2016). 27822608 | 27822608 |
| 175 | ANO10 | ARP47389_P050 | Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling. Cell. Signal. 30, 41-49 (2017). 27838374 | 27838374 |
| 176 | ANO4 | ARP39173_P050 | Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function. Membranes (Basel) 2022 2 12 NULL 35207044 | 35207044 |
| 177 | ANO6 | ARP44761_P050 | Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages. Nat Commun. 6, 6245 (2015). 25651887 | 25651887 |
| 178 | ANXA1 | ARP36568_T100 | Nordon, I. M. et al. Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms. J. Vasc. Surg. 54, 1100-1108.e6 (2011). 21741794 | 21741794 |
| 179 | ANXA1 | ARP36568_T100 | Ishida, Y. et al. Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel electrophoresis. Hum. Cell 27, 68-77 (2014). 24323765 | 24323765 |
| 180 | ANXA2 | ARP47760_P050 | Annexin A2 binds the internal ribosomal entry site of c-myc mRNA and regulates its translation. RNA Biol 2021 sup1 18 337-354 34346292 | 34346292 |
| 181 | ANXA3 | ARP36578_T100 | Seliger, B. et al. Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics 9, 1567-81 (2009). 19235166 | 19235166 |
| 182 | ANXA3 | ARP36578_T100 | Schordan, S. et al. Alterations of the podocyte proteome in response to high glucose concentrations. Proteomics 9, 4519-28 (2009). 19688724 | 19688724 |
| 183 | ANXA3 | ARP36578_T100 | Bianchi, C. et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am. J. Pathol. 176, 1660-70 (2010). 20167856 | 20167856 |
| 184 | ANXA3 | ARP36578_T100 | Meyer-Schwesinger, C. et al. Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis. J. Immunol. 187, 3218-29 (2011). 21844386 | 21844386 |
| 185 | ANXA4 | ARP36686_T100 | de la Cuesta, F. et al. A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima. Mol. Cell. Proteomics 10, M110.003517 (2011). 21248247 | 21248247 |
| 186 | ANXA4 | ARP36686_T100 | Staquicini, F. I. et al. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc. Natl. Acad. Sci. U. S. A. 108, 18637-42 (2011). 22049339 | 22049339 |
| 187 | AOC1 | ARP41908_P050 | Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease. Sci Adv. 5, eaav0316 (2019). 30906861 | 30906861 |
| 188 | AP3B1 | ARP33647_P050 | LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. Sci Rep. 6, 29945 (2016). 27424887 | 27424887 |
| 189 | APOA5 | OKCD09560 | CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. J Clin Invest. 131 (2021). 34491909 | 34491909 |
| 190 | APOBEC3G | ARP33540_T100 | Chen, H., Wang, L.-W., Huang, Y.-Q. & Gong, Z.-J. Interferon-alpha Induces High Expression of APOBEC3G and STAT-1 in Vitro and in Vivo. Int. J. Mol. Sci. 11, 3501-12 (2010). 20957108 | 20957108 |
| 191 | APOC2 | OKEH05270 | CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. J Clin Invest. 131 (2021). 34491909 | 34491909 |
| 192 | APOE | ARP54283_P050 | Rohn, T. T., Catlin, L. W., Coonse, K. G. & Habig, J. W. Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer’s disease brain. Brain Res. 1475, 106-15 (2012). 22902767 | 22902767 |
| 193 | APOE | ARP54283_P050 | Rohn, T. T., Day, R. J., Sheffield, C. B., Rajic, A. J. & Poon, W. W. Apolipoprotein E pathology in vascular dementia. Int. J. Clin. Exp. Pathol. 7, 938-47 (2014). 24696712 | 24696712 |
| 194 | APOE | ARP54283_P050 | Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain. Aging Dis. 7, 267-77 (2016). 27330841 | 27330841 |
| 195 | APOE | ARP54283_P050 | Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain. Int J Physiol Pathophysiol Pharmacol. 9, 40-57 (2017). 28533891 | 28533891 |
| 196 | APOE | ARP54283_P050 | Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease. J Neurol Neurol Disord. 3, (2017). 29520379 | 29520379 |
| 197 | APOE | OKEH04368 | Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics. J Proteome Res. 19, 1258-1266 (2020). 32037835 | 32037835 |
| 198 | APOE | ARP32714_P050 | Fragmentation of Apolipoprotein E4 is Required for Differential Expression of Inflammation and Activation Related Genes in Microglia Cells. Int J Neurodegener Dis 2021 1 4 NULL 34693295 | 34693295 |
| 199 | APOO | OAAB09635 | Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 3, e1700677 (2017). 28835921 | 28835921 |
| 200 | APOOL | OAAF03292 | QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife. 4, (2015). 25997101 | 25997101 |
| 201 | APOOL | OAAF03292 | QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife. 5, (2016). 27623147 | 27623147 |
| 202 | APOOL | OAAF03292 | Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 3, e1700677 (2017). 28835921 | 28835921 |
| 203 | APP42 | OKEH00815 | Exosomes Derived from Human Amniotic Fluid Mesenchymal Stem Cells Preserve Microglia and Neuron Cells from Aβ.Int J Mol SciNULL239April2022 | 35563358 |
| 204 | APTX | ARP40014_T100 | Dopeso, H. et al. Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment. Clin. Cancer Res. 16, 2375-82 (2010). 20371676 | 20371676 |
| 205 | AQP2 | OKEH03152 | Urinary reabsorption in the rat kidney by anticholinergics. Sci Rep 2021 1 11 9191 33911165 | 33911165 |
| 206 | AQp4 | OACA04834 | Astrogliogenesis in human fetal brain: complex spatiotemporal immunoreactivity patterns of GFAP, S100, AQP4 and YKL-40. J Anat 2019 3 235 590-615 30901080 | 30901080 |
| 207 | AQUAPORIN 4 | OABB01958 | PDGF-B Is Required for Development of the Glymphatic System. Cell Rep. 26, 2955-2969.e3 (2019). 30865886 | 30865886 |
| 208 | AR | OKCD00824 | High-Load Resistance Exercise Augments Androgen Receptor-DNA Binding and Wnt/β-Catenin Signaling without Increases in Serum/Muscle Androgens or Androgen Receptor Content. Nutrients. 12, (2020). 33333818 | 33333818 |
| 209 | Arachidonic acid | OKEH02583 | Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration. Cell Mol Life Sci. 77, 1153-1175 (2020). 31302749 | 31302749 |
| 210 | Arachidonic acid | OKEH02583 | PNPLA3 I148M mediates the regulatory effect of NF-kB on inflammation in PA-treated HepG2 cells. J Cell Mol Med. 24, 1541-1552 (2020). 31793207 | 31793207 |
| 211 | ARACHIDONIC ACID | OKEH02583 | Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells. Toxins (Basel). 12, NULL (2020). 32977607 | 32977607 |
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| 213 | AREB6 | ARP30976_P050 | Kothandaraman, N. et al. E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. BMC Cancer 10, 64 (2010). 20181230 | 20181230 |
| 214 | AREG | OKCD05604 | DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. iScience. 24, 103086 (2021). 34568799 | 34568799 |
| 215 | AREG | OKEH00009 | DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. iScience. 24, 103086 (2021). 34568799 | 34568799 |
| 216 | ARF6 | ARP54598_P050 | Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse. Elife. 5, (2016). 26731518 | 26731518 |
| 217 | ARG1 | ARP45672_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 218 | ARG1 | OAEB02142 | Jäger, K. et al. Enzymes of urea synthesis are expressed at the ocular surface, and decreased urea in the tear fluid is associated with dry-eye syndrome. Graefes Arch. Clin. Exp. Ophthalmol. 251, 1995-2002 (2013). 23740519 | 23740519 |
| 219 | ARG2 | ARP54567_P050 | Lukasova, M., Malaval, C., Gille, A., Kero, J. & Offermanns, S. Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J. Clin. Invest. 121, 1163-73 (2011). 21317532 | 21317532 |
| 220 | Arginine vasopressin | OKEH02585 | Timeline of Changes in Biomarkers Associated with Spinal Cord Injury-Induced Polyuria. Neurotrauma Rep. 2, 462-475 (2021). 34901942 | 34901942 |
| 221 | ARHGDIA | OAAF00618 | α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions. BMC Biol 2021 1 19 130 34158053 | 34158053 |
| 222 | ARHGEF7 | OASG05888 | Platelet-derived growth factor receptor-a and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 313, L1174-L1187 (2017). 28775097 | 28775097 |
| 223 | ARL13B | ARP52779_P050 | Zhang, Z. et al. Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One 6, e24608 (2011). 21935430 | 21935430 |
| 224 | ARNT | ARP30979_P050 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J. Physiol. (Lond.). 26574162 | 26574162 |
| 225 | ARPC2 | ARP58587_P050 | Al Ghouleh, I., Rodríguez, A., Pagano, P. J. & Csányi, G. Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration. Int. J. Mol. Sci. 14, 20220-35 (2013). 24152438 | 24152438 |
| 226 | ARSA | OKEH05888 | Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control. Nat Commun 2022 1 13 1259 35273160 | 35273160 |
| 227 | ARV1 | ARP49756_P050 | Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy. Hum Mol Genet. 25, 3042-3054 (2016). 27270415 | 27270415 |
| 228 | ARX | ARP36824_T100 | Condomines, M. et al. Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma. J. Immunol. 183, 832-40 (2009). 19542363 | 19542363 |
| 229 | ARX | ARP36824_T100 | Price, M. G. et al. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J. Neurosci. 29, 8752-63 (2009). 19587282 | 19587282 |
| 230 | ASAH1 | ARP57760_P050 | Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice. J Proteomics. 145, 237-45 (2016). 27268958 | 27268958 |
| 231 | ASAH1 | ARP57760_P050 | Acid ceramidase is upregulated in AML and represents a novel therapeutic target. Oncotarget. 7, 83208-83222 (2016). 27825124 | 27825124 |
| 232 | ASAH1 | OAPB00726 | Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?. BMJ Open Diabetes Res Care. 8, (2020). 32144130 | 32144130 |
| 233 | ASAHL | ARP44939_P050 | A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells. Biochim. Biophys. Acta. 1861, 1951-1958 (2016). 27693242 | 27693242 |
| 234 | ASCL1 | ARP32355_T100 | Vias, M. et al. Pro-neural transcription factors as cancer markers. BMC Med. Genomics 1, 17 (2008). 18489756 | 18489756 |
| 235 | ASCL1 | ARP32355_T100 | Suozzi, A., Malatesta, M. & Zancanaro, C. Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle. J. Anat. 214, 956-62 (2009). 19538638 | 19538638 |
| 236 | ASCL2 | ARP32025_P050 | Park, J.-I. et al. B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria. Mol. Cell. Endocrinol. 367, 31-40 (2013). 23273993 | 23273993 |
| 237 | ASGP1 | ARP33805_P050 | Chang, T.-C. et al. Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions. Bioconjug. Chem. 24, 1895-906 (2013). 24151840 | 24151840 |
| 238 | ASGP2 | ARP33820_P050 | Chang, T.-C. et al. Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions. Bioconjug. Chem. 24, 1895-906 (2013). 24151840 | 24151840 |
| 239 | ASL | ARP41667_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 240 | ASS1 | ARP41366_T100 | Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. PLoS One. 9, e100077 (2014). 24945279 | 24945279 |
| 241 | ASS1 | ARP41366_T100 | Argininosuccinate neurotoxicity and prevention by creatine in argininosuccinate lyase deficiency: An in vitro study in rat three-dimensional organotypic brain cell cultures. J Inherit Metab Dis. 42, 1077-1087 (2019) 30907007 | 30907007 |
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| 243 | ATF4 | ARP37017_P050 | Methods for monitoring endoplasmic reticulum stress and the unfolded protein response. Int J Cell Biol. 2010, 830307 (2010). 20169136 | 20169136 |
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| 294 | B4GALNT1 | ARP45118_P050 | Diversity of glycosphingolipid GM2 and cholesterol accumulation in NPC1 patient-specific iPSC-derived neurons. Brain Res. 1657, 52-61 (2017). 27923633 | 27923633 |
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| 298 | B-ACTIN | ARP40174_P050 | Regular exercise modulates cardiac mast cell activation in ovariectomized rats. J Physiol Sci. 66, 165-73 (2016). 26467449 | 26467449 |
| 299 | BAD | ARP30278_P050 | Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured buffalo granulosa cells. Theriogenology. 86, 1818-33 (2016). 27374424 | 27374424 |
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| 301 | BAG2 | ARP42177_T100 | BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. Elife. 4, (2015). 26271008 | 26271008 |
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| 324 | BECLIN1 | ARP58874_P050 | Alteration of Phospholipids during the Mitophagic Process in Lung Cancer Cells. J. Microbiol. Biotechnol. 26, 1790-1799 (2016). 27363475 | 27363475 |
| 325 | BEST3 | ARP50108_P050 | Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury. Front Physiol. 10, 23 (2019). 30761013 | 30761013 |
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| 354 | BRD9 | ARP34803_T100 | Middeljans, E. et al. SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexes. PLoS One 7, e33834 (2012). 22442726 | 22442726 |
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| 358 | BTG2 | ARP33561_P050 | BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence. Aging Cell. 9, 747-60 (2010). 20569234 | 20569234 |
| 359 | BTG2 | ARP33561_P050 | Park, J.-I. et al. B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria. Mol. Cell. Endocrinol. 367, 31-40 (2013). 23267836 | 23267836 |
| 360 | BTNL3 | ARP46769_P050 | Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen. Immunity. 51, 813-825.e4 (2019). 31628053 | 31628053 |
| 361 | C14ORF142 | ARP69018_P050 | Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. Nucleic Acids Res. 45, 805-817 (2017). 27903914 | 27903914 |
| 362 | C15orf48 | OABB01958 | Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network. PLoS Biol 2020 12 18 e3001045 33370271 | 33370271 |
| 363 | C16orf80 | ARP34302_P050 | Laligné, C. et al. Bug22p, a conserved centrosomal/ciliary protein also present in higher plants, is required for an effective ciliary stroke in Paramecium. Eukaryot. Cell 9, 645-55 (2010). 20118210 | 20118210 |
| 364 | C1D | ARP50534_P050 | Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nat Commun. 10, 2229 (2019). 31110176 | 31110176 |
| 365 | C1orf151 | ARP44801_P050 | Jans, D. C. et al. STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria. Proc. Natl. Acad. Sci. U. S. A. 110, 8936-41 (2013). 23676277 | 23676277 |
| 366 | C1orf166 | ARP43313_P050 | Hooper, C. L., Paudyal, A., Dash, P. R. & Boateng, S. Y. Modulation of stretch-induced myocyte remodeling and gene expression by nitric oxide: a novel role for lipoma preferred partner in myofibrillogenesis. Am. J. Physiol. Heart Circ. Physiol. 304, H1302-13 (2013). 23504181 | 23504181 |
| 367 | C1ORF61 | ARP34802_P050 | Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 24, 584-594 (2021). 33723434 | 33723434 |
| 368 | C1qB | ARP44297_P050 | Kuramoto, A. et al. The formation of immune complexes is involved in the acute phase of periodontal destruction in rats. J. Periodontal Res. 47, 455-62 (2012). 22283745 | 22283745 |
| 369 | C1qB | ARP44297_P050 | Yoshinaga, Y. et al. Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide. J. Periodontal Res. 47, 674-80 (2012). 22582894 | 22582894 |
| 370 | C1qB | ARP44297_P050 | Nagano, F. et al. Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction. J. Periodontal Res. 48, 420-7 (2013). 23137272 | 23137272 |
| 371 | C1qB | ARP44297_P050 | Nakatsu, S. et al. Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats. J. Periodontal Res. (2013). doi:10.1111/jre.12109 23808820 | 23808820 |
| 372 | C1QB | ARP44297_P050 | Histopathological comparison of the onset of peri-implantitis and periodontitis in rats. Clin Oral Implants Res. 28, 163-170 (2017). 26804139 | 26804139 |
| 373 | C1QB | ARP44297_P050 | The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium. J. Periodont. Res. 52, 74-82 (2017). 26957231 | 26957231 |
| 374 | C21orf13 | ARP45912_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 375 | C21ORF59 | ARP45873_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 376 | C2CD2L | ARP47080_P050 | Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 355, (2017). 28209843 | 28209843 |
| 377 | C2CD2L | ARP47080_P050 | Benjamin D Stein, et al. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. 3331-3348.e7 (2019). 31801093 | 31801093 |
| 378 | C5B-9 | OKCD01373 | Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy. Blood. 134, 1095-1105 (2019). 31409673 | 31409673 |
| 379 | C5B-9 | OKCD01373 | Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis. Transl Psychiatry. 10, 361 (2020). 33106473 | 33106473 |
| 380 | C6orf134 | ARP42641_P050 | Kalebic, N. et al. Tubulin acetyltransferase aTAT1 destabilizes microtubules independently of its acetylation activity. Mol. Cell. Biol. 33, 1114-23 (2013). 23275437 | 23275437 |
| 381 | C6orf150 | ARP52607_P050 | Schoggins, J. W. et al. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472, 481-5 (2011). 21478870 | 21478870 |
| 382 | CA1 | OKEH01283 | Lymphaticovenous Anastomosis Supermicrosurgery Decreases Oxidative Stress and Increases Antioxidant Capacity in the Serum of Lymphedema Patients. J Clin Med. 10 (2021). 33917571 | 33917571 |
| 383 | CACNA2D1 | ARP34952_P050 | Identification of Glycosylation Sites Essential for Surface Expression of the CaVa2d1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity. J. Biol. Chem. 291, 4826-43 (2016). 26742847 | 26742847 |
| 384 | CACNA2D1 | OAEB01261 | Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21357696 | 21357696 |
| 385 | CACNA2D1 | OAEB01261 | Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway. Cardiovasc Res. 101, 288-96 (2014) 24233972 | 24233972 |
| 386 | CACNG4 | OASG04296 | Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis. EBioMedicine. 52, 102646 (2020). 32062352 | 32062352 |
| 387 | CALCA | OKCD00726 | Role of perivascular nerve and sensory neurotransmitter dysfunction in inflammatory bowel disease. Am J Physiol Heart Circ Physiol 2021 5 320 H1887-H1902 33710922 | 33710922 |
| 388 | CALCITRIOL | OKEH02542 | Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish. Proc Natl Acad Sci U S A. 115, 12763-12768 (2018). 30446615 | 30446615 |
| 389 | CALCRL | ARP42260_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism.iScience104823258August2022 | 35992092 |
| 390 | CALR | ARP30114_p050 | MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. Cancer Prev Res (Phila). 26342024 | 26342024 |
| 391 | CAMP | OKEH00728 | Association of vitamin D3, VDR gene polymorphisms, and LL-37 with a clinical form of Chagas Disease. Rev Soc Bras Med Trop. 52, e20190133 (2019). 31508781 | 31508781 |
| 392 | CANX | OKCD00229 | Zhenhua Du, et al. Quantitative proteomics identifies a plasma multi-protein model for detection of hepatocellular carcinoma. 15552 (2020). 32968147 | 32968147 |
| 393 | CAPNS1 | ARP58434_P050 | Kulkarni, Y. M. et al. Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis. Analyst 138, 6986-96 (2013). 24091439 | 24091439 |
| 394 | CARS2 | ARP68165_P050 | Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-β1: Induction of Cystathionine γ-Lyase and Cystathionine β-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways. Int J Mol Sci. 22 (2021). 34769192 | 34769192 |
| 395 | CASP1 | OAAI00768 | Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora. Front Pharmacol 2022 NULL 13 805266 35431939 | 35431939 |
| 396 | CASP1 | OKEH01146 | NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis C.Mediators Inflamm69179192021NULLNovember2021 | 34840527 |
| 397 | CASP3 | OKCD06592 | Phosphaplatin Anti-tumor Effect Enhanced by Liposomes Partly via an Up-regulation of PEDF in Breast Cancer. Anticancer Res. 38, 623-646 (2018). 29374685 | 29374685 |
| 398 | CASP3 | OKEH02987 | Clinically Relevant Concentrations of Ketamine Inhibit Osteoclast Formation In Vitro in Mouse Bone Marrow Cultures. J. Cell. Biochem. 118, 914-923 (2017). 27775174 | 27775174 |
| 399 | CASP6 | OAAF05316 | Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding. J. Neurosci. Methods. 282, 20-33 (2017). 28267565 | 28267565 |
| 400 | CASP6 | OAAF05316 | Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans. Neurobiol Aging. 61, 44531 (2018). 29031088 | 29031088 |
| 401 | CASPASE-3 | AVARP00021_T100 | A scaffold-free surface culture of B16F10 murine melanoma cells based on magnetic levitation. Cytotechnology. 68, 2323-2334 (2016). 27670438 | 27670438 |
| 402 | CAT | OAAB05216 | Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med. 42, 789-798 (2018). 29717771 | 29717771 |
| 403 | CAT | OAAB05216 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
| 404 | CAT | OAEB02426 | Imatinib Is Protective Against Ischemia-Reperfusion Injury in an Ex Vivo Rabbit Model of Lung Injury. Ann Thorac Surg. 105, 950-956 (2018). 29289364 | 29289364 |
| 405 | CAT2 | ARP43766_P050 | MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters. Mol. Cell. Biochem. 419, 147-55 (2016). 27357826 | 27357826 |
| 406 | CATSPER2 | ARP35455_T100 | Kawano, N. et al. Seminal vesicle protein SVS2 is required for sperm survival in the uterus. Proc. Natl. Acad. Sci. U. S. A. 111, 4145-50 (2014). 24591616 | 24591616 |
| 407 | CAV2 | AVARP09020_P050 | Chi Sabins, N. et al. DLK1: a novel target for immunotherapeutic remodeling of the tumor blood vasculature. Mol. Ther. 21, 1958-68 (2013). 23896726 | 23896726 |
| 408 | CAV3 | OAAB03503 | Pavlović, D., McLatchie, L. M. & Shattock, M. J. The rate of loss of T-tubules in cultured adult ventricular myocytes is species dependent. Exp. Physiol. 95, 518-27 (2010). 20061354 | 20061354 |
| 409 | CB2R | ARP63486_P050 | Wilhelmsen, K. et al. The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells. J. Biol. Chem. 289, 13079-100 (2014). 24644287 | 24644287 |
| 410 | CBLL1 | ARP39622_P050 | Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev. 32, 415-429 (2018). 29535189 | 29535189 |
| 411 | CBLL1 | ARP39623_T100 | Horiuchi, K. et al. Identification of Wilms’ Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle. J. Biol. Chem. 288, 33292-302 (2013). 24100041 | 24100041 |
| 412 | CBLL1 | ARP39623_T100 | Wilms' tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences. J Biol Chem. 297, 101248 (2021). 34582888 | 34582888 |
| 413 | Cbln4 | ARP52505_P050 | Gupta, S. et al. Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. J. Pharmacol. Exp. Ther. 341, 16-23 (2012). 22220752 | 22220752 |
| 414 | CBLN4 | ARP52505_P050 | Glycosylation of Cblns attenuates their receptor binding. Brain Res. 1694, 129-139 (2018) 29782851 | 29782851 |
| 415 | CBR1 | ARP45800_P050 | Lim, S. et al. Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. Int. J. Biochem. Cell Biol. 45, 1784-93 (2013). 23732109 | 23732109 |
| 416 | CBR1 | ARP45800_P050 | Mitani, T. et al. Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells. J. Nutr. Sci. Vitaminol. (Tokyo). 60, 122-8 (2014). 24975222 | 24975222 |
| 417 | CBR2 | ARP42461_P050 | Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion. FASEB J. 33, 6226-6238 (2019). 30794439 | 30794439 |
| 418 | CBS | ARP45746_T100 | Fernandes, V. S. et al. Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck. J. Urol. 189, 1567-73 (2013). 23063804 | 23063804 |
| 419 | CBS | ARP45746_T100 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 420 | CBS | ARP45746_T100 | Markand, S. et al. Cystathionine beta synthase expression in mouse retina. Curr. Eye Res. 38, 597-604 (2013). 23470016 | 23470016 |
| 421 | CBS | ARP45746_T100 | Dahlhoff, C. et al. Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism. PLoS One 8, e57387 (2013). 23472083 | 23472083 |
| 422 | CBS | ARP45746_T100 | Porteus, C. S. et al. The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio). J. Physiol. 592, 3075-88 (2014). 24756639 | 24756639 |
| 423 | CBS | ARP45746_T100 | Geillinger, K. E. et al. Hepatic metabolite profiles in mice with a suboptimal selenium status. J. Nutr. Biochem. 25, 914-22 (2014). 24917045 | 24917045 |
| 424 | CBS | ARP45746_T100 | Yamane, S., Kanno, T., Nakamura, H., Fujino, H. & Murayama, T. Hydrogen sulfide-mediated regulation of contractility in the mouse ileum with electrical stimulation: Roles of l-cysteine, cystathionine beta-synthase, and K(+) channels. Eur. J. Pharmacol. 740, 112-20 (2014). 25008073 | 25008073 |
| 425 | CBS | ARP45746_T100 | Dahlhoff, C. et al. Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels. Mol. Metab. 3, 565-80 (2014). 25061561 | 25061561 |
| 426 | CBX4 | ARP30002_P050 | Hao, L., Midic, U., Garriga, J. & Latham, K. E. Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos. Physiol. Genomics 46, 66-80 (2014). 24280258 | 24280258 |
| 427 | CBX8 | ARP34599_P050 | Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. Cell Rep. 26, 3643-3656.e7 (2019). 30917318 | 30917318 |
| 428 | CCDC11 | ARP55454_P050 | Perles, Z. et al. A human laterality disorder associated with recessive CCDC11 mutation. J. Med. Genet. 49, 386-90 (2012). 22577226 | 22577226 |
| 429 | CCDC90A | ARP44777_P050 | Mitochondrial Ca2+ Uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses.J Cell SciNULLNULLNULLOctober2022 | 36274588 |
| 430 | CCDC9B | ARP68125_P050 | Transcriptional Induction of Cystathionine γ-Lyase, a Reactive Sulfur-Producing Enzyme, by Copper Diethyldithiocarbamate in Cultured Vascular Endothelial Cells. Int J Mol Sci. 21, NULL (2020). 32842680 | 32842680 |
| 431 | CCK | ARP33849_P050 | Talchai, C., Xuan, S., Kitamura, T., DePinho, R. A. & Accili, D. Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nat. Genet. 44, 406-12, S1 (2012). 22406641 | 22406641 |
| 432 | CCL2 | AVARP07046_P050 | Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach. Int J Mol Sci. 19, (2018). 29518977 | 29518977 |
| 433 | CCL22 | OKWB00363 | MiR-384 induces apoptosis and autophagy of non-small cell lung cancer cells through the negative regulation of Collagen a-1(X) chain gene. Biosci Rep. 39, (2019). 30442874 | 30442874 |
| 434 | CCNB3 | ARP39739_T100 | Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes. Development. 137, 1699-707 (2010). 20430745 | 20430745 |
| 435 | CCND3 | AVARP03038_P050 | Discovery of Human-Similar Gene Fusions in Canine Cancers. Cancer Res. 77, 5721-5727 (2017). 28883003 | 28883003 |
| 436 | CCR2 | ARP58409_P050 | Liang, X., Li, H. & Li, S. A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study. Mol. Biosyst. 10, 1014-22 (2014). 24492828 | 24492828 |
| 437 | CCR2 | ARP58410_P050 | CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis. Vet. Immunol. Immunopathol. 182, 52-58 (2016). 27863550 | 27863550 |
| 438 | CCR2 | OASA06081 | Bhangoo, S. et al. Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. Mol. Pain 3, 38 (2007). 18076762 | 18076762 |
| 439 | CCR2 | OASA06081 | Bhangoo, S. K., Ripsch, M. S., Buchanan, D. J., Miller, R. J. & White, F. A. Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy. Mol. Pain 5, 48 (2009). 19674450 | 19674450 |
| 440 | CCR2 | OASA06081 | Jeon, S.-M., Sung, J.-K. & Cho, H.-J. Expression of monocyte chemoattractant protein-1 and its induction by tumor necrosis factor receptor 1 in sensory neurons in the ventral rhizotomy model of neuropathic pain. Neuroscience 190, 354-66 (2011). 21712071 | 21712071 |
| 441 | CCR3 | OAAB05403 | Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils. PLoS ONE. 11, e0157186 (2016). 27275740 | 27275740 |
| 442 | CCT4 | ARP34271_P050 | Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). 22133715 | 22133715 |
| 443 | CCT4 | ARP34271_P050 | Tarkar, A. et al. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat. Genet. 45, 995-1003 (2013). 23872636 | 23872636 |
| 444 | CCT4 | ARP34271_P050 | Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis. Mol Biol Cell. 25, 1216-33 (2014). 24554764 | 24554764 |
| 445 | CCT8 | ARP45837_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 446 | CD117 | OAEE00057 | Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 66, 879-888 (2018). 30004288 | 30004288 |
| 447 | CD14 | OAEB02354 | Human annulus progenitor cells: Analyses of this viable endogenous cell population. J. Orthop. Res. 34, 1351-60 (2016). 27249627 | 27249627 |
| 448 | CD200 | ARP63444_P050 | Stem Cell-Associated Marker Expression in Canine Hair Follicles. J Histochem Cytochem. 64, 190-204 (2016). 26739040 | 26739040 |
| 449 | CD206 | OASA05048 | Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 1, 678-694 (2015). 26693174 | 26693174 |
| 450 | CD3 | OASA11552 | Natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis: a postmortem study. J Neuropathol Exp Neurol. 72, 1043-51 (2013). 24128680 | 24128680 |
| 451 | CD3 | OASA11552 | Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hamper Detection of Neurons by T Lymphocytes in the Central Nervous System. J Neuropathol Exp Neurol. 74, 791-803 (2015). 26115192 | 26115192 |
| 452 | CD34 | ARP60993_P050 | Telocytes in the hearts of Saanen goats.Microsc Res Tech548-554843March2021 | 33017500 |
| 453 | CD3G | OAAB01258 | A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes. Front Immunol. 10, 2833 (2020). 31921117 | 31921117 |
| 454 | CD40LG | ARP33831_P050 | IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle. Reproduction. 159, 503-511 (2020) 32103820 | 32103820 |
| 455 | CD44 | ARP61023_P050 | Monika Hartmann, et al. Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44. 879-90 (2015). 25652588 | 25652588 |
| 456 | CD45 | OAPA00144 | Krawetz, R. J. et al. Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture. PLoS One 7, e43616 (2012). 22952721 | 22952721 |
| 457 | CD47 | ARP63284_P050 | Nanoparticle biointerfacing by platelet membrane cloaking. Nature. 526, 118-21 (2015). 26374997 | 26374997 |
| 458 | CD47 | ARP63284_P050 | Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles. Sci Adv. 6, eaaz6108 (2020). 32258408 | 32258408 |
| 459 | CD68 | OABB00472 | Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. Int J Cancer. 138, 2700-12 (2016). 26773796 | 26773796 |
| 460 | CD68 | OABB00472 | Cellular senescence drives age-dependent hepatic steatosis. Nat Commun. 8, 15691 (2017). 28608850 | 28608850 |
| 461 | CD68 | OABB00472 | Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice. Aging Cell. 18, e12882 (2019). 30468013 | 30468013 |
| 462 | CD68 | OABB00472 | A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice. Nutrients. 11, (2019). 31330878 | 31330878 |
| 463 | CD68 | OABB00472 | FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis. JCI Insight. 5, (2020). 32102985 | 32102985 |
| 464 | CD68 | OABB00472 | c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nat Metab. 2, 1350-1367 (2020) 33168981 | 33168981 |
| 465 | CD68 | OABB00472 | Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. (2021). 33441438 | 33441438 |
| 466 | CD68 | OABB00472 | Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. (2021). 31877385 | 31877385 |
| 467 | CD68 | OKEH03503 | ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease. Acta Neuropathol. 139, 485-502 (2020). 31982938 | 31982938 |
| 468 | CD9 | ARP61171_P050 | Isolation and Characterization of Small Extracellular Vesicles from Porcine Blood Plasma, Cerebrospinal Fluid, and Seminal Plasma. Proteomes. 7, (2019). 31027284 | 31027284 |
| 469 | CD9 | OKCD00751 | ALPPL2 Is a Potential Diagnostic Biomarker for Pancreatic Cancer-Derived Extracellular Vesicles. Mol Ther Methods Clin Dev. 15, 204-210 (2019). 31687420 | 31687420 |
| 470 | CDCA7 | ARP66756_P050 | Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med. 211, 2411-23 (2014). 25385755 | 25385755 |
| 471 | CDH22 | ARP49648_P050 | Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion. Oncogene. 37, 651-662 (2018). 28991229 | 28991229 |
| 472 | CDH5 | | Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition. J Am Heart Assoc 2022 7 11 e023695 35348006 | 35348006 |
| 473 | CDK1 | OAAN02724 | The ubiquitin ligase KBTBD8 regulates PKM1 levels via Erk1/2 and Aurora A to ensure oocyte quality. Aging (Albany NY). 11, 1110-1128 (2019). 30786262 | 30786262 |
| 474 | CDK1 | OAAN02724 | The 5.8S pre-rRNA maturation factor, M-phase phosphoprotein 6, is a female fertility factor required for oocyte quality and meiosis. Cell Prolif. 53, e12769 (2020). 32003502 | 32003502 |
| 475 | CDK2 | ARP30331_P050 | The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1a and functions in cellular adaptations. FASEB J. 29, 4901-13 (2015). 26265472 | 26265472 |
| 476 | CDKN1B | OAAI00157 | MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity. Genes Dev. 34, 1210-1226 (2020) 32820040 | 32820040 |
| 477 | CDKN1B | OAEB01630 | Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells. J Ovarian Res. 9, 71 (2016). 27793176 | 27793176 |
| 478 | CDS1 | ARP45073_P050 | Croston, T. L. et al. Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart. Life Sci. 93, 313-22 (2013). 23872101 | 23872101 |
| 479 | CDT2 | OAAB00993 | Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung. Dis Model Mech. 8, 1531-42 (2015). 26471094 | 26471094 |
| 480 | CDX2 | ARP31476_P050 | Tajbakhsh, J. Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells. Methods Mol. Biol. 1052, 77-88 (2013). 23593143 | 23593143 |
| 481 | CDX4 | ARP32765_P050 | Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice. Development. 135, 2511-20 (2008). 18579683 | 18579683 |
| 482 | CDYL | ARP49096_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 483 | CEACAM6 | ARP41504_T100 | Kobayashi, M. et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br. J. Cancer 107, 1745-53 (2012). 23099808 | 23099808 |
| 484 | CEBPA | ARP57937_P050 | Borger, P. et al. Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients. J. Allergy Clin. Immunol. 123, 639-45 (2009). 19121862 | 19121862 |
| 485 | CEBPA | ARP57937_P050 | Miglino, N., Roth, M., Tamm, M. & Borger, P. House dust mite extract downregulates C/EBPa in asthmatic bronchial smooth muscle cells. Eur. Respir. J. 38, 50-8 (2011). 21109558 | 21109558 |
| 486 | CEMIP | ARP42526_P050 | KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions. Glycobiology. 28, 958-967 (2018). 30007349 | 30007349 |
| 487 | Cep55 | ARP46271_P050 | Chang, Y.-C. et al. Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes. J. Cell. Biochem. 109, 1274-85 (2010). 20186884 | 20186884 |
| 488 | CERK | OKCD09200 | Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple-negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways. Cancer Cell Int 2021 1 21 42 33430896 | 33430896 |
| 489 | CERS1 | ARP49654_P050 | Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis. Cancer Res. 77, 5272-5286 (2017). 28775166 | 28775166 |
| 490 | CERS2 | ARP32609_P050 | Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration. J Biomed Sci. 25, 40 (2018). 29720183 | 29720183 |
| 491 | CFL1 | OKEH01091 | Tandem Mass Tag-Based Serum Proteome Profiling for Biomarker Discovery in Young Duchenne Muscular Dystrophy Boys. ACS Omega. 5, 26504-26517 (2020). 33110978 | 33110978 |
| 492 | CGI-58 | OAEB01343 | Skinner, J. R., Harris, L.-A. L. S., Shew, T. M., Abumrad, N. A. & Wolins, N. E. Perilipin 1 moves between the fat droplet and the endoplasmic reticulum. Adipocyte 2, 80-6 (2013). 23805403 | 23805403 |
| 493 | CHAF1B | ARP45826_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 494 | CHAF1B | ARP45826_P050 | The GABAAα5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome. Neuroscience. 372, 192-212 (2018) 29292072 | 29292072 |
| 495 | CHCHD1 | ARP53491_P050 | Koc, E. C. et al. Identification and characterization of CHCHD1, AURKAIP1, and CRIF1 as new members of the mammalian mitochondrial ribosome. Front. Physiol. 4, 183 (2013). 23908630 | 23908630 |
| 496 | CHCHD3 | ARP57039_P050 | Ott, C. et al. Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes. Mol. Cell. Biol. 32, 1173-88 (2012). 22252321 | 22252321 |
| 497 | CHCHD3 | ARP57039_P050 | Darshi, M., Trinh, K. N., Murphy, A. N. & Taylor, S. S. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J. Biol. Chem. 287, 39480-91 (2012). 23019327 | 23019327 |
| 498 | CHCHD3 | OAEB01302 | SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 8, 1019-38 (2016). 27390132 | 27390132 |
| 499 | CHCHD3 | OAEB01622 | Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 3, e1700677 (2017). 28835921 | 28835921 |
| 500 | CHCHD3 | ARP33059_P050 | QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife 2016 NULL 5 NULL 27623147 | 27623147 |
| 501 | CHD4 | ARP34372_P050 | Mta2 promotes Tipin-dependent maintenance of replication fork integrity. Cell Cycle. 13, 2120-8 (2014). 24830473 | 24830473 |
| 502 | CHES1 | ARP32841_T100 | Huot, G. et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol. Biol. Cell 25, 554-65 (2014). 24403608 | 24403608 |
| 503 | CHI3L1 | ARP51929_P050 | Kao, T.-H., Peng, Y.-J., Tsou, H.-K., Salter, D. M. & Lee, H.-S. Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation. J. Neurosurg. Spine 1-9 (2014). doi:10.3171/2014.6.SPINE13756 25062286 | 25062286 |
| 504 | CHIA | ARP42601_P050 | Fukushima, T., Nashida, T., Haga-Tsujimura, M. & Mataga, I. Chitinase expression in parotid glands of non-obese diabetic mice. Oral Dis. 18, 506-12 (2012). 22309644 | 22309644 |
| 505 | CHIA | ARP42601_P050 | Strobel, S., Roswag, A., Becker, N. I., Trenczek, T. E. & Encarnação, J. A. Insectivorous bats digest chitin in the stomach using acidic mammalian chitinase. PLoS One 8, e72770 (2013). 24019876 | 24019876 |
| 506 | CHML | OAAF04109 | Li, J. et al. Proteomic-based approach for biomarkers discovery in early detection of invasive urothelial carcinoma. Proteomics. Clin. Appl. 2, 78-89 (2008). 21136781 | 21136781 |
| 507 | CHMP4B | ARP53340_P050 | Bodon, G. et al. Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane. J. Biol. Chem. 286, 40276-86 (2011). 21926173 | 21926173 |
| 508 | CHRNA4 | ARP34965_P050 | Ishizuka, T., Ozawa, A., Goshima, H. & Watanabe, Y. Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells. Life Sci. 90, 637-48 (2012). 22483693 | 22483693 |
| 509 | CHRNA9 | AVARP13019_P050 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
| 510 | CHST1 | ARP45495_T100 | Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors. Mol Cell Proteomics. 20, 100150 (2021). 34555499 | 34555499 |
| 511 | CHST14 | ARP48994_P050 | The phenotype of the musculocontractural type of Ehlers-Danlos syndrome due to CHST14 mutations. Am. J. Med. Genet. A. 170A, 103-15 (2016). 26373698 | 26373698 |
| 512 | CHST4 | ARP35787_T100 | Carbohydrate Sulfotransferase 4 Inhibits the Progression of Hepatitis B Virus-Related Hepatocellular Carcinoma and Is a Potential Prognostic Marker in Several Tumors. Front Oncol. 10, 554331 (2020). 33178582 | 33178582 |
| 513 | CILP | OAEB01146 | CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling. Circ Cardiovasc Genet. 9, 14-25 (2016). 26578544 | 26578544 |
| 514 | CIRBP | ARP40348_P050 | A Novel Candidate Gene for Temperature-Dependent Sex Determination in the Common Snapping Turtle. Genetics. 203, 557-71 (2016). 26936926 | 26936926 |
| 515 | CIRBP | ARP40348_P050 | An Immunohistochemical Approach to Identify the Sex of Young Marine Turtles. Anat Rec (Hoboken) (2017). 28296279 | 28296279 |
| 516 | CK15 | AVARP00005_P050 | Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). 18632593 | 18632593 |
| 517 | CKAP4 | ARP46790_P050 | Clark, R. et al. Comparative genomic and proteomic analysis of cytoskeletal changes in dexamethasone-treated trabecular meshwork cells. Mol. Cell. Proteomics 12, 194-206 (2013). 23105009 | 23105009 |
| 518 | CKAP4 | OKCA01191 | Zhenhua Du, et al. Quantitative proteomics identifies a plasma multi-protein model for detection of hepatocellular carcinoma. 15552 (2020). 32968147 | 32968147 |
| 519 | CKB | OKEH06448 | Creatine kinase/a-crystallin interaction functions in cataract development. Biochem Biophys Rep. 22, 100748 (2020). 32154391 | 32154391 |
| 520 | CKM | OKCD01481 | Creatine kinase/a-crystallin interaction functions in cataract development. Biochem Biophys Rep. 22, 100748 (2020). 32154391 | 32154391 |
| 521 | CKMT2 | ARP41478_T100 | Choudhuri, A., Maitra, U. & Evans, T. Translation initiation factor eif3h targets specific transcripts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. U. S. A. 110, 9818-23 (2013). 23716667 | 23716667 |
| 522 | CLCF1 | OKEH04677 | Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases. Immunity. 51, 949-965.e6 (2019). 31653482 | 31653482 |
| 523 | CLCN3 | ARP35504_T100 | Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). 21050068 | 21050068 |
| 524 | CLCN6 | ARP35334_T100 | Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). 21050068 | 21050068 |
| 525 | CLDN1 | ARP33623_P050 | Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165.Cell Physiol Biochem1493-1513424July2017 | 28719888 |
| 526 | CLDN13 | ARP33616_T100 | Fujita, H. et al. Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine. J. Histochem. Cytochem. 54, 933-44 (2006). 16651389 | 16651389 |
| 527 | CLDN16 | ARP33632_P050 | Wang, F. E. et al. MicroRNA-204/211 alters epithelial physiology. FASEB J. 24, 1552-71 (2010). 20056717 | 20056717 |
| 528 | CLDN16 | ARP33632_P050 | Peng, S., Rao, V. S., Adelman, R. A. & Rizzolo, L. J. Claudin-19 and the barrier properties of the human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 52, 1392-403 (2011). 21071746 | 21071746 |
| 529 | CLDN5 | ARP33627_P050 | Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier. Oncotarget. 7, 63839-63855 (2016). 27588479 | 27588479 |
| 530 | CLDN9 | ARP33617_T100 | Abuazza, G. et al. Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins. Am. J. Physiol. Renal Physiol. 291, F1132-41 (2006). 16774906 | 16774906 |
| 531 | CLDN9 | ARP33617_T100 | Carrozzino, F., Pugnale, P., Féraille, E. & Montesano, R. Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression. Am. J. Physiol. Cell Physiol. 297, C775-87 (2009). 19605737 | 19605737 |
| 532 | CLIC1 | ARP35045_T100 | Yang, J.-Y. et al. Chloride intracellular channel 1 regulates osteoblast differentiation. Bone 45, 1175-85 (2009). 19703605 | 19703605 |
| 533 | CLIC5 | ARP35262_T100 | Li, F.-N. et al. Chloride intracellular channel 5 modulates adipocyte accumulation in skeletal muscle by inhibiting preadipocyte differentiation. J. Cell. Biochem. 110, 1013-21 (2010). 20564201 | 20564201 |
| 534 | CLIC5 | ARP35263_P050 | The chloride intracellular channel 5A stimulates podocyte Rac1, protecting against hypertension-induced glomerular injury. Kidney Int. 89, 833-47 (2016). 26924049 | 26924049 |
| 535 | CLIC5 | ARP35263_T100 | Both CLIC4 and CLIC5A activate ERM proteins in glomerular endothelium. Am. J. Physiol. Renal Physiol. 311, F945-F957 (2016). 27582103 | 27582103 |
| 536 | CLK1 | ARP52021_P050 | Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). 23604472 | 23604472 |
| 537 | CLK1 | ARP52021_P050 | Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Mol. Cell. 63, 218-28 (2016). 27397683 | 27397683 |
| 538 | CLK1 | ARP52021_P050 | Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nat Commun. 12, 4507 (2021) 34301951 | 34301951 |
| 539 | CLK4 | ARP30645_P050 | Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). 23604472 | 23604472 |
| 540 | CLOSTRIDIUM PERFRINGENS | OASA07164 | Gut microbiota and age shape susceptibility to clostridial enteritis in lorikeets under human care. Anim Microbiome. 4, 7 (2022). 35000619 | 35000619 |
| 541 | CLPB | ARP53790_P050 | Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis. Nat Commun. 9, 866 (2018). 29491361 | 29491361 |
| 542 | CLU | ARP61142_P050 | Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in models of cartilage degradation. J Orthop Res. (2020) 32725904 | 32725904 |
| 543 | CLUH | ARP70642_P050 | CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 216, 675-693 (2017). 28188211 | 28188211 |
| 544 | CLUH | ARP70642_P050 | Characterization of Factors Involved in Localized Translation Near Mitochondria by Ribosome-Proximity Labeling. Front Cell Dev Biol. 7, 305 (2020). 31929983 | 31929983 |
| 545 | CLUH | ARP70642_P050 | CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy. EMBO J. 39, e102731 (2020). 32149416 | 32149416 |
| 546 | CLUH | ARP48286_T100 | Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria. Nat Commun 2022 1 13 1582 35332133 | 35332133 |
| 547 | CLUH | OAAI00735 | CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife 2022 NULL 11 NULL 35559794 | 35559794 |
| 548 | CNDP1 | OKEH00851 | Quantitative Comparative Proteomics Reveals Candidate Biomarkers for the Early Prediction of Gestational Diabetes Mellitus: A Preliminary Study. In Vivo. 34, 517-525 (2020). 32111749 | 32111749 |
| 549 | CNOT7 | ARP39026_P050 | Maragozidis, P. et al. Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker. Acta Haematol. 128, 39-46 (2012). 22614729 | 22614729 |
| 550 | COL1A1 | OAAB10798 | Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome. EBioMedicine. 63, 103162 (2020). 33340991 | 33340991 |
| 551 | COL1A1 | OAAB10798 | Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 131 (2021). 33465051 | 33465051 |
| 552 | COL1A1 | OKEH00542 | Validating candidate biomarkers for different stages of non-alcoholic fatty liver disease. Medicine (Baltimore). 99, e21463 (2020). 32898995 | 32898995 |
| 553 | COL1A2 | OAAF01757 | Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342. FASEB J. 30, 4214-4226 (2016). 27623927 | 27623927 |
| 554 | COL1A2 | OAAF02899 | Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Ia2 expression via miR-342. FASEB J. 30, 4214-4226 (2016). 27623927 | 27623927 |
| 555 | COL6A3 | OAAF02910 | Isolation and characterisation of a novel trophoblast side-population from first trimester placentae. Reproduction. 150, 449-62 (2015). 26248480 | 26248480 |
| 556 | Collagen I | | CNS fibroblasts form a fibrotic scar in response to immune cell infiltration. Nat Neurosci 2021 2 24 234-244 33526922 | 33526922 |
| 557 | Collagen Type I | OAMA03716 | Novel high-throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP2 and EP4 receptors. PLoS One. 13, e0207872 (2018). 30485339 | 30485339 |
| 558 | Collagen Type I | OAMA03716 | GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1. PLoS One. 15, e0228195 (2020). 32053631 | 32053631 |
| 559 | COPA | ARP51893_P050 | Ting, C.-H. et al. The spinal muscular atrophy disease protein SMN is linked to the Golgi network. PLoS One 7, e51826 (2012). 23284781 | 23284781 |
| 560 | COPA | ARP51893_P050 | a-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth. Hum. Mol. Genet. 24, 7295-307 (2015). 26464491 | 26464491 |
| 561 | COQ2 | ARP47180_P050 | New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats. Mamm. Genome. 26, 619-29 (2015). 26296322 | 26296322 |
| 562 | CORO1A | ARP38899_T100 | Differential proteomic analysis of tibial subchondral bone from male and female guinea pigs with spontaneous osteoarthritis. Exp Ther Med. 21, 633 (2021) 33968164 | 33968164 |
| 563 | COUP-TFII | ARP39466_T100 | Cho, K., Yi, H., Tserentsoodol, N., Searle, K. & Ferreira, P. A. Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. Dis. Model. Mech. 3, 595-604 (2010). 20682751 | 20682751 |
| 564 | COX15 | ARP46442_T100 | Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. J. Biol. Chem. 291, 10411-25 (2016). 26940873 | 26940873 |
| 565 | COX4I1 | ARP42784_T100 | Snyder, A. M. et al. Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J. Neuropathol. Exp. Neurol. 68, 1193-9 (2009). 19816198 | 19816198 |
| 566 | COX4l1 | ARP42784_T100 | Geerling, J. J. et al. Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice. Diabetes 63, 880-91 (2014). 24270984 | 24270984 |
| 567 | CPA3 | OKCD01671 | Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin. J Leukoc Biol. (2021) 34057753 | 34057753 |
| 568 | CPEB2 | ARP41186_P050 | CPEB2 Is Necessary for Proper Porcine Meiotic Maturation and Embryonic Development. Int J Mol Sci. 19, (2018). 30322039 | 30322039 |
| 569 | CPEB4 | ARP41024_P050 | Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 560, 441-446 (2018). 30111840 | 30111840 |
| 570 | C-PEPTIDE | OKEH00454 | Persistence of Coxsackievirus B4 in Pancreatic β Cells Disturbs Insulin Maturation, Pattern of Cellular Proteins, and DNA Methylation. Microorganisms 2021 6 9 NULL 34067388 | 34067388 |
| 571 | CPR | ARP44362_P050 | Lee, J. W., Kim, Y. H., Yoon, S. & Lee, S. K. Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne Benzo(a)pyrene exposure: implications for biomarker determination. Environ. Toxicol. (2012). doi:10.1002/tox.21833 23192953 | 23192953 |
| 572 | CPT1 | ARP44796_P050 | Laghezza, A. et al. New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor a/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression. J. Med. Chem. 56, 60-72 (2013). 23171045 | 23171045 |
| 573 | CPT1A | ARP44796_P050 | The contribution of the citrate pathway to oxidative stress in Down syndrome. Immunology. 149, 423-431 (2016). 27502741 | 27502741 |
| 574 | CPT1A | ARP44796_P050 | New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity. Eur J Med Chem. 127, 379-397 (2017). 28076827 | 28076827 |
| 575 | CPT1A | ARP44796_P050 | Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study. Mol Med Rep. 23 (2021) 33760189 | 33760189 |
| 576 | CPT1A | ARP44796_P050 | The role of CD36-Fabp4-PPARγ in skeletal muscle involves insulin resistance in intrauterine growth retardation mice with catch-up growth. BMC Endocr Disord. 22, 10 (2022). 34983495 | 34983495 |
| 577 | CPT1A | OKEH00404 | Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression. Life Sci Alliance. 3, NULL (2020). 32487689 | 32487689 |
| 578 | CPT1B | ARP46444_P050 | Wolf-Johnston, A. S. et al. Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium. Life Sci. 91, 1065-9 (2012). 22569297 | 22569297 |
| 579 | CPT1B | ARP46444_P050 | Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats. Pediatr. Res. 80, 128-35 (2016). 26991264 | 26991264 |
| 580 | CPT1B | ARP46444_P050 | Enhancement of Glucose Metabolism via PGC-1a Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia. Front Physiol. 7, 219 (2016). 27375497 | 27375497 |
| 581 | CPT2 | OAAN00972 | Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation. Aging (Albany NY). 12, 19677-19700 (2020). 33024056 | 33024056 |
| 582 | CPT2 | OAAN00972 | A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Sci Adv. 7, eabi7514 (2021). 34559558 | 34559558 |
| 583 | CRBN | ARP56882_P050 | Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity. Br J Haematol. 164, 233-44 (2014). 24206017 | 24206017 |
| 584 | CRBN | ARP56882_P050 | HDAC6‑selective inhibitor synergistically enhances the anticancer activity of immunomodulatory drugs in multiple myeloma. Int J Oncol. 55, 499-512 (2019). 31268156 | 31268156 |
| 585 | CREB3L1 | ARP36109_T100 | CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells. J Cell Sci. 130, 4155-4167 (2017). 29093023 | 29093023 |
| 586 | CREB3L2 | ARP34673_T100 | Sievert, A. J. et al. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol. 19, 449-58 (2009). 19016743 | 19016743 |
| 587 | CREB3L2 | ARP34673_T100 | Fox, R. M., Hanlon, C. D. & Andrew, D. J. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J. Cell Biol. 191, 479-92 (2010). 21041443 | 21041443 |
| 588 | CREB3L2 | ARP34673_T100 | Lynch, J. M. et al. A thrombospondin-dependent pathway for a protective ER stress response. Cell 149, 1257-68 (2012). 22682248 | 22682248 |
| 589 | CREB3L2 | ARP34673_T100 | CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells. J Cell Sci. 130, 4155-4167 (2017). 29093023 | 29093023 |
| 590 | CREBBP | ARP43609_P050 | p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair. Cancers (Basel). 13 (2021). 33799418 | 33799418 |
| 591 | CREBBP | ARP43609_P050 | p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair. Cancers (Basel). 13 (2021). 34884992 | 34884992 |
| 592 | CREM | ARP34777_T100 | Sunahori, K., Juang, Y.-T. & Tsokos, G. C. Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity. J. Immunol. 182, 1500-8 (2009). 19155497 | 19155497 |
| 593 | CRH | OKEH00623 | LUMAN/CREB3 Plays a Dual Role in Stress Responses as a Cofactor of the Glucocorticoid Receptor and a Regulator of Secretion. Front Mol Neurosci. 11, 352 (2018). 30337854 | 30337854 |
| 594 | CRH | OKEH00623 | Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome. Sci Rep 2022 1 12 8413 35589861 | 35589861 |
| 595 | CRHR1 | ARP63607_P050 | Proton Sensitivity of Corticotropin-Releasing Hormone Receptor 1 Signaling to Proopiomelanocortin in Male Mice. Endocrinology. 160, 276-291 (2019). 30535142 | 30535142 |
| 596 | CRHR1 | OAEB02329 | Control of locomotor speed, arousal, and hippocampal theta rhythms by the nucleus incertus. Nat Commun. 11, 262 (2020). 31937768 | 31937768 |
| 597 | CRHR1 | OASG01837 | Somatostatin receptor subtype 5 modifies hypothalamic-pituitary-adrenal axis stress function. JCI Insight. 3, (2018). 30282821 | 30282821 |
| 598 | CRHR1 | OASG01837 | Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells. Int J Mol Sci. 22 (2021) 33925368 | 33925368 |
| 599 | CRISP3 | OKCD08775 | A Combined CRISP3 and SPINK1 Prognostic Grade in EPS-Urine and Establishment of Models to Predict Prognosis of Patients With Prostate Cancer. Front Med (Lausanne) 2022 NULL 9 832415 35252264 | 35252264 |
| 600 | CRLS | ARP49444_P050 | Croston, T. L. et al. Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart. Life Sci. 93, 313-22 (2013). 23872101 | 23872101 |
| 601 | CRP | OKCD01339 | Association between the Inflammatory Potential of Diet and Stress among Female College Students. Nutrients. 12, NULL (2020). 32785011 | 32785011 |
| 602 | CRP | OKCD06859 | Interleukin 8 and Pentaxin (C-Reactive Protein) as Potential New Biomarkers of Bovine Tuberculosis. J Clin Microbiol. 57, (2019). 31340991 | 31340991 |
| 603 | CRP | OKEH04495 | Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics. J Proteome Res. 19, 1258-1266 (2020). 32037835 | 32037835 |
| 604 | CRY1 | ARP59758_P050 | Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles. Proc. Natl. Acad. Sci. U.S.A. 113, 6053-8 (2016). 27166423 | 27166423 |
| 605 | CRY2 | ARP52398_P050 | Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles. Proc. Natl. Acad. Sci. U.S.A. 113, 6053-8 (2016). 27166423 | 27166423 |
| 606 | CSDA | OAAB10985 | Babu, E. et al. Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene 30, 4026-37 (2011). 21473684 | 21473684 |
| 607 | CSE | ARP31932_P050 | Fernandes, V. S. et al. Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck. J. Urol. 189, 1567-73 (2013). 23063804 | 23063804 |
| 608 | CSE | ARP46067_P050 | Porteus, C. S. et al. The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio). J. Physiol. 592, 3075-88 (2014). 24756639 | 24756639 |
| 609 | CSE | ARP46067_P050 | Kumai, Y., Porteus, C. S., Kwong, R. W. M. & Perry, S. F. Hydrogen sulfide inhibits Na(+) uptake in larval zebrafish, Danio rerio. Pflugers Arch. doi:10.1007/s00424-014-1550-y (2014). 24939700 | 24939700 |
| 610 | CSF1R | OPPA01429 | Inhaled Seralutinib Exhibits Potent Efficacy in Models of Pulmonary Arterial Hypertension. Eur Respir J 2022 NULL NULL NULL 35680144 | 35680144 |
| 611 | CSN1S1 | OAAB03556 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
| 612 | CSN2 | ARP38431_T100 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
| 613 | CSN6 | ARP59350_P050 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
| 614 | CSN8 | ARP52242_P050 | Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). 22956996 | 22956996 |
| 615 | CSRP3 | ARP34181_P050 | Roberts, M. D., Childs, T. E., Brown, J. D., Davis, J. W. & Booth, F. W. Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running. J. Appl. Physiol. 112, 1291-9 (2012). 22282489 | 22282489 |
| 616 | Cst6 | ARP53533_P050 | Veniaminova, N. A. et al. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development 140, 4870-80 (2013). 24198274 | 24198274 |
| 617 | CST6 | ARP53533_P050 | Dynamics of Lgr6⁺ Progenitor Cells in the Hair Follicle, Sebaceous Gland, and Interfollicular Epidermis. Stem Cell Reports. 5, 843-55 (2015). 26607954 | 26607954 |
| 618 | CTCF | ARP38820_P050 | Folding Keratin Gene Clusters during Skin Regional Specification. Dev Cell. 53, 561-576.e9 (2020) 32516596 | 32516596 |
| 619 | CTGF | OKEH00020 | Cultured Neonatal Rat Cardiomyocytes Continue Beating Through Upregulation of CTGF Gene Expression. J Nippon Med Sch 2020 5 87 268-276 33311008 | 33311008 |
| 620 | CTH | ARP46067_P050 | An emerging role for gasotransmitters in the control of breathing and ionic regulation in fish. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 186, 145-59 (2016). 26660653 | 26660653 |
| 621 | CTNNB1 | P100601_P050 | Repair of massively defected hemi-joints using demineralized osteoarticular allografts with protected cartilage. J Mater Sci Mater Med. 26, 227 (2015). 26319778 | 26319778 |
| 622 | CTNNB1 | OKCD07069 | Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression. Aging Dis 2022 2 13 583-613 35371600 | 35371600 |
| 623 | CTSB | OKEH00430 | Oral Fluid Biomarkers for Diagnosing Gingivitis in Human: A Cross-Sectional Study. J Clin Med. 9 (2020) 32503210 | 32503210 |
| 624 | CTSC | ARP60116_P050 | Cathepsin B Is Upregulated and Mediates ECM Degradation in Colon Adenocarcinoma HT29 Cells Overexpressing Snail. Cells. 8, (2019). 30818851 | 30818851 |
| 625 | CTSD | ARP41481_P050 | The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. J. Cell. Sci. 128, 3068-81 (2015). 26163492 | 26163492 |
| 626 | CTSG | OKCD08583 | The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae. Front Cell Infect Microbiol. 7, 161 (2017). 28516066 | 28516066 |
| 627 | CTXII | OKEH02711 | Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models. PLoS One. 14, e0223244 (2019). 31603905 | 31603905 |
| 628 | CXCL1 | OKCD05713 | Pharmacological perturbation of CXCL1 signaling alleviates neuropathogenesis in a model of HEVA71 infection. Nat Commun 2022 1 13 890 35173169 | 35173169 |
| 629 | CXCL12 | AVARP07031_P050 | Yin, J. & Seeberger, P. H. Applications of heparin and heparan sulfate microarrays. Methods Enzymol. 478, 197-218 (2010). 20816481 | 20816481 |
| 630 | CXCL12 | AVARP07031_P050 | Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization. Am J Physiol Renal Physiol. 316, F1016-F1025 (2019). 30892933 | 30892933 |
| 631 | CXCL12 | OAAB09710 | de Paz, J. L. et al. Profiling heparin-chemokine interactions using synthetic tools. ACS Chem. Biol. 2, 735-44 (2007). 18030990 | 18030990 |
| 632 | CXCL14 | AVARP07023_P050 | Takahashi, M. et al. CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. Biochem. Biophys. Res. Commun. 364, 1037-42 (2007). 17971304 | 17971304 |
| 633 | CXCL14 | AVARP07023_P050 | Lietz, R. et al. Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection. J. Virol. 86, 1706-16 (2012). 22090142 | 22090142 |
| 634 | CXCL14 | AVARP07023_P050 | Perrone, C. E. et al. Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle. J. Nutrigenet. Nutrigenomics 5, 132-57 (2012). 23052097 | 23052097 |
| 635 | CXCL3 | AVARP07037_T100 | Cheng, C.-F. et al. Profiling motility signal-specific genes in primary human keratinocytes. J. Invest. Dermatol. 128, 1981-90 (2008). 18323786 | 18323786 |
| 636 | CXCL3 | OKEH02982 | Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model. e0232230 (2020). 32340025 | 32340025 |
| 637 | CXCL9 | OAAB02538 | Markosyan, N. et al. Mammary Carcinoma Cell Derived Cyclooxygenase 2 Suppresses Tumor Immune Surveillance by Enhancing Intratumoral Immune Checkpoint Activity. Breast Cancer Res. 15, R75 (2013). 24004819 | 24004819 |
| 638 | CXCR4 | ARP30799_P050 | Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization. Am J Physiol Renal Physiol. 316, F1016-F1025 (2019). 30892933 | 30892933 |
| 639 | CXCR4 | OKEH01535 | Protective Effect of β-Glucogallin on Damaged Cataract Against Methylglyoxal Induced Oxidative Stress in Cultured Lens Epithelial Cells. Med Sci Monit. 25, 9310-9318 (2019). 31811113 | 31811113 |
| 640 | CYBB | OABB00620 | Different signalling in infarcted and non-infarcted areas of rat failing hearts: A role of necroptosis and inflammation. J Cell Mol Med. 23, 6429-6441 (2019). 31328381 | 31328381 |
| 641 | Cyc1 | ARP51993_P050 | Qattan, A. T., Radulovic, M., Crawford, M. & Godovac-Zimmermann, J. Spatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cells. J. Proteome Res. 11, 6080-101 (2012). 23051583 | 23051583 |
| 642 | CYP11B2 | ARP41750_P050 | Doi, M. et al. Isoform-specific monoclonal antibodies against 3beta-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism. J. Clin. Endocrinol. Metab. 99, E257-62 (2014). 24423300 | 24423300 |
| 643 | CYP19A1 | OASA02666 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
| 644 | CYP1B1 | ARP51761_P050 | Wang, X., Hawkins, B. T. & Miller, D. S. Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. FASEB J. 25, 644-52 (2011). 21048045 | 21048045 |
| 645 | CYP1B1 | ARP51761_P050 | Staršíchová, A. et al. TGF-beta1 signaling plays a dominant role in the crosstalk between TGF-beta1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells. Cell. Signal. 24, 1665-76 (2012). 22560882 | 22560882 |
| 646 | CYP21 | OKEH04241 | Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice. J Lipid Res. 61, 1308-1319 (2020). 32669383 | 32669383 |
| 647 | CYP21A2 | ARP60144_P050 | Pregnancy-associated changes of peroxisome proliferator-activated receptor delta (PPARD) and cytochrome P450 family 21 subfamily A member 2 (CYP21A2) expression in the bovine corpus luteum. J Reprod Dev. 66, 205-213 (2020). 32037375 | 32037375 |
| 648 | CYP24A1 | OABB02030 | Hiroki Maruyama, et al. Low bone mineral density due to secondary hyperparathyroidism in the GlatmTg(CAG-A4GALT) mouse model of Fabry disease. 365-381 (2020). 32617522 | 32617522 |
| 649 | CYP26B1 | ARP57351_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism.iScience104823258August2022 | 35992092 |
| 650 | CYP3A4 | ARP51349_P050 | Werk, A. N. et al. Identification and Characterization of a Defective CYP3A4 Genotype in a Kidney Transplant Patient With Severely Diminished Tacrolimus Clearance. Clin. Pharmacol. Ther. 95, 416-22 (2014). 24126681 | 24126681 |
| 651 | CYP3A7 | ARP41801_T100 | Van Peer, E. et al. Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation. Basic Clin. Pharmacol. Toxicol. 114, 387-94 (2014). 24224644 | 24224644 |
| 652 | CYSTEINE | OAED00119 | Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation. Cell Metab. 31, 909-919.e8 (2020) 32275862 | 32275862 |
| 653 | CYTB | ARP50256_P050 | CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease. Am J Hum Genet. 96, 121-35 (2015). 25574826 | 25574826 |
| 654 | DAGLA | OAEB01139 | Phosphoproteomic Analysis of Subcutaneous and Omental Adipose Tissue Reveals Increased Lipid Turnover in Dairy Cows Supplemented with Conjugated Linoleic Acid. Int J Mol Sci. 22 (2021). 33810070 | 33810070 |
| 655 | DAZAP1 | ARP41161_P050 | Hayakawa, H. et al. Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochem. Biophys. Res. Commun. 403, 220-4 (2010). 21073862 | 21073862 |
| 656 | DBH | OKEH05500 | Park G., Jung Y.S., Park M.K., Yang CH, Kim, Y.U. Melatonin inhibits attention-deficit/hyperactivity disorder caused by atopic dermatitis-induced psychological stress in an NC/Nga atopic-like mouse model. Sci Rep. 2018 Oct 8; 8(1):14981. 30297827 | 30297827 |
| 657 | DBP | ARP31587_P050 | Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction. J. Biol. Chem. 291, 4913-27 (2016). 26728457 | 26728457 |
| 658 | DBP | ARP31587_P050 | Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts b-cell Function. EBioMedicine. (2017). 28389215 | 28389215 |
| 659 | DBP | ARP32195_P050 | Nakabayashi, H. et al. Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1beta gene expression in pancreatic islet beta-cells. Biochem. Biophys. Res. Commun. 434, 370-5 (2013). 23567972 | 23567972 |
| 660 | DBP | ARP32195_P050 | Okazaki, H. et al. Circadian regulation of mTOR by the ubiquitin pathway in renal cell carcinoma. Cancer Res. 74, 543-51 (2014). 24253377 | 24253377 |
| 661 | DBP | ARP32195_P050 | Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats. Neurotox Res. 35, 421-431 (2019). 30328585 | 30328585 |
| 662 | DCK | ARP51775_P050 | Bieghs, L. et al. The effects of forodesine in murine and human multiple myeloma cells. Adv. Hematol. 2010, 131895 (2010). 20981156 | 20981156 |
| 663 | DCST1 | ARP43421_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22030471 | 22030471 |
| 664 | DCUN1D2 | ARP68256_P050 | Concentration of neddylation-related molecules in paranodal myelin of the peripheral nervous system. Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. 92, 56-68 (2016). 26860454 | 26860454 |
| 665 | DCUN1D2 | ARP68256_P050 | A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation. Nat Commun. 8, 1150 (2017). 29074978 | 29074978 |
| 666 | DDIT3 | ARP43806_P050 | Sex Hormone Binding Globulin (SHBG) Mitigates ER Stress in Hepatocytes In Vitro and Ex Vivo. Cells 2021 4 10 NULL 33808055 | 33808055 |
| 667 | DDX19A | ARP36455_T100 | Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction. Nucleic Acids Res. 49, 8261-8276 (2021). 34232997 | 34232997 |
| 668 | DDX21 | ARP36374_P050 | Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). 22174317 | 22174317 |
| 669 | DDX21 | ARP36374_P050 | De Wever, V. et al. Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS One 7, e39510 (2012). 22761809 | 22761809 |
| 670 | DDX21 | ARP36375_T100 | Romanova, L. et al. Critical role of nucleostemin in pre-rRNA processing. J. Biol. Chem. 284, 4968-77 (2009). 19106111 | 19106111 |
| 671 | DDX21 | ARP36375_T100 | Miyazawa, N. et al. Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA. Genes Cells 19, 273-86 (2014). 24495227 | 24495227 |
| 672 | DDX5 | ARP36365_T100 | Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). 22174317 | 22174317 |
| 673 | DDX5 | ARP36365_T100 | The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1a and functions in cellular adaptations. FASEB J. 29, 4901-13 (2015). 26265472 | 26265472 |
| 674 | DDX60L | ARP68258_P050 | DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture. J. Virol. 89, 10548-68 (2015). 26269178 | 26269178 |
| 675 | DEK | OAAB05777 | Clawson, G. A., Bui, V., Xin, P., Wang, N. & Pan, W. Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins. J. Cell. Biochem. 105, 81-8 (2008). 18452160 | 18452160 |
| 676 | DEK | OAAB05777 | Privette Vinnedge, L. M. et al. The human DEK oncogene stimulates beta-catenin signaling, invasion and mammosphere formation in breast cancer. Oncogene 30, 2741-52 (2011). 21317931 | 21317931 |
| 677 | DEK | P100637_T100 | Wang, N. et al. Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways. PLoS One 7, e39446 (2012). 22761798 | 22761798 |
| 678 | DGCR8 | ARP40984_P050 | Kye, M. J. et al. NMDA mediated contextual conditioning changes miRNA expression. PLoS One 6, e24682 (2011). 21931811 | 21931811 |
| 679 | DGCR8 | ARP40984_P050 | Van Duyne, R. et al. Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery. PLoS One 7, e40662 (2012). 22808228 | 22808228 |
| 680 | DGCR8 | ARP40984_P050 | DGCR8 is essential for tumor progression following PTEN loss in the prostate. EMBO Rep. 16, 1219-32 (2015). 26206718 | 26206718 |
| 681 | DHH | OKEH03264 | VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. (2020) 33299122 | 33299122 |
| 682 | DHX34 | ARP36417_P050 | Histamine receptors mediate contraction of reticular groove smooth muscle of adult goats.Anat Histol Embryol440-450494July2020 | 32128873 |
| 683 | DHX9 | ARP36343_P050 | Kawai, S. & Amano, A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J. Cell Biol. 197, 201-8 (2012). 22492723 | 22492723 |
| 684 | Diacylglycerol | OKEH02607 | DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache. Front Pharmacol. 11, 615028 (2021). 33584293 | 33584293 |
| 685 | Dihydrotestosterone | OKEH02531 | Hair growth-promotion effects at the cellular level and antioxidant activity of the plant-based extract Phyllotex™. Heliyon. 7, e07888 (2021). 34522800 | 34522800 |
| 686 | DKK3 | OKCD02498 | Bone secreted factors induce cellular quiescence in prostate cancer cells. Sci Rep. 9, 18635 (2019). 31819067 | 31819067 |
| 687 | DKK3 | OKCD02498 | A combined bioinformatics, experimental and clinical approach to identify novel cardiac-specific heart failure biomarkers: is Dickkopf-3 (DKK3) a possible candidate?. Eur J Heart Fail. 22, 2065-2074 (2020). 32809235 | 32809235 |
| 688 | DLK | ARP46375_P050 | Zhou, G. et al. Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. Meat Sci. 86, 440-50 (2010). 20573458 | 20573458 |
| 689 | DLK2 | ARP49784_P050 | Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice. Oncoimmunology. 6, e1290035 (2017). 28405524 | 28405524 |
| 690 | DLL1 | ARP46625_P050 | Suprynowicz, F. A. et al. Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells. Proc. Natl. Acad. Sci. U. S. A. 109, 20035-40 (2012). 23169653 | 23169653 |
| 691 | DLL1 | ARP46625_P050 | Caliceti, C. et al. 17beta-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells. PLoS One 8, e71440 (2013). 23967210 | 23967210 |
| 692 | DLL3 | ARP47292_P050 | Expression of delta-like 3 is downregulated by aberrant DNA methylation and histone modification in hepatocellular carcinoma. Oncol Rep. 39, 2209-2216 (2018). 29512761 | 29512761 |
| 693 | DLX1 | ARP32866_P050 | Bökenkamp, R. et al. Dlx1 and Rgs5 in the ductus arteriosus: vessel-specific genes identified by transcriptional profiling of laser-capture microdissected endothelial and smooth muscle cells. PLoS One 9, e86892 (2014). 24489801 | 24489801 |
| 694 | DLX6 | ARP35763_P050 | Li, H. et al. Expression and function of Dlx genes in the osteoblast lineage. Dev. Biol. 316, 458-70 (2008). 18280462 | 18280462 |
| 695 | DMBT1 | ARP42352_P050 | Gonzalez-Gil, A et al. Isolation, identification and characterization of the human airway ligand for the eosinophil and mast cell immunoinhibitory receptor SIGLEC-8. J Allergy Clin Immunol. 2020 Aug 10; S0091-6749 (20) 31107-6. 32791164 | 32791164 |
| 696 | DMBT1 | OPPA01037 | Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis. Glycobiology 2021 8 31 1026-1036 33755113 | 33755113 |
| 697 | DMP-1 | ARP34602_P050 | Tooth Germ-Like Construct Transplantation for Whole-Tooth Regeneration: An In Vivo Study in the Miniature Pig. Artif Organs. 40, E39-50 (2016). 26582651 | 26582651 |
| 698 | DMRT1 | ARP30991_P050 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
| 699 | DnaK | OAED00201 | Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis. Nat Commun. 9, 866 (2018). 29491361 | 29491361 |
| 700 | DNASE1 | OKEH03902 | Degraded neutrophil extracellular traps promote the growth of Actinobacillus pleuropneumoniae. Cell Death Dis. 10, 657 (2019). 31506432 | 31506432 |
| 701 | DNASE1 | OKEH03902 | Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis. Int J Mol Sci. 21, NULL (2020). 32722502 | 32722502 |
| 702 | DNM1L | ARP52329_P050 | Su, Y. C., Chiu, H. W., Hung, J. C. & Hong, J. R. Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Apoptosis 19, 1457-70 (2014). 25008790 | 25008790 |
| 703 | DONSON | ARP45862_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 704 | DONSON | ARP45862_P050 | The GABAAα5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome. Neuroscience. 372, 192-212 (2018) 29292072 | 29292072 |
| 705 | DPF2 | ARP33221_P050 | Middeljans, E. et al. SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexes. PLoS One 7, e33834 (2012). 22442726 | 22442726 |
| 706 | DPF3 | ARP34293_P050 | Theodorou, M. et al. Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia. PLoS One 8, e76155 (2013). 24155890 | 24155890 |
| 707 | DPP10 | OAAB05596 | Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma. Dis Model Mech. 11, (2018). 29361513 | 29361513 |
| 708 | DPP4 | ARP63319_P050 | Upregulated expression and activation of membrane‑associated proteases in esophageal squamous cell carcinoma. Oncol Rep. 31, 2820-6 (2014). 24789592 | 24789592 |
| 709 | DPP6 | ARP44867_P050 | Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability. Acta Neuropathol. 137, 901-918 (2019). 30874922 | 30874922 |
| 710 | DR1 | ARP38085_T100 | Deng, W., Malecová, B., Oelgeschläger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). 19114554 | 19114554 |
| 711 | DRAM1 | ARP47432_P050 | Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils. Front Immunol. 11, 565545 (2020). 33262756 | 33262756 |
| 712 | DSCAM | ARP59932_P050 | DSCAM is differentially patterned along the optic axon pathway in the developing Xenopus visual system and guides axon termination at the target. Neural Dev 2022 1 17 5 35422013 | 35422013 |
| 713 | DSG2 | ARP45198_P050 | Hummitzsch, K. et al. A new model of development of the mammalian ovary and follicles. PLoS One 8, e55578 (2013). 23409002 | 23409002 |
| 714 | DTX1 | OAGA00965 | Glycogen synthase kinase 3β inhibition enhances Notch1 recycling. Mol Biol Cell. 29, 389-395 (2018). 29237816 | 29237816 |
| 715 | DTX1 | OAGA00965 | PI5P4Kγ functions in DTX1-mediated Notch signaling. Proc Natl Acad Sci U S A. 115, E1983-E1990 (2018). 29440432 | 29440432 |
| 716 | DYRK3 | ARP30647_P050 | Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling. EMBO Rep. 22, e51740 (2021). 33738926 | 33738926 |
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| 718 | E2F1 | P100821_P050 | Differential regulation of mammalian and avian ATOH1 by E2F1 and its implication for hair cell regeneration in the inner ear. Sci Rep. 11, 19368 (2021). 34588543 | 34588543 |
| 719 | E2F3 | ARP38089_P050 | Naga Prasad, S. V et al. Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J. Biol. Chem. 284, 27487-99 (2009). 19641226 | 19641226 |
| 720 | E2F3 | ARP38089_P050 | Melcher, R. et al. LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability. Carcinogenesis 32, 636-42 (2011). 21297112 | 21297112 |
| 721 | E2F3 | ARP38089_P050 | Giangreco, A. A. et al. Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue. Cancer Prev. Res. (Phila). 6, 483-94 (2013). 23503652 | 23503652 |
| 722 | EAAT2 | ARP33840_P050 | Pretto, D. I. et al. Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome. Neurobiol. Aging 35, 1189-97 (2014). 24332449 | 24332449 |
| 723 | EBF3 | ARP31837_T100 | Bennett, K. L., Romigh, T. & Eng, C. Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Res. 69, 9301-5 (2009). 19934318 | 19934318 |
| 724 | EBI3 | OKEH01925 | Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes. Int J Mol Sci 2021 23 22 NULL 34884474 | 34884474 |
| 725 | ECH1 | ARP43560_T100 | Xie, W.-D. et al. Enhanced peroxisomal beta-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice. Exp. Ther. Med. 2, 309-315 (2011). 22977503 | 22977503 |
| 726 | ECH1 | ARP43560_T100 | Xie, W., Zhang, S., Lei, F., Ouyang, X. & Du, L. Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression. Evid. Based. Complement. Alternat. Med. 2014, 903258 (2014). 25197313 | 25197313 |
| 727 | EDA | OAAB03423 | a de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia. BMC Genomics. 20, 715 (2019). 31533624 | 31533624 |
| 728 | EDEM1 | ARP50069_P050 | ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase. Histochem Cell Biol 2014 2 142 153-69 24664425 | 24664425 |
| 729 | EDF1 | ARP35695_P050 | Leidi, M., Mariotti, M. & Maier, J. A. M. Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis. Cell. Mol. Life Sci. 66, 2733-42 (2009). 19554257 | 19554257 |
| 730 | EDF1 | ARP35695_P050 | Leidi, M., Mariotti, M. & Maier, J. A. M. The effects of silencing EDF-1 in human endothelial cells. Atherosclerosis 211, 55-60 (2010). 20185128 | 20185128 |
| 731 | EDF1 | ARP35695_P050 | Leidi, M., Mariotti, M. & Maier, J. A. M. EDF-1 contributes to the regulation of nitric oxide release in VEGF-treated human endothelial cells. Eur. J. Cell Biol. 89, 654-60 (2010). 20605058 | 20605058 |
| 732 | EDF1 | ARP58983_P050 | Vitamin D Prevents High Glucose-Induced Lipid Droplets Accumulation in Cultured Endothelial Cells: The Role of Thioredoxin Interacting Protein. Biomedicines 2021 12 9 NULL 34944690 | 34944690 |
| 733 | EEA1 | ARP30074_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
| 734 | EED | ARP35697_P050 | Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2. BMC Cancer. 16, 583 (2016). 27485439 | 27485439 |
| 735 | EEF2 | ARP58457_P050 | Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2. Mol Cell. 74, 88-100.e9 (2019). 30876804 | 30876804 |
| 736 | EFEMP1 | ARP41342_P050 | Lutter, S., Xie, S., Tatin, F. & Makinen, T. Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation. J. Cell Biol. 197, 837-49 (2012). 22665518 | 22665518 |
| 737 | EFNB1 | ARP46450_P050 | Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome. J Proteome Res. 14, 3882-3891 (2015). 26267517 | 26267517 |
| 738 | EFNB3 | OAAF01784 | Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. Am J Physiol Heart Circ Physiol. 310, H861-72 (2016). 26851246 | 26851246 |
| 739 | EGLN2 | ARP34747_P050 | Gilbert, J. S., Banek, C. T., Bauer, A. J., Gingery, A. & Needham, K. Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. Hypertension 60, 1545-51 (2012). 23090773 | 23090773 |
| 740 | EGR1 | ARP32241_P050 | Barbolina, M. V, Adley, B. P., Ariztia, E. V, Liu, Y. & Stack, M. S. Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression. J. Biol. Chem. 282, 4924-31 (2007). 17158885 | 17158885 |
| 741 | EGR1 | ARP32241_P050 | Wenzel, K. et al. Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway. Biol. Chem. 388, 489-95 (2007). 17516844 | 17516844 |
| 742 | EGR1 | ARP32241_P050 | Jaluria, P., Konstantopoulos, K., Betenbaugh, M. & Shiloach, J. Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates. Biotechnol. Bioeng. 99, 1443-52 (2008). 18023050 | 18023050 |
| 743 | EGR1 | ARP32241_P050 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20368707 | 20368707 |
| 744 | EGR1 | ARP32241_P050 | Lane, K. R. et al. Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One 8, e58456 (2013). 23520512 | 23520512 |
| 745 | EGR1 | ARP32241_P050 | Ohata, Y. et al. Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice. J. Bone Miner. Res. 29, 1627-38 (2014). 24470103 | 24470103 |
| 746 | EGR1 | ARP32241_P050 | Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve. PLoS ONE. 11, e0153256 (2016). 27058953 | 27058953 |
| 747 | EGR2 | P100880_P050 | Latasa, M.-J., Ituero, M., Moran-Gonzalez, A., Aranda, A. & Cosgaya, J. M. Retinoic acid regulates myelin formation in the peripheral nervous system. Glia 58, 1451-64 (2010). 20648638 | 20648638 |
| 748 | EGR2 | P100880_P050 | Lagrange, B. et al. A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages. Biochim. Biophys. Acta 1833, 1936-46 (2013). 23602969 | 23602969 |
| 749 | EGR2 | P100880_P050 | Damm, F. et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov. 4, 1088-101 (2014). 24920063 | 24920063 |
| 750 | EHF | ARP40136_P050 | He, J. et al. Profile of Ets gene expression in human breast carcinoma. Cancer Biol. Ther. 6, 76-82 (2007). 17172821 | 17172821 |
| 751 | EIF2A | ARP41041_T100 | Xu, Y.-X., Liu, L., Caffaro, C. E. & Hirschberg, C. B. Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis. J. Biol. Chem. 285, 24600-8 (2010). 20529871 | 20529871 |
| 752 | EIF2AK4 | OABF01173 | Effects of the presence and absence of amino acids on translation, signaling, and long-term depression in hippocampal slices from Fmr1 knockout mice. J Neurochem. 151, 764-776 (2019). 31539452 | 31539452 |
| 753 | EIF2B5 | ARP61329_P050 | Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits. Biochem. J. 473, 571-80 (2016). 26614765 | 26614765 |
| 754 | EIF2B5 | ARP61329_P050 | Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs. Mol Biol Cell. 30, 942-958 (2019). 30726166 | 30726166 |
| 755 | EIF3M | ARP48293_T100 | Cheshenko, N., Trepanier, J. B., Segarra, T. J., Fuller, A. O. & Herold, B. C. HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target. PLoS One 5, e11829 (2010). 20676407 | 20676407 |
| 756 | EIF4A1 | ARP48065_P050 | Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediatetranslational response to energy stress. Elife. 6. pii: e21907 (2017). 28177284 | 28177284 |
| 757 | EIF4E3 | ARP41168_P050 | Yi, T., Papadopoulos, E., Hagner, P. R. & Wagner, G. Hypoxia-inducible factor-1a (HIF-1a) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J. Biol. Chem. 288, 18732-42 (2013). 23667251 | 23667251 |
| 758 | ELF3 | ARP36846_P050 | Namiki, T., Valencia, J. C., Hall, M. D. & Hearing, V. J. A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking. Anal. Biochem. 383, 265-9 (2008). 18801330 | 18801330 |
| 759 | ELOVL1 | ARP49759_P050 | Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration. J Biomed Sci. 25, 40 (2018). 29720183 | 29720183 |
| 760 | ELOVL6 | ARP64566_P050 | Transcriptional regulation of bovine elongation of very long chain fatty acids protein 6 in lipid metabolism and adipocyte proliferation.J Cell Biochem13932-139431208August2019 | 30945346 |
| 761 | EMC6 | ARP44679_P050 | The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection. Cell Rep. 27, 1666-1674.e4 (2019). 31067454 | 31067454 |
| 762 | EMC6 | OACA03845 | Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry. Nat Commun. 11, 1127 (2020). 32111841 | 32111841 |
| 763 | EMG1 | ARP40636_P050 | Armistead, J. et al. Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-39 (2009). 19463982 | 19463982 |
| 764 | EN1 | P100923_P050 | Beltran, A. S., Graves, L. M. & Blancafort, P. Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function. Oncogene. doi:10.1038/onc.2013.422 (2013). 24141779 | 24141779 |
| 765 | ENDOG | ARP52054_P050 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
| 766 | ENO1 | ARP34376_T100 | Rambaruth, N. D. S., Greenwell, P. & Dwek, M. V. The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer. Glycobiology 22, 839-48 (2012). 22322011 | 22322011 |
| 767 | ENO1 | ARP34377_P050 | Boraldi, F. et al. Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach. Biochim. Biophys. Acta 1774, 1402-13 (2007). 17904921 | 17904921 |
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| 769 | ENO1 | ARP34377_P050 | Deng, M. Y. et al. Frontal-subcortical protein expression following prenatal exposure to maternal inflammation. PLoS One 6, e16638 (2011). 21347362 | 21347362 |
| 770 | ENO1 | ARP34377_P050 | Kitahashi, T., Yoshimoto, M. & Imai, T. Novel immunohistochemical marker, integrin a(V)beta(3), for BOP-induced early lesions in hamster pancreatic ductal carcinogenesis. Oncol. Lett. 2, 229-234 (2011). 22866069 | 22866069 |
| 771 | ENO1 | ARP34377_P050 | Braceland, M. et al. Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. J. Fish Dis. doi:10.1111/jfd.12296 (2014). 25168106 | 25168106 |
| 772 | ENO2 | ARP60777_P050 | Choudhuri, A., Maitra, U. & Evans, T. Translation initiation factor eICC/IF3h targets specICC/IFic transcripts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. U. S. A. 110, 9818-23 (2013). 23716667 | 23716667 |
| 773 | ENO3 | ARP48203_T100 | Chaika, N. V et al. Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. PLoS One 7, e32996 (2012). 22412968 | 22412968 |
| 774 | ENPP1 | OAEB02445 | de la Croix Ndong, J. et al. Asfotase-a improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1. Nat. Med. 20, 904-10 (2014). 24997609 | 24997609 |
| 775 | ENTEROBACTER CLOACAE | OASA00656 | Antibiotic trapping by plasmid-encoded CMY-2 β-lactamase combined with reduced outer membrane permeability as a mechanism of carbapenem resistance in Escherichia coli. Antimicrob Agents Chemother. 57, 3941-9 (2013) 23733461 | 23733461 |
| 776 | ENTPD8 | ARP44815_P050 | Generation and Characterization of Specific Antibodies to the Murine and Human Ectonucleotidase NTPDase8. Front Pharmacol. 8, 115 (2017). 28337144 | 28337144 |
| 777 | EP300 | OAAF01891 | Differential Kat3 Usage Orchestrates the Integration of Cellular Metabolism with Differentiation. Cancers (Basel). 13 (2021). 34884992 | 34884992 |
| 778 | EPAS1 | ARP60108_P050 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J Physiol 2016 5 594 1327-40 26574162 | 26574162 |
| 779 | EPAS1 | ARP57040_P050 | HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice. Nat Commun 2020 1 11 4111 32807776 | 32807776 |
| 780 | EPB41L3 | OAGA01718 | Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules. Am J Respir Crit Care Med. 199, 1257-1266 (2019). 30422669 | 30422669 |
| 781 | EPHRIN B1 | OAAF00520 | Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine Phosphoproteome. J. Proteome Res. 14, 3882-91 (2015). 26267517 | 26267517 |
| 782 | ERAS | ARP55794_P050 | The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res. 16, 147 (2015). 26646719 | 26646719 |
| 783 | ERCC3 | ARP37963_P050 | A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. Cancer Discov. 6, 1267-1275 (2016). 27655433 | 27655433 |
| 784 | ERCC3 | ARP37963_P050 | Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer. Clin Cancer Res. NULL, NULL (2020) 33199492 | 33199492 |
| 785 | ERGIC2 | ARP34556_P050 | Nelson, T. J. & Alkon, D. L. Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid. J. Biol. Chem. 282, 31238-49 (2007). 17761669 | 17761669 |
| 786 | ERLIN2 | ARP58461_P050 | Zhang, Y. et al. Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells. Hum. Exp. Toxicol. 32, 797-806 (2013). 23338683 | 23338683 |
| 787 | ERP29 | ARP44820_P050 | Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation. Nat Commun. 8, 14151 (2017). 28218242 | 28218242 |
| 788 | ERVFRD-1 | ARP56008_P050 | OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A. 112, E6175-84 (2015). 26504231 | 26504231 |
| 789 | Esr2 | ARP33326_P050 | The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming. Nucleic Acids Res 2021 11 49 6144-6164 34096593 | 34096593 |
| 790 | ESRRG | ARP31655_T100 | Song, G. & Wang, L. Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma. Nucleic Acids Res. 36, 5727-35 (2008). 18776219 | 18776219 |
| 791 | ESRRG | ARP31655_T100 | Song, G. & Wang, L. A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals. PLoS One 4, e7829 (2009). 19946636 | 19946636 |
| 792 | Estradiol | OKCA00350 | Multi-Approach Assessment for Stress Evaluation in Rainbow Trout Females, Oncorhynchus mykiss (Walbaum, 1792) from Three Different Farms during the Summer Season. Animals (Basel) 2021 6 11 NULL 34204450 | 34204450 |
| 793 | ETS1 | P100604_T100 | ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase. Cancer Lett. 414, 190-204 (2018). 29174800 | 29174800 |
| 794 | ETS2 | OAAB06446 | Yoshimatsu, Y. et al. Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1. J. Cell Sci. 124, 2753-62 (2011). 21807940 | 21807940 |
| 795 | ETV4 | ARP32263_P050 | Hollenhorst, P. C., Paul, L., Ferris, M. W. & Graves, B. J. The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells. Genes Cancer 1, 1044-1052 (2011). 21373373 | 21373373 |
| 796 | ETV4 | ARP32263_P050 | Hollenhorst, P. C. et al. Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes Dev. 25, 2147-57 (2011). 22012618 | 22012618 |
| 797 | ETV4 | ARP32263_P050 | Selvaraj, N., Budka, J. A., Ferris, M. W., Jerde, T. J. & Hollenhorst, P. C. Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation. Mol. Cancer 13, 61 (2014). 24642271 | 24642271 |
| 798 | ETV4 | ARP32263_P050 | An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. Cell Rep. 17, 1289-1301 (2016). 27783944 | 27783944 |
| 799 | ETV4 | ARP32263_P050 | Inactivation of Capicua drives cancer metastasis. Nat. Genet. 49, 87-96 (2017). 27869830 | 27869830 |
| 800 | ETV4 | ARP32263_P050 | Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells. Sci Rep. 7, 1166 (2017). 28446749 | 28446749 |
| 801 | ETV4 | ARP32263_P050 | ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis. Cancer Res. 78, 1972-1985 (2018). 29654155 | 29654155 |
| 802 | ETV4 | ARP32263_P050 | Interaction of BRAF-induced ETS factors with mutant TERT promoter in papillary thyroid cancer. Endocr Relat Cancer. 26, 629-641 (2019). 30999281 | 30999281 |
| 803 | ETV4 | ARP32263_P050 | Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nat Commun. 10, 2000 (2019). 31043608 | 31043608 |
| 804 | ETV4 | ARP32263_P050 | ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells. Cancer Res. 80, 1234-1245 (2020). 32046982 | 32046982 |
| 805 | EXT2 | ARP44277_P050 | Oocyte Cytoplasmic Gas6 and Heparan Sulfate (HS) are Required to Establish the Open Chromatin State in Nuclei During Remodeling and Reprogramming. Cell Physiol Biochem. 45, 37-53 (2018). 29316553 | 29316553 |
| 806 | EYA1 | ARP32434_P050 | The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 33, 22-35 (2015). 25816987 | 25816987 |
| 807 | F13A1 | OKEH02738 | A comparative proteomic study of plasma in Colombian childhood acute lymphoblastic leukemia. PLoS One. 14, e0221509 (2019). 31437251 | 31437251 |
| 808 | F2 | ARP35205_P050 | Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling. Am J Pathol 2022 2 192 361-378 35144762 | 35144762 |
| 809 | FA2H | ARP33121_P050 | Characterization of the endocannabinoid system in subcutaneous adipose tissue in periparturient dairy cows and its association to metabolic profiles. PLoS One. 13, e0205996 (2018). 30403679 | 30403679 |
| 810 | FA2H | ARP33121_P050 | Phosphoproteomic Analysis of Subcutaneous and Omental Adipose Tissue Reveals Increased Lipid Turnover in Dairy Cows Supplemented with Conjugated Linoleic Acid. Int J Mol Sci. 22 (2021). 33810070 | 33810070 |
| 811 | Fa2h | ARP33121_P050 | Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows.Animals (Basel)NULL126March2022 | 35327191 |
| 812 | FABP2 | OKCD06490 | Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability. Am J Pathol. 187, 2686-2697 (2017) 28935573 | 28935573 |
| 813 | FABP3 | ARP33823_T100 | Chen, H.-M., Zheng, C.-X., Gao, Q., Ge, Y.-C. & Liu, Z.-H. Heart-type fatty acid binding protein is associated with proteinuria in obesity. PLoS One 7, e45691 (2012). 23029183 | 23029183 |
| 814 | FABP3 | OKEH00897 | Impaired Relaxation and Reduced Lusitropic Reserve in Atrial Myocardium in the Obese Patients. Front Cardiovasc Med. 8, 739907 (2021). 34778401 | 34778401 |
| 815 | FABP7 | ARP33827_T100 | Sun, Y. et al. A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain. J. Proteomics 74, 547-57 (2011). 21262400 | 21262400 |
| 816 | FAH | ARP41681_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 817 | FAH | ARP41681_T100 | Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model. J. Biol. Chem. 290, 23173-87 (2015). 26224633 | 26224633 |
| 818 | FAM123B | OAAB03558 | Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer. Clin Cancer Res. 21, 4709-18 (2015). 26071483 | 26071483 |
| 819 | FAM20A | OACD03385 | Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome. Front Cell Dev Biol. 8, 605084 (2021). 33425910 | 33425910 |
| 820 | FAM20A | OACD03385 | Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach. Front Endocrinol (Lausanne). 12, 752568 (2021). 34777248 | 34777248 |
| 821 | FAM20A | OACD03385 | Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view.Front Physiol95711013NULLSeptember2022 | 36091358 |
| 822 | FAM20C | OAAB01003 | Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome. Front Cell Dev Biol. 8, 605084 (2021). 33425910 | 33425910 |
| 823 | FAM20C | OAAB01003 | Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view.Front Physiol95711013NULLSeptember2022 | 36091358 |
| 824 | FAM222A | ARP69038_P050 | FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease. Nat Commun. 11, 411 (2020). 31964863 | 31964863 |
| 825 | FAM40B | OAAF04756 | Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKCγ Activity and Regulates Purkinje Cell Dendritic Growth. Mol Neurobiol 2016 8 53 5149-60 26399641 | 26399641 |
| 826 | FAM83F | ARP52602_P050 | The Highly Expressed FAM83F Protein in Papillary Thyroid Cancer Exerts a Pro-Oncogenic Role in Thyroid Follicular Cells. Front Endocrinol (Lausanne). 10, 134 (2019). 30881348 | 30881348 |
| 827 | FAM98A | ARP55265_P050 | Erratum to: FAM98A is a novel substrate of PRMT1 required for tumor cell migration, invasion and colony formation. Tumour Biol. 37, 7001 (2016). 26825979 | 26825979 |
| 828 | FAM98A | ARP55265_P050 | FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression. Int. J. Biochem. Cell Biol. 84, 1-13 (2017). 28040436 | 28040436 |
| 829 | FASTK | OAAB08734 | Bauer, A. et al. Identification of malignancy factors by analyzing cystic tumors of the pancreas. Pancreatology 9, 34-44 (2009). 19077453 | 19077453 |
| 830 | FBL | ARP40366_T100 | Ernoult-Lange, M. et al. Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies. Mol. Biol. Cell 20, 176-87 (2009). 18923137 | 18923137 |
| 831 | FBL | ARP40366_T100 | Armistead, J. et al. Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-39 (2009). 19463982 | 19463982 |
| 832 | FBP1 | ARP41406_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 833 | FBXL13 | OAAB12542 | FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. EMBO Rep. 19, (2018). 29348145 | 29348145 |
| 834 | FBXL2 | OAAB02444 | Crystal structure and interaction studies of the human FBxo3 ApaG domain. FEBS J. 283, 2091-101 (2016). 27010866 | 27010866 |
| 835 | FBXO7 | ARP43128_P050 | The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy. Nat Neurosci. 16, 1257-65 (2013). 23933751 | 23933751 |
| 836 | FBXO7 | ARP43128_P050 | Chemical inhibition of FBXO7 reduces inflammation and confers neuroprotection by stabilizing the mitochondrial kinase PINK1. JCI Insight. 5, (2020). 32493843 | 32493843 |
| 837 | FBXO7 | ARP38941_T100 | The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway. Biochim Biophys Acta Gen Subj 2021 1 1865 129754 33010352 | 33010352 |
| 838 | FBXW2 | ARP43109_P050 | Van Rechem, C. et al. The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein. J. Biol. Chem. 286, 30462-70 (2011). 21757720 | 21757720 |
| 839 | Fbxw7 | ARP37443_P050 | Huang, H. et al. NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression. Oncotarget 5, 493-505 (2014). 24457827 | 24457827 |
| 840 | FBXW7 | ARP47419_P050 | Gong, Y. et al. Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat. Genet. 46, 588-94 (2014). 24793136 | 24793136 |
| 841 | FBXW7 | ARP47419_P050 | FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation. Mol Med Rep. 23 (2021). 33537812 | 33537812 |
| 842 | FBXW8 | ARP55585_P050 | Lin, P. et al. Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells. Mol. Biol. Rep. 38, 1741-7 (2011). 20878477 | 20878477 |
| 843 | FECH | ARP41682_T100 | Miyake, M. et al. siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines. Photochem. Photobiol. 85, 1020-7 19320847 | 19320847 |
| 844 | FECH | ARP41682_T100 | Susceptibility to 5-aminolevulinic acid based photodynamic therapy in WHO I meningioma cells corresponds to ferrochelatase activity.Photochem Photobiol235-41871November2010 | 21073472 |
| 845 | FGA | ARP41759_P050 | Prieto-García, A. et al. Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen. J. Biol. Chem. 287, 7834-44 (2012). 22235124 | 22235124 |
| 846 | FGA | ARP41759_P050 | Matsumoto, M. et al. An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line. Hepatol. Res. (2014). doi:10.1111/hepr.12353 24802089 | 24802089 |
| 847 | FGD1 | ARP38472_P050 | Zou, W. et al. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. J. Clin. Invest. 121, 4383-92 (2011). 21965325 | 21965325 |
| 848 | FGF2 | ARP42005_P050 | MicroRNA-205 mediates endothelial progenitor functions in distraction osteogenesis by targeting the transcription regulator NOTCH2. Stem Cell Res Ther. 12, 101 (2021). 33536058 | 33536058 |
| 849 | FGF2 | | The garlic-derived organosulfur compound diallyl trisulphide suppresses tissue factor function. Food Funct 2022 3 13 1246-1255 35022635 | 35022635 |
| 850 | FGF22 | OAAF02973 | Fibroblast growth factor 22 is a novel modulator of depression through interleukin-1β. CNS Neurosci Ther. 23, 907-916 (2017). 28948716 | 28948716 |
| 851 | FGF22 | OKEH02513 | Xu, Y. et al. Fibroblast growth factor 22 is a novel modulator of depression through interleukin‐1β. CNS Neurosci Ther. 2017 Nov; 23(11): 907-916. 28948716 | 28948716 |
| 852 | FGFR1 | OAAB11171 | Oncogenic fusion protein BCR-FGFR1 requires the breakpoint cluster region-mediated oligomerization and chaperonin Hsp90 for activation. Haematologica. 105, 1262-1273 (2020). 31439673 | 31439673 |
| 853 | FGFR1 | OKEH00124 | Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease. Diagnostics (Basel). 8, (2018). 30297602 | 30297602 |
| 854 | FGFR3 | OAAB11172 | Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling. Oncotarget. 9, 34306-34319 (2018). 30344944 | 30344944 |
| 855 | FGFR4 | OKDD00266 | Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease. Diagnostics (Basel). 8, (2018). 30297602 | 30297602 |
| 856 | FGFR4 | OKDD00266 | Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma. Clin Transl Gastroenterol. 11, e00179 (2020). 32677805 | 32677805 |
| 857 | FGL2 | ARP52235_P050 | Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Transplantation. 100, 1871-9 (2016). 27077599 | 27077599 |
| 858 | FGL2 | ARP52235_P050 | Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function. Basic Res. Cardiol. 112, 20 (2017). 28258298 | 28258298 |
| 859 | FHL1 | ARP34378_T100 | Windpassinger, C. et al. An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1. Am. J. Hum. Genet. 82, 88-99 (2008). 18179888 | 18179888 |
| 860 | FHL1 | ARP34378_T100 | Quinzii, C. M. et al. X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1. Am. J. Hum. Genet. 82, 208-13 (2008). 18179901 | 18179901 |
| 861 | FHL1 | ARP34378_T100 | Schoser, B. et al. Consequences of mutations within the C terminus of the FHL1 gene. Neurology 73, 543-51 (2009). 19687455 | 19687455 |
| 862 | FHL1 | ARP34378_T100 | Gueneau, L. et al. Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy. Am. J. Hum. Genet. 85, 338-53 (2009). 19716112 | 19716112 |
| 863 | FHL1 | ARP34378_T100 | Sharma, P., Shathasivam, T., Ignatchenko, V., Kislinger, T. & Gramolini, A. O. Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis. Mol. Biosyst. 7, 1185-96 (2011). 21246116 | 21246116 |
| 864 | FHL1 | ARP34378_T100 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22053194 | 22053194 |
| 865 | FHL1 | ARP34378_T100 | Koike, K. et al. High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer. Int. J. Oncol. 42, 141-50 (2013). 23123766 | 23123766 |
| 866 | FHL1 | ARP34378_T100 | Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Hum Mol Genet. 23, 209-25 (2014). 23975679 | 23975679 |
| 867 | FHL1 | ARP34378_T100 | Fujii, T. et al. A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles. J. Neurol. Sci. 343, 206-10 (2014). 24928078 | 24928078 |
| 868 | FHL1 | ARP34378_T100 | Fhl1 W122S causes loss of protein function and late-onset mild myopathy. Hum Mol Genet. 24, 714-26 (2015). 25274776 | 25274776 |
| 869 | FHL1 | ARP34378_T100 | Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death. Circ Cardiovasc Genet. 9, 130-5 (2016). 26933038 | 26933038 |
| 870 | FHL1 | ARP34378_T100 | Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology. Neuromuscul. Disord. 27, 338-351 (2017). 28214269 | 28214269 |
| 871 | FHL1 | ARP34378_T100 | Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice. Hum Mol Genet. 28, 209-219 (2019). 30260394 | 30260394 |
| 872 | FHL2 | ARP34506_T100 | Han, W. et al. FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells. Nucleic Acids Res. 37, 3996-4009 (2009). 19417068 | 19417068 |
| 873 | FHL2 | ARP34506_T100 | Saeki, Y. et al. Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells. BMC Genomics 10, 545 (2009). 19925682 | 19925682 |
| 874 | FJX1 | ARP47013_P050 | Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma. PLoS ONE. 10, e0130464 (2015). 26536470 | 26536470 |
| 875 | FJX1 | ARP47013_P050 | In vitro evaluation of dual-antigenic PV1 peptide vaccine in head and neck cancer patients. Hum Vaccin Immunother. 15, 167-178 (2018). 30193086 | 30193086 |
| 876 | FKBP5 | OKEH00685 | Glucocorticoid receptor mutations and clinical sensitivity to glucocorticoid in Chinese multiple sclerosis patients. Neurol Sci. 41, 2767-2771 (2020). 32277392 | 32277392 |
| 877 | FLAG | OAEA00002 | Association of clinical severity with FANCB variant type in Fanconi anemia. Blood. 135, 1588-1602 (2020). 32106311 | 32106311 |
| 878 | FLI1 | ARP38096_T100 | Bujor, A. M. et al. Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1. Int. J. Mol. Med. 30, 1473-80 (2012). 23041765 | 23041765 |
| 879 | FLNC | ARP64454_P050 | FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. JACC Basic Transl Sci. 1, 344-359 (2016). 28008423 | 28008423 |
| 880 | FLOT1 | ARP65758_P050 | Dietary Fatty Acids Affect Red Blood Cell Membrane Composition and Red Blood Cell ATP Release in Dairy Cows. Int J Mol Sci. 20, (2019). 31195708 | 31195708 |
| 881 | FLOT1 | OKEH02189 | Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer. BMC Cancer. 21, 315 (2021) 33761899 | 33761899 |
| 882 | FMO3 | ARP43012_P050 | Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved? Pharmacol Res 2021 NULL 163 105273 33197599 | 33197599 |
| 883 | FMR1 | OAEB01228 | Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies. PLoS Genet. 9, e1003890 (2013). 24204304 | 24204304 |
| 884 | FOLH1 | ARP44691_P050 | Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry. PLoS One. 12, e0176958 (2017). 28472168 | 28472168 |
| 885 | FOLH1 | OAAB10007 | Walder, K. K. et al. Immunohistological and electrophysiological evidence that N-acetylaspartylglutamate is a co-transmitter at the vertebrate neuromuscular junction. Eur. J. Neurosci. 37, 118-29 (2013). 23134476 | 23134476 |
| 886 | Folic acid | OKEH02550 | Folic acid supplementation improves vascular endothelial function, yet not skin blood flow during exercise in the heat, in patients with heart failure. Am J Physiol Regul Integr Comp Physiol. 315, R810-R819 (2018). 29975566 | 29975566 |
| 887 | FOLR1 | ARP41427_P050 | Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation. Nat Commun. 12, 3362 (2021). 34099692 | 34099692 |
| 888 | FOSL1 | ARP31377_P050 | Yang, L. et al. Biological function and prognostic significance of peroxisome proliferator-activated receptor d in rectal cancer. Clin. Cancer Res. 17, 3760-70 (2011). 21499227 | 21499227 |
| 889 | FOSL1 | ARP31377_P050 | Seitz, O., Schürmann, C., Pfeilschifter, J., Frank, S. & Sader, R. Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes. J. Craniomaxillofac. Surg. 40, 379-86 (2012). 21840727 | 21840727 |
| 890 | FOXA1 | ARP38479_P050 | Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). 22959654 | 22959654 |
| 891 | FOXA2 | ARP31944_P050 | Richards, T. J. et al. Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 302, L746-54 (2012). 22268124 | 22268124 |
| 892 | FOXA2 | ARP31944_P050 | Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). 22959654 | 22959654 |
| 893 | FOXA2 | ARP31944_P050 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
| 894 | FOXA3 | ARP31945_P050 | Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). 22959654 | 22959654 |
| 895 | FOXC1 | ARP32300_T100 | Potential for transcriptional upregulation of cochlin in glaucomatous trabecular meshwork: a combinatorial bioinformatic and biochemical analytical approach. Invest Ophthalmol Vis Sci. 50, 3106-11 (2009). 19098315 | 19098315 |
| 896 | FOXD1 | OAAB10686 | FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness. Cancers (Basel). 11, (2019). 31795213 | 31795213 |
| 897 | FOXF1 | ARP32296_T100 | Lo, P.-K. et al. Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas. Exp. Mol. Pathol. 94, 262-9 (2013). 23103611 | 23103611 |
| 898 | FOXF1 | ARP32296_T100 | Tamura, M. et al. Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness. Oncogene (2013). doi:10.1038/onc.2013.427 24186199 | 24186199 |
| 899 | FOXF2 | ARP31694_T100 | The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression. Cell. Signal. 28, 1502-19 (2016). 27377963 | 27377963 |
| 900 | FOXK2 | ARP34775_P050 | Komorek, J. et al. Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J. Virol. 84, 2719-31 (2010). 20053746 | 20053746 |
| 901 | Foxl2 | ARP39552_P050 | The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming. Nucleic Acids Res 2021 11 49 6144-6164 34096593 | 34096593 |
| 902 | FOXM1 | ARP39518_P050 | Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury. e04028 (2020). 32577545 | 32577545 |
| 903 | FOXM1 | ARP39519_P050 | Hu, C. et al. LXRa-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells. Oncogene (2013). doi:10.1038/onc.2013.250 23812424 | 23812424 |
| 904 | FOXO1 | ARP38094_T100 | Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell. 8, 726-37 (2009). 19780720 | 19780720 |
| 905 | FOXO1 | ARP38094_T100 | Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 17, 507-17 (2014). 25298234 | 25298234 |
| 906 | FOXO1A | ARP38094_T100 | Hsu, C.-Y. & Hu, T.-H. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15, 389-400 (2014). 24973265 | 24973265 |
| 907 | FOXO3 | ARP70642_P050 | Foxo3a aggravates inflammation and induces apoptosis in IL-1-treated rabbit chondrocytes via positively regulating tenascin-c. Folia Histochem Cytobiol 2020 1 58 1-8 32003441 | 32003441 |
| 908 | FOXP1 | ARP32564_T100 | Jepsen, K., Gleiberman, A. S., Shi, C., Simon, D. I. & Rosenfeld, M. G. Cooperative regulation in development by SMRT and FOXP1. Genes Dev. 22, 740-5 (2008). 18347093 | 18347093 |
| 909 | FOXP1 | ARP32564_T100 | Konstantoulas, C. J., Parmar, M. & Li, M. FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. J. Neurochem. 113, 836-47 (2010). 20175877 | 20175877 |
| 910 | FOXP1 | ARP32564_T100 | Tang, B. et al. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease. Hum. Mol. Genet. 21, 3097-111 (2012). 22492998 | 22492998 |
| 911 | FOXP3 | ARP32743_T100 | Kawabata, A. et al. Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses. Cytotherapy 15, 586-97 (2013). 23474329 | 23474329 |
| 912 | FOXP3 | OAAB01500 | NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal. Oncotarget. 7, 2475-95 (2016). 26673617 | 26673617 |
| 913 | FOXQ1 | ARP39754_T100 | Potential for transcriptional upregulation of cochlin in glaucomatous trabecular meshwork: a combinatorial bioinformatic and biochemical analytical approach. Invest Ophthalmol Vis Sci. 50, 3106-11 (2009). 19098315 | 19098315 |
| 914 | FPGS | ARP63438_P050 | A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer. Lung Cancer. 102, 15-20 (2016). 27987582 | 27987582 |
| 915 | FPR2 | OKEH01364 | Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal Transition. Cells. 9, (2020). 32290034 | 32290034 |
| 916 | Free Tri-iodothyronine | OKCA00138 | A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action. Thyroid 2020 8 30 1193-1204 32122258 | 32122258 |
| 917 | Free-Thyroxine 4 | OKCA00139 | A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action. Thyroid 2020 8 30 1193-1204 32122258 | 32122258 |
| 918 | FTCD | ARP41577_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 919 | FTH1 | ARP54620_P050 | Potrykus, J. et al. Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events. PLoS Pathog. 9, e1003676 (2013). 24146619 | 24146619 |
| 920 | FUBP1 | ARP35704_P050 | Milosevic, J., Bulau, P., Mortz, E. & Eickelberg, O. Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates. Proteomics 9, 1230-40 (2009). 19253281 | 19253281 |
| 921 | FUBP1 | ARP37732_T100 | Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. J. Am. Soc. Nephrol. 27, 2645-57 (2016). 26839368 | 26839368 |
| 922 | FUNDC1 | ARP53280_P050 | Huang, M. L.-H. et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2a phosphorylation, and the induction of downstream targets. Am. J. Pathol. 183, 745-57 (2013). 23886890 | 23886890 |
| 923 | FUNDC1 | ARP53280_P050 | MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J Biol Chem. 289, 10691-701 (2014). 24573672 | 24573672 |
| 924 | FUNDC1 | ARP53280_P050 | Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett. 589, 1847-54 (2015). 25980607 | 25980607 |
| 925 | FUNDC1 | ARP53280_P050 | FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions. EMBO J. 35, 1368-84 (2016). 27145933 | 27145933 |
| 926 | FUNDC1 | ARP53280_P050 | Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy. Autophagy. 12, 2363-2373 (2016). 27653272 | 27653272 |
| 927 | FUNDC1 | ARP53280_P050 | Spermidine preconditioning ameliorates laurate-induced brain injury by maintaining mitochondrial stability. Neurol. Res. 39, 248-258 (2017). 28112032 | 28112032 |
| 928 | FUNDC1 | ARP53280_P050 | Mark A Lampert, et al. BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation. 1182-1198 (2019). 30741592 | 30741592 |
| 929 | FUNDC1 | ARP53280_P050 | STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Nat Commun. 10, 2059 (2019). 31053718 | 31053718 |
| 930 | FUNDC1 | ARP53280_P050 | BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation. Autophagy. 42370 (2020). 33044904 | 33044904 |
| 931 | FUNDC1 | ARP53280_P050 | Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation. Redox Biol. 46, 102038 (2021) 34416478 | 34416478 |
| 932 | FUNDC1 | ARP63297_P050 | FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis. Nat Commun 2021 1 12 2616 33972548 | 33972548 |
| 933 | FUR | OKCD04268 | Pulmonary, cardiac and renal distribution of ACE2, furin, TMPRSS2 and ADAM17 in rats with heart failure: Potential implication for COVID-19 disease. J Cell Mol Med 2021 8 25 3840-3855 33660945 | 33660945 |
| 934 | FUT1 | ARP44222_P050 | Molecular clock regulates daily a1-2-fucosylation of the neural cell adhesion molecule (NCAM) within mouse secondary olfactory neurons. J Biol Chem. 289, 36158-65 (2014). 25384980 | 25384980 |
| 935 | FXR | ARP45626_P050 | Yamada, T. et al. Guggulsterone suppresses bile acid-induced and constitutive caudal-related homeobox 2 expression in gut-derived adenocarcinoma cells. Anticancer Res. 30, 1953-60 (2010). 20651339 | 20651339 |
| 936 | FZD10 | ARP41262_P050 | Gonzalez, P., Fernandez-Martos, C. M., Gonzalez-Fernandez, C., Arenas, E. & Rodriguez, F. J. Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. PLoS One 7, e50793 (2012). 23251385 | 23251385 |
| 937 | FZD4 | ARP41266_P050 | McIver, S. C. et al. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS One 7, e35553 (2012). 22536405 | 22536405 |
| 938 | FZD4 | ARP41266_P050 | Gonzalez, P., Fernandez-Martos, C. M., Gonzalez-Fernandez, C., Arenas, E. & Rodriguez, F. J. Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats. PLoS One 7, e50793 (2012). 23251385 | 23251385 |
| 939 | FZD4 | ARP41266_P050 | Wang, L. et al. Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae. PLoS One 8, e56025 (2013). 23405249 | 23405249 |
| 940 | FZD7 | ARP41251_P050 | Ueno, K. et al. Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia 10, 697-705 (2008). 18592008 | 18592008 |
| 941 | FZD7 | ARP41251_P050 | Gökmen-Polar, Y. et al. Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer. Breast Cancer Res. Treat. 127, 375-84 (2011). 20602165 | 20602165 |
| 942 | FZD7 | ARP41251_P050 | Ohba, S., Lanigan, T. M. & Roessler, B. J. Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes. Osteoarthritis Cartilage 18, 1620-9 (2010). 20868760 | 20868760 |
| 943 | FZD7 | ARP41251_P050 | Schmuck, R. et al. Genotypic and phenotypic characterization of side population of gastric cancer cell lines. Am. J. Pathol. 178, 1792-804 (2011). 21435459 | 21435459 |
| 944 | FZD7 | ARP41251_P050 | McIver, S. C. et al. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS One 7, e35553 (2012). 22536405 | 22536405 |
| 945 | FZD8 | ARP41283_P050 | MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8. Oncotarget. 7, 40644-40656 (2016). 27276676 | 27276676 |
| 946 | FZD8 | OAEB02431 | Yin, S. et al. Tumor-initiating cells and FZD8 play a major role in drug resistance in triple-negative breast cancer. Mol. Cancer Ther. 12, 491-8 (2013). 23445611 | 23445611 |
| 947 | FZD9 | ARP41253_T100 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20234818 | 20234818 |
| 948 | FZR1 | ARP51279_P050 | Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats. Mol Pain. 12, (2016). 27184142 | 27184142 |
| 949 | G3BP | ARP37713_T100 | Coxsackievirus counters the host innate immune response by blocking type III interferon expression. J. Gen. Virol. 97, 1-12 (2016). 26935471 | 26935471 |
| 950 | G3BP1 | ARP37713_T100 | Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication. J Virol. 89, 4457-69 (2015). 25653451 | 25653451 |
| 951 | G3BP1 | ARP37713_T100 | Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication. Open Biol. 6, (2016). 27383630 | 27383630 |
| 952 | G3BP1 | ARP37713_T100 | Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation. J Virol. 93, (2019). 30404792 | 30404792 |
| 953 | G3BP1 | ARP37713_T100 | Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response. Mol Cell. 73, 946-958.e7 (2019). 30661979 | 30661979 |
| 954 | G3BP1 | ARP70642_P050 | Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways. Cell Rep 2022 4 39 110736 35476995 | 35476995 |
| 955 | G6PC | ARP44223_P050 | Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). 26882989 | 26882989 |
| 956 | G6PC | ARP44223_P050 | Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). 28218919 | 28218919 |
| 957 | G6PC | ARP44224_P050 | Iwasa, M. et al. Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis. PLoS One 8, e70309 (2013). 23936183 | 23936183 |
| 958 | G6pc | ARP36992_P050 | The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes. Nat Commun 2022 1 13 1052 35217669 | 35217669 |
| 959 | GABA | OKEH02564 | Alejandra Romo-Araiza, Gabriela Gutiérrez-Salmeán, Emilio J. Galván, Melissa Hernández-Frausto, Gabriel Herrera-López, Hector Romo-Parra, Valentina García-Contreras, Ana María Fernández-Presas, Ricardo Jasso-Chávez, Cesar V. Borlongan, & Antonio Ibarra1. Probiotics and Prebiotics as a Therapeutic Strategy to Improve Memory in a Model of Middle-Aged Rats. Front Aging Neurosci. 10, 416 (2018). PMC6305305 | PMC6305305 |
| 960 | GABA | OKEH02564 | Neurobehavioral effects of acute low-dose whole-body irradiation. J Radiat Res. 62, 804-811 (2021). 33982114 | 33982114 |
| 961 | GABRA2 | AVARP13026_T100 | Kitayama, T. et al. Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice. Mol. Pain 9, 23 (2013). 23639135 | 23639135 |
| 962 | GABRA5 | ARP30687_P050 | a5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. Acta Neuropathol. 127, 593-603 (2014). 24196163 | 24196163 |
| 963 | GABRA5 | ARP34984_P050 | Extrasynaptic α5GABAA receptors on proprioceptive afferents produce a tonic depolarization that modulates sodium channel function in the rat spinal cord. J Neurophysiol. 120, 2953-2974 (2018). 30256739 | 30256739 |
| 964 | GABRE | ARP35342_P050 | Hengen, K. B., Gomez, T. M., Stang, K. M., Johnson, S. M. & Behan, M. Changes in ventral respiratory column GABAaR e- and d-subunits during hibernation mediate resistance to depression by EtOH and pentobarbital. Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R272-83 (2011). 21084677 | 21084677 |
| 965 | GABRE | ARP35342_P050 | Hengen, K. B. et al. Increased GABA(A) receptor e-subunit expression on ventral respiratory column neurons protects breathing during pregnancy. PLoS One 7, e30608 (2012). 22303446 | 22303446 |
| 966 | GABRE | ARP35342_P050 | Fatemi, S. H., Folsom, T. D., Rooney, R. J. & Thuras, P. D. Expression of GABAA a2-, beta1- and e-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl. Psychiatry 3, e303 (2013). 24022508 | 24022508 |
| 967 | GABRG2 | OAEB01374 | Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex. Mol Pain. 14, 1744806918783470 (2018). 29956582 | 29956582 |
| 968 | GABRP | AVARP13034_P050 | Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast. Mol Hum Reprod. 26, 425-440 (2020) 32359161 | 32359161 |
| 969 | GABRQ | ARP35283_P050 | Fatemi, S. H., Folsom, T. D., Rooney, R. J. & Thuras, P. D. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl. Psychiatry 3, e271 (2013). 23778581 | 23778581 |
| 970 | GABRR2 | ARP35060_P050 | Fatemi, S. H., Folsom, T. D., Rooney, R. J. & Thuras, P. D. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl. Psychiatry 3, e271 (2013). 23778581 | 23778581 |
| 971 | GADD45B | ARP48346_P050 | Babu, E. et al. Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene 30, 4026-37 (2011). 21505039 | 21505039 |
| 972 | GADD45B | ARP48346_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22048458 | 22048458 |
| 973 | GADD45B | ARP48346_P050 | Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. Alcohol. Clin. Exp. Res. 40, 263-72 (2016). 26842245 | 26842245 |
| 974 | GADD45B | ARP48346_P050 | BDNF rs6265 methylation and genotype interact on risk for schizophrenia. Epigenetics. 11, 11-23 (2016). 26889735 | 26889735 |
| 975 | GADD45B | ARP48346_P050 | ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b. Cell Death Dis. 10, 360 (2019). 31043581 | 31043581 |
| 976 | GAGE12B | OAAB07499 | Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 12, 7142 (2021). 34880251 | 34880251 |
| 977 | GALR2 | OABF00517 | Spexin Acts as Novel Regulator for Bile Acid Synthesis. Front Physiol. 9, 378 (2018). 29692737 | 29692737 |
| 978 | GALR3 | OAAF04899 | Spexin Acts as Novel Regulator for Bile Acid Synthesis. Front Physiol. 9, 378 (2018). 29692737 | 29692737 |
| 979 | GAPDH | ARP40175_P050 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
| 980 | GAPDH | ARP40175_P050 | Kalinec, G. M. et al. Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways. Hear. Res. 313, 26-37 (2014). 24793116 | 24793116 |
| 981 | GAPDH | OAAD00231 | Kam, A. et al. Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities. Int. J. Cardiol. 171, 231-42 (2014). 24388544 | 24388544 |
| 982 | GAPDH | OAAD00231 | Expression of Kruppel-like factor 8 and Ki67 in lung adenocarcinoma and prognosis. Exp Ther Med. 14, 1351-1356 (2017). 28810596 | 28810596 |
| 983 | GAPDH | OAAJ03302 | Differential Abundance of Brain Mitochondrial Proteins in Yak and Cattle: A Proteomics-Based Study. Front Vet Sci. 8, 663031 (2021) 34532350 | 34532350 |
| 984 | GAPDH | OAEA00006 | Pannunzio, N. R. et al. Rad59 regulates association of Rad52 with DNA double-strand breaks. Microbiologyopen 1, 285-97 (2012). 23170228 | 23170228 |
| 985 | GAPDH | OAEA00006 | Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia. J. Biol. Chem. 290, 23264-81 (2015). 26242736 | 26242736 |
| 986 | GAPDH | OAEA00006 | CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis. Oncotarget. 6, 28588-606 (2015). 26396175 | 26396175 |
| 987 | GAPDH | OAEA00006 | HEI-OC1 cells as a model for investigating drug cytotoxicity. Hear. Res. 335, 105-17 (2016). 26930622 | 26930622 |
| 988 | GAPDH | OAEA00006 | MEK inhibitors as a novel therapy for neuroblastoma: Their in vitro effects and predicting their efficacy. J. Pediatr. Surg. 51, 2074-2079 (2016). 27686482 | 27686482 |
| 989 | GAPDH | OAEA00006 | Homologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair. Nucleic Acids Res. 45, 1879-1888 (2017). 27923995 | 27923995 |
| 990 | GAPDH | OAEA00006 | CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells. Int. J. Oncol. 50, 329-336 (2017). 27959393 | 27959393 |
| 991 | GAPDH | OAPA00361 | Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients. Cell Death Dis. 12, 797 (2021) 34404763 | 34404763 |
| 992 | GAPDH | OASA03787 | The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959 | 27618959 |
| 993 | GATA2 | ARP31855_T100 | Mammoto, A. et al. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature 457, 1103-8 (2009). 19242469 | 19242469 |
| 994 | GATA2 | ARP31855_T100 | Huang, Y.-J. et al. The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer. Mutat. Res. 702, 32-9 (2010). 20599521 | 20599521 |
| 995 | GATA2 | ARP31855_T100 | Jack, B. H. A. & Crossley, M. GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J. Biol. Chem. 285, 32405-14 (2010). 20705609 | 20705609 |
| 996 | GATA2 | ARP31855_T100 | Fujiwara, T. et al. Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells. PLoS One 7, e40959 (2012). 23028422 | 23028422 |
| 997 | GATA2 | ARP31855_T100 | Wang, F. et al. A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis. Nucleic Acids Res. 42, 442-57 (2014). 24049083 | 24049083 |
| 998 | GATA4 | OAAF01049 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
| 999 | GATA6 | ARP31859_P050 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
| 1000 | GCDH | ARP43559_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1001 | GCK | ARP61473_P050 | Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats. Life Sci. 150, 1-7 (2016). 26883978 | 26883978 |
| 1002 | GCLC | ARP54576_P050 | Tomasi, M. L. et al. Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice. Free Radic. Biol. Med. 68, 148-58 (2014). 24296246 | 24296246 |
| 1003 | GCLC | ARP54577_P050 | Bardag-Gorce, F. et al. Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease. Exp. Mol. Pathol. 90, 123-30 (2011). 21036165 | 21036165 |
| 1004 | GCLC | ARP54577_P050 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
| 1005 | GCLC | ARP54577_P050 | Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism. Biomolecules. 9, (2019). 30823587 | 30823587 |
| 1006 | GCLC | ARP34292_P050 | Cysteine improves boar sperm quality via glutathione biosynthesis during the liquid storage. Anim Biosci 2022 2 35 166-176 34445846 | 34445846 |
| 1007 | GCLM | ARP54624_P050 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
| 1008 | GCLM | ARP54624_P050 | Tomasi, M. L. et al. Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice. Free Radic. Biol. Med. 68, 148-58 (2014). 24296246 | 24296246 |
| 1009 | GCM1 | ARP36863_P050 | Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia. Proc. Natl. Acad. Sci. U.S.A. (2016). 27791094 | 27791094 |
| 1010 | GCM1 | P100836_P050 | Baczyk, D. et al. Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast. Cell Death Differ. 16, 719-27 (2009). 19219068 | 19219068 |
| 1011 | GCM1 | P100836_P050 | Sivasubramaniyam, T. et al. Where polarity meets fusion: role of Par6 in trophoblast differentiation during placental development and preeclampsia. Endocrinology 154, 1296-309 (2013). 23341197 | 23341197 |
| 1012 | GCM1 | P100836_P050 | Kumar, P., Luo, Y., Tudela, C., Alexander, J. M. & Mendelson, C. R. The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation. Mol. Cell. Biol. 33, 1782-96 (2013). 23438603 | 23438603 |
| 1013 | GCM1 | P100836_P050 | Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation. J. Biol. Chem. 290, 30152-62 (2015). 26491013 | 26491013 |
| 1014 | GCM1 | P100836_P050 | Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis. Cell Death Dis. 8, e2590 (2017). 28151467 | 28151467 |
| 1015 | GCM1 | P100837_P050 | Drewlo, S., Czikk, M., Baczyk, D., Lye, S. & Kingdom, J. Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi. Hum. Reprod. 26, 1025-34 (2011). 21406447 | 21406447 |
| 1016 | GDF1 | OACD03794 | Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 12, 7142 (2021). 34880251 | 34880251 |
| 1017 | GDNF | OKCD05717 | Specific Expression of Glial-Derived Neurotrophic Factor in Muscles as Gene Therapy Strategy for Amyotrophic Lateral Sclerosis. Neurotherapeutics. 18, 1113-1126 (2021). 33786805 | 33786805 |
| 1018 | GEMIN4 | ARP56757_P050 | CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. Cell Death Dis. 12, 1040 (2021). 34725334 | 34725334 |
| 1019 | GFPT1 | OKEH02952 | Normalizing HIF-1α Signaling Improves Cellular Glucose Metabolism and Blocks the Pathological Pathways of Hyperglycemic Damage. Biomedicines 2021 9 9 NULL 34572324 | 34572324 |
| 1020 | GGN | ARP53093_P050 | Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice. J Cell Mol Med. 22, 4863-4874 (2018). 30055035 | 30055035 |
| 1021 | GGT1 | OKEH03351 | Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 583, 122-126 (2020). 32461692 | 32461692 |
| 1022 | GHRH | OKEH03121 | Repeated hypoglycemia remodels neural inputs and disrupts mitochondrial function to blunt glucose-inhibited GHRH neuron responsiveness. JCI Insight. 5, NULL (2020). 33148883 | 33148883 |
| 1023 | GJB1 | ARP36600_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1024 | GKN2 | ARP65440_P050 | Trefoil factor 1 and gastrokine 2 inhibit Helicobacter pylori-induced proliferation and inflammation in gastric cardia and distal carcinogenesis. Oncol Lett. 20, 318 (2020). 33133254 | 33133254 |
| 1025 | GLI1 | ARP32368_T100 | Yoshimura, K., Kawate, T. & Takeda, S. Signaling through the primary cilium affects glial cell survival under a stressed environment. Glia 59, 333-44 (2011). 21125655 | 21125655 |
| 1026 | GLI1 | ARP32368_T100 | Maitah, M. Y., Ali, S., Ahmad, A., Gadgeel, S. & Sarkar, F. H. Up-regulation of sonic hedgehog contributes to TGF-beta1-induced epithelial to mesenchymal transition in NSCLC cells. PLoS One 6, e16068 (2011). 21249152 | 21249152 |
| 1027 | GLI1 | ARP32368_T100 | Schiapparelli, P. et al. Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells. Cancer Lett. 310, 222-31 (2011). 21803487 | 21803487 |
| 1028 | GLI1 | ARP32368_T100 | Ferruzzi, P. et al. In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines. Int. J. Cancer 131, E33-44 (2012). 22072503 | 22072503 |
| 1029 | GLI1 | ARP32368_T100 | Ortega, M. C. et al. Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia 60, 851-66 (2012). 22354480 | 22354480 |
| 1030 | GLI1 | ARP32368_T100 | Pandolfi, S. et al. WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function. Oncogene 32, 4737-47 (2013). 23146903 | 23146903 |
| 1031 | GLI1 | ARP32368_T100 | Bosco-Clément, G. et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene 33, 2087-97 (2014). 23686308 | 23686308 |
| 1032 | GLI1 | ARP32368_T100 | Iwata, J. et al. Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice. Hum. Mol. Genet. 23, 182-93 (2014). 23975680 | 23975680 |
| 1033 | GLI1 | ARP32368_T100 | Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett. 24, 16 (2019). 30858866 | 30858866 |
| 1034 | GLI2 | ARP31885_P050 | Histological, cellular and behavioural analyses of effects of chemotherapeutic agent cyclophosphamide in the developing cerebellum. Cell Prolif. 52, e12608 (2019). 30932251 | 30932251 |
| 1035 | GLI2 | ARP31885_T100 | Kim, Y. et al. Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells. Cancer Res. 67, 3583-93 (2007). 17440069 | 17440069 |
| 1036 | GLI2 | ARP31885_T100 | Kiprilov, E. N. et al. Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J. Cell Biol. 180, 897-904 (2008). 18332216 | 18332216 |
| 1037 | GLI2 | ARP31885_T100 | Kabasawa, Y. et al. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas. J. Clin. Pathol. 61, 851-5 (2008). 18344235 | 18344235 |
| 1038 | GLI2 | ARP31885_T100 | Omenetti, A. et al. The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. Gut 57, 1275-82 (2008). 18375471 | 18375471 |
| 1039 | GLI2 | ARP31885_T100 | Omenetti, A. et al. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J. Clin. Invest. 118, 3331-42 (2008). 18802480 | 18802480 |
| 1040 | GLI2 | ARP31885_T100 | Takanaga, H. et al. Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells. Stem Cells 27, 165-74 (2009). 18927476 | 18927476 |
| 1041 | GLI2 | ARP31885_T100 | Madison, B. B., McKenna, L. B., Dolson, D., Epstein, D. J. & Kaestner, K. H. FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J. Biol. Chem. 284, 5936-44 (2009). 19049965 | 19049965 |
| 1042 | GLI2 | ARP31885_T100 | Wall, D. S. et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J. Cell Biol. 184, 101-12 (2009). 19124651 | 19124651 |
| 1043 | GLI2 | ARP31885_T100 | Syn, W.-K. et al. Role for hedgehog pathway in regulating growth and function of invariant NKT cells. Eur. J. Immunol. 39, 1879-92 (2009). 19544307 | 19544307 |
| 1044 | GLI2 | ARP31885_T100 | Kim, J. E. et al. Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma. Mod. Pathol. 22, 1312-20 (2009). 19593328 | 19593328 |
| 1045 | GLI2 | ARP31885_T100 | Ho, L. et al. Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell 16, 126-36 (2009). 19647223 | 19647223 |
| 1046 | GLI2 | ARP31885_T100 | Kim, W.-Y. et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nat. Neurosci. 12, 1390-7 (2009). 19801986 | 19801986 |
| 1047 | GLI2 | ARP31885_T100 | Nakamura, K. et al. Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells. PLoS One 5, e8824 (2010). 20098680 | 20098680 |
| 1048 | GLI2 | ARP31885_T100 | Youssef, K. K. et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nat. Cell Biol. 12, 299-305 (2010). 20154679 | 20154679 |
| 1049 | GLI2 | ARP31885_T100 | Peacock, Z. S., Cox, D. & Schmidt, B. L. Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor. Oral Oncol. 46, 387-92 (2010). 20371205 | 20371205 |
| 1050 | GLI2 | ARP31885_T100 | Coon, V. et al. Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma. Mol. Cancer Ther. 9, 2627-36 (2010). 20807782 | 20807782 |
| 1051 | GLI2 | ARP31885_T100 | Schneider, S. et al. Expression of the Sonic hedgehog pathway in squamous cell carcinoma of the skin and the mucosa of the head and neck. Head Neck 33, 244-50 (2011). 20848446 | 20848446 |
| 1052 | GLI2 | ARP31885_T100 | Malek, R., Matta, J., Taylor, N., Perry, M. E. & Mendrysa, S. M. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation. PLoS One 6, e17884 (2011). 21437245 | 21437245 |
| 1053 | GLI2 | ARP31885_T100 | Jung, I. H., Jung, D. E., Park, Y. N., Song, S. Y. & Park, S. W. Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PLoS One 6, e27941 (2011). 22164219 | 22164219 |
| 1054 | GLI2 | ARP31885_T100 | Yang, L. et al. Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus. Int. J. Biochem. Mol. Biol. 3, 46-57 (2012). 22509480 | 22509480 |
| 1055 | GLI2 | ARP31885_T100 | Tostar, U., Finta, C., Rahman, M. F.-U., Shimokawa, T. & Zaphiropoulos, P. G. Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant. PLoS One 7, e37761 (2012). 22666390 | 22666390 |
| 1056 | GLI2 | ARP31885_T100 | Bosco-Clément, G. et al. Targeting Gli transcription activation by small molecule suppresses tumor growth. Oncogene 33, 2087-97 (2014). 23686308 | 23686308 |
| 1057 | GLI2 | ARP31885_T100 | Li, Y. et al. Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells. Genomics 102, 456-67 24121003 | 24121003 |
| 1058 | GLI2 | ARP31885_T100 | Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas. Int J Oncol. 51, 1869-1877 (2017). 29039491 | 29039491 |
| 1059 | GLI2 | ARP31885_T100 | Regulation of Survivin Isoform Expression by GLI Proteins in Ovarian Cancer. Cells. 8, (2019). 30736319 | 30736319 |
| 1060 | GLI-2 | ARP31885_P050 | Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy. PLoS ONE. 11, e0167665 (2016). 27918595 | 27918595 |
| 1061 | GLIS2 | ARP30037_P050 | Attanasio, M. et al. Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis. Nat. Genet. 39, 1018-24 (2007). 17618285 | 17618285 |
| 1062 | GLIS2 | ARP30037_P050 | Prominin-1 controls stem cell activation by orchestrating ciliary dynamics. EMBO J. 38, (2019). 30523147 | 30523147 |
| 1063 | GLIS2 | ARP30037_P050 | An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis. Sci Adv. 7, eabf6063 (2021). 34705506 | 34705506 |
| 1064 | GLRA1 | OAPC00117 | Non-uniform changes in membrane receptors in the rat urinary bladder following outlet obstruction. Eur. J. Pharmacol. 762, 82-8 (2015). 26004535 | 26004535 |
| 1065 | GLS | ARP55098_P050 | Glutamine fuels proliferation but not migration of endothelial cells. EMBO J. 36, 2321-2333 (2017). 28659379 | 28659379 |
| 1066 | GLS2 | ARP43562_T100 | Toriumi, K. et al. Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex. Neuropsychopharmacology 37, 1387-96 (2012). 22257896 | 22257896 |
| 1067 | GLS2 | ARP43562_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1068 | GLUD1 | ARP45709_P050 | Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues. Mol. Cell. Endocrinol. 415, 1-11 (2015). 26241911 | 26241911 |
| 1069 | GLUD1 | ARP45709_P050 | Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions. Neurochem. Res. 42, 92-107 (2017). 27422263 | 27422263 |
| 1070 | GLUT9 | ARP43757_P050 | Hormonal and Chemical Regulation of the Glut9 Transporter in Mice. J. Pharmacol. Exp. Ther. 360, 206-214 (2017). 27807007 | 27807007 |
| 1071 | GNAI3 | OAAB19207 | Vincent DiGiacomo, et al. Probing the mutational landscape of regulators of G protein signaling proteins in cancer. (2020). 32019900 | 32019900 |
| 1072 | GNAS | ARP42693_P050 | Masyuk, A. I. et al. Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G1013-24 (2013). 23578785 | 23578785 |
| 1073 | GNAS | ARP42693_P050 | Moreno-Smith, M. et al. Biologic effects of dopamine on tumor vasculature in ovarian carcinoma. Neoplasia 15, 502-10 (2013). 23633922 | 23633922 |
| 1074 | GNAT3 | OAEB00418 | Immunohistochemical Analysis of Human Vallate Taste Buds. Chem Senses. 40, 655-60 (2015). 26400924 | 26400924 |
| 1075 | GNAT3 | OAEB00418 | The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci. 35, 15984-95 (2015). 26631478 | 26631478 |
| 1076 | GNAT3 | OAEB00418 | 5-HT3A -driven green fluorescent protein delineates gustatory fibers innervating sour-responsive taste cells: A labeled line for sour taste?. J Comp Neurol. 525, 2358-2375 (2017). 28316078 | 28316078 |
| 1077 | GNAT3 | OAEB00418 | Michael A Kohanski, et al. Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps. 460-469.e7 (2018). 29778504 | 29778504 |
| 1078 | GNAT3 | OAEB00418 | Chemical receptors of the arytenoid: A comparison of human and mouse. Laryngoscope. 130, 423-430 (2020). 30908677 | 30908677 |
| 1079 | GNAT3 | OAEB00418 | Expression of Bitter Taste Receptors and Solitary Chemosensory Cell Markers in the Human Sinonasal Cavity. Chem Senses. 44, 483-495 (2019). 31231752 | 31231752 |
| 1080 | GNAT3 | OAEB00418 | A Subset of Olfactory Sensory Neurons Express Forkhead Box J1-Driven eGFP. Chem Senses. 44, 663-671 (2019). 31504289 | 31504289 |
| 1081 | GNAT3 | OAEB00418 | Zika virus infection in chemosensory cells. J Neurovirol. 26, 371-381 (2020) 32144727 | 32144727 |
| 1082 | GNAT3 | OAEB00418 | Functional expression of TMEM16A in taste bud cells. J Physiol. 599, 3697-3714 (2021) 34089532 | 34089532 |
| 1083 | GNAT3 | OAEB00418 | Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor. Front Neuroanat. 15, 751839 (2021). 34776881 | 34776881 |
| 1084 | GNAT3 | OAEB00418 | Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor. Front Neuroanat. 15, 751839 (2021). 34578940 | 34578940 |
| 1085 | GNAT3 | OPED00033 | METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis. Int J Oral Sci 2022 1 14 26 35581183 | 35581183 |
| 1086 | GNB3 | OALA06860 | No evidence for age-related alterations in the marmoset retina.Front Neuroanat94529516NULLSeptember2022 | 36120100 |
| 1087 | GNMT | ARP43565_P050 | Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metab. 25, 1320-1333.e5 (2017). 28591635 | 28591635 |
| 1088 | GOT1 | ARP48205_P050 | Takeda, K., Ishida, A., Takahashi, K. & Ueda, T. Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from a-ketoglutarate for vesicular loading. J. Neurochem. 121, 184-96 (2012). 22309504 | 22309504 |
| 1089 | GOT1 | ARP48205_P050 | Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). 23704975 | 23704975 |
| 1090 | GOT1 | ARP48205_T100 | Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One. 8, e64093 (2013). 23704975 | 23704975 |
| 1091 | GOT2 | ARP43517_P050 | Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). 23704975 | 23704975 |
| 1092 | GOT2 | ARP43517_T100 | Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One. 8, e64093 (2013). 23704975 | 23704975 |
| 1093 | GOT2 | ARP43518_T100 | Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans. Antioxidants (Basel). 10 (2021). 34573075 | 34573075 |
| 1094 | GOT2 | OAAB18690 | The day/night proteome in the murine heart. Am J Physiol Regul Integr Comp Physiol 2014 2 307 R121-37 24789993 | 24789993 |
| 1095 | GP1BA | ARP51319_P050 | Temperature effects on the activity, shape, and storage of platelets from 13-lined ground squirrels. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (2017). 28332020 | 28332020 |
| 1096 | GPC1 | OALA07435 | Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. Exp Gerontol 2019 NULL 126 110693 31430521 | 31430521 |
| 1097 | GPC3 | ARP37665_T100 | Bhave, V. S. et al. Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex. Am. J. Pathol. 183, 153-9 (2013). 23665349 | 23665349 |
| 1098 | GPC3 | ARP37665_T100 | Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector. Oncotarget. 8, 24785-24796 (2017). 28445973 | 28445973 |
| 1099 | GPC4 | ARP64505_P050 | Walshe, J. & Harkin, D. G. Serial explant culture provides novel insights into the potential location and phenotype of corneal endothelial progenitor cells. Exp. Eye Res. 127, 9-13 (2014). 25035050 | 25035050 |
| 1100 | GPER1 | ARP62244_P050 | Steroid regulation of early postnatal development in the corpus epididymidis of pigs. J Endocrinol. 225, 125-34 (2015). 25876610 | 25876610 |
| 1101 | GPR12 | ARP64695_P050 | A Thalamic Orphan Receptor Drives Variability in Short-Term Memory. Cell. 183, 522-536.e19 (2020). 32997977 | 32997977 |
| 1102 | GPR162 | ARP68400_P050 | Orphan receptor GPR158 controls stress-induced depression. Elife. 7, (2018). 29419376 | 29419376 |
| 1103 | GPRC5B | ARP59799_P050 | Orphan receptor GPR158 controls stress-induced depression. Elife. 7, (2018). 29419376 | 29419376 |
| 1104 | GPRC6A | ARP64455_P050 | Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice. J Bone Miner Res. 34, 1517-1530 (2019) 30908701 | 30908701 |
| 1105 | GPX1 | OAAF05777 | Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med. 42, 789-798 (2018). 29717771 | 29717771 |
| 1106 | GPX3 | ARP41491_P050 | Maccarrone, G. et al. Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters. J. Psychiatr. Res. 47, 1572-80 (2013). 23962679 | 23962679 |
| 1107 | GPX3 | ARP41491_P050 | Methionine supply alters mammary gland antioxidant gene networks via phosphorylation of nuclear factor erythroid 2-like 2 (NFE2L2) protein in dairy cows during the periparturient period. J Dairy Sci. 101, 8505-8512 (2018). 29908802 | 29908802 |
| 1108 | GRHL3 | ARP33196_P050 | Yu, Z., Mannik, J., Soto, A., Lin, K. K. & Andersen, B. The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 28, 1890-903 (2009). 19494835 | 19494835 |
| 1109 | GRHL3 | ARP39489_P050 | Sakurai, T. et al. Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training. Biochem. Biophys. Res. Commun. 416, 125-9 (2011). 22094257 | 22094257 |
| 1110 | GRHL3 | ARP39489_T100 | Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Front Cell Dev Biol. 9, 718066 (2021) 34660580 | 34660580 |
| 1111 | GRIK2 | ARP35515_T100 | Funk, J. A. et al. Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid. J. Am. Soc. Nephrol. 25, 1187-97 (2014). 24511141 | 24511141 |
| 1112 | GRK5 | ARP54750_P050 | The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5. Sci Rep. 6, 33231 (2016). 27618959 | 27618959 |
| 1113 | GSC | ARP32174_P050 | Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. Neurotoxicol Teratol. 52, 181-93 (2015). 26386178 | 26386178 |
| 1114 | GSDMD | OKCD01821 | Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity.Front Immunol89447013NULLJune2022 | 35663992 |
| 1115 | GSK3B | OKCD08452 | Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated with Insulin Resistance in Overweight and Obese Midlife Adults. Nutrients. 12, NULL (2020). 32486256 | 32486256 |
| 1116 | GSK3B | OKEH03023 | Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model. Saudi Pharm J 2022 1 30 72-90 35145347 | 35145347 |
| 1117 | GSS | OAAB04008 | Ramani, K., Tomasi, M. L., Yang, H., Ko, K. & Lu, S. C. Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. J. Biol. Chem. 287, 36341-55 (2012). 22942279 | 22942279 |
| 1118 | GSTM | ARP41769_P050 | Bates, D. J. et al. MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging. Aging Cell 9, 1-18 (2010). 19878148 | 19878148 |
| 1119 | GSTM1 | ARP41769_P050 | Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows. J Proteomics. 158, 52-61 (2017). 28238905 | 28238905 |
| 1120 | GSTM3 | ARP53561_P050 | GSTM3, but not IZUMO1, is a cryotolerance marker of boar sperm. J Anim Sci Biotechnol. 10, 61 (2019). 31391940 | 31391940 |
| 1121 | GSTM3 | ARP53561_P050 | Glutathione S-Transferases Play a Crucial Role in Mitochondrial Function, Plasma Membrane Stability and Oxidative Regulation of Mammalian Sperm. Antioxidants (Basel). 9, (2020). 31991648 | 31991648 |
| 1122 | GTPBP9 | ARP40744_P050 | Zhang, J., Rubio, V., Lieberman, M. W. & Shi, Z.-Z. OLA1, an Obg-like ATPase, suppresses antioxidant response via nontranscriptional mechanisms. Proc. Natl. Acad. Sci. U. S. A. 106, 15356-61 (2009). 19706404 | 19706404 |
| 1123 | GUCY2X | OACA09780 | Role of uroguanylin's signalling pathway in the development of ischaemic stroke.Eur J Neurosci3720-3737561July2022 | 35445449 |
| 1124 | GUSB | ARP44234_T100 | Beta-Glucuronidase Catalyzes Deconjugation and Activation of Curcumin-Glucuronide in Bone. J Nat Prod. 82, 500-509 (2019). 30794412 | 30794412 |
| 1125 | GUSB | ARP44234_T100 | Chemopreventive efficacy of oral curcumin: a prodrug hypothesis. FASEB J. 33, 9453-9465 (2019) 31136203 | 31136203 |
| 1126 | GUSB | ARP44234_T100 | Bone-Specific Metabolism of Dietary Polyphenols in Resorptive Bone Diseases. Mol Nutr Food Res. 64, e2000072 (2020) 32506808 | 32506808 |
| 1127 | GW182 | ARP40956_P050 | Bukong, T. N., Hou, W., Kodys, K. & Szabo, G. Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology 57, 70-80 (2013). 22898980 | 22898980 |
| 1128 | GZMB | OAAF01817 | Influenza A surface glycosylation and vaccine design. Proc. Natl. Acad. Sci. U.S.A. 114, 280-285 (2017). 28028222 | 28028222 |
| 1129 | GZMH | ARP42686_T100 | Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. J Immunol Methods. 453, 44472 (2018). 28322863 | 28322863 |
| 1130 | H1FX | OAAB10031 | Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis. Mol Cell. 72, 84-98.e9 (2018). 30220558 | 30220558 |
| 1131 | H2AFX | ARP58280_P050 | Wen, W. et al. MST1 promotes apoptosis through phosphorylation of histone H2AX. J. Biol. Chem. 285, 39108-16 (2010). 20921231 | 20921231 |
| 1132 | HA | OAPB00912 | Huang, H. et al. NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression. Oncotarget 5, 493-505 (2014). 24457827 | 24457827 |
| 1133 | HA Tag | OAEA00009 | Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations. J Allergy Clin Immunol. 143, 1549-1559.e6 (2019). 30092288 | 30092288 |
| 1134 | HA Tag | OAEA00009 | Hyperactivation of Oncogenic JAK3 Mutants Depend on ATP Binding to the Pseudokinase Domain. Front Oncol. 8, 560 (2018). 30560087 | 30560087 |
| 1135 | HA Tag | OAEA00009 | Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling. Cancers (Basel). 12, (2019). 31892268 | 31892268 |
| 1136 | HA Tag | OAEA00010 | Actinin-4 Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors. J Biol Chem. 290, 15909-20 (2015). 25944910 | 25944910 |
| 1137 | HA Tag | OAEA00010 | The unassembled flavoprotein subunits of human and bacterial complex II have impaired catalytic activity and generate only minor amounts of ROS. J Biol Chem. 293, 7754-7765 (2018). 29610278 | 29610278 |
| 1138 | HA Tag | OAEA00010 | Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice. J Cell Mol Med. 22, 4863-4874 (2018). 30055035 | 30055035 |
| 1139 | HADHB | ARP48133_P050 | Gerin, I. et al. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J. Biol. Chem. 285, 33652-61 (2010). 20732877 | 20732877 |
| 1140 | HADHB | ARP48133_P050 | The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arterioscler Thromb Vasc Biol. 35, 787-95 (2015). 25593129 | 25593129 |
| 1141 | HADHB | ARP48133_P050 | TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling. Am. J. Physiol. Heart Circ. Physiol. 311, H64-75 (2016). 27199118 | 27199118 |
| 1142 | HADHB | ARP48133_P050 | Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy. J Mol Cell Cardiol. 138, 304-317 (2020). 31836543 | 31836543 |
| 1143 | HAL | ARP45694_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1144 | HAMP | OKEH01408 | A role of PIEZO1 in iron metabolism in mice and humans. Cell. 184, 969-982.e13 (2021). 33571427 | 33571427 |
| 1145 | HAS3 | OKCA01302 | A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid.Skin Pharmacol Physiol112-123352August2021 | 34348350 |
| 1146 | HBA1C | OKEH00660 | Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection. Nat Metab. (2021). 34035524 | 34035524 |
| 1147 | HBA1C | OKEH00661 | Mast cell-deficiency protects mice from streptozotocin-induced diabetic cardiomyopathy. Transl Res. 208, 1-14 (2019). 30738862 | 30738862 |
| 1148 | HBA1C | OKEH00661 | Amelioration of diabetic nephropathy using pomegranate peel extract-stabilized gold nanoparticles: assessment of NF-κB and Nrf2 signaling system. Int J Nanomedicine. 14, 1753-1777 (2019). 30880978 | 30880978 |
| 1149 | HBA1C | OKEH00661 | Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass. e1008586 (2020). 32463816 | 32463816 |
| 1150 | HBC | OAAI00128 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun. 10, 2184 (2019). 31097716 | 31097716 |
| 1151 | HBP1 | ARP38977_P050 | Li, H., Bian, C., Liao, L., Li, J. & Zhao, R. C. miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1. Breast Cancer Res. Treat. 126, 565-75 (2011). 20505989 | 20505989 |
| 1152 | HBP1 | ARP38977_P050 | Wang, W., Pan, K., Chen, Y., Huang, C. & Zhang, X. The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression. Nucleic Acids Res. 40, 981-95 (2012). 21967847 | 21967847 |
| 1153 | HDAC2 | ARP32618_P050 | Mta2 promotes Tipin-dependent maintenance of replication fork integrity. Cell Cycle. 13, 2120-8 (2014). 24830473 | 24830473 |
| 1154 | HDAC3 | OAAB09604 | Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration. Exp Biol Med (Maywood). 243, 627-638 (2018). 29486577 | 29486577 |
| 1155 | HDAC9 | ARP42788_T100 | Milde, T. et al. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin. Cancer Res. 16, 3240-52 (2010). 20413433 | 20413433 |
| 1156 | HDAC9 | ARP42788_T100 | Hang, C. T. et al. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466, 62-7 (2010). 20596014 | 20596014 |
| 1157 | HDAC9 | ARP42788_T100 | Spallotta, F. et al. Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia. J. Biol. Chem. 288, 22915-29 (2013). 23836913 | 23836913 |
| 1158 | HDL | OKEH00700 | PCSK9 is minimally associated with HDL but impairs the anti-atherosclerotic HDL effects on endothelial cell activation.J Lipid Res1002726310October2022 | 36067830 |
| 1159 | HECTD2 | ARP43481_P050 | Sun, T. et al. MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A. Oncogene (2013). doi:10.1038/onc.2013.230 23770851 | 23770851 |
| 1160 | HEMGN | ARP57794_P050 | Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 7, (2018). 30097520 | 30097520 |
| 1161 | Heparan sulfate | OKEH02552 | Glycocalyx Preservation and NO Production in Fatty Livers-The Protective Role of High Molecular Polyethylene Glycol in Cold Ischemia Injury. Int J Mol Sci. 19, (2018). 30103565 | 30103565 |
| 1162 | HES1 | ARP32372_T100 | Tilley, A. E. et al. Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 179, 457-66 (2009). 19106307 | 19106307 |
| 1163 | HES1 | ARP32372_T100 | Schreck, K. C. et al. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clin. Cancer Res. 16, 6060-70 (2010). 21169257 | 21169257 |
| 1164 | HES1 | ARP32372_T100 | Ma, W. et al. hCLP46 regulates U937 cell proliferation via Notch signaling pathway. Biochem. Biophys. Res. Commun. 408, 84-8 (2011). 21458412 | 21458412 |
| 1165 | HES1 | ARP32372_T100 | Bennani-Baiti, I. M. et al. Notch signalling is off and is uncoupled from HES1 expression in Ewing’s sarcoma. J. Pathol. 225, 353-63 (2011). 21984123 | 21984123 |
| 1166 | HES1 | ARP32372_T100 | Asnaghi, L. et al. Notch signaling promotes growth and invasion in uveal melanoma. Clin. Cancer Res. 18, 654-65 (2012). 22228632 | 22228632 |
| 1167 | HES1 | ARP32372_T100 | Guiu, J. et al. Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J. Exp. Med. 210, 71-84 (2013). 23267012 | 23267012 |
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| 1169 | Hes1 | ARP32372_T100 | Ma, L. et al. Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits. Biochem. Biophys. Res. Commun. 450, 353-9 (2014). 24944018 | 24944018 |
| 1170 | HES1 | ARP32372_T100 | Asnaghi, L. et al. Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation. PLoS One 9, e105372 (2014). 25166211 | 25166211 |
| 1171 | HES1 | ARP32372_T100 | Therapeutic targeting of HES1 transcriptional programs in T-ALL. Blood. 125, 2806-14 (2015). 25784680 | 25784680 |
| 1172 | HES1 | ARP32372_T100 | Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. Neuroscience. 306, 100-14 (2015). 26299339 | 26299339 |
| 1173 | HES1 | ARP32372_T100 | Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres. Brain Pathol. 26, 713-723 (2016). 26613556 | 26613556 |
| 1174 | HES1 | ARP32372_T100 | CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A. Oncogene. 37, 128-138 (2018). 28892048 | 28892048 |
| 1175 | HES1 | ARP32372_T100 | A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal. Dis Model Mech. 12, (2019). 30910991 | 30910991 |
| 1176 | HES7 | ARP37926_P050 | Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis. Mol Med Rep. 15, 1441-1454 (2017). 28259916 | 28259916 |
| 1177 | HEY1 | ARP32512_P050 | Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. Neuroscience. 306, 100-14 (2015). 26299339 | 26299339 |
| 1178 | HEY1 | ARP32512_P050 | Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma. Neoplasia. 20, 1023-1037 (2018). 30195713 | 30195713 |
| 1179 | HEYL | ARP31866_T100 | Morrow, D. et al. Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A. Arterioscler. Thromb. Vasc. Biol. 29, 1112-8 (2009). 19407245 | 19407245 |
| 1180 | HGF | ARP44317_P050 | Sen, B., Peng, S., Saigal, B., Williams, M. D. & Johnson, F. M. Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer. Clin. Cancer Res. 17, 514-24 (2011). 21106725 | 21106725 |
| 1181 | HGF | ARP44317_P050 | Williams, C. M. et al. Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Eng. Part A 17, 1055-68 (2011). 21121876 | 21121876 |
| 1182 | HGF | ARP44317_P050 | Zampell, J. C. et al. Lymphatic function is regulated by a coordinated expression of lymphangiogenic and anti-lymphangiogenic cytokines. Am. J. Physiol. Cell Physiol. 302, C392-404 (2012). 21940662 | 21940662 |
| 1183 | HGF | ARP44317_P050 | Ji, R. et al. The differentiation of MSCs into functional hepatocyte-like cells in a liver biomatrix scaffold and their transplantation into liver-fibrotic mice. Biomaterials 33, 8995-9008 (2012). 22985996 | 22985996 |
| 1184 | HGF | ARP44317_P050 | Nejak-Bowen, K., Orr, A., Bowen, W. C. & Michalopoulos, G. K. Conditional genetic elimination of hepatocyte growth factor in mice compromises liver regeneration after partial hepatectomy. PLoS One 8, e59836 (2013). 23527275 | 23527275 |
| 1185 | HGF | ARP44317_P050 | Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion. PLoS One. 10, e0126859 (2015). 25978399 | 25978399 |
| 1186 | HIF1A | ARP38054_P050 | Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells. Sci Rep. 9, 14746 (2019). 31611601 | 31611601 |
| 1187 | HIF1A | OKEH00594 | Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing. JBMR Plus. 5, e10425 (2021). 33869985 | 33869985 |
| 1188 | HIF1A | ARP31591_P050 | Organ-specific effects on glycolysis by the dioxin-activated aryl hydrocarbon receptor. PLoS One 2020 12 15 e0243842 33320884 | 33320884 |
| 1189 | HIPK2 | ARP32586_P050 | Choi, D. W. et al. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1. J. Biol. Chem. 283, 4682-9 (2008). 18093972 | 18093972 |
| 1190 | HIPK2 | ARP32586_P050 | Steinmann, S. et al. v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300. Oncogene 28, 2446-55 (2009). 19448669 | 19448669 |
| 1191 | HIPK2 | ARP32586_P050 | Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling. J Neurosci. 31, 13746-57 (2011). 21957238 | 21957238 |
| 1192 | HIPK2 | ARP32586_P050 | Heat shock modulates the subcellular localization, stability, and activity of HIPK2. Biochem. Biophys. Res. Commun. 472, 580-4 (2016). 26972256 | 26972256 |
| 1193 | His | OAEA00010 | P120 catenin potentiates constitutive E-cadherin dimerization at the plasma membrane and regulates trans binding.Curr Biol3017-3027.e73114July2021 | 34019823 |
| 1194 | His Tag | OAEA00010 | JiHong Li, et al. Evidence That VirS Is a Receptor for the Signaling Peptide of the Clostridium perfringens Agr-like Quorum Sensing System. (2020). 32934089 | 32934089 |
| 1195 | His Tag | OAEA00010 | Biochemical properties of bacterial reverse transcriptase-related (rvt) gene products: multimerization, protein priming, and nucleotide preference. Curr Genet. 64, 1287-1301 (2018) 29761210 | 29761210 |
| 1196 | His Tag | OAEA00010 | The N-Acetylglucosamine Kinase from Yarrowia lipolytica Is a Moonlighting Protein. Int J Mol Sci. 22 (2021). 34884915 | 34884915 |
| 1197 | His-tag | OAEA00010 | Leitman, J., Ulrich Hartl, F. & Lederkremer, G. Z. Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress. Nat. Commun. 4, 2753 (2013). 24217578 | 24217578 |
| 1198 | HIS-TAG | OAEA00010 | Binding of the Covalent Flavin Assembly Factor to the Flavoprotein Subunit of Complex II. J. Biol. Chem. 291, 2904-16 (2016). 26644464 | 26644464 |
| 1199 | HIS-TAG | OAEA00010 | Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions. Sci Rep. 6, 23623 (2016). 27009566 | 27009566 |
| 1200 | HK2 | ARP54303_P050 | Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth. Int J Oncol. 50, 2011-2023 (2017). 28498475 | 28498475 |
| 1201 | HLA-DRB5 | OAAB06426 | Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa. PLoS ONE. 12, e0169286 (2017). 28052121 | 28052121 |
| 1202 | HLA-F | ARP49410_P050 | HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment. Sci Rep. 10, 15750 (2020). 32978482 | 32978482 |
| 1203 | HLX | P100839_T100 | Homeobox gene HLX is a regulator of HGF/c-met-mediated migration of human trophoblast-derived cell lines. Biol Reprod. 83, 676-83 (2010). 20554918 | 20554918 |
| 1204 | HLX | P100839_T100 | The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos. Arterioscler Thromb Vasc Biol. 34, 1468-76 (2014). 24764455 | 24764455 |
| 1205 | HMGA2 | ARP44419_P050 | Decoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancer. J Pathol 2019 3 247 305-319 30374975 | 30374975 |
| 1206 | HMGB1 | OKCD04072 | Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism. Cell Microbiol. 21, e13064 (2019). 31155820 | 31155820 |
| 1207 | HMGB1 | OKCD04072 | Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment. Invest Ophthalmol Vis Sci. 61, 50 (2020). 32460314 | 32460314 |
| 1208 | HMGB1 | OKCD04072 | HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers. J Clin Invest. 128, 2419-2435 (2018) 29558368 | 29558368 |
| 1209 | HMGB1 | OKCD04072 | Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer. Am J Cancer Res. 11, 4141-4174 (2021) 34659881 | 34659881 |
| 1210 | HMGB1 | OKCD04074 | Dehydrocostus lactone suppresses ox-LDL-induced attachment of monocytes to endothelial cells. Am J Transl Res. 11, 6159-6169 (2019). 31632584 | 31632584 |
| 1211 | HMGB1 | OKCD04074 | Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. EMBO Mol Med. 12, e10812 (2020). 31930723 | 31930723 |
| 1212 | HMGB1 | OKCD04074 | Blood Levels of Free-Circulating Mitochondrial DNA in Septic Shock and Postsurgical Systemic Inflammation and Its Influence on Coagulation: A Secondary Analysis of a Prospective Observational Study. J Clin Med. 9, (2020). 32629885 | 32629885 |
| 1213 | HMGB1 | OKCD04074 | Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer. Am J Cancer Res. 11, 4141-4174 (2021) 34659881 | 34659881 |
| 1214 | HMGB1 | OKEH00424 | Combination with SGT-53 overcomes tumor resistance to a checkpoint inhibitor. Oncoimmunology. 7, e1484982 (2018). 30288347 | 30288347 |
| 1215 | HMGB1 | OKEH00424 | Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death. Acta Pharm Sin B 2022 6 12 2740-2750 35755291 | 35755291 |
| 1216 | HMGB1 | OKCD04074 | Platelet Toll-like Receptor 4-Related Innate Immunity Potentially Participates in Transfusion Reactions Independent of ABO Compatibility: An Ex Vivo Study. Biomedicines 2021 1 10 NULL 35052709 | 35052709 |
| 1217 | HMGCS2 | ARP41562_T100 | Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats. J Lipid Res. 54, 1369-84 (2013). 23449193 | 23449193 |
| 1218 | HMGCS2 | ARP41562_T100 | Karimian Azari, E., Leitner, C., Jaggi, T., Langhans, W. & Mansouri, A. Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-a agonist Wy-14643 in high-fat diet fed rats. PLoS One 8, e74869 (2013). 24069361 | 24069361 |
| 1219 | HMGCS2 | ARP41562_T100 | Metabolic Adaptation of the Small Intestine to Short- and Medium-Term High-Fat Diet Exposure. J. Cell. Physiol. 232, 167-75 (2017). 27061934 | 27061934 |
| 1220 | HMGN1 | ARP38532_P050 | Lane, A. A. et al. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nat. Genet. 46, 618-23 (2014). 24747640 | 24747640 |
| 1221 | Hmox1 | ARP45222_P050 | Kawahara, G. et al. Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Hum. Mol. Genet. 23, 1869-78 (2014). 24234649 | 24234649 |
| 1222 | HMOX1 | ARP42352_P050 | Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Hum Mol Genet 2015 15 24 4480-1 26034133 | 26034133 |
| 1223 | HMX1 | ARP32629_P050 | A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas. PLoS One. 9, e100096 (2014). 24945320 | 24945320 |
| 1224 | HNF-1a | ARP51375_P050 | Scheving, L. A. et al. Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice. Am. J. Physiol. Gastrointest. Liver Physiol. 306, G370-81 (2014). 24407590 | 24407590 |
| 1225 | HNF4A | ARP31946_P050 | Schmidt, D. et al. A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res. 20, 578-88 (2010). 20219941 | 20219941 |
| 1226 | HNF4A | ARP31946_P050 | Faure, A. J. et al. Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules. Genome Res. 22, 2163-75 (2012). 22780989 | 22780989 |
| 1227 | HNF4A | ARP31946_P050 | AHT-ChIP-seq: a completely automated robotic protocol for high-throughput chromatin immunoprecipitation. Genome Biol. 14, R124 (2013). 24200198 | 24200198 |
| 1228 | HNF4A | ARP31946_P050 | Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice. J Biol Chem. 289, 3105-13 (2014). 24318876 | 24318876 |
| 1229 | hnRNP LL | ARP41102_T100 | Liu, G., Lei, L., Yu, J., Kung, S. & Xie, J. Refinement of the spectra of exon usage by combined effects of extracellular stimulus and intracellular factors. Biochim. Biophys. Acta 1839, 537-45 (2014). 24844182 | 24844182 |
| 1230 | HNRNPA1 | ARP40383_T100 | Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev. 23, 482-95 (2009). 19240134 | 19240134 |
| 1231 | hnRNPA1 | ARP40383_T100 | Li, S. et al. Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX. J. Pathol. 218, 327-36 (2009). 19291713 | 19291713 |
| 1232 | hnRNPA1 | ARP40383_T100 | Gonen, N. & Assaraf, Y. G. The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1. J. Biol. Chem. 285, 33602-13 (2010). 20724482 | 20724482 |
| 1233 | hnRNPA1 | ARP40383_T100 | Stark, M., Bram, E. E., Akerman, M., Mandel-Gutfreund, Y. & Assaraf, Y. G. Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance. J. Biol. Chem. 286, 3741-54 (2011). 21068389 | 21068389 |
| 1234 | hnRNPA1 | ARP40383_T100 | Li, S. et al. Aptamer BC15 against heterogeneous nuclear ribonucleoprotein A1 has potential value in diagnosis and therapy of hepatocarcinoma. Nucleic Acid Ther. 22, 391-8 (2012). 23062008 | 23062008 |
| 1235 | hnRNPC | ARP41037_P050 | Hayakawa, H. et al. Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress. Biochem. Biophys. Res. Commun. 403, 220-4 (2010). 21073862 | 21073862 |
| 1236 | hnRNPD | ARP40238_T100 | Kang, X., Chen, W., Kim, R. H., Kang, M. K. & Park, N.-H. Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells. Oncogene 28, 565-74 (2009). 19015635 | 19015635 |
| 1237 | hnRNPD | ARP40238_T100 | Subramaniam, K., Ooi, L. L. P. J. & Hui, K. M. Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3’-untranslated region. Cancer Lett. 297, 259-68 (2010). 20599318 | 20599318 |
| 1238 | HNRNPD | ARP40238_T100 | New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer. Cancer Lett. 436, 38-51 (2018). 30118841 | 30118841 |
| 1239 | HNRNPD | ARP40238_T100 | The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein. Cell Death Differ. 27, 632-645 (2020). 31243344 | 31243344 |
| 1240 | HNRNPDL | ARP40586_P050 | The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual window of treatment success" in RA patients.". Arthritis Res Ther. 23, 239 (2021). 34521462 | 34521462 |
| 1241 | hnRNPH3 | ARP40721_T100 | Larriba, M. J. et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS One 5, e10221 (2010). 20421926 | 20421926 |
| 1242 | HNRNPL | ARP40368_P050 | Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 178, 107-121.e18 (2019). 31251911 | 31251911 |
| 1243 | HNRNPL | ARP40368_P050 | MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation. Nat Commun. 10, 5787 (2019). 31857580 | 31857580 |
| 1244 | hnRNPLL | ARP41102_T100 | Yu, J. et al. The heterogeneous nuclear ribonucleoprotein L is an essential component in the Ca2+/calmodulin-dependent protein kinase IV-regulated alternative splicing through cytidine-adenosine repeats. J. Biol. Chem. 284, 1505-13 (2009). 19017650 | 19017650 |
| 1245 | hnRNPLL | ARP41102_T100 | Rajan, P. et al. Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. BMC Cell Biol. 10, 82 (2009). 19912651 | 19912651 |
| 1246 | hnRNPLL | ARP41102_T100 | Heyd, F. & Lynch, K. W. Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing. Mol. Cell 40, 126-37 (2010). 20932480 | 20932480 |
| 1247 | hnRNPM | ARP40620_P050 | Huelga, S. C. et al. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. Cell Rep. 1, 167-78 (2012). 22574288 | 22574288 |
| 1248 | HNRNPM | ARP36993_P050 | The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules. Mol Cell 2020 1 79 54-67.e7 32521226 | 32521226 |
| 1249 | HNRPA3 | ARP41195_T100 | Süss, C. et al. Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells. Mol. Cell. Proteomics 8, 393-408 (2009). 18854578 | 18854578 |
| 1250 | HNRPA3 | ARP41195_T100 | Papadopoulou, C., Patrinou-Georgoula, M. & Guialis, A. Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes. Biochim. Biophys. Acta 1804, 692-703 (2010). 19931428 | 19931428 |
| 1251 | HNRPAB | ARP41036_T100 | Bubenik, J. L., Ladd, A. N., Gerber, C. A., Budiman, M. E. & Driscoll, D. M. Known turnover and translation regulatory RNA-binding proteins interact with the 3’ UTR of SECIS-binding protein 2. RNA Biol. 6, 73-83 (2009). 19106619 | 19106619 |
| 1252 | HNRPAB | ARP41036_T100 | Taga, Y., Miyoshi, M., Okajima, T., Matsuda, T. & Nadano, D. Identification of heterogeneous nuclear ribonucleoprotein A/B as a cytoplasmic mRNA-binding protein in early involution of the mouse mammary gland. Cell Biochem. Funct. 28, 321-8 (2010). 20517897 | 20517897 |
| 1253 | HNRPDL | ARP40586_P050 | Anderson, E. S. et al. The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. RNA 18, 1041-9 (2012). 22456266 | 22456266 |
| 1254 | HNRPDL | ARP40586_P050 | Li, X., Johansson, C., Glahder, J., Mossberg, A.-K. & Schwartz, S. Suppression of HPV-16 late L1 5’-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs. Nucleic Acids Res. 41, 10488-508 (2013). 24013563 | 24013563 |
| 1255 | HNRPF | ARP40565_T100 | White, R. et al. Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis. J. Biol. Chem. 287, 1742-54 (2012). 22128153 | 22128153 |
| 1256 | HNRPH1 | ARP45086_P050 | Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell 2019 1 178 107-121.e18 31251911 | 31251911 |
| 1257 | HO1 | OKDD00602 | Amelioration of Cisplatin-Induced Ototoxicity in Rats by L-arginine: The Role of Nitric Oxide, Transforming Growth Factor Beta 1 and Nrf2/HO-1 Pathway. Asian Pac J Cancer Prev. 21, 2155-2162 (2020). 32711445 | 32711445 |
| 1258 | HO1 | OKDD00602 | Effect of fish oil and telmisartan on dehydroepiandrosterone-induced polycystic ovarian syndrome in rats: The role of oxidative stress, transforming growth factor beta-1, and nuclear factor kappa B. Food Sci Nutr. 8, 5149-5159 (2020). 32994975 | 32994975 |
| 1259 | HOIP | ARP43241_P050 | HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 13, e1006162 (2017). 28103322 | 28103322 |
| 1260 | HOMER1 | ARP40181_P050 | CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors. Mol Autism. 9, 23 (2018). 29619162 | 29619162 |
| 1261 | HOMER1 | ARP40181_P050 | Social Deficits and Repetitive Behaviors Are Improved by Early Postnatal Low-Dose VPA Intervention in a Novel shank3-Deficient Zebrafish Model. Front Neurosci. 15, 682054 (2021). 34566559 | 34566559 |
| 1262 | HOXA10 | P100767_T100 | Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). 20036708 | 20036708 |
| 1263 | HOXA13 | ARP31955_P050 | Villavicencio-Lorini, P. et al. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J. Clin. Invest. 120, 1994-2004 (2010). 20458143 | 20458143 |
| 1264 | HOXA2 | ARP38856_P050 | Billon, N. et al. Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development. Genome Biol. 11, R80 (2010). 20678241 | 20678241 |
| 1265 | HOXA5 | ARP31447_P050 | Boucherat, O. et al. Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am. J. Physiol. Lung Cell. Mol. Physiol. 304, L817-30 (2013). 23585229 | 23585229 |
| 1266 | HOXA7 | OAAB10779 | Epigenetic dysregulation of key developmental genes in radiation-induced rat mammary carcinomas. Int J Cancer. 143, 343-354 (2018) 29435983 | 29435983 |
| 1267 | HOXA9 | ARP39932_P050 | Wang, L. et al. BRCA1 is a negative modulator of the PRC2 complex. EMBO J. 32, 1584-97 (2013). 23624935 | 23624935 |
| 1268 | HOXB13 | ARP36889_P050 | Machida, M. et al. Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle. J. Cell. Physiol. 227, 1569-76 (2012). 21529712 | 21529712 |
| 1269 | HOXC6 | ARP47054_P050 | Intrinsic control of neuronal diversity and synaptic specificity in a proprioceptive circuit. Elife 2020 NULL 9 NULL 32808924 | 32808924 |
| 1270 | HOXC9 | ARP35813_T100 | Hur, H., Lee, J.-Y., Yun, H. J., Park, B. W. & Kim, M. H. Analysis of HOX Gene Expression Patterns in Human Breast Cancer. Mol. Biotechnol. 56, 64-71 (2014). 23820980 | 23820980 |
| 1271 | HOXC9 | ARP35813_T100 | Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1. Neuro-oncology. 18, 819-29 (2016). 26582930 | 26582930 |
| 1272 | HOXD12 | ARP32647_T100 | Illig, R., Fritsch, H. & Schwarzer, C. Spatio-temporal expression of HOX genes in human hindgut development. Dev. Dyn. 242, 53-66 (2013). 23073994 | 23073994 |
| 1273 | HOXD3 | ARP31964_P050 | Kodama, A. et al. Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours. J. Comp. Pathol. 141, 199-203 19505696 | 19505696 |
| 1274 | HOXD3 | ARP31964_P050 | Kodama, A. et al. Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes. BMC Cancer 9, 363 (2009). 19825192 | 19825192 |
| 1275 | HPRT1 | OAAB03804 | Göttle, M. et al. Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease. Ann. Neurol. 76, 95-107 (2014). 24891139 | 24891139 |
| 1276 | HPSE | ARP60766_P050 | High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature. Cardiovasc Res. 112, 656-668 (2016). 27979811 | 27979811 |
| 1277 | HPSE | ARP60766_P050 | The exostosin family of glycosyltransferases: mRNA expression profiles and heparan sulphate structure in human breast carcinoma cell lines. Biosci Rep. 38, (2018). 30054430 | 30054430 |
| 1278 | HRH1 | OAEB00846 | Localization of histamine (H1, H2, H3 and H4) receptors in mouse inner ear. Acta Otolaryngol. 136, 537-44 (2016). 26854127 | 26854127 |
| 1279 | HRK | ARP46364_P050 | High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia. Leukemia. 30, 1273-81 (2016). 26987906 | 26987906 |
| 1280 | HRP | OAIA00498 | Bioaffinity-based surface immobilization of antibodies to capture endothelial colony-forming cells.PLoS Onee0269316178August2022 | 36040884 |
| 1281 | HSD11B1 | ARP45714_P050 | Lei, K. et al. Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1beta-induced COX-2 expression in human term myometrial cells. PLoS One 7, e50167 (2012). 23209664 | 23209664 |
| 1282 | HSD11B1 | ARP45714_P050 | Kuroda, K. et al. Induction of 11beta-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. Mol. Endocrinol. 27, 192-202 (2013). 23275455 | 23275455 |
| 1283 | HSD11B2 | ARP41372_P050 | Ancestral androgenic differentiation pathways are repurposed during the evolution of adult sexual plasticity. Evol Dev. 18, 285-296 (2016) 27870212 | 27870212 |
| 1284 | HSD17B13 | OAAN01691 | Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease. J Lipid Res. 60, 176-185 (2019). 30323112 | 30323112 |
| 1285 | HSD17B3 | OAAB06112 | Bertin, J., Dury, A. Y., Ouellet, J., Pelletier, G. & Labrie, F. Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction. J. Sex. Med. 11, 1949-61 (2014). 24919541 | 24919541 |
| 1286 | HSD17B6 | ARP41529_T100 | Mohler, J. L. et al. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res. 71, 1486-96 (2011). 21303972 | 21303972 |
| 1287 | HSD17B6 | ARP41529_T100 | Muthusamy, S. et al. Estrogen receptor beta and 17beta-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer. Proc. Natl. Acad. Sci. U. S. A. 108, 20090-4 (2011). 22114194 | 22114194 |
| 1288 | HSD3B1 | ARP41821_P050 | Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer. Oncotarget. 7, 62240-62254 (2016). 27557496 | 27557496 |
| 1289 | HSD3B2 | OAGA02009 | NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice. J Endocrinol. 236, 13-28 (2018). 29046340 | 29046340 |
| 1290 | HSD3B2 | OAGA02009 | Fei Wang, et al. Roles of Sialic Acid, AXL, and MER Receptor Tyrosine Kinases in Mumps Virus Infection of Mouse Sertoli and Leydig Cells. 1292 (2020). 32695074 | 32695074 |
| 1291 | HSF5 | ARP47544_P050 | Xu, Y.-M., Huang, D.-Y., Chiu, J.-F. & Lau, A. T. Y. Post-translational modification of human heat shock factors and their functions: a recent update by proteomic approach. J. Proteome Res. 11, 2625-34 (2012). 22494029 | 22494029 |
| 1292 | HSP90AA1 | ARP37729_T100 | Heat Shock Alters the Proteomic Profile of Equine Mesenchymal Stem Cells. Int J Mol Sci 2022 13 23 NULL 35806237 | 35806237 |
| 1293 | HSPA1A | ARP33096_T100 | Narjoz, C. et al. Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. Chem. Res. Toxicol. 22, 779-87 (2009). 19445531 | 19445531 |
| 1294 | HSPA1A | ARP74952_P050 | Local translation in nuclear condensate amyloid bodies. Proc Natl Acad Sci U S A. 118, NULL (2021) 33568529 | 33568529 |
| 1295 | HSPA4L | ARP53693_P050 | Expression and function of HSP110 family in mouse testis after vasectomy. Asian J. Androl. (2016). 26952955 | 26952955 |
| 1296 | HSPA8 | ARP48445_P050 | Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess a-Synuclein at Synapses. Eneuro. 7, (2020). 31941659 | 31941659 |
| 1297 | HSPA8 | ARP32253_P050 | Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity. Front Synaptic Neurosci 2022 NULL 14 855673 35573662 | 35573662 |
| 1298 | HSPB1 | ARP30177_T100 | Narjoz, C. et al. Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. Chem. Res. Toxicol. 22, 779-87 (2009). 19445531 | 19445531 |
| 1299 | HSPB1 | ARP30177_T100 | Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH). Sci Rep. 6, 22528 (2016). 26935030 | 26935030 |
| 1300 | HSPD1 | AVARP09014_P050 | Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells. Sci Rep. 9, 14746 (2019). 31611601 | 31611601 |
| 1301 | HSPH1 | ARP52217_P050 | Expression and function of HSP110 family in mouse testis after vasectomy. Asian J. Androl. (2016). 26952955 | 26952955 |
| 1302 | hTERT | OAAB01993 | Horibe, I. et al. Induction of melanogenesis by 4’-O-methylated flavonoids in B16F10 melanoma cells. J. Nat. Med. 67, 705-10 (2013). 23209831 | 23209831 |
| 1303 | HTR2B | OAAF04758 | Effects of 5-Hydroxytryptamine Class 2 Receptor Antagonists on Bronchoconstriction and Pulmonary Remodeling Processes. Am J Pathol. 188, 1113-1119 (2018). 29454752 | 29454752 |
| 1304 | HTR3A | AVARP13046_P050 | Rinaldi, A. et al. Serotonin receptor 3A expression in normal and neoplastic B cells. Pathobiology 77, 129-35 (2010). 20516728 | 20516728 |
| 1305 | HVCN1 | ARP35377_P050 | Proton channel blockers inhibit Duox activity independent of Hv1 effects. Redox Biol. 28, 101346 (2020). 31678720 | 31678720 |
| 1306 | HVCN1 | OAPB01154 | Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 6, 731-745 (2021). 33875847 | 33875847 |
| 1307 | ICTP | OKEH00680 | Oral Fluid Biomarkers for Diagnosing Gingivitis in Human: A Cross-Sectional Study. J Clin Med. 9, NULL (2020). 32503210 | 32503210 |
| 1308 | ICTP | OKEH00680 | Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma-Induced Osteolysis and Reduces Overall Survival.Cancer Res2415-2428819May2021 | 33526510 |
| 1309 | ID3 | ARP32335_T100 | Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer. BMC Cancer. 9, 173 (2009). 19500415 | 19500415 |
| 1310 | ID4 | ARP38058_T100 | Melcher, R. et al. LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability. Carcinogenesis 32, 636-42 (2011). 21297112 | 21297112 |
| 1311 | IDH2 | ARP48207_P050 | Vohwinkel, C. U. et al. Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J. Biol. Chem. 286, 37067-76 (2011). 21903582 | 21903582 |
| 1312 | IDH3A | ARP42237_T100 | Lin, C.-C. et al. Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy. Sci. Rep. 2, 785 (2012). 23139858 | 23139858 |
| 1313 | IDH3A | ARP42237_T100 | Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. CNS Neurol Disord Drug Targets. 12, 849-60 (2013). 23469839 | 23469839 |
| 1314 | IDO1 | ARP64661_P050 | l-Tryptophan-Induced Vasodilation Is Enhanced in Preeclampsia: Studies on Its Uptake and Metabolism in the Human Placenta. Hypertension. 76, 184-194 (2020) 32475317 | 32475317 |
| 1315 | IDO2 | OAAB08672 | Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. Neuro Oncol. 17, 1284-92 (2015). 26092774 | 26092774 |
| 1316 | IDO2 | OAAB08672 | Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging. 15, (2016). 27151136 | 27151136 |
| 1317 | IDO2 | OAAB08672 | Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors. J Neurooncol. 139, 239-249 (2018). 29667084 | 29667084 |
| 1318 | IER2 | ARP34401_P050 | IER2-induced senescence drives melanoma invasion through osteopontin. Oncogene. 40, 6494-6512 (2021). 34611309 | 34611309 |
| 1319 | IER5 | ARP56939_P050 | Robinson, P. M. et al. Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing. Invest. Ophthalmol. Vis. Sci. 53, 8093-103 (2012). 23139278 | 23139278 |
| 1320 | IFI35 | OKEH02088 | IFP35 as a promising biomarker and therapeutic target for the syndromes induced by SARS-CoV-2 or influenza virus. Cell Rep. 37, 110126 (2021). 34910942 | 34910942 |
| 1321 | IFIT3 | ARP46034_P050 | Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus. Sci Rep. 5, 15662 (2015). 26489762 | 26489762 |
| 1322 | IFNB1 | OAAB05131 | Sanderson, S. D. et al. Innate immune induction and influenza protection elicited by a response-selective agonist of human C5a. PLoS One 7, e40303 (2012). 22792270 | 22792270 |
| 1323 | IFNG | OPPA00471 | Upregulation of a3b1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy. J Diabetes Res. 2016, 9265074 (2016). 27340677 | 27340677 |
| 1324 | IFNGR2 | ARP46611_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 1325 | IFNLR1 | ARP32253_P050 | Pseudorabies Virus Inhibits Type I and Type III Interferon-Induced Signaling via Proteasomal Degradation of Janus Kinases. J Virol 2021 20 95 e0079321 34379505 | 34379505 |
| 1326 | IGA | OKEH00516 | Macronutrient, immunoglobulin a and total antioxidant capacity profiles of human milk from 1 to 24 months: a cross-sectional study in Thailand. Int Breastfeed J. 15, 90 (2020). 33126900 | 33126900 |
| 1327 | IGA | OKEH00516 | Effects of the thawing rate and heating temperature on immunoglobulin A and lysozyme activity in human milk. Int Breastfeed J 2022 1 17 52 35799170 | 35799170 |
| 1328 | IGF1 | OKCD05750 | Effect of fermented oyster extract on growth promotion in Sprague-Dawley rats. Integr Med Res 2020 4 9 100412 32509520 | 32509520 |
| 1329 | IGF1 | OKCD05748 | Supplementing cultured human myotubes with hibernating bear serum results in increased protein content by modulating Akt/FOXO3a signaling. PLoS One 2022 1 17 e0263085 35077510 | 35077510 |
| 1330 | IGF1R | AVARP00004_P050 | Kubota, T. et al. Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading. Acta Astronaut. 92, 73-78 (2013). 23976802 | 23976802 |
| 1331 | IGF1R | AVARP00004_P050 | Roles of progesterone receptor membrane component 1 and membrane progestin receptor alpha in regulation of zebrafish oocyte maturation. Gen Comp Endocrinol. 263, 51-61 (2018). 29649418 | 29649418 |
| 1332 | IGF2 | OAAB07463 | Modulation of IGF2 Expression in the Murine Thymus and Thymic Epithelial Cells Following Coxsackievirus-B4 Infection. Microorganisms. 9 (2021) 33672010 | 33672010 |
| 1333 | IGF2BP1 | ARP40658_P050 | Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 74, 701-712.e9 (2019). 30948266 | 30948266 |
| 1334 | IGFBP3 | OKCD05766 | Effect of fermented oyster extract on growth promotion in Sprague-Dawley rats. Integr Med Res 2020 4 9 100412 32509520 | 32509520 |
| 1335 | IGFBP4 | ARP45685_P050 | Shi, Z., Chiang, C.-I., Mistretta, T.-A., Major, A. & Mori-Akiyama, Y. SOX9 directly regulates IGFBP-4 in the intestinal epithelium. Am. J. Physiol. Gastrointest. Liver Physiol. 305, G74-83 (2013). 23660500 | 23660500 |
| 1336 | IGG | ASP00001 | Effects of Ethanol on the Expression Level of Various BDNF mRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats. Int J Mol Sci. 16, 30422-37 (2015). 26703578 | 26703578 |
| 1337 | IGG | ASP00001 | Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain. Iran J Med Sci. 42, 32-39 (2017). 28293048 | 28293048 |
| 1338 | IgG | ASP00001 | Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 7, (2018). 30097520 | 30097520 |
| 1339 | IgG | ASP00001 | Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells. Cancer Biol Ther. 13, 908-14 (2012) 22785206 | 22785206 |
| 1340 | IgG | OARA04973 | Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 7, (2018). 30097520 | 30097520 |
| 1341 | IgG-HRP | ASP00001 | Chung, W.-G., Sandoval, M. A., Sloat, B. R., Lansakara-P, D. S. P. & Cui, Z. Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1. J. Control. Release 157, 132-40 (2012). 21851843 | 21851843 |
| 1342 | IGHG2C | OASB01582 | Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nat Commun. 12, 3789 (2021) 34145279 | 34145279 |
| 1343 | IGHMBP2 | ARP38126_P050 | Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent. Mol. Ther. 24, 855-66 (2016). 26860981 | 26860981 |
| 1344 | IHH | ARP45230_T100 | Mirza, R. et al. 3beta-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species. J. Bone Miner. Metab. 30, 144-53 (2012). 21845517 | 21845517 |
| 1345 | IL12A | OKEH03774 | Inflammatory cytokine mRNA and protein levels in the synovial fluid of Mycoplasma arthritis calves. J Vet Med Sci. 83, 31-35 (2021). 33431726 | 33431726 |
| 1346 | IL13 | OKEH00100 | Magnesium augments immunosuppressive effects of a corticosteroid in obese mice with airway inflammation. Asian Pac J Allergy Immunol. (2019). 31175714 | 31175714 |
| 1347 | IL18 | OKCD00106 | NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis C.Mediators Inflamm69179192021NULLNovember2021 | 34840527 |
| 1348 | IL1A | ARP54322_P050 | Wang, F. et al. Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. Cell. Microbiol. 15, 474-85 (2013). 23083102 | 23083102 |
| 1349 | IL1A | ARP54322_P050 | Zheng, Y., Humphry, M., Maguire, J. J., Bennett, M. R. & Clarke, M. C. H. Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1a, controlling necrosis-induced sterile inflammation. Immunity 38, 285-95 (2013). 23395675 | 23395675 |
| 1350 | IL1A | OAAN00770 | MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo. J Transl Med. 17, 22 (2019). 30635008 | 30635008 |
| 1351 | IL1B | ARP54323_P050 | Wang, F. et al. Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. Cell. Microbiol. 15, 474-85 (2013). 23083102 | 23083102 |
| 1352 | IL1B | ARP54323_P050 | 1a,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients. J Alzheimers Dis. 34, 155-70 (2012). 23186989 | 23186989 |
| 1353 | IL1B | ARP54323_P050 | Circulating microparticles enhanced rat vascular wall remodeling following endothelial denudation. Am J Transl Res. 8, 4511-4522 (2016). 27904658 | 27904658 |
| 1354 | IL-1b | OAPA00159 | Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.Clin Exp Pharmacol Physiol893-902498August2022 | 35637552 |
| 1355 | IL2 | OKBB00180 | Kloog, Y. & Mor, A. Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1. Mol. Cell. Biol. 34, 978-88 (2014). 24396067 | 24396067 |
| 1356 | IL-24 | OKAG00144 | Controlled Secretion of the Anticancer Protein MDA-7 from Engineered Mesenchymal Stem Cells. Biol. Pharm. Bull. 40, 113-117 (2017). 28049944 | 28049944 |
| 1357 | IL25 | OAAB10988 | Expression of IL-25, IL-33, and Thymic Stromal Lymphopoietin in Nasal Polyp Gland Duct Epithelium in Patients With Chronic Rhinosinusitis. Am J Rhinol Allergy. 33, 378-387 (2019). 30873846 | 30873846 |
| 1358 | IL28RA | ARP48069_P050 | Mucha, J., Majchrzak, K., Taciak, B., Hellmén, E. & Król, M. MDSCs mediate angiogenesis and predispose canine mammary tumor cells for metastasis via IL-28/IL-28RA (IFN-λ) signaling. PLoS One 9, e103249 (2014). 25075523 | 25075523 |
| 1359 | IL36G | OKEH03002 | Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment. Oncoimmunology. 6, e1322238 (2017). 28680760 | 28680760 |
| 1360 | IL36G | OKEH03002 | Koss, Carolin K et al. IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice. Commun Biol. 2021; 4: 172. 33558616 | 33558616 |
| 1361 | IL36G | OKEH03002 | IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice. Commun Biol. 4, 172 (2021). 34808192 | 34808192 |
| 1362 | IL4 | OKCD05848 | Magnesium augments immunosuppressive effects of a corticosteroid in obese mice with airway inflammation. Asian Pac J Allergy Immunol. (2019). 31175714 | 31175714 |
| 1363 | IL6 | OKBB00189 | Selfe, J. et al. The effect of three different (-135°C) whole body cryotherapy exposure durations on elite rugby league players. PLoS One 9, e86420 (2014). 24489726 | 24489726 |
| 1364 | IL6 | OKBB00189 | Ota, H. et al. Pathological mechanism of musculoskeletal manifestations associated with CRPS type II: An animal study. Pain (2014). doi:10.1016/j.pain.2014.06.016 25016218 | 25016218 |
| 1365 | IL6 | OKCD05864 | Defatted Tenebrio molitor Larva Fermentation Extract Modifies Steatosis, Inflammation and Intestinal Microflora in Chronic Alcohol-Fed Rats. Nutrients. 12 (2020) 32423176 | 32423176 |
| 1366 | IL6 | OKCD05864 | The methanolic extract of Cinnamomum zeylanicum bark improves formaldehyde-induced neurotoxicity through reduction of phospho-tau (Thr231), inflammation, and apoptosis. EXCLI J. 19, 671-686 (2020) 32536837 | 32536837 |
| 1367 | IL6 | OKCD01310 | Lycium barbarum Polysaccharides and Capsaicin Inhibit Oxidative Stress, Inflammatory Responses, and Pain Signaling in Rats with Dextran Sulfate Sodium-Induced Colitis. Int J Mol Sci 2022 5 23 NULL 35269566 | 35269566 |
| 1368 | IL6 | OKCD05859 | Visually induced changes in cytokine production in the chick choroid. Elife 2021 NULL 10 NULL 34608867 | 34608867 |
| 1369 | IL-6 | OKDB00046 | In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis. J Clin Med. 8, (2019). 30866419 | 30866419 |
| 1370 | IL7R | OKEH02803 | Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy. Sci Rep. 11, 1755 (2021). 33469076 | 33469076 |
| 1371 | ILF2 | ARP35731_T100 | Jiang, D., Zhou, Y., Moxley, R. A. & Jarrett, H. W. Purification and identification of positive regulators binding to a novel element in the c-Jun promoter. Biochemistry 47, 9318-34 (2008). 18690718 | 18690718 |
| 1372 | ILF2 | ARP35731_T100 | Yamauchi, T. et al. Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression. Biochem. Biophys. Res. Commun. 425, 711-6 (2012). 22842455 | 22842455 |
| 1373 | IMMP2L | ARP60563_P050 | Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. Cell Res. 28, 625-643 (2018). 29808012 | 29808012 |
| 1374 | IMMP2L | ARP60563_P050 | Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer. Cells. 9, NULL (2020). 32717855 | 32717855 |
| 1375 | INFLUENZA-A H5N1 | OAPA00103 | Utilizing the age-related widening of the gingival crevice as a potential non-invasive vaccination route: Prospects for elderly vaccination. Exp. Gerontol. 75, 37-41 (2016). 26707909 | 26707909 |
| 1376 | INHBA | ARP54663_P050 | Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells. J Ovarian Res. 9, 71 (2016). 27793176 | 27793176 |
| 1377 | Insig2 | ARP40165_P050 | Yu, Z. et al. Rapamycin and Dietary Restriction Induce Metabolically Distinctive Changes in Mouse Liver. J. Gerontol. A. Biol. Sci. Med. Sci. glu053- (2014). doi:10.1093/gerona/glu053 24755936 | 24755936 |
| 1378 | IQCK | ARP53134_P050 | Novel Alzheimer risk factor IQ motif containing protein K is abundantly expressed in the brain and is markedly increased in patients with Alzheimer's disease.Front Cell Neurosci95407116NULLAugust2022 | 35928571 |
| 1379 | IRAK1 | OABF01186 | Afghanistan Particulate Matter Enhances Pro-Inflammatory Responses in IL-13-Exposed Human Airway Epithelium via TLR2 Signaling. Toxicol Sci. 166, 345-353 (2018). 30169750 | 30169750 |
| 1380 | IRF3 | OAAF00779 | Dong, X.-Y. et al. Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages. Virol. J. 10, 286 (2013). 24034559 | 24034559 |
| 1381 | IRF6 | ARP31995_P050 | Iwata, J. et al. Smad4-Irf6 genetic interaction and TGFbeta-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development 140, 1220-30 (2013). 23406900 | 23406900 |
| 1382 | IRF8 | ARP31199_P050 | Ye, L. et al. CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes. Hepatology 49, 753-62 (2009). 19085952 | 19085952 |
| 1383 | IRX2 | ARP32188_T100 | Kadota, M. et al. Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA. Cancer Res. 69, 7357-65 (2009). 19706770 | 19706770 |
| 1384 | IRX5 | ARP37245_P050 | Johannes Besser, et al. MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization. e113449 (2014). 25415383 | 25415383 |
| 1385 | ISG15 | OKCA02472 | Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins. Cell Rep. 31, 107772 (2020). 32553163 | 32553163 |
| 1386 | ISG20 | ARP40392_T100 | Zahoor, M. A. et al. HIV-1 Vpr Induces Interferon-Stimulated Genes in Human Monocyte-Derived Macrophages. PLoS One 9, e106418 (2014). 25170834 | 25170834 |
| 1387 | ISGF3G | ARP31200_P050 | Bidwell, B. N. et al. Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat. Med. 18, 1224-31 (2012). 22820642 | 22820642 |
| 1388 | ITGA4 | OKEH01078 | AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients. PLoS One. 14, e0219345 (2019). 31335901 | 31335901 |
| 1389 | IVL | ARP48675_P050 | Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Res. 69, 2703282 (2009). 19934318 | 19934318 |
| 1390 | JCHAIN | ARP55440_P050 | Non-invasive identification of protein biomarkers for early pregnancy diagnosis in the cheetah (Acinonyx jubatus). PLoS One. 12, e0188575 (2017). 29236714 | 29236714 |
| 1391 | JCHAIN | ARP55440_P050 | Immunoglobulin J chain as a non-invasive indicator of pregnancy in the cheetah (Acinonyx jubatus). PLoS One. 15, e0225354 (2020). 32040477 | 32040477 |
| 1392 | JHDM2A | ARP32911_T100 | Zhou, X., Sun, H., Ellen, T. P., Chen, H. & Costa, M. Arsenite alters global histone H3 methylation. Carcinogenesis 29, 1831-6 (2008). 18321869 | 18321869 |
| 1393 | JMJD2C | ARP32974_P050 | Lu, C. et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 483, 474-8 (2012). 22343901 | 22343901 |
| 1394 | JMJD2D | ARP35946_T100 | Kim, T.-D., Oh, S., Shin, S. & Janknecht, R. Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One 7, e34618 (2012). 22514644 | 22514644 |
| 1395 | JMJD2D | ARP35946_T100 | Kim, T.-D. et al. Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. Am. J. Transl. Res. 6, 236-47 (2014). 24936217 | 24936217 |
| 1396 | JOSD3 | OAAB03009 | Expression Atlas of the Deubiquitinating Enzymes in the Adult Mouse Retina, Their Evolutionary Diversification and Phenotypic Roles. PLoS ONE. 11, e0150364 (2016). 26934049 | 26934049 |
| 1397 | JUN | P100911_P050 | Russo, R. et al. The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo. FEBS J. 281, 3828-43 (2014). 25040505 | 25040505 |
| 1398 | KBTBD10 | ARP38732_T100 | du Puy, L. et al. Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments. Int. J. Dev. Biol. 56, 301-9 (2012). 22562206 | 22562206 |
| 1399 | KCC2 | OAPC00188 | Dose-dependent reversal of KCC2 hypofunction and phenobarbital-resistant neonatal seizures by ANA12. Sci Rep. 8, 11987 (2018). 30097625 | 30097625 |
| 1400 | KCC2 | OAPC00188 | Pharmaco-resistant Neonatal Seizures: Critical Mechanistic Insights from a Chemoconvulsant Model. Dev Neurobiol. 78, 1117-1130 (2018). 30136373 | 30136373 |
| 1401 | KCC2 | OAPC00188 | TrkB agonists prevent postischemic emergence of refractory neonatal seizures in mice. JCI Insight. 5, NULL (2020). 32427585 | 32427585 |
| 1402 | KCNA1 | ARP34923_P050 | Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res. Cardiol. 110, 505 (2015). 26162324 | 26162324 |
| 1403 | KCNAB2 | ARP37678_T100 | Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits. J Mol Cell Cardiol. 137, 93-106 (2019). 31639389 | 31639389 |
| 1404 | KCNH2 | ARP35450_P050 | Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure. BMC Pharmacol Toxicol. 20, 16 (2019). 30841920 | 30841920 |
| 1405 | KCNK9 | OAMA00794 | Epigenetic Dysregulation of KCNK9 Imprinting and Triple-Negative Breast Cancer. Cancers (Basel) 2021 23 13 NULL 34885139 | 34885139 |
| 1406 | KCNMA1 | ARP35092_P050 | Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis. Sci Rep. 9, 9018 (2019). 31227739 | 31227739 |
| 1407 | KCNN2 | ARP35094_T100 | Chakroborty, S. et al. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice. J. Neurosci. 32, 8341-53 (2012). 22699914 | 22699914 |
| 1408 | KCNN2 | ARP35439_P050 | Chakroborty, S. et al. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice. J. Neurosci. 32, 8341-53 (2012). 22699914 | 22699914 |
| 1409 | KCNQ1 | ARP34924_P050 | Zhou, S. et al. Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia. Heart Rhythm 5, 289-97 (2008). 18242556 | 18242556 |
| 1410 | KCNQ2 | ARP35459_T100 | Zhang, H. et al. Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents. Neuroscience 254, 70-9 (2013). 24036375 | 24036375 |
| 1411 | KCNQ2 | ARP35459_T100 | Functional responses of the hippocampus to hyperexcitability depend on directed, neuron-specific KCNQ2 K+ channel plasticity. Hippocampus. 30, 435-455 (2020) 31621989 | 31621989 |
| 1412 | KCNQ3 | OAAF00246 | Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Arch. 470, 1359-1376 (2018). 29797067 | 29797067 |
| 1413 | KCTD10 | OAAB09706 | Wang, Y. et al. KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. J. Cell. Biochem. 106, 409-13 (2009). 19125419 | 19125419 |
| 1414 | KDM4D | ARP35946_T100 | KDM4 Inhibition Targets Breast Cancer Stem-like Cells. Cancer Res. 77, 5900-5912 (2017). 28883001 | 28883001 |
| 1415 | KDM6B | ARP40101_P050 | Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Nat Commun. 8, 14922 (2017). 28387316 | 28387316 |
| 1416 | KDM6B | ARP59911_P050 | Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev 2009 10 23 1177-82 19451218 | 19451218 |
| 1417 | KDR | OAEC00429 | Silence of lncRNA UCA1 Represses the Growth and Tube Formation of Human Microvascular Endothelial Cells Through miR-195. Cell Physiol Biochem. 49, 1499-1511 (2018). 30205377 | 30205377 |
| 1418 | KEAP1 | ARP34728_T100 | Protein levels in Keap1-Nrf2 system in human failing heart. Int. J. Cardiol. 225, 62-64 (2016). 27710805 | 27710805 |
| 1419 | KEAP1 | | Virus Infection Induces Keap1 Binding to Cytokine Genes, Which Recruits NF-κB p50 and G9a-GLP and Represses Cytokine Transcription. J Immunol 2021 5 207 1437-1447 34400522 | 34400522 |
| 1420 | KHSRP | ARP40474_P050 | Ahn, Y.-H. et al. Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc. Natl. Acad. Sci. U. S. A. 107, 9590-5 (2010). 20439747 | 20439747 |
| 1421 | KIAA0317 | ARP44874_P050 | Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4. J Exp Med. 2016 May 30; 213(6): 1029-1046. 27162139 | 27162139 |
| 1422 | KIF17 | ARP57461_P050 | Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis. Cell Biosci. 11, 102 (2021). 34074333 | 34074333 |
| 1423 | KIF21A | ARP33932_P050 | Shen, X. et al. Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A. Proc. Natl. Acad. Sci. U. S. A. 105, 18788-93 (2008). 19020088 | 19020088 |
| 1424 | KIF2B | ARP34082_P050 | Shrestha, R. L. & Draviam, V. M. Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK. Curr. Biol. 23, 1514-26 (2013). 23891108 | 23891108 |
| 1425 | Kif3B | ARP33908_P050 | Weisschuh, N., Alavi, M. V, Bonin, M. & Wissinger, B. Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach. Exp. Eye Res. 85, 450-61 (2007). 17663987 | 17663987 |
| 1426 | KIF4A | OAGA05174 | Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models. EMBO Mol Med. 13, e13144 (2021). 33660397 | 33660397 |
| 1427 | KIF5B | ARP33903_P050 | Turner, L. S. et al. Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide. Prostate Cancer Prostatic Dis. 14, 30-7 (2011). 21116286 | 21116286 |
| 1428 | KIM1 | OABB00585 | Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation. J. Urol. 194, 1806-15 (2015). 26239336 | 26239336 |
| 1429 | KIRREL | ARP47408_P050 | Ito, M. et al. Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice. PLoS One 7, e29873 (2012). 22253810 | 22253810 |
| 1430 | KISS1 | OKEH01461 | Platonov, ME, Borovjagin, AV, Kaverina, N., Xiao, T., Kadagidze,Z., Lesniak, M. Baryshnikova, M. and I. Ulasova. KISS1 tumor suppressor restricts angiogenesis of breast cancer brain metastases and sensitizes them to oncolytic virotherapy in vitro. Cancer Letters. 2018 Mar 28; 417:75-88. 29269086 | 29269086 |
| 1431 | KIT | OAEE00056 | Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 66, 879-888 (2018). 30004288 | 30004288 |
| 1432 | KL | OKEH01597 | Inverse sex-based expression profiles of PTEN and Klotho in mice. Sci Rep. 10, 20189 (2020). 33214645 | 33214645 |
| 1433 | KL | OKEH01598 | Moderate aerobic exercise training decreases middle-aged induced pathologic cardiac hypertrophy by improving Klotho expression, MAPK signaling pathway, and oxidative stress status in Wistar rats. Iran J Basic Med Sci. 21, 911-919 (2018). 30524691 | 30524691 |
| 1434 | KLB | ARP53325_P050 | Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.EBioMedicine10418182NULLAugust2022 | 35908416 |
| 1435 | KLF11 | ARP38365_P050 | Chronic Social Stress and Ethanol Increase Expression of KLF11, a Cell Death Mediator, in Rat Brain. Neurotox Res. 28, 18-31 (2015). 25739536 | 25739536 |
| 1436 | KLF2 | ARP32760_P050 | Yamada, T., Park, C. S., Mamonkin, M. & Lacorazza, H. D. Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2. Nat. Immunol. 10, 618-26 (2009). 19412182 | 19412182 |
| 1437 | KLF4 | ARP38430_P050 | BMP- and TGFβ-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina. Glia. 65, 1640-1655 (2017). 28703293 | 28703293 |
| 1438 | Klf4 | OAAD00376 | Luz-Madrigal, A. et al. Reprogramming of the chick retinal pigmented epithelium after retinal injury. BMC Biol. 12, 28 (2014). 24742279 | 24742279 |
| 1439 | KLF4 | OKCD00271 | KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells. PLoS One. 10, e0130341 (2015). 26075898 | 26075898 |
| 1440 | KLF4 | ARP37039_P050 | Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of Müller Glia-Derived Progenitor Cells in the Avian Retina. Stem Cells 2018 3 36 392-405 29193451 | 29193451 |
| 1441 | KLF8 | ARP31533_P050 | Fu, W.-J. et al. Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo. J. Cancer Res. Clin. Oncol. 136, 1255-65 (2010). 20182889 | 20182889 |
| 1442 | KLF8 | ARP31533_P050 | Li, J.-C. et al. Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma. Gastroenterology 139, 2146-2157.e12 (2010). 20728449 | 20728449 |
| 1443 | KLF8 | ARP31533_P050 | Han, S. et al. Krüppel‑like factor expression and correlation with FAK, MMP‑9 and E‑cadherin expression in hepatocellular carcinoma. Mol. Med. Rep. 8, 81-8 (2013). 23670717 | 23670717 |
| 1444 | KLF8 | ARP31533_P050 | KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. Oncotarget. 6, 25402-17 (2015). 26320172 | 26320172 |
| 1445 | KLHL41 | ARP38732_T100 | A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. Skelet Muscle. 3, 3 (2013). 23414517 | 23414517 |
| 1446 | KLHL5 | ARP39220_P050 | Nagalla, S. et al. Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood 117, 5189-97 (2011). 21415270 | 21415270 |
| 1447 | KLK3 | ARP41879_P050 | Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip. Biosens Bioelectron. 77, 491-8 (2016). 26457734 | 26457734 |
| 1448 | KMO | OAAB05255 | Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas. Cells. 10, NULL (2021) 34440798 | 34440798 |
| 1449 | KMO | OKEH05543 | Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice. iScience 2022 5 25 104241 35494242 | 35494242 |
| 1450 | KNG1 | ARP45680_P050 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1451 | KRAS | OACA01930 | Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS. J Clin Med. 8, (2019). 31635338 | 31635338 |
| 1452 | L1CAM | ARP56677_P050 | Increased plasmin-mediated proteolysis of L1CAM in a mouse model of idiopathic normal pressure hydrocephalus. Proc Natl Acad Sci U S A 2021 33 118 NULL 34380733 | 34380733 |
| 1453 | LAMB1 | ARP48567_P050 | Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci. 1933719117697127 (2017). 28299992 | 28299992 |
| 1454 | LAMP1 | OAAB13754 | Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling. Autophagy. 13, 1855-1869 (2017). 28825851 | 28825851 |
| 1455 | LAMP2 | OAAB06712 | Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling. Autophagy. 13, 1855-1869 (2017). 28825851 | 28825851 |
| 1456 | LAMP2 | OAAB06711 | Lysosomes, autophagosomes and Alzheimer pathology in dementia with Lewy body disease.NeuropathologyNULLNULLNULLMay2018 | 29748975 |
| 1457 | LAMP3 | ARP41598_P050 | Lysosome-associated membrane glycoprotein 3 is involved in influenza A virus replication in human lung epithelial (A549) cells. Virol J. 8, 384 (2011). 21810281 | 21810281 |
| 1458 | LAMP3 | ARP41598_P050 | Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease. Brain. 137, 834-48 (2014). 24477431 | 24477431 |
| 1459 | LAPTM4B | ARP62852_P050 | LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Nat Commun. 6, 7250 (2015). 25998567 | 25998567 |
| 1460 | LARP7 | ARP40847_P050 | Muniz, L., Egloff, S. & Kiss, T. RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP. Nucleic Acids Res. 41, 4686-98 (2013). 23471002 | 23471002 |
| 1461 | LARP7 | ARP40847_P050 | The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J. 36, 934-948 (2017). 28254838 | 28254838 |
| 1462 | LARP7 | ARP40847_P050 | The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 7, (2018). 29845934 | 29845934 |
| 1463 | l-ASNase | OOPA00130 | Song, J. H. et al. Analysis of gene profiles involved in the enhancement of all-trans retinoic acid-induced HL-60 cell differentiation by sesquiterpene lactones identifies asparagine synthetase as a novel target for differentiation-inducing therapy. Int. J. Oncol. 44, 970-6 (2014). 24398846 | 24398846 |
| 1464 | LBP | ARP41546_P050 | Seasonal heat load is more potent than the degree of body weight loss in dysregulating immune function by reducing white blood cell populations and increasing inflammation in Holstein dairy cows. J Dairy Sci. 103, 10809-10822 (2020). 32896401 | 32896401 |
| 1465 | LBP | OKBB00573 | Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice. Aging (Albany NY). 10, 930-950 (2018). 29769431 | 29769431 |
| 1466 | LBP | OKCA02041 | Seasonal heat load is more potent than the degree of body weight loss in dysregulating immune function by reducing white blood cell populations and increasing inflammation in Holstein dairy cows. J Dairy Sci. 103, 10809-10822 (2020). 32896401 | 32896401 |
| 1467 | LC3-II | OAAB13483 | NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell. Toxicon. 121, 86-97 (2016). 27527270 | 27527270 |
| 1468 | LCAT | ARP41695_T100 | Surin, B. et al. LG3 fragment of endorepellin is a possible biomarker of severity in IgA nephropathy. Proteomics 13, 142-52 (2013). 23166663 | 23166663 |
| 1469 | LEP | ARP41697_P050 | Leptin in the canine uterus and placenta: possible implications in pregnancy. Reprod Biol Endocrinol. 13, 13 (2015). 25871422 | 25871422 |
| 1470 | LEP | ARP41698_P050 | Proteomic Analysis of Plasma Reveals Fat Mass Influences Cancer-Related Pathways in Healthy Humans Fed Controlled Diets Differing in Glycemic Load. Cancer Prev Res (Phila). 12, 567-578 (2019). 31266826 | 31266826 |
| 1471 | LEPTIN | ARP41697_P050 | Different expression of leptin and IGF1 in the adult and prepubertal testis in dogs. Reprod. Domest. Anim. 52 Suppl 2, 187-192 (2017). 28101891 | 28101891 |
| 1472 | LEPTIN | OKAA00022-96W | Association between obstructive sleep apnea severity and endothelial dysfunction in patients with type 2 diabetes. Cardiovasc Diabetol. 16, 39 (2017). 28327146 | 28327146 |
| 1473 | LETM2 | ARP52722_P050 | Dutt, A. et al. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS One 6, e20351 (2011). 21666749 | 21666749 |
| 1474 | LFT | OKEH02822 | PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 2021 5 320 L845-L879 33655758 | 33655758 |
| 1475 | LGALS3 | ARP54688_P050 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
| 1476 | LHCGR | ARP61025_P050 | Novel functions of the luteinizing hormone/chorionic gonadotropin receptor in prostate cancer cells and patients. PLoS One. 15, e0238814 (2020) 32881970 | 32881970 |
| 1477 | LHFPL5 | OAAB00424 | Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15. PLoS One. 12, e0185285 (2017). 29069081 | 29069081 |
| 1478 | LHFPL5 | OAAB00424 | Localization of TMC1 and LHFPL5 in auditory hair cells in neonatal and adult mice. FASEB J. 33, 6838-6851 (2019) 30808210 | 30808210 |
| 1479 | LHX6 | ARP32185_P050 | Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis. Cell Death Differ 2022 NULL NULL NULL 35273362 | 35273362 |
| 1480 | LIPE | OAAF00742 | Shao-Wei Lu, et al. IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models. 4611 (2020). 32929072 | 32929072 |
| 1481 | LIPOPOLYSACCHARIDE | OKEH02594 | Rhubarb Enema Improved Colon Mucosal Barrier Injury in 5/6 Nephrectomy Rats May Associate With Gut Microbiota Modification. Front Pharmacol. 11, 1092 (2020). 32848732 | 32848732 |
| 1482 | Lipoteichoic acid | OKEH02591 | Saccharomyces cerevisiae fermentation products reduce bacterial endotoxin concentrations and inflammation during grain-based subacute ruminal acidosis in lactating dairy cows. J Dairy Sci. (2022). 34998547 | 34998547 |
| 1483 | LMNB1 | ARP46137_P050 | Dynamic association of NUP98 with the human genome. PLoS Genet. 9, e1003308 (2013) 23468646 | 23468646 |
| 1484 | LMNB2 | ARP46356_P050 | The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing. Genes Dev. 29, 1224-38 (2015). 26080816 | 26080816 |
| 1485 | LOC100009097 | OASB00822 | Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis. Cell Rep. 25, 57-67.e5 (2018). 30282038 | 30282038 |
| 1486 | LOX1 | OACD05298 | Molecular mechanism of statin-mediated LOX-1 inhibition. Cell Cycle. 14, 1583-95 (2015). 25950192 | 25950192 |
| 1487 | LOX-1 | OABB00784 | Membrane Cholesterol Modulates LOX-1 Shedding in Endothelial Cells. PLoS ONE. 10, e0141270 (2015). 26495844 | 26495844 |
| 1488 | LOX15 | OAAB04977 | Starowicz, K. et al. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. PLoS One 8, e60040 (2013). 23573230 | 23573230 |
| 1489 | LOXL1 | ARP54780_P050 | Ohmura, H. et al. Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice. Hypertens. Res. 35, 1063-8 (2012). 22763477 | 22763477 |
| 1490 | LPA | OKCD06889 | VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly. Arterioscler Thromb Vasc Biol 2020 3 40 819-829 32078365 | 32078365 |
| 1491 | LPL | OKCD06285 | A novel NanoBiT-based assay monitors the interaction between lipoprotein lipase and GPIHBP1 in real time. J Lipid Res. 61, 546-559 (2020). 32029511 | 32029511 |
| 1492 | LRG1 | ARP52475_P050 | O’Hanlon, T. P. et al. Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases. Arthritis Res. Ther. 13, R181 (2011). 22044644 | 22044644 |
| 1493 | LRP1 | ARP58562_P050 | Behl, M., Zhang, Y., Monnot, A. D., Jiang, W. & Zheng, W. Increased beta-amyloid levels in the choroid plexus following lead exposure and the involvement of low-density lipoprotein receptor protein-1. Toxicol. Appl. Pharmacol. 240, 245-54 (2009). 19501112 | 19501112 |
| 1494 | LRP1 | ARP58562_P050 | Gu, H. et al. Lead exposure increases levels of beta-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice. Neurosci. Lett. 490, 16-20 (2011). 21167913 | 21167913 |
| 1495 | LRP1 | ARP58562_P050 | Hentschke, M. R. et al. Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype. J. Lipid Res. 54, 2658-64 (2013). 23898049 | 23898049 |
| 1496 | LRP1 | OKEH01469 | Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. Nat Commun. 9, 5191 (2018). 30518764 | 30518764 |
| 1497 | LRPPRC | ARP41093_P050 | DHX9 regulates production of hepatitis B virus-derived circular RNA and viral protein levels. Oncotarget. 9, 20953-20964 (2018). 29765512 | 29765512 |
| 1498 | LRRC50 | ARP53358_P050 | Yang, L. et al. Knockdown of PPAR d gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model. PLoS One 8, e60715 (2013). 23593291 | 23593291 |
| 1499 | LRRC50 | ARP53359_P050 | Basten, S. G. et al. Mutations in LRRC50 predispose zebrafish and humans to seminomas. PLoS Genet. 9, e1003384 (2013). 23599692 | 23599692 |
| 1500 | LRRFIP1 | ARP38506_P050 | Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation. Antioxidants (Basel). 9, (2020). 33265962 | 33265962 |
| 1501 | LTC4S | ARP49035_T100 | Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease. J. Exp. Med. 212, 1487-95 (2015). 26304964 | 26304964 |
| 1502 | LTN1 | OAAB11604 | Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex. Nat Commun. 8, 15730 (2017). 28589942 | 28589942 |
| 1503 | LXRbeta | ARP33481_P050 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
| 1504 | LYPD6 | ARP53451_P050 | Functional interaction between Lypd6 and nicotinic acetylcholine receptors. J. Neurochem. 138, 806-20 (2016). 27344019 | 27344019 |
| 1505 | LYPD6 | ARP53451_P050 | Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease. Neurobiol Aging. 36, 1629-1638 (2015) 25680266 | 25680266 |
| 1506 | LYRM4 | ARP57407_P050 | Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 177, 1507-1521.e16 (2019). 31031004 | 31031004 |
| 1507 | LYZ | OKCD01349 | PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 2021 5 320 L845-L879 33655758 | 33655758 |
| 1508 | LYZL6 | ARP53746_P050 | Characterisation of Lyzls in mice and antibacterial properties of human LYZL6. Asian J Androl. 15, 824-30 (2013). 24013621 | 24013621 |
| 1509 | LZTFL1 | ARP48390_T100 | Sakurai, T. et al. Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training. Biochem. Biophys. Res. Commun. 416, 125-9 (2011). 22093827 | 22093827 |
| 1510 | MAFA | ARP47760_P050 | Molecular and genetic regulation of pig pancreatic islet cell development. Development. 147, NULL (2020). 32108026 | 32108026 |
| 1511 | MAFA | ARP47760_P050 | Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes. Mol Metab. 54, 101330 (2021). 34500108 | 34500108 |
| 1512 | MAFA | ARP52972_P050 | Molecular and genetic regulation of pig pancreatic islet cell development. Development 2020 NULL NULL NULL 34004773 | 34004773 |
| 1513 | MAGI2 | ARP61404_P050 | Corticosteroid treatment exacerbates nephrotic syndrome in a zebrafish model of magi2a knockout. Kidney Int. 95, 1079-1090 (2019). 31010479 | 31010479 |
| 1514 | MANF | OKCD02709 | MANF Promotes Diabetic Corneal Epithelial Wound Healing and Nerve Regeneration by Attenuating Hyperglycemia-Induced Endoplasmic Reticulum Stress. Diabetes. 69, 1264-1278 (2020). 32312869 | 32312869 |
| 1515 | Mannose | OKEH02595 | Elevated Serum Mannose Levels as a Marker of Polycystic Ovary Syndrome. Front Endocrinol (Lausanne). 10, 711 (2019). 31681178 | 31681178 |
| 1516 | MAOA | OKEH02825 | Association of Monoamine Oxidase A with Tumor Burden and Castration Resistance in Prostate Cancer. Curr Ther Res Clin Exp. 93, 100610 (2020). 33245296 | 33245296 |
| 1517 | MAOA | OKEH02825 | The Hunger Games: Aggregatibacter actinomycetemcomitans Exploits Human Neutrophils As an Epinephrine Source for Survival. Front Immunol. 12, 707096 (2021) 34456916 | 34456916 |
| 1518 | MAP1LC3A | ARP51335_P050 | Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy. Br J Pharmacol. 177, 1434-1452 (2020). 31658364 | 31658364 |
| 1519 | MAP1LC3A | OKEH01675 | Unraveling the therapeutic potential of GANT61/Dactolisib combination as a novel prostate cancer modality. Med Oncol 2022 10 39 143 35834137 | 35834137 |
| 1520 | MAP2K | ARP41757_P050 | Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model. Endocrinology 2017 3 158 560-577 28359089 | 28359089 |
| 1521 | MAP2K7 | OAAF05547 | Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 7, 10592 (2016). 26882989 | 26882989 |
| 1522 | MAP2K7 | OAAF05547 | Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. Nat. Med. 23, 439-449 (2017). 28218919 | 28218919 |
| 1523 | MAP2K7 | ARP51904_P050 | Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis. Nat Commun 2022 1 13 669 35115556 | 35115556 |
| 1524 | MAP3K7IP2 | ARP32402_P050 | Thienpont, B. et al. Haploinsufficiency of TAB2 causes congenital heart defects in humans. Am. J. Hum. Genet. 86, 839-49 (2010). 20493459 | 20493459 |
| 1525 | March5 | ARP43232_P050 | Cilenti, L. et al. Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy. Biochim. Biophys. Acta 1843, 1295-307 (2014). 24709290 | 24709290 |
| 1526 | MARCKSL1 | ARP64193_P050 | Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One. 8, e58456 (2013). 23520512 | 23520512 |
| 1527 | MARVELD3 | ARP44715_P050 | α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function. Exp Neurol. 285, 72-81 (2016) 27632900 | 27632900 |
| 1528 | MAT1A | ARP41399_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 1529 | MATN2 | ARP57667_P050 | Szalai, E. et al. Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol. Vis. 18, 1927-36 (2012). 22876117 | 22876117 |
| 1530 | MATN2 | ARP57667_P050 | Extracellular matrix changes in corneal opacification vary depending on etiology. Mol Vis. 27, 26-36 (2021). 33633437 | 33633437 |
| 1531 | MATR3 | ARP40922_T100 | Valencia, C. A., Ju, W. & Liu, R. Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases. Biochem. Biophys. Res. Commun. 361, 281-6 (2007). 17658460 | 17658460 |
| 1532 | MATR3 | ARP40922_T100 | Kula, A. et al. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology 8, 60 (2011). 21771346 | 21771346 |
| 1533 | MATR3 | ARP40922_T100 | Kula, A., Gharu, L. & Marcello, A. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. Virology 435, 329-40 (2013). 23158102 | 23158102 |
| 1534 | MAZ | ARP34161_P050 | Himeda, C. L., Ranish, J. A. & Hauschka, S. D. Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes. Mol. Cell. Biol. 28, 6521-35 (2008). 18710939 | 18710939 |
| 1535 | MAZ | ARP38146_P050 | Smits, M. et al. Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. FASEB J. 26, 2639-47 (2012). 22415301 | 22415301 |
| 1536 | MBD1 | ARP32012_P050 | Jungwirth, M., Dear, M. L., Brown, P., Holbrook, K. & Goodchild, R. Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum. Mol. Genet. 19, 888-900 (2010). 20034025 | 20034025 |
| 1537 | MBD2 | ARP32485_P050 | Jungwirth, M., Dear, M. L., Brown, P., Holbrook, K. & Goodchild, R. Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum. Mol. Genet. 19, 888-900 (2010). 20034025 | 20034025 |
| 1538 | MBD4 | ARP34797_P050 | DNMT1 cooperates with MBD4 to inhibit the expression of Glucocorticoid-induced TNFR-related protein in human T cells. FEBS Lett. 591, 1929-1939 (2017). 28542810 | 28542810 |
| 1539 | MBLAC1 | ARP70842_P050 | Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease. Elife. 7, (2018). 30507380 | 30507380 |
| 1540 | MBNL1 | ARP41227_P050 | Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev. Biol. 15, 36 (2015). 26472242 | 26472242 |
| 1541 | MBOAT7 | ARP49811_T100 | Lack of evidence supporting a role of TMC4-rs641738 missense variant-MBOAT7- intergenic downstream variant-in the Susceptibility to Nonalcoholic Fatty Liver Disease. Sci Rep. 8, 5097 (2018). 29572551 | 29572551 |
| 1542 | MBOAT7 | OAAB15200 | Blanchard, H. et al. iPLA2beta knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology. Neurochem. Res. 39, 1522-32 (2014). 24919816 | 24919816 |
| 1543 | MBP | OABB00147 | Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions. PLoS ONE. 11, e0148238 (2016). 26829325 | 26829325 |
| 1544 | MBP | OKCD02716 | Teruya, Shihono et al. Bordetella Dermonecrotic Toxin Is a Neurotropic Virulence Factor That Uses CaV3.1 as the Cell Surface Receptor. mBio. 2020 Mar-Apr; 11(2): e03146-19. 32209694 | 32209694 |
| 1545 | mCherry-Tag | OAAB02551 | Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers. Front Oncol 2022 NULL 12 906494 35814364 | 35814364 |
| 1546 | MCM2 | ARP36647_T100 | Rizwani, W., Alexandrow, M. & Chellappan, S. Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication. Cell Cycle 8, 1621-9 (2009). 19377303 | 19377303 |
| 1547 | MCM8 | ARP36668_P050 | Ono, A. et al. Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues. Hum. Pathol. 40, 41-9 (2009). 18755499 | 18755499 |
| 1548 | MCPT2 | OKEH02490 | Reyes-Pavon, Diana et al. Protective Effect of Glycomacropeptide on Food Allergy with Gastrointestinal Manifestations in a Rat Model through Down-Regulation of Type 2 Immune Response. Nutrients. 2020 Sep 25;12(10):2942. 32992996 | 32992996 |
| 1549 | MCPT4 | OKWB00279 | Nonlethal Plasmodium yoelii Infection Drives Complex Patterns of Th2-Type Host Immunity and Mast Cell-Dependent Bacteremia. Infect Immun. 88, NULL (2020). 32958528 | 32958528 |
| 1550 | MCUR1 | ARP44777_P050 | Mallilankaraman, K. et al. MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism. Nat. Cell Biol. 14, 1336-43 (2012). 23178883 | 23178883 |
| 1551 | MCUR1 | ARP44777_P050 | Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Sci Signal. 8, ra23 (2015). 25737585 | 25737585 |
| 1552 | MDH1 | ARP48283_P050 | Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish. Mol Biol Evol. 37, 2887-2899 (2020) 32437540 | 32437540 |
| 1553 | MDH1 | ARP48284_T100 | Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). 23704975 | 23704975 |
| 1554 | MDH1 | ARP48284_T100 | Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo. Neuropsychopharmacology. 41, 1751-8 (2016). 26567514 | 26567514 |
| 1555 | MDH2 | ARP48286_T100 | Freund, D. M., Prenni, J. E. & Curthoys, N. P. Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis. Am. J. Physiol. Renal Physiol. 304, F145-55 (2013). 23136003 | 23136003 |
| 1556 | MDH2 | ARP48286_T100 | Povlsen, J. A. et al. Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One 8, e64093 (2013). 23704975 | 23704975 |
| 1557 | MDH2 | ARP32553_T100 | 2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics 2011 8 11 1413-28 21360670 | 21360670 |
| 1558 | MDM4 | AVARP06007_P050 | Schlaeger, C. et al. Etiology-dependent molecular mechanisms in human hepatocarcinogenesis. Hepatology 47, 511-20 (2008). 18161050 | 18161050 |
| 1559 | ME3 | ARP48511_P050 | Hypoxia further exacerbates woody breast myopathy in broilers via alteration of satellite cell fate. Poult Sci. 100, 101167 (2021) 34091348 | 34091348 |
| 1560 | MeCP2 | ARP43584_T100 | Jungwirth, M., Dear, M. L., Brown, P., Holbrook, K. & Goodchild, R. Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum. Mol. Genet. 19, 888-900 (2010). 20034025 | 20034025 |
| 1561 | MED17 | ARP34192_P050 | DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes. Nat Commun. 5, 4263 (2014). 24968874 | 24968874 |
| 1562 | MED17 | ARP34192_P050 | Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor. J Clin Invest. 125, 183-93 (2015). 25437875 | 25437875 |
| 1563 | MED19 | ARP55595_P050 | A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. Oncogene. 36, 446-457 (2017). 27375018 | 27375018 |
| 1564 | MED25 | ARP50698_P050 | Sela, D. et al. Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6a. J. Biol. Chem. 288, 26179-87 (2013). 23864652 | 23864652 |
| 1565 | MED25 | ARP50699_P050 | ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain. J Mol Biol. 429, 2975-2995 (2017). 28728983 | 28728983 |
| 1566 | MED25 | OAAB00209 | Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. Nucleic Acids Res. 44, 7568-79 (2016). 27166374 | 27166374 |
| 1567 | MEF2C | ARP37342_T100 | Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864 | 18772864 |
| 1568 | MEF2C | ARP37342_T100 | Lombardi, R. et al. Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ. Res. 104, 1076-84 (2009). 19359597 | 19359597 |
| 1569 | MEF2C | ARP37342_T100 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20335662 | 20335662 |
| 1570 | MEF2C | ARP37342_T100 | Escher, P., Schorderet, D. F. & Cottet, S. Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice. Invest. Ophthalmol. Vis. Sci. 52, 5933-40 (2011). 21715356 | 21715356 |
| 1571 | MEF2C | ARP37342_T100 | Inagawa, K. et al. Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5. Circ. Res. 111, 1147-56 (2012). 22931955 | 22931955 |
| 1572 | MEF2C | ARP37342_T100 | Law, S. K. et al. Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem cells. Int. J. Cardiol. 168, 3458-72 (2013). 23706318 | 23706318 |
| 1573 | MEF2C | ARP37342_T100 | Targeting the histone demethylase LSD1 prevents cardiomyopathy in a mouse model of laminopathy. J Clin Invest. 131 (2021). 33393499 | 33393499 |
| 1574 | MEF2C | OAGA02537 | MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS. Bone Res. 9, 4 (2021). 33424022 | 33424022 |
| 1575 | MEIS2 | ARP34683_P050 | Raj R Bhanvadia, et al. MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. 3668-3680 (2018). 29716922 | 29716922 |
| 1576 | MEIS2 | ARP34684_T100 | Jackson, B. et al. TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier. J. Cell Sci. 124, 1681-90 (2011). 21511732 | 21511732 |
| 1577 | Melatonin | OKEH02566 | Light at night disrupts diel patterns of cytokine gene expression and endocrine profiles in zebra finch (Taeniopygia guttata). Sci Rep. 9, 15833 (2019). 31676761 | 31676761 |
| 1578 | MELATONIN | OKEH02566 | Measuring melatonin by immunoassay. J Pineal Res. 69, e12657 (2020). 32281677 | 32281677 |
| 1579 | MELATONIN | OKEH02566 | PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance. Commun Biol. 3, 628 (2020). 33127955 | 33127955 |
| 1580 | MER | OAAF00456 | Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. Cell Commun. Signal. 14, 19 (2016). 27595981 | 27595981 |
| 1581 | MERLIN | ARP63180_P050 | Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons. Cell. Mol. Neurobiol. (2017). 28236056 | 28236056 |
| 1582 | MESP1 | ARP39374_P050 | Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration. Biomaterials. 73, 51-9 (2015). 26398309 | 26398309 |
| 1583 | MESP1 | ARP39374_P050 | Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. J Tissue Eng Regen Med. (2016). 27943600 | 27943600 |
| 1584 | MESP1 | ARP39374_P050 | SWI/SNF Component BAF250a Coordinates OCT4 and WNT Signaling Pathway to Control Cardiac Lineage Differentiation. Front Cell Dev Biol. 7, 358 (2020). 32039194 | 32039194 |
| 1585 | MESP1 | ARP39374_P050 | Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair. Theranostics. 10, 6898-6914 (2020). 32550911 | 32550911 |
| 1586 | MESP1 | OAAB09387 | Coupling switch of P2Y-IP3 receptors mediates differential Ca(2+) signaling in human embryonic stem cells and derived cardiovascular progenitor cells. Purinergic Signal. 12, 465-78 (2016). 27098757 | 27098757 |
| 1587 | MESP1 | OAAB09387 | Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations. Stem Cell Reports. 9, 366-380 (2017). 28506532 | 28506532 |
| 1588 | MESP1/2 | ARP39374_P050 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20335662 | 20335662 |
| 1589 | MESP1/2 | ARP39374_P050 | Cao, N. et al. Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cell Res. 23, 1119-32 (2013). 23896987 | 23896987 |
| 1590 | MESP2 | ARP36921_T100 | Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864 | 18772864 |
| 1591 | METRNL | OKEH00577 | Effects of electrical stimulation-induced resistance exercise training on white and brown adipose tissues and plasma meteorin-like concentration in rats. Physiol Rep. 8, e14540 (2020). 32812347 | 32812347 |
| 1592 | METTL14 | ARP50652_P050 | Acute Deletion of METTL14 in β-Cells of Adult Mice Results in Glucose Intolerance. Endocrinology. 160, 2388-2394 (2019). 31369074 | 31369074 |
| 1593 | METTL3 | ARP34591_P050 | Neural glycoprotein M6a is released in extracellular vesicles and modulated by chronic stressors in blood. Sci Rep. 7, 9788 (2017). 28851962 | 28851962 |
| 1594 | METTL3 | ARP39390_T100 | N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 55, 737-753.e7 (2020). 33220174 | 33220174 |
| 1595 | MFN1 | ARP57702_P050 | Papanicolaou, K. N. et al. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol. Cell. Biol. 31, 1309-28 (2011). 21245373 | 21245373 |
| 1596 | MFN1 | ARP57702_P050 | Bonala, S. et al. Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity. Mol. Endocrinol. 27, 1518-35 (2013). 23927930 | 23927930 |
| 1597 | MFN2 | ARP42420_P050 | Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIa to induce mitochondrial fragmentation. Sci Rep. 6, 23464 (2016). 27010100 | 27010100 |
| 1598 | MFN2 | ARP89255_P050 | Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2021, 6924251 (2021). 34691359 | 34691359 |
| 1599 | MFSD12 | ARP44958_P050 | A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Nat Commun. 10, 358 (2019). 30664655 | 30664655 |
| 1600 | MIC10 | ARP44801_P050 | Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature. 538, 123-126 (2016). 27626371 | 27626371 |
| 1601 | Mif4GD | ARP40950_T100 | Okada, K. et al. Expression analysis of MIF4GD in the rat testis. J. Reprod. Dev. 57, 256-61 (2011). 21157122 | 21157122 |
| 1602 | MINOS1 | ARP44801_P050 | Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit. Eur J Hum Genet. 24, 1778-1782 (2016). 27485409 | 27485409 |
| 1603 | MINOS1 | ARP44801_P050 | FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function. J Cell Biol. 218, 97-111 (2019). 30404948 | 30404948 |
| 1604 | MINOS1 | ARP44801_P050 | Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I. Cell Rep. 31, 107541 (2020). 32320651 | 32320651 |
| 1605 | MINOS1 | ARP44801_P050 | A novel homozygous variant in MICOS13/QIL1 causes hepato-encephalopathy with mitochondrial DNA depletion syndrome. Mol Genet Genomic Med. 8, e1427 (2020). 32749073 | 32749073 |
| 1606 | MINOS1 | ARP32173_P050 | QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife 2016 NULL 5 NULL 27623147 | 27623147 |
| 1607 | MITF | ARP31212_P050 | Schartl, M. et al. A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies. J. Invest. Dermatol. 130, 249-58 (2010). 19609310 | 19609310 |
| 1608 | MITF | ARP37978_P050 | BDNF rs6265 methylation and genotype interact on risk for schizophrenia. Epigenetics. 11, 11-23 (2016). 26889735 | 26889735 |
| 1609 | MIWI | ARP41339_P050 | Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. J. Cell. Sci. 130, 1463-1474 (2017). 28254886 | 28254886 |
| 1610 | MKI67 | OAAF01852 | Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure. Stem Cell Res Ther. 8, 70 (2017). 28320485 | 28320485 |
| 1611 | MKL1 | ARP37504_T100 | Mechanism of irradiation-induced mammary cancer metastasis: A role for SAP-dependent Mkl1 signaling. Mol Oncol. 9, 1510-27 (2015). 25999144 | 25999144 |
| 1612 | MKL1 | ARP37504_T100 | Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep. 32, 108050 (2020). 32814053 | 32814053 |
| 1613 | MLKL | OAAB10571 | MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis. Proc Natl Acad Sci U S A. 114, E7450-E7459 (2017). 28827318 | 28827318 |
| 1614 | MLKL | OAAB10571 | RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1γ promote apoptosis and necroptosis. Nat Commun. 12, 7067 (2021). 34862394 | 34862394 |
| 1615 | MLKL | OKEH05350 | Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis Pathway. Int J Mol Sci. 22, NULL (2021) 34445504 | 34445504 |
| 1616 | MLKL | OKEH03401 | Persistently Elevated Plasma Levels of RIPK3, MLKL, HMGB1, and RIPK1 in COVID-19 ICU Patients. Am J Respir Cell Mol Biol 2022 NULL NULL NULL 35385375 | 35385375 |
| 1617 | MMP10 | OAAF01865 | Inside the Thrombus: Association of Hemostatic Parameters With Outcomes in Large Vessel Stroke Patients. Front Neurol. 12, 599498 (2021) 33692737 | 33692737 |
| 1618 | MMP10 | OAAI00209 | Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation.BiomedicinesNULL107June2022 | 35884862 |
| 1619 | MMP13 | ARP56350_P050 | Park, Y. S. et al. Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells. AAPS J. 15, 367-76 (2013). 23250670 | 23250670 |
| 1620 | MMP13 | ARP56350_P050 | Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in models of cartilage degradation. J Orthop Res. (2020) 32725904 | 32725904 |
| 1621 | MMP13 | ARP56350_P050 | Intra-Articular Administration of Cramp into Mouse Knee Joint Exacerbates Experimental Osteoarthritis Progression. Int J Mol Sci. 22 (2021). 33810460 | 33810460 |
| 1622 | MMP13 | ARP56350_P050 | Alleviation of Murine Osteoarthritis by Cartilage-Specific Deletion of IκBζ.Arthritis Rheumatol1440-1449709September2018 | 29604191 |
| 1623 | MMP2 | AVARP20016_T100 | TNF-a promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts. Cell Oncol (Dordr). 39, 353-63 (2016). 27042827 | 27042827 |
| 1624 | MMP2 | AVARP20016_T100 | Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci. 1933719117697127 (2017). 28299992 | 28299992 |
| 1625 | MMP3 | ARP42042_P050 | Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1β and tumor necrosis factor-α in models of cartilage degradation. J Orthop Res. (2020) 32725904 | 32725904 |
| 1626 | MMP3 | OAAF01874 | Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis. J Pain Res. 10, 1973-1989 (2017). 28860852 | 28860852 |
| 1627 | MMP7 | OKCD05950 | An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury. EMBO Rep. 22, e52785 (2021). 34224201 | 34224201 |
| 1628 | MMP9 | ARP33090_T100 | Gotschy, A. et al. Local arterial stiffening assessed by MRI precedes atherosclerotic plaque formation. Circ. Cardiovasc. Imaging 6, 916-23 (2013). 24100044 | 24100044 |
| 1629 | MMP9 | ARP33090_T100 | Li, L. et al. DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling. PLoS One 9, e91509 (2014). 24621612 | 24621612 |
| 1630 | MMP9 | ARP33090_T100 | Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci. 1933719117697127 (2017). 28299992 | 28299992 |
| 1631 | MMP9 | OKAA00024-96W | Hepatoprotective and anti-tumor effects of targeting MMP-9 in hepatocellular carcinoma and its relation to vascular invasion Markers. Clinical & Experimental Metastasis. 32, 479-493 (2015). 25999065 | 25999065 |
| 1632 | MMP9 | OKCD06482 | Blockade of recombinant human IL-6 by tocilizumab suppresses matrix metalloproteinase-9 production in the C28/I2 immortalized human chondrocyte cell line. 304-310 (2016). 26753098 | 26753098 |
| 1633 | MMP-9 | ARP33090_T100 | Zhang, J., Jiang, W. & Zuo, Z. Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. Neuroscience 261, 1-10 (2014). 24365462 | 24365462 |
| 1634 | MMP-9 | ARP33090_T100 | Deng, J., Zhang, J., Feng, C., Xiong, L. & Zuo, Z. Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice. Cardiovasc. Res. 103, 473-84 (2014). 24935427 | 24935427 |
| 1635 | MMP-9 | ARP33090_T100 | Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine. Fundam Clin Pharmacol. 30, 47-57 (2016). 26501493 | 26501493 |
| 1636 | MOG | OAPA00088 | Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis with Candida utilis Expressing the Immunogenic MOG35-55 Peptide. PLoS ONE. 11, e0155082 (2016). 27159446 | 27159446 |
| 1637 | MPL | OKCD07412 | Rebound Thrombocytosis after Induction Chemotherapy is a Strong Biomarker for Favorable Outcome in AML Patients. Hemasphere. 3, e180 (2019). 31723819 | 31723819 |
| 1638 | MPO | OKEH02834 | Topical Neck Cooling Prolongs Survival of Rats with Intra-Abdominal Feculent Sepsis by Activation of the Vagus Nerve. Int J Mol Sci 2021 18 22 NULL 34575994 | 34575994 |
| 1639 | MPST | ARP48394_P050 | Histamine-Induced Dilation of Isolated Porcine Retinal Arterioles: Role of Endothelium-Derived Hyperpolarizing Factor. Invest. Ophthalmol. Vis. Sci. 57, 4791-8 (2016). 27618417 | 27618417 |
| 1640 | MPST | ARP48394_P050 | Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice. Invest. Ophthalmol. Vis. Sci. 58, 1954-1963 (2017). 28384716 | 28384716 |
| 1641 | MRAP | OAAB06581 | Exome-based investigation of the genetic basis of human pigmentary glaucoma. BMC Genomics. 22, 477 (2021) 34174832 | 34174832 |
| 1642 | MRC1 | OASA05048 | Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice. Gastroenterology. 154, 704-718.e10 (2018). 29079517 | 29079517 |
| 1643 | MRC1 | OASA05048 | NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute Pancreatitis. Gastroenterology. 158, 253-269.e14 (2020). 31593700 | 31593700 |
| 1644 | MRG15 | ARP32832_T100 | Xie, L. et al. KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 30, 1473-84 (2011). 21448134 | 21448134 |
| 1645 | MRO | ARP60588_P050 | The elusive MAESTRO gene: Its human reproductive tissue-specific expression pattern. PLoS ONE. 12, e0174873 (2017). 28406912 | 28406912 |
| 1646 | MRPL45 | ARP60476_P050 | Kotani, T., Akabane, S., Takeyasu, K., Ueda, T. & Takeuchi, N. Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes. Nucleic Acids Res. 41, 3713-22 (2013). 23396448 | 23396448 |
| 1647 | MRPS15 | ARP33299_P050 | Davies, S. M. K. et al. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583, 1853-8 (2009). 19427859 | 19427859 |
| 1648 | MSH2 | OAAF03051 | A rapidly growing human papillomavirus-positive oral tongue squamous cell carcinoma in a 21-year old female: A case report. Oncol Lett. 15, 7702-7706 (2018). 29849799 | 29849799 |
| 1649 | MSI2 | ARP41110_P050 | Cox, J. L. et al. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. PLoS One 8, e62857 (2013). 23667531 | 23667531 |
| 1650 | MSN | ARP63015_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 1651 | MSX1 | ARP31396_T100 | Mizokami, Y. et al. Expression of MSX1 in human normal pituitaries and pituitary adenomas. Endocr. Pathol. 19, 54-61 (2008). 18379900 | 18379900 |
| 1652 | MSX1 | ARP37094_T100 | Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Hum Mol Genet. 18, 248-60 (2009). 18930956 | 18930956 |
| 1653 | MTAP2 | OKCD02711 | Effects of HIV gp120 on Neuroinflammation in Immunodeficient vs. Immunocompetent States. J Neuroimmune Pharmacol 2021 2 16 437-453 32627098 | 32627098 |
| 1654 | MTf2 | ARP61983_P050 | Loss of PRC2 subunits primes lineage choice during exit of pluripotency. Nat Commun 2021 1 12 6985 34848733 | 34848733 |
| 1655 | Mthfd1 | OAAB01489 | Thangavel, M. et al. Proteomic analysis of rat prefrontal cortex after chronic valproate treatment. J. Neurosci. Res. 92, 927-36 (2014). 24692022 | 24692022 |
| 1656 | MTNR1B | ARP64072_P050 | Santoro, R. et al. Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation. Carcinogenesis 34, 1051-61 (2013). 23354312 | 23354312 |
| 1657 | MTNR1B | ARP64072_P050 | Stimulatory Effects of Melatonin on Porcine In Vitro Maturation Are Mediated by MT2 Receptor. Int J Mol Sci. 19, (2018). 29861447 | 29861447 |
| 1658 | MTNR1B | ARP64072_P050 | Melatonin enhances porcine embryo development via the Nrf2/ARE signaling pathway. J Mol Endocrinol. 63, 175-185 (2019). 31408847 | 31408847 |
| 1659 | MTNR1B | ARP64072_P050 | Melatonin-Nrf2 Signaling Activates Peroxisomal Activities in Porcine Cumulus Cell-Oocyte Complexes. Antioxidants (Basel). 9, (2020). 33153240 | 33153240 |
| 1660 | MTNR1B | OABF00337 | Melatonin Type 2 Receptor Activation Regulates Blue Light Exposure-Induced Mouse Corneal Epithelial Damage by Modulating Impaired Autophagy and Apoptosis.Int J Mol SciNULL2319September2022 | 36232639 |
| 1661 | MTPN | ARP52859_P050 | Nghiem, P. P. et al. Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogs. Am. J. Pathol. 183, 1411-24 (2013). 24160322 | 24160322 |
| 1662 | MTRR | ARP57657_P050 | Richard, E., Desviat, L. R., Ugarte, M. & Pérez, B. Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects. J. Cell. Biochem. 114, 183-91 (2013). 22887477 | 22887477 |
| 1663 | MTTP | ARP43618_P050 | In Vitro effect of DDE exposure on the regulation of lipid metabolism and secretion in McA-RH7777 hepatocytes: A potential role in dyslipidemia which may increase the risk of type 2 diabetes mellitus. Toxicol In Vitro. 37, 9-14 (2016). 27565303 | 27565303 |
| 1664 | MTTP | ARP43618_P050 | Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila. PLoS Genet. 13, e1006555 (2017). 28095410 | 28095410 |
| 1665 | MTUS1 | ARP44419_P050 | Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3. Oncotarget. 6, 43557-70 (2015). 26498358 | 26498358 |
| 1666 | MTUS1 | ARP43128_P050 | Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length. Cell Mol Life Sci 2021 4 78 1765-1779 32789689 | 32789689 |
| 1667 | MUC1 | ARP41446_T100 | Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway. Int J Clin Exp Pathol. 8, 4344-55 (2015). 26191126 | 26191126 |
| 1668 | MUC1 | ARP41446_T100 | GABA selectively increases mucin-1 expression in isolated pig jejunum. Genes Nutr. 10, 47 (2015). 26471792 | 26471792 |
| 1669 | Muc19 | OPPA00628 | Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands. Nat Commun 2022 1 13 3291 35672412 | 35672412 |
| 1670 | MUC2 | OKEH02839 | Docosahexaenoic and Eicosapentaenoic Acids Prevent Altered-Muc2 Secretion Induced by Palmitic Acid by Alleviating Endoplasmic Reticulum Stress in LS174T Goblet Cells. Nutrients. 11, (2019). 31514316 | 31514316 |
| 1671 | MUC3B | ARP58395_P050 | Song, J. S. et al. Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth. PLoS One 8, e61231 (2013). 23593441 | 23593441 |
| 1672 | MUC5AC | OKEH02840 | Exploiting the MUC5AC Antigen for Noninvasive Identification of Pancreatic Cancer. J Nucl Med 2021 10 62 1384-1390 33712530 | 33712530 |
| 1673 | MUC5B | OKEH02841 | Effects of oral lubrication on satiety, satiation and salivary biomarkers in model foods: A pilot study. Appetite 2021 NULL 165 105427 34051275 | 34051275 |
| 1674 | MUSK | OKEH07075 | Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS. Commun Biol. 4, 509 (2021) 33931719 | 33931719 |
| 1675 | MVP | OAGA01032 | Major Vault Protein, a Candidate Gene in 16p11.2 Microdeletion Syndrome, Is Required for the Homeostatic Regulation of Visual Cortical Plasticity. J Neurosci. 38, 3890-3900 (2018). 29540554 | 29540554 |
| 1676 | MX1 | ARP46077_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 1677 | MYBBP1A | ARP37224_T100 | Zheng, B. et al. Establishment of a proteomic profile associated with gonocyte and spermatogonial stem cell maturation and differentiation in neonatal mice. Proteomics 14, 274-85 (2014). 24339256 | 24339256 |
| 1678 | MYBL1 | ARP40093_P050 | The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 6, (2017). 29087293 | 29087293 |
| 1679 | MYBPH | ARP56598_P050 | Conti, A. et al. Increased expression of Myosin binding protein H in the skeletal muscle of amyotrophic lateral sclerosis patients. Biochim. Biophys. Acta 1842, 99-106 (2014). 24184715 | 24184715 |
| 1680 | MYCBP | ARP31860_P050 | Cowell, J. K. & Hawthorn, L. The application of microarray technology to the analysis of the cancer genome. Curr. Mol. Med. 7, 103-20 (2007). 17311536 | 17311536 |
| 1681 | MYCBP | ARP31860_P050 | Ramírez-Valle, F., Braunstein, S., Zavadil, J., Formenti, S. C. & Schneider, R. J. eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J. Cell Biol. 181, 293-307 (2008). 18426977 | 18426977 |
| 1682 | Myf5 | ARP32134_P050 | Yang, Z. et al. Mononuclear cells from dedifferentiation of mouse myotubes display remarkable regenerative capability. Stem Cells 32, 2492-501 (2014). 24916688 | 24916688 |
| 1683 | MYF5 | ARP41380_P050 | Deficient muscle regeneration potential in sarcopenic COPD patients: Role of satellite cells. J Cell Physiol 2021 4 236 3083-3098 32989805 | 32989805 |
| 1684 | MYH11 | OKEH05557 | Targeting ferroptosis protects against experimental (multi)organ dysfunction and death. Nat Commun 2022 1 13 1046 35210435 | 35210435 |
| 1685 | MYH7 | ARP41380_P050 | Tijore, A. et al. Investigating the Spatial Distribution of Integrin beta1 in Patterned Human Mesenchymal Stem Cells Using Super-Resolution Imaging. ACS Appl. Mater. Interfaces 6, 15686-96 (2014). 25153694 | 25153694 |
| 1686 | MYH7 | ARP41380_P050 | Role of Cytoskeletal Tension in the Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell. Adv Healthc Mater. 4, 1399-407 (2015). 25946615 | 25946615 |
| 1687 | Myh7 | ARP44434_P050 | High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy. Cell Death Dis 2021 2 12 216 33637715 | 33637715 |
| 1688 | MYH9 | ARP48072_P050 | Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation. Biol Open. 5, 452-60 (2016). 26977077 | 26977077 |
| 1689 | MYO1C | ARP56292_P050 | Identification of a 48 kDa form of unconventional myosin 1c in blood serum of patients with autoimmune diseases. Biochem Biophys Rep. 5, 175-179 (2016). 28955821 | 28955821 |
| 1690 | MYO1E | ARP56601_P050 | Crucial role for the LSP1-myosin1e bimolecular complex in the regulation of Fcγ receptor-driven phagocytosis. Mol Biol Cell. 26, 1652-64 (2015). 25717183 | 25717183 |
| 1691 | MYOG | OKEH03290 | Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS. Commun Biol. 4, 509 (2021) 33931719 | 33931719 |
| 1692 | N/A | OKEH02536 | Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells. Toxicol Lett 2017 NULL 272 94-100 28322891 | 28322891 |
| 1693 | N/A | OKEH02615 | Effect of Empagliflozin on Sphingolipid Catabolism in Diabetic and Hypertensive Rats. Int J Mol Sci 2022 5 23 NULL 35270028 | 35270028 |
| 1694 | N/A | OKEH02596 | Exploration of expanded carbohydrate chemical space to access biological activity using microwave-induced acid condensation of simple sugars. RSC Adv 2022 18 12 11075-11083 35425031 | 35425031 |
| 1695 | N/A | OKEH02594 | Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During Remission. Cell Mol Gastroenterol Hepatol 2021 4 12 1415-1432 34126236 | 34126236 |
| 1696 | N/A | OKEH02573 | Inhaled vitamin A is more effective than intramuscular dosing in mitigating hyperoxia-induced lung injury in a neonatal rat model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 2020 3 319 L576-L584 32755324 | 32755324 |
| 1697 | N/A | OKEH02561 | Sterculia tragacantha Lindl Leaf Extract Ameliorates STZ-Induced Diabetes, Oxidative Stress, Inflammation and Neuronal Impairment. J Inflamm Res 2021 NULL 14 6749-6764 34916823 | 34916823 |
| 1698 | N/A | OAAF05547 | Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA. Nat Commun 2022 1 13 1072 35228526 | 35228526 |
| 1699 | N/A | ARP44801_P050 | Comparison of methods for quantitative biomolecular interaction analysis. Anal Bioanal Chem 2022 1 414 661-673 34505164 | 34505164 |
| 1700 | N/A | AMM99021 | Epigenomic features of DNA G-quadruplexes and their roles in regulating rice gene transcription. Plant Physiol 2022 3 188 1632-1648 34893906 | 34893906 |
| 1701 | NAB1 | ARP32032_P050 | Shimoyamada, H. et al. Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. Am. J. Pathol. 177, 70-83 (2010). 20489156 | 20489156 |
| 1702 | NAMPT | ARP42255_T100 | Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight. Br. J. Pharmacol. (2017). 28055105 | 28055105 |
| 1703 | NANOG | ARP30891_P050 | Maimets, T., Neganova, I., Armstrong, L. & Lako, M. Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. Oncogene 27, 5277-87 (2008). 18521083 | 18521083 |
| 1704 | NANOG | ARP30891_P050 | Neganova, I., Zhang, X., Atkinson, S. & Lako, M. Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells. Oncogene 28, 20-30 (2009). 18806832 | 18806832 |
| 1705 | NANOG | ARP30891_P050 | Kallas, A., Pook, M., Maimets, M., Zimmermann, K. & Maimets, T. Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells. PLoS One 6, e19114 (2011). 21559451 | 21559451 |
| 1706 | NANOG | OAAB11202 | Identification and characterisation of NANOG+/ OCT-4high/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines. Oncotarget. 9, 7054-7065 (2018). 29467949 | 29467949 |
| 1707 | NANOG | P100591_P050 | Yang, C. et al. Opposing putative roles for canonical and noncanonical NFκB signaling on the survival, proliferation, and differentiation potential of human embryonic stem cells. Stem Cells 28, 1970-80 (2010). 20882529 | 20882529 |
| 1708 | NANOG | OAAB11202 | Doxorubicin resistant choriocarcinoma cell line derived spheroidal cells exhibit stem cell markers but reduced invasion.3 Biotech184129September2022 | 35875180 |
| 1709 | NAPE-PLD | ARP55927_P050 | Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related molecules in rat primary sensory neurons. J. Comp. Neurol. 525, 1778-1796 (2017). 27997038 | 27997038 |
| 1710 | NARS | OAAB07325 | Leucyl-tRNA synthetase is a tumour suppressor in breast cancer and regulates codon-dependent translation dynamics.Nat Cell Biol307-315243March2022 | 35288656 |
| 1711 | NAT2 | ARP44197_P050 | Population variability of rhesus macaque (Macaca mulatta) NAT1 gene for arylamine N-acetyltransferase 1: Functional effects and comparison with human. Sci Rep. 9, 10937 (2019). 31358821 | 31358821 |
| 1712 | ND6 | ARP50255_P050 | Karamanlidis, G. et al. Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ. Res. 106, 1541-8 (2010). 20339121 | 20339121 |
| 1713 | NDNF | ARP68872_P050 | Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism. Am J Hum Genet. 106, 58-70 (2020). 31883645 | 31883645 |
| 1714 | NDRG1 | OKEH02359 | Upregulation of NDRG1 predicts poor outcome and facilitates disease progression by influencing the EMT process in bladder cancer. Sci Rep. 9, 5166 (2019). 30914736 | 30914736 |
| 1715 | NDUFV3 | ARP45758_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 1716 | NEDD9 | OKEH02459 | Circulating NEDD9 is increased in pulmonary arterial hypertension: A multicenter, retrospective analysis. J Heart Lung Transplant. 39, 289-299 (2020). 31952977 | 31952977 |
| 1717 | NEFL | OKCD01380 | Neurofilament Light Chain Is a Novel Biomarker for Major Depression and Related Executive Dysfunction.Int J Neuropsychopharmacol99-105252February2022 | 34637515 |
| 1718 | NELL2 | OKCD01073 | NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth. Cell Rep. 36, 109254 (2021) 34233189 | 34233189 |
| 1719 | NEU1 | ARP44286_T100 | Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll-like Receptor 4. J Neurochem. 155, 403-416 (2020) 32279315 | 32279315 |
| 1720 | NEU1 | ARP44286_T100 | Existence of NEU1 sialidase on mouse thymocytes whose natural substrate is CD5. Glycobiology. 28, 306-317 (2018) 29897583 | 29897583 |
| 1721 | NEUROD1 | ARP32036_T100 | Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors. PLoS One. 7, e37952 (2012). 22666422 | 22666422 |
| 1722 | NFATC2 | ARP37106_T100 | Heer, R. et al. Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3. Urology 76, 509.e13-20 (2010). 20546875 | 20546875 |
| 1723 | NFATC2 | ARP37106_T100 | Nagamoto-Combs, K. & Combs, C. K. Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells). J. Neurosci. 30, 9641-6 (2010). 20631193 | 20631193 |
| 1724 | NFE2L2 | OAED00103 | Potential for transcriptional upregulation of cochlin in glaucomatous trabecular meshwork: a combinatorial bioinformatic and biochemical analytical approach. Invest Ophthalmol Vis Sci. 50, 3106-11 (2009) 19098315 | 19098315 |
| 1725 | NFE2L2 | OKCD02754 | Intermittent Hypoxia and Its Impact on Nrf2/HIF-1α Expression and ABC Transporters: An in Vitro Human Blood-Brain Barrier Model Study. Cell Physiol Biochem. 54, 1231-1248 (2020). 33326735 | 33326735 |
| 1726 | NFE2L2 | OKEH03531 | Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing. JBMR Plus. 5, e10425 (2021). 33869985 | 33869985 |
| 1727 | NFIA | ARP32714_P050 | PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep. 5, 10668 (2015). 26021864 | 26021864 |
| 1728 | NFIA | ARP39574_P050 | DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife 2021 NULL 10 NULL 33871356 | 33871356 |
| 1729 | NFIC | P100819_T100 | Liang, B., Tikhanovich, I., Nasheuer, H. P. & Folk, W. R. Stimulation of BK virus DNA replication by NFI family transcription factors. J. Virol. 86, 3264-75 (2012). 22205750 | 22205750 |
| 1730 | NFKB1 | OAAI00072 | Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 17, 4213-4220 (2018). 29344664 | 29344664 |
| 1731 | NFKB1 | OKCD07698 | Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression. Aging Dis 2022 2 13 583-613 35371600 | 35371600 |
| 1732 | NFKB2 | ARP32718_P050 | Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. Virology. 494, 1-14 (2016). 27061052 | 27061052 |
| 1733 | NFS1 | ARP33115_T100 | A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis. J Biol Chem. 283, 9231-8 (2008). 18270200 | 18270200 |
| 1734 | NF-κB2 | ARP32043_P050 | Volger, O. L. et al. Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am. J. Pathol. 171, 326-37 (2007). 17591977 | 17591977 |
| 1735 | NF-κB2 | ARP32043_P050 | Wang, C.-Y., Yang, P., Li, M. & Gong, F. Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity. Biochem. Biophys. Res. Commun. 381, 477-81 (2009). 19222990 | 19222990 |
| 1736 | NGF | OKEH00186 | Dysfunctional neuroplasticity in newly arrived Middle Eastern refugees in the U.S.: Association with environmental exposures and mental health symptoms. PLoS One. 15, e0230030 (2020). 32142533 | 32142533 |
| 1737 | NIP7 | ARP40833_T100 | Zinzalla, V., Stracka, D., Oppliger, W. & Hall, M. N. Activation of mTORC2 by association with the ribosome. Cell 144, 757-68 (2011). 21376236 | 21376236 |
| 1738 | NKCC2 | ARP41388_P050 | Kelsen, S. et al. Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells. Am. J. Physiol. Renal Physiol. 295, F1158-65 (2008). 18701634 | 18701634 |
| 1739 | NKCC2 | ARP41388_P050 | Stec, D. E. et al. Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension. J. Am. Soc. Nephrol. 23, 834-41 (2012). 22323644 | 22323644 |
| 1740 | NKCC2 | ARP41388_P050 | Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice. Am. J. Physiol. Renal Physiol. 311, F752-F762 (2016). 27440775 | 27440775 |
| 1741 | Nkx1-2 | ARP36974_P050 | Buniello, A. et al. Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One 8, e56274 (2013). 23457544 | 23457544 |
| 1742 | NKX3-2 | ARP58064_P050 | Kamel, G. et al. Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Dev. Biol. 381, 423-33 (2013). 23806211 | 23806211 |
| 1743 | NLRC4 | AVARP00019_P050 | Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation. Am J Physiol Renal Physiol. 306, F299-308 (2014). 24285499 | 24285499 |
| 1744 | NLRC4 | AVARP00019_P050 | The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells). Int Urol Nephrol. 47, 1953-64 (2015). 26490556 | 26490556 |
| 1745 | NLRC4 | ARP38041_P050 | Immunohistochemical Study of ASC Expression and Distribution in the Hippocampus of an Aged Murine Model of Alzheimer's Disease. Int J Mol Sci 2021 16 22 NULL 34445402 | 34445402 |
| 1746 | NLRP12 | OAAB04256 | NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. Elife. 8, (2019). 30990169 | 30990169 |
| 1747 | NLRP3 | OKCD04232 | Targeting Oxidative Stress, NLRP3 Inflammasome, and Autophagy by Fraxetin to Combat Doxorubicin-Induced Cardiotoxicity. Pharmaceuticals (Basel). 14 (2021). 34832970 | 34832970 |
| 1748 | NLRP3 | OKEH03368 | Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models. J Pers Med. 10, NULL (2020). 33086484 | 33086484 |
| 1749 | NLRP3 | OKEH03368 | NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells. Int J Mol Sci. 21, NULL (2020). 33096896 | 33096896 |
| 1750 | NLRP3 | OKEH03368 | Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome Expression. Front Oncol. 11, 680758 (2021). 34178667 | 34178667 |
| 1751 | NLRP3 | OKEH05486 | Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models. J Pers Med. 10, NULL (2020). 33086484 | 33086484 |
| 1752 | NLRP3 | OKEH03368 | Serum Copeptin, NLPR3, and suPAR Levels among Patients with Autosomal-Dominant Polycystic Kidney Disease with and without Impaired Renal Function. Cardiorenal Med 2020 6 10 440-451 33202410 | 33202410 |
| 1753 | NLRP3 | OKCD09236 | Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression. Aging Dis 2022 2 13 583-613 35371600 | 35371600 |
| 1754 | NLRP3 | OKCD04232 | Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats. Antioxidants (Basel) 2022 3 11 NULL 35326164 | 35326164 |
| 1755 | NLRP3 | ARP49065_P050 | Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora. Front Pharmacol 2022 NULL 13 805266 35431939 | 35431939 |
| 1756 | NLRP3 | OKEH03368 | NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis C.Mediators Inflamm69179192021NULLNovember2021 | 34840527 |
| 1757 | NLRP3 | OKEH05486 | Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways.Front Cardiovasc Med9307979NULLSeptember2022 | 36158826 |
| 1758 | NME1 | OKEH02350 | Zhenhua Du, et al. Quantitative proteomics identifies a plasma multi-protein model for detection of hepatocellular carcinoma. 15552 (2020). 32968147 | 32968147 |
| 1759 | NMT1 | OKEH02201 | Epigenetics, N-myrystoyltransferase-1 and casein kinase-2-alpha modulates the increased replication of HIV-1 CRF02_AG, compared to subtype-B viruses. Sci Rep. 9, 10689 (2019). 31337802 | 31337802 |
| 1760 | NNMT | ARP42281_T100 | Ulanovskaya, O. A., Zuhl, A. M. & Cravatt, B. F. NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. Nat. Chem. Biol. 9, 300-6 (2013). 23455543 | 23455543 |
| 1761 | NNMT | ARP42281_T100 | Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nat Med. 21, 887-94 (2015). 26168293 | 26168293 |
| 1762 | NNMT | ARP42281_T100 | Genetic Nicotinamide N-Methyltransferase (Nnmt) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance. Diabetes. 68, 527-542 (2019). 30552109 | 30552109 |
| 1763 | NONO | ARP40715_T100 | Bubenik, J. L., Ladd, A. N., Gerber, C. A., Budiman, M. E. & Driscoll, D. M. Known turnover and translation regulatory RNA-binding proteins interact with the 3’ UTR of SECIS-binding protein 2. RNA Biol. 6, 73-83 (2009). 19106619 | 19106619 |
| 1764 | Noradrenaline | OKEH02565 | A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53. Cell Rep. 30, 783-792.e5 (2020). 31968253 | 31968253 |
| 1765 | Noradrenaline | OKEH02565 | The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model. Int J Mol Sci. 21, (2020). 33371319 | 33371319 |
| 1766 | NORMAL HEPARINISED CANINE PLASMA | OOMA00031 | Identification of recombinant human EPO variants in greyhound plasma and urine by ELISA, LC-MS/MS and western blotting: a comparative study. Drug Test Anal. 8, 164-76 (2016). 26290355 | 26290355 |
| 1767 | NOTCH2 | ARP32723_P050 | Tilley, A. E. et al. Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 179, 457-66 (2009). 19106307 | 19106307 |
| 1768 | NOTCH4 | ARP32726_P050 | Sun, Y. et al. Trp53 regulates Notch 4 signaling through Mdm2. J. Cell Sci. 124, 1067-76 (2011). 21402876 | 21402876 |
| 1769 | NOTCH4 | ARP32726_P050 | Notch-Induced Expression of FZD7 Requires Noncanonical NOTCH3 Signaling in Human Breast Epithelial Cells. Stem Cells Dev. 25, 522-9 (2016). 26847503 | 26847503 |
| 1770 | NOTCH4 | OASG05123 | Notch1 signaling determines the plasticity and function of fibroblasts in diabetic wounds. Life Sci Alliance. 3, NULL (2020). 33109684 | 33109684 |
| 1771 | NOX1 | ARP46818_P050 | Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase. Metab Brain Dis. 32, 41-49 (2017). 27476541 | 27476541 |
| 1772 | NOX5 | OAEB01075 | Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation. Front Physiol. 8, 994 (2018). 29375391 | 29375391 |
| 1773 | NPAS4 | ARP32556_P050 | Pruunsild, P., Sepp, M., Orav, E., Koppel, I. & Timmusk, T. Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J. Neurosci. 31, 3295-308 (2011). 21368041 | 21368041 |
| 1774 | NPC2 | OKCD01269 | Hiroaki Yagi, et al. Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression. 6429 (2020). 32286426 | 32286426 |
| 1775 | NPHS2 | OKEH00672 | The Presence of Urinary Renal Progenitor Cells in Stable Kidney Transplant Recipients Anticipates Allograft Deterioration. Front Physiol. 9, 1412 (2018). 30364198 | 30364198 |
| 1776 | NPM1 | ARP34094_T100 | Komorek, J. et al. Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J. Virol. 84, 2719-31 (2010). 20053746 | 20053746 |
| 1777 | NPPC | OKEH03207 | Chizuru Sogawa-Fujiwara, et al. Defective development and microcirculation of intestine in Npr2 mutant mice. 14761 (2020). 32901096 | 32901096 |
| 1778 | NPTX1 | OKDD00433 | Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease. Neurobiol Dis 2018 NULL 114 120-128 29501530 | 29501530 |
| 1779 | NQO1 | OKCD02727 | Radiomodulatory effect of a non-electrophilic NQO1 inducer identified in a screen of new 6, 8-diiodoquinazolin-4(3H)-ones carrying a sulfonamide moiety. Eur J Med Chem. 200, 112467 (2020). 32502866 | 32502866 |
| 1780 | NR1H2 | ARP38906_T100 | Bogan, R. L. & Hennebold, J. D. The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteum. Reproduction 139, 163-76 (2010). 19776099 | 19776099 |
| 1781 | NR1I2 | ARP36016_P050 | Sivertsson, L., Edebert, I., Palmertz, M. P., Ingelman-Sundberg, M. & Neve, E. P. A. Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation. Mol. Pharmacol. 83, 659-70 (2013). 23264496 | 23264496 |
| 1782 | NR1I2 | ARP36016_P050 | Dou, W. et al. Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway. J. Pharmacol. Exp. Ther. 345, 473-82 (2013). 23536316 | 23536316 |
| 1783 | NR2E3 | ARP39069_T100 | Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer. EMBO Mol Med. 4, 52-67 (2012). 22174013 | 22174013 |
| 1784 | NR2E3 | ARP39069_T100 | Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Sci Rep. 7, 10662 (2017). 28878246 | 28878246 |
| 1785 | NR2E3 | ARP39070_P050 | Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Sci Rep. 7, 10662 (2017). 28878246 | 28878246 |
| 1786 | NR2E3 | OAAB10504 | Differential dimerization of variants linked to enhanced S-cone sensitivity syndrome (ESCS) located in the NR2E3 ligand-binding domain. Hum Mutat. 36, 599-610 (2015). 25703721 | 25703721 |
| 1787 | NR2F2 | P100816_P050 | Déjardin, J. & Kingston, R. E. Purification of proteins associated with specific genomic Loci. Cell 136, 175-86 (2009). 19135898 | 19135898 |
| 1788 | NR4A1 | ARP31941_T100 | Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation. Mol Cell. 69, 480-492.e7 (2018). 29395065 | 29395065 |
| 1789 | NR4A1 | ARP45604_P050 | Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development. Neuron. 91, 1219-27 (2016). 27657449 | 27657449 |
| 1790 | NR4A2 | ARP38753_P050 | Epigenetic Reprogramming of Cortical Neurons through Alteration of Dopaminergic Circuits. Mol Psychiatry. 19, 1193-1200 (2014). 25023144 | 25023144 |
| 1791 | NRF1 | ARP34523_P050 | Teodoro, J. S. et al. Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation. Mitochondrion 13, 637-46 (2013). 24041461 | 24041461 |
| 1792 | NRG1 | OKEH02851 | Targeting Neuregulin 1 (NRG1): A Novel Biomarker for Non-Small-Cell Lung Cancer. J Environ Pathol Toxicol Oncol. 40, 61-72 (2021). 34936301 | 34936301 |
| 1793 | NSMF | OAAN03468 | NSMF promotes the replication stress-induced DNA damage response for genome maintenance. Nucleic Acids Res. 49, 5605-5622 (2021) 33963872 | 33963872 |
| 1794 | NSUN2 | ARP48811_P050 | Stem cell function and stress response are controlled by protein synthesis. Nature. 534, 335-40 (2016). 27306184 | 27306184 |
| 1795 | NT5C3 | ARP65373_P050 | Preanalytical Stability of Gemcitabine and its Metabolite 2', 2'-Difluoro-2'-Deoxyuridine in Whole Blood-Assessed by Liquid Chromatography Tandem Mass Spectrometry. J Pharm Sci 2015 12 104 4427-4432 26372902 | 26372902 |
| 1796 | NT5C3A | ARP32185_P050 | The intracellular pyrimidine 5'-nucleotidase NT5C3A is a negative epigenetic factor in interferon and cytokine signaling. Sci Signal. 11, (2018). 29463777 | 29463777 |
| 1797 | NT-proBNP | OKCA00041 | Analysis of NT-proBNP and uric acid due to left ventricle hypertrophy in the patients of aortic valve disease. Pak J Med Sci. 35, 183-188 (2019). 30881420 | 30881420 |
| 1798 | NT-PROBNP | OKEH00475 | Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF‑κB signalling pathway in diabetic cardiomyopathy rats. Mol Med Rep. 23, 1 (2021). 33495841 | 33495841 |
| 1799 | NUCB1 | P101699_T100 | Lin, P. et al. Calnuc binds to Alzheimer’s beta-amyloid precursor protein and affects its biogenesis. J. Neurochem. 100, 1505-14 (2007). 17348862 | 17348862 |
| 1800 | NUCB1 | P102230_P050 | Valencia, C. A., Cotten, S. W., Duan, J. & Liu, R. Modulation of nucleobindin-1 and nucleobindin-2 by caspases. FEBS Lett. 582, 286-90 (2008). 18154733 | 18154733 |
| 1801 | NUCB1 | P102230_P050 | Sugeno, N. et al. Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death. J. Biol. Chem. 283, 23179-88 (2008). 18562315 | 18562315 |
| 1802 | NUCB1 | P102230_P050 | Lin, P., Fischer, T., Lavoie, C., Huang, H. & Farquhar, M. G. Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells. Mol. Neurodegener. 4, 15 (2009). 19320978 | 19320978 |
| 1803 | NUCB1 | P102230_P050 | Larkin, H., Ribeiro, M. G. & Lavoie, C. Topology and Membrane Anchoring of the Lysosomal Storage Disease-Related Protein CLN5. Hum. Mutat. 34, 1688-97 (2013). 24038957 | 24038957 |
| 1804 | NUCB1 | P102230_P050 | Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization. Sci Rep. 7, 42880 (2017). 28220836 | 28220836 |
| 1805 | NUCB1 | P102230_T100 | Calnuc Function in Endosomal Sorting of Lysosomal Receptors. Traffic. 17, 416-32 (2016). 26756199 | 26756199 |
| 1806 | NUCB2 | ARP36567_T100 | Suzuki, S. et al. Nucleobindin 2 in human breast carcinoma as a potent prognostic factor. Cancer Sci. 103, 136-43 (2012). 21988594 | 21988594 |
| 1807 | NUCB2 | ARP36567_T100 | Nucleobindin 2 (NUCB2) in human endometrial carcinoma: a potent prognostic factor associated with cell proliferation and migration. Endocr. J. 63, 287-99 (2016). 26842712 | 26842712 |
| 1808 | Nucleophosmin | ARP34094_T100 | Lin, S., Coutinho-Mansfield, G., Wang, D., Pandit, S. & Fu, X.-D. The splicing factor SC35 has an active role in transcriptional elongation. Nat. Struct. Mol. Biol. 15, 819-26 (2008). 18641664 | 18641664 |
| 1809 | NUR77 | ARP31941_T100 | Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nat Commun. 8, 14420 (2017). 28240261 | 28240261 |
| 1810 | NUTF2 | ARP64840_P050 | Nuclear Transport Factor 2 (NTF2) suppresses WM983B metastatic melanoma by modifying cell migration, metastasis, and gene expression. Sci Rep. 11, 23586 (2021). 34880267 | 34880267 |
| 1811 | OAS1 | ARP30587_P050 | Li, Q. & Tainsky, M. A. Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway. Cancer Res. 71, 255-65 (2011). 21199806 | 21199806 |
| 1812 | OAS1 | ARP51359_P050 | Zhu, W. et al. RIG-I-like receptors mediate innate antiviral response in mouse testis. Mol. Endocrinol. 27, 1455-67 (2013). 23820901 | 23820901 |
| 1813 | OAS1 | ARP51359_P050 | Yu, L. et al. Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells. Immunol. Cell Biol. 92, 105-15 (2014). 24165978 | 24165978 |
| 1814 | OAS1G | ARP40402_P050 | Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis. Immunity. 52, 542-556.e13 (2020) 32187520 | 32187520 |
| 1815 | OCLN | ARP42889_P050 | Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier. Oncotarget. 7, 63839-63855 (2016). 27588479 | 27588479 |
| 1816 | OCT1 | ARP37619_T100 | Gupta, S. et al. Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. J. Pharmacol. Exp. Ther. 341, 16-23 (2012). 22202118 | 22202118 |
| 1817 | OCT6 | ARP33061_T100 | Hashimoto, Y. et al. Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer. Breast Cancer Res. Treat. 145, 101-11 (2014). 24671357 | 24671357 |
| 1818 | OCT6 | ARP44073_T100 | Immunohistochemical expression profiles of solute carrier transporters in alpha-fetoprotein-producing gastric cancer. Histopathology. 69, 812-821 (2016). 27245475 | 27245475 |
| 1819 | ODF1 | ARP53765_P050 | Vilagran, I. et al. Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars. Theriogenology 82, 418-26 (2014). 24933094 | 24933094 |
| 1820 | ODF1 | ARP53765_P050 | Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality. Anim. Reprod. Sci. 165, 22-30 (2016). 26711247 | 26711247 |
| 1821 | OGT | ARP49154_P050-FITC | Robust effect of metabolic syndrome on major metabolic pathways in the myocardium. PLoS One. 14, e0225857 (2019). 31790488 | 31790488 |
| 1822 | OMA1 | ARP52818_P050 | Bohovych, I., Donaldson, G., Christianson, S., Zahayko, N. & Khalimonchuk, O. Stress-triggered activation of the metalloprotease Oma1 involves its C-terminal region and is important for mitochondrial stress protection in yeast. J. Biol. Chem. 289, 13259-72 (2014). 24648523 | 24648523 |
| 1823 | OMA1 | ARP52818_P050 | Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability. Sci Rep. 5, 13989 (2015). 26365306 | 26365306 |
| 1824 | OMA1 | ARP52818_P050 | Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells. Sci Rep. 9, 14746 (2019). 31611601 | 31611601 |
| 1825 | OMD | OKEH03353 | Enhanced epigenetic profiling of classical human monocytes reveals a specific signature of healthy aging in the DNA methylome. Nat Aging 2021 1 1 124-141 34796338 | 34796338 |
| 1826 | OMD | OKEH03353 | Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification.Clin Transl Mede682122February2022 | 35184400 |
| 1827 | ONECUT1 | ARP38481_P050 | Yuan, X.-W. et al. Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition. J. Biol. Chem. 288, 31206-16 (2013). 24022481 | 24022481 |
| 1828 | OPA1 | ARP57715_P050 | Iron-induced energy supply deficiency and mitochondrial fragmentation in neurons. J Neurochem. 147, 816-830 (2018) 30380148 | 30380148 |
| 1829 | OPN1MW | ARP59764_P050 | Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish. Hum Mol Genet. 24, 4648-59 (2015). 26034134 | 26034134 |
| 1830 | OPN1SW | ARP48137_T100 | In vivo analysis of onset and progression of retinal degeneration in the Nr2e3rd7/rd7 mouse model of enhanced S-cone sensitivity syndrome. Sci Rep 2021 1 11 19032 34561487 | 34561487 |
| 1831 | OPN5 | ARP59824_P050 | Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles. Proc. Natl. Acad. Sci. U.S.A. 113, 6053-8 (2016). 27166423 | 27166423 |
| 1832 | OR14I1 | ARP71293_P050 | OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism. Proc Natl Acad Sci U S A. 116, 7043-7052 (2019). 30894498 | 30894498 |
| 1833 | ORP150 | ARP46716_P050 | Expression and function of HSP110 family in mouse testis after vasectomy. Asian J. Androl. (2016). 26952955 | 26952955 |
| 1834 | OTC | ARP41766_T100 | Yu, W. et al. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. J. Biol. Chem. 284, 13669-75 (2009). 19318352 | 19318352 |
| 1835 | OTC | ARP41766_T100 | Walters, M. W. & Wallace, K. B. Urea cycle gene expression is suppressed by PFOA treatment in rats. Toxicol. Lett. 197, 46-50 (2010). 20452409 | 20452409 |
| 1836 | OTC | ARP41766_T100 | Hallows, W. C. et al. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol. Cell 41, 139-49 (2011). 21255725 | 21255725 |
| 1837 | OTX2 | ARP32439_P050 | Aluigi, M. G., Angelini, C., Corte, G. & Falugi, C. The sea urchin, Paracentrotus lividus, embryo as a “bioethical” model for neurodevelopmental toxicity testing: effects of diazinon on the intracellular distribution of OTX2-like proteins. Cell Biol. Toxicol. 24, 587-601 (2008). 18224450 | 18224450 |
| 1838 | OTX2 | ARP32439_P050 | Machalińska, A. et al. Endogenous regeneration of damaged retinal pigment epithelium following low dose sodium iodate administration: an insight into the role of glial cells in retinal repair. Exp. Eye Res. 112, 68-78 (2013). 23623997 | 23623997 |
| 1839 | OVAL | OKCD01353 | Lung megakaryocytes are immune modulatory cells. J Clin Invest. 131, NULL (2021). 33079726 | 33079726 |
| 1840 | OVOL1 | ARP38500_T100 | OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc. Natl. Acad. Sci. U.S.A. 112, E6175-84 (2015). 26504231 | 26504231 |
| 1841 | P2RX5 | ARP35511_P050 | The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts. Sci Rep. 7, 196 (2017). 28298636 | 28298636 |
| 1842 | P2RX7 | OASA05733 | Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responses. Am J Transplant. 14, 1512-22 (2014). 24866539 | 24866539 |
| 1843 | P2RY1 | ARP51293_P050 | Dilip, R. et al. Distribution and development of P2Y1-purinoceptors in the mouse retina. J. Mol. Histol. 44, 639-44 (2013). 23907621 | 23907621 |
| 1844 | P2X7 | ARP35518_T100 | Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Mol. Cancer. 14, 201 (2015). 26597723 | 26597723 |
| 1845 | P53 | OAAI00285 | Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis.Fundam Clin Pharmacol968-978356December2021 | 33609317 |
| 1846 | PA | OAAF04963 | Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method.Biomed ChromatogrNULL323March2018 | 29088495 |
| 1847 | PABPC1 | OAAB01699 | Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation. PLoS One. 12, e0172420 (2017). 28212427 | 28212427 |
| 1848 | PABPC4 | ARP40495_P050 | Liu, D. et al. Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis. J. Genet. Genomics 39, 369-74 (2012). 22884093 | 22884093 |
| 1849 | PALM | ARP56270_P050 | Konzer, A. et al. Stable isotope labeling in zebrafish allows in vivo monitoring of cardiac morphogenesis. Mol. Cell. Proteomics 12, 1502-12 (2013). 23412571 | 23412571 |
| 1850 | PALMD | ARP66420_P050 | Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One. 8, e58456 (2013). 23520512 | 23520512 |
| 1851 | PANX1 | ARP42783_P050 | Dietary Fatty Acids Affect Red Blood Cell Membrane Composition and Red Blood Cell ATP Release in Dairy Cows. Int J Mol Sci. 20, (2019). 31195708 | 31195708 |
| 1852 | Panx2 | ARP42778_T100 | Wang, X.-H., Streeter, M., Liu, Y.-P. & Zhao, H.-B. Identification and characterization of pannexin expression in the mammalian cochlea. J. Comp. Neurol. 512, 336-46 (2009). 19009624 | 19009624 |
| 1853 | Panx2 | ARP42778_T100 | Lai, C. P. K., Bechberger, J. F. & Naus, C. C. Pannexin2 as a novel growth regulator in C6 glioma cells. Oncogene 28, 4402-8 (2009). 19749789 | 19749789 |
| 1854 | Panx2 | ARP42778_T100 | Mylvaganam, S. et al. Hippocampal seizures alter the expression of the pannexin and connexin transcriptome. J. Neurochem. 112, 92-102 (2010). 19840216 | 19840216 |
| 1855 | Panx2 | ARP42778_T100 | Swayne, L. A., Sorbara, C. D. & Bennett, S. A. L. Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. J. Biol. Chem. 285, 24977-86 (2010). 20529862 | 20529862 |
| 1856 | Panx2 | ARP42778_T100 | Wicki-Stordeur, L. E., Boyce, A. K. J. & Swayne, L. A. Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization. Cell Commun. Adhes. 20, 73-9 (2013). 23659289 | 23659289 |
| 1857 | PANX2 | ARP42778_T100 | Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells. Invest Ophthalmol Vis Sci. 58, 5654-5665 (2017). 29098296 | 29098296 |
| 1858 | PANX2 | ARP42778_T100 | Human stem cells express pannexins. BMC Res Notes. 11, 54 (2018). 29357945 | 29357945 |
| 1859 | PANX2 | ARP42778_T100 | Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes. Mol Biol Cell. mbcE21080387 (2022). 34985913 | 34985913 |
| 1860 | PAQR6 | ARP49900_P050 | Progestin-mediated activation of MAPK and AKT in nuclear progesterone receptor negative breast epithelial cells: The role of membrane progesterone receptors. Gene. 591, 6-13 (2016). 27349565 | 27349565 |
| 1861 | PAR2 | ARP60034_P050 | Yau, M.-K., Liu, L. & Fairlie, D. P. Toward drugs for protease-activated receptor 2 (PAR2). J. Med. Chem. 56, 7477-97 (2013). 23895492 | 23895492 |
| 1862 | PARD6A | ARP42883_P050 | Faulty oxygen sensing disrupts angiomotin function in trophoblast cell migration and predisposes to preeclampsia. JCI Insight. 4, (2019). 30996134 | 30996134 |
| 1863 | PARL | ARP44851_P050 | Yoshioka, H. et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J. Cereb. Blood Flow Metab. 33, 1658-65 (2013). 23921894 | 23921894 |
| 1864 | PARL | ARP44851_P050 | Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease. Mol Neurodegener. 16, 15 (2021) 33685483 | 33685483 |
| 1865 | PARP10 | ARP42810_P050 | DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. Mol Cancer. 13, 125 (2014). 24886089 | 24886089 |
| 1866 | PARP12 | OAAB03451 | DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. Mol Cancer. 13, 125 (2014). 24886089 | 24886089 |
| 1867 | PARP16 | ARP33752_P050 | Di Paola, S., Micaroni, M., Di Tullio, G., Buccione, R. & Di Girolamo, M. PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-s1. PLoS One 7, e37352 (2012). 22701565 | 22701565 |
| 1868 | PARP16 | ARP53281_P050 | SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation. Acta Pharm Sin B 2021 5 11 1261-1273 34094832 | 34094832 |
| 1869 | PAX2 | ARP31220_P050 | Yu, A. L. et al. Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes. Exp. Eye Res. 84, 694-706 (2007). 17261280 | 17261280 |
| 1870 | PAX2 | ARP31220_P050 | Yu, A. L. et al. Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression. Invest. Ophthalmol. Vis. Sci. 50, 1707-17 (2009). 18952926 | 18952926 |
| 1871 | PAX2 | ARP31220_P050 | Hurtado, A. et al. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 456, 663-6 (2008). 19005469 | 19005469 |
| 1872 | PAX2 | ARP31220_P050 | Lee, S. B. et al. PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells. PLoS One 6, e22312 (2011). 21876729 | 21876729 |
| 1873 | PAX2 | ARP31220_P050 | Viringipurampeer, I. A. et al. Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. Hum. Mol. Genet. 21, 2357-69 (2012). 22357656 | 22357656 |
| 1874 | PAX2 | ARP31220_P050 | Palmieri, C. et al. Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance. Br. J. Cancer 108, 2039-44 (2013). 23652306 | 23652306 |
| 1875 | PAX4 | ARP32064_P050 | Zhang, L. et al. KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers. Am. J. Surg. Pathol. 33, 1562-9 (2009). 19574886 | 19574886 |
| 1876 | PAX7 | AAP32742 | Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy. Hum. Mol. Genet. 25, 2465-2482 (2016). 27154199 | 27154199 |
| 1877 | Pax7 | ARP30947_P050 | Ezin, A. M., Sechrist, J. W., Zah, A., Bronner, M. & Fraser, S. E. Early regulative ability of the neuroepithelium to form cardiac neural crest. Dev. Biol. 349, 238-49 (2011). 21047505 | 21047505 |
| 1878 | Pax7 | ARP30947_P050 | Van Ry, P. M., Minogue, P., Hodges, B. L. & Burkin, D. J. Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy. Hum. Mol. Genet. (2013). doi:10.1093/hmg/ddt428 24009313 | 24009313 |
| 1879 | PAX7 | ARP30947_P050 | mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation. Skelet Muscle. 11, 18 (2021). 34238354 | 34238354 |
| 1880 | PAX7 | ARP32742_P050 | Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development. 138, 3647-56 (2011). 21828093 | 21828093 |
| 1881 | PAX7 | ARP32742_P050 | Cell-autonomous Notch activity maintains the temporal specification potential of skeletal muscle stem cells. Development. 139, 4536-48 (2012). 23136394 | 23136394 |
| 1882 | PAX7 | ARP32742_P050 | Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4. Dev Biol. 381, 241-55 (2013). 23623977 | 23623977 |
| 1883 | Pax7 | ARP32742_P050 | McDonald, A. A., Kunz, M. D. & McLoon, L. K. Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice. PLoS One 9, e86424 (2014). 24466085 | 24466085 |
| 1884 | PAX7 | ARP32742_P050 | First Neuromuscular Contact Correlates with Onset of Primary Myogenesis in Rat and Mouse Limb Muscles. PLoS One. 10, e0133811 (2015). 26207754 | 26207754 |
| 1885 | PAX7 | ARP32742_P050 | CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury. Nat Commun. 6, 7792 (2015). 26242746 | 26242746 |
| 1886 | PAX7 | ARP32742_P050 | Early myogenic responses to acute exercise before and after resistance training in young men. Physiol Rep. 3, (2015). 26359239 | 26359239 |
| 1887 | PAX7 | ARP32742_P050 | Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis. Neuromuscul. Disord. 25, 873-87 (2015). 26429098 | 26429098 |
| 1888 | PAX7 | ARP32742_P050 | Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy. Hum. Mol. Genet. 25, 2465-2482 (2016). 27154199 | 27154199 |
| 1889 | PAX7 | ARP32742_P050 | Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7. Cell Cycle. 15, 2931-2942 (2016). 27610933 | 27610933 |
| 1890 | PAX7 | ARP32742_P050 | Laminin differentially regulates the stemness of type I and type II pericytes. Stem Cell Res Ther. 8, 28 (2017). 28173861 | 28173861 |
| 1891 | PAX7 | ARP32742_P050 | A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. J Biol Chem. 293, 13509-13523 (2018). 29991592 | 29991592 |
| 1892 | PAX7 | ARP32742_P050 | The transcription factor Lef1 switches partners from β-catenin to Smad3 during muscle stem cell quiescence. Sci Signal. 11, NULL (2018). 30042129 | 30042129 |
| 1893 | PAX7 | ARP32742_P050 | The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38a MAP kinase and redox regulation of muscle regeneration. Elife. 7, (2018). 30106373 | 30106373 |
| 1894 | PAX7 | ARP32742_P050 | PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress. Cell Stem Cell. 24, 958-973.e9 (2019). 31006622 | 31006622 |
| 1895 | PAX7 | ARP32742_P050 | The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol. 21, 25 (2020). 32293249 | 32293249 |
| 1896 | PBRM1 | ARP39332_P050 | smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish. Sci Rep. 8, 15369 (2018). 30337622 | 30337622 |
| 1897 | PCBP2 | ARP40568_T100 | Han, W. et al. RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3. J. Clin. Invest. 123, 2103-18 (2013). 23585479 | 23585479 |
| 1898 | PCBP2 | ARP40568_T100 | Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion. Oncotarget. 7, 19483-98 (2016). 26761212 | 26761212 |
| 1899 | PCK1 | ARP32801_P050 | Perrone, C. E. et al. Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle. J. Nutrigenet. Nutrigenomics 5, 132-57 (2012). 23052097 | 23052097 |
| 1900 | PCNA | AVARP03018_T100 | Liu, Z. et al. Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure. Cytotherapy 16, 1207-19 (2014). 25108650 | 25108650 |
| 1901 | PCT | OKEH02858 | Shen-Ling-Bai-Zhu-San Enhances the Antipneumonia Effect of Cefixime in Children by Ameliorating Gut Microflora, Inflammation, and Immune Response.Evid Based Complement Alternat Med77524262022NULLSeptember2022 | 36118084 |
| 1902 | PDCD4 | AVARP09045_P050 | Pan, Q., Luo, X. & Chegini, N. microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells. Mol. Hum. Reprod. 16, 215-27 (2010). 19906824 | 19906824 |
| 1903 | PDCD4 | AVARP09045_P050 | Folini, M. et al. miR-21: an oncomir on strike in prostate cancer. Mol. Cancer 9, 12 (2010). 20092645 | 20092645 |
| 1904 | PDE4D | OAGA00330 | Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation. Elife. 5, (2016). 27383270 | 27383270 |
| 1905 | PDE5A | ARP63250_P050 | A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium. Theriogenology. 85, 428-33 (2016). 26443234 | 26443234 |
| 1906 | PDHA1 | ARP37713_T100 | The tumor suppressor gene lkb1 is essential for glucose homeostasis during zebrafish early development. FEBS Lett 2016 14 590 2076-85 27264935 | 27264935 |
| 1907 | PDSS1 | ARP46195_T100 | Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum. J Neuropathol Exp Neurol. 75, 663-72 (2016). 27235405 | 27235405 |
| 1908 | PDXP | OKEH01229 | PLPP/CIN-mediated NEDD4-2 S448 dephosphorylation regulates neuronal excitability via GluA1 ubiquitination. Cell Death Dis. 10, 545 (2019). 31320629 | 31320629 |
| 1909 | PDXP | OKEH03398 | PLPP/CIN-mediated NEDD4-2 S448 dephosphorylation regulates neuronal excitability via GluA1 ubiquitination. Cell Death Dis. 10, 545 (2019). 31320629 | 31320629 |
| 1910 | PENK | OAEB00439 | Stress-Related Neuronal Clusters in Sublenticular Extended Amygdala of Basal Forebrain Show Individual Differences of Positions. Front Neural Circuits. 14, 29 (2020). 32547372 | 32547372 |
| 1911 | PEO1 | ARP36483_P050 | Ylikallio, E., Tyynismaa, H., Tsutsui, H., Ide, T. & Suomalainen, A. High mitochondrial DNA copy number has detrimental effects in mice. Hum. Mol. Genet. 19, 2695-705 (2010). 20413656 | 20413656 |
| 1912 | PEO1 | ARP36483_P050 | Wang, J.-T., Xu, X., Alontaga, A. Y., Chen, Y. & Liu, Y. Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction. Cell Rep. 7, 848-58 (2014). 24746816 | 24746816 |
| 1913 | PERIOSTIN | OAPC00052 | Increased Hemodynamic Load in Early Embryonic Stages Alters Endocardial to Mesenchymal Transition. Front Physiol. 8, 56 (2017). 28228731 | 28228731 |
| 1914 | PET | OKWB00279 | The Basophil IL-18 Receptor Precisely Regulates the Host Immune Response and Malaria-Induced Intestinal Permeability and Alters Parasite Transmission to Mosquitoes without Effect on Gametocytemia.Immunohorizons630-64168August2022 | 35985797 |
| 1915 | PEX3 | ARP46090_T100 | Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome. J. Biol. Chem. 291, 24231-24246 (2016). 27679530 | 27679530 |
| 1916 | PFAS | ARP46181_P050 | French, J. B. et al. Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome. Proc. Natl. Acad. Sci. U. S. A. 110, 2528-33 (2013). 23359685 | 23359685 |
| 1917 | Pfkfb2 | ARP48454_P050 | Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat Hearts. Anesth Analg 2020 1 130 37-48 31274599 | 31274599 |
| 1918 | PFKFB3 | OABF01219 | Glycolysis and oxidative phosphorylation are essential for purinergic receptor-mediated angiogenic responses in vasa vasorum endothelial cells. Am. J. Physiol., Cell Physiol. 312, C56-C70 (2017). 27856430 | 27856430 |
| 1919 | PFKL | ARP45774_T100 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 1920 | PGA3 | OKEH03169 | Novel urinary protein biomarker panel for early diagnosis of gastric cancer. Br J Cancer. 123, 1656-1664 (2020). 32934343 | 32934343 |
| 1921 | PGC-1a | ARP31507_P050 | Lee, Y. H. et al. Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazone. J. Proteome Res. 12, 2933-45 (2013). 23659346 | 23659346 |
| 1922 | PGS1 | ARP48895_T100 | Kiebish, M. A. et al. Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency. J. Biol. Chem. 287, 25086-97 (2012). 22584571 | 22584571 |
| 1923 | PGS1 | ARP48895_T100 | Croston, T. L. et al. Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart. Life Sci. 93, 313-22 (2013). 23872101 | 23872101 |
| 1924 | PHACTR1 | ARP55397_P050 | Allain, B. et al. Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells. Cell. Signal. 24, 214-23 (2012). 21939755 | 21939755 |
| 1925 | PHD1 | ARP31419_P050 | Tennant, D. A. & Gottlieb, E. HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression. J. Mol. Med. (Berl). 88, 839-49 (2010). 20383689 | 20383689 |
| 1926 | PHD1 | ARP39775_P050 | Tennant, D. A. et al. Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death. Oncogene 28, 4009-21 (2009). 19718054 | 19718054 |
| 1927 | PHLDA2 | ARP58237_P050 | Dai, H. et al. TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma. Carcinogenesis 33, 30-40 (2012). 22021909 | 22021909 |
| 1928 | PHOSPHO-GSK3 BETA | OKAG01955 | The role of hippocampal insulin signaling on postoperative cognitive dysfunction in an aged rat model of abdominal surgery. Life Sci. 162, 87-94 (2016). 27561842 | 27561842 |
| 1929 | PHOSPHO-SNAI1 | OKAG01873 | Colorectal cancer-promoting activity of the senescent peritoneal mesothelium. Oncotarget. 6, 29178-95 (2015). 26284488 | 26284488 |
| 1930 | PHOSPHO-STAT1 | OKAG02056 | Inhibition of Src homology 2 domain containing protein tyrosine phosphatase as the possible mechanism of metformin-assisted amelioration of obesity induced insulin resistance in high fat diet fed C57BL/6J mice. Biochem. Biophys. Res. Commun. (2017). 28389241 | 28389241 |
| 1931 | PICP | OKEH00541 | Gelatin-Alginate Coacervates Optimized by DOE to Improve Delivery of bFGF for Wound Healing.PharmaceuticsNULL1312December2021 | 34959393 |
| 1932 | Pitx2 | ARP35634_T100 | Hatou, S. et al. Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/beta-catenin signaling. Stem Cells Dev. 22, 828-39 (2013). 22974347 | 22974347 |
| 1933 | PKD2 | OAEB01480 | Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. J. Am. Soc. Nephrol. 27, 2645-57 (2016). 26839368 | 26839368 |
| 1934 | PKLR | OAGA00912 | AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency. Blood. 130, 1347-1356 (2017). 28760888 | 28760888 |
| 1935 | PLA2G5 | ARP41429_P050 | PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation. J. Leukoc. Biol. 100, 131-41 (2016). 26936936 | 26936936 |
| 1936 | PLCB2 | OAAB05844 | TAS2R16 Activation Suppresses LPS-Induced Cytokine Expression in Human Gingival Fibroblasts. Front Immunol. 12, 726546 (2022). 34975834 | 34975834 |
| 1937 | PLS3 | ARP56623_P050 | Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy. Mol Ther Methods Clin Dev. 9, 81-89 (2018). 29552580 | 29552580 |
| 1938 | PMAP23 | OKWB00337 | Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis. Int J Mol Sci. 21, NULL (2020). 32722502 | 32722502 |
| 1939 | PMEL | ARP46802_T100 | Indication of Premelanosome Protein (PMEL) Expression Outside of Pigmented Bovine Skin Suggests Functions Beyond Eumelanogenesis. Genes (Basel). 11, NULL (2020). 32668786 | 32668786 |
| 1940 | PMS2 | OAAF04086 | A rapidly growing human papillomavirus-positive oral tongue squamous cell carcinoma in a 21-year old female: A case report. Oncol Lett. 15, 7702-7706 (2018). 29849799 | 29849799 |
| 1941 | PMSG | OPPA01037 | Troder SE, Ebert LK, Butt L, Assenmacher S, Schermer B, Zevnik B. An optimized electroporation approach for efficient CRISPR/Cas9 genome editing in murine zygotes. PloS one. 2018;13(5):e0196891. Epub 2018/05/04. doi: 10.1371/journal.pone.0196891. 29723268 | 29723268 |
| 1942 | PMSG | | A simple and economic protocol for efficient in vitro fertilization using cryopreserved mouse sperm. PLoS One 2021 10 16 e0259202 34710162 | 34710162 |
| 1943 | PNLIP | ARP33852_T100 | Itoh, M. et al. Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation. Differentiation. 80, 118-22 20538404 | 20538404 |
| 1944 | PNPLA3 | OKCD01974 | Validating candidate biomarkers for different stages of non-alcoholic fatty liver disease. Medicine (Baltimore). 99, e21463 (2020). 32898995 | 32898995 |
| 1945 | PODXL | OKEH03213 | Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells.JCI InsightNULLNULLNULLSeptember2022 | 36107633 |
| 1946 | POGZ | ARP44223_P050 | The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells. Cells 2021 10 10 NULL 34685704 | 34685704 |
| 1947 | POLE4 | ARP39392_P050 | MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway. Mol Biol Cell. 24, 42-55 (2013). 23135998 | 23135998 |
| 1948 | Polg | ARP48580_P050 | Mancini, C. et al. Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. BMC Med. Genomics 6, 22 (2013). 23777634 | 23777634 |
| 1949 | POLRMT | ARP48659_P050 | Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression. PLoS Genet. 16, e1009118 (2020). 33075064 | 33075064 |
| 1950 | POMC | OKEH03680 | Kim, Suhyeon, Ki-Bae Hong Singeun Kim, Hyung Joo Suh, Kyungae Jo. Creatine and taurine mixtures alleviate depressive-like behaviour in Drosophila melanogaster and mice via regulating Akt and ERK/BDNF pathways. Sci Rep. 2020 Jul 9;10(1):11370. 32647316 | 32647316 |
| 1951 | POU4F2 | ARP38501_P050 | Tucker, B. A., Anfinson, K. R., Mullins, R. F., Stone, E. M. & Young, M. J. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl. Med. 2, 16-24 (2013). 23283489 | 23283489 |
| 1952 | POU5F1 | P100956_T100 | Oct-4B isoform is differentially expressed in breast cancer cells: hypermethylation of regulatory elements of Oct-4A suggests an alternative promoter and transcriptional start site for Oct-4B transcription. Biosci Rep. 31, 109-15 (2011). 20433421 | 20433421 |
| 1953 | POU5F1 | P100956_T100 | Kaeffer, B. et al. Non-invasive exploration of neonatal gastric epithelium by using exfoliated epithelial cells. PLoS One 6, e25562 (2011). 22028779 | 22028779 |
| 1954 | POU5F1 | P100956_T100 | Li, Y. et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a dNp63+ cytotrophoblast stem cell state. Development 140, 3965-76 (2013). 24004950 | 24004950 |
| 1955 | PPAP2A | ARP42721_T100 | Evseenko, D. et al. Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment. PLoS One 8, e63718 (2013). 23696850 | 23696850 |
| 1956 | PPARA | ARP34068_P050 | Gu, Q. et al. Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology. doi:10.1002/hep.27356 (2014). 25130427 | 25130427 |
| 1957 | PPARD | ARP37889_T100 | Ares-Carrasco, S. et al. Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPARa in the associated hypertrophy. J. Proteomics 75, 1816-29 (2012). 22234359 | 22234359 |
| 1958 | PPARD | ARP37889_T100 | Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy). Hum. Mol. Genet. 25, 2194-2207 (2016). 27005420 | 27005420 |
| 1959 | PPARD | ARP37889_T100 | Predictive Role of Biopsy Based Biomarkers for Radiotherapy Treatment in Rectal Cancer. J Pers Med. 10, NULL (2020). 33066317 | 33066317 |
| 1960 | PPARD | ARP38765_T100 | Pregnancy-associated changes of peroxisome proliferator-activated receptor delta (PPARD) and cytochrome P450 family 21 subfamily A member 2 (CYP21A2) expression in the bovine corpus luteum. J Reprod Dev. 66, 205-213 (2020). 32037375 | 32037375 |
| 1961 | PPARD | ARP54577_P050 | Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ. Nat Commun 2022 1 13 2665 35562376 | 35562376 |
| 1962 | PPAR-delta | ARP37889_T100 | Yang, L. et al. Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells. Oncogene 29, 516-26 (2010). 19935699 | 19935699 |
| 1963 | PPAR-delta | ARP37889_T100 | Yang, L. et al. Biological function and prognostic significance of peroxisome proliferator-activated receptor d in rectal cancer. Clin. Cancer Res. 17, 3760-70 (2011). 21531809 | 21531809 |
| 1964 | PPAR-gamma | OAEB02003 | Spelman, K. et al. Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide. Int. Immunopharmacol. 9, 1260-4 (2009). 19712756 | 19712756 |
| 1965 | PPARGC1A | ARP39015_P050 | Tumor protein Tctp regulates axon development in the embryonic visual system. Development. 143, 1134-48 (2016). 26903505 | 26903505 |
| 1966 | PPP1R14A | ARP63944_P050 | Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response. EBioMedicine. 9, 45-60 (2016). 27333042 | 27333042 |
| 1967 | PPP2R2B | OAAB05193 | Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells. Cancer Sci. 107, 955-62 (2016). 27116120 | 27116120 |
| 1968 | PPP2R3B | ARP42370_P050 | The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene. Sci Transl Med. 8, 369ra177 (2016). 27974665 | 27974665 |
| 1969 | PPP2R5E | ARP56694_P050 | Division of labour between PP2A-B56 isoforms at the centromere and kinetochore. Elife. 8, (2019). 30829571 | 30829571 |
| 1970 | PPP3CC | ARP64741_P050 | Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation. Cell Rep. 26, 2929-2941.e5 (2019). 30865884 | 30865884 |
| 1971 | PRAME | ARP55981_P050 | A novel testis-specific protein, PRAMEY, is involved in spermatogenesis in cattle. Reproduction. (2017). 28356500 | 28356500 |
| 1972 | PRAME | ARP55982_P050 | Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis. Cell Biosci. 11, 102 (2021). 34074333 | 34074333 |
| 1973 | PRC1 | OAAN02101 | Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models. EMBO Mol Med. 13, e13144 (2021). 33660397 | 33660397 |
| 1974 | PRDM1 | P100596_P050 | VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. Cancer Cell. 28, 210-24 (2015). 26212250 | 26212250 |
| 1975 | PRDX1 | ARP48454_P050 | Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens. Sci Rep. 8, 1320 (2018). 29358656 | 29358656 |
| 1976 | PRDX1 | OAEB00418 | A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells. J Food Drug Anal 2021 4 29 638-652 35649133 | 35649133 |
| 1977 | Prealbumin | OKIA00111 | Finn, JD et al. A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing. Cell Rep. 22(9):2227-2235. doi: 10.1016/j.celrep.2018.02.014 (2018). 29490262 | 29490262 |
| 1978 | Prealbumin | OKIA00159 | Finn, JD et al. A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing. Cell Rep. 22(9):2227-2235. doi: 10.1016/j.celrep.2018.02.014 (2018). 29490262 | 29490262 |
| 1979 | PRKN | ARP43038_P050 | Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene. Curr Genomics. 15, 203-16 (2014). 24955028 | 24955028 |
| 1980 | PRKN | ARP43038_P050 | Alternative splicing generates different parkin protein isoforms: evidences in human, rat, and mouse brain. Biomed Res Int. 2014, 690796 (2014). 25136611 | 25136611 |
| 1981 | PRKN | ARP43038_P050 | Ubiquitination as a Mechanism To Transport Soluble Mycobacterial and Eukaryotic Proteins to Exosomes. J Immunol. 195, 2722-30 (2015). 26246139 | 26246139 |
| 1982 | PRKRA | ARP40475_P050 | Yoshida, K. et al. Interaction between PKR and PACT mediated by LPS-inducible NF-κB in human gingival cells. J. Cell. Biochem. 113, 165-73 (2012). 21882225 | 21882225 |
| 1983 | PRL | OAAB01514 | Reichenbach, A., Steyn, F. J., Sleeman, M. W. & Andrews, Z. B. Ghrelin receptor expression and colocalization with anterior pituitary hormones using a GHSR-GFP mouse line. Endocrinology 153, 5452-66 (2012). 22962259 | 22962259 |
| 1984 | PRL | OKCD06890 | Differences in hormone levels around parturition in Hanwoo cattle (Bos taurus coreanae) following artificial insemination and embryo transfer.Vet Med Sci1258-126383May2022 | 35193169 |
| 1985 | PRMT2 | ARP40195_P050 | Zhong, J. et al. Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein. Oncogene (2013). doi:10.1038/onc.2013.500 24292672 | 24292672 |
| 1986 | PRMT2 | ARP40196_T100 | Zhong, J. et al. Identification and expression analysis of a novel transcript of the human PRMT2 gene resulted from alternative polyadenylation in breast cancer. Gene 487, 1-9 (2011). 21820040 | 21820040 |
| 1987 | PRMT2 | ARP40196_T100 | Zhong, J. et al. Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma. FEBS J. 279, 316-35 (2012). 22093364 | 22093364 |
| 1988 | PRMT2 | ARP40196_T100 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 1989 | PRMT2 | ARP40196_T100 | Burton, A. et al. Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 5, 687-701 (2013). 24183668 | 24183668 |
| 1990 | PRMT2 | ARP40196_T100 | Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl. Dev Cell. 45, 262-275.e8 (2018). 29689199 | 29689199 |
| 1991 | Prp19 | ARP43158_T100 | Song, G., Cui, Y., Zhong, N. & Han, J. Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium. J. Clin. Pathol. 62, 802-7 (2009). 19403515 | 19403515 |
| 1992 | PRSS21 | ARP53665_P050 | The serine protease testisin is present on the surface of capacitated stallion spermatozoa and interacts with key zona pellucida binding proteins. Andrology. 7, 199-212 (2019) 30549223 | 30549223 |
| 1993 | PRSS33 | OAAF06983 | Proteinase-Mediated Macrophage Signaling in Psoriatic Arthritis. Front Immunol. 11, 629726 (2021) 33763056 | 33763056 |
| 1994 | PRSS33 | OKCD02115 | Proteinase-Mediated Macrophage Signaling in Psoriatic Arthritis. Front Immunol. 11, 629726 (2021) 33763056 | 33763056 |
| 1995 | PSAP | OKEH06059 | Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis. Reproduction 2021 5 161 513-522 33666569 | 33666569 |
| 1996 | PSAT | ARP46303_P050 | Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer. Oncology. 89, 351-9 (2015). 26439504 | 26439504 |
| 1997 | PSAT1 | ARP46303_P050 | Yang, Y. et al. PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells. Int. J. Cancer (2014). doi:10.1002/ijc.29150 25142862 | 25142862 |
| 1998 | PSEN1 | ARP58941_P050 | Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain. 138, 2005-19 (2015). 25981964 | 25981964 |
| 1999 | PSMA1 | ARP40417_P050 | Cron, K. R. et al. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PLoS One 8, e73710 (2013). 24040035 | 24040035 |
| 2000 | PSMC5 | ARP38192_T100 | Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster. Aging Cell. 11, 634-43 (2012). 22507075 | 22507075 |
| 2001 | PSTS1 | OACA02044 | Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection. Microb Cell Fact. 18, 11 (2019). 30660186 | 30660186 |
| 2002 | PTBP1 | ARP40422_P050 | Clower, C. V et al. The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proc. Natl. Acad. Sci. U. S. A. 107, 1894-9 (2010). 20133837 | 20133837 |
| 2003 | PTCH1 | ARP44249_P050 | Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma. Mol. Cancer Ther. 15, 1095-105 (2016). 26839306 | 26839306 |
| 2004 | PTCH1 | ARP44249_P050 | Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma. BMC Genomics. 18, 708 (2017). 28886691 | 28886691 |
| 2005 | PTDSS1 | ARP47068_P050 | Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 177, 881-895.e17 (2019). 31051106 | 31051106 |
| 2006 | PTDSS2 | ARP49960_P050 | Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 177, 881-895.e17 (2019). 31051106 | 31051106 |
| 2007 | PTEN | OKEH02377 | Circular RNA circENTPD7 suppresses the accumulation of PTEN to promote cell proliferation in non-small cell lung cancer.Genet Mol Biole20220023453August2022 | 35993557 |
| 2008 | PTGER1 | OABF01677 | The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation. BJU Int. 124, 883-891 (2019). 31166645 | 31166645 |
| 2009 | PtGR1 | OAAB03341 | Vitturi, D. A. et al. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. J. Biol. Chem. 288, 25626-37 (2013). 23878198 | 23878198 |
| 2010 | PTH | OKEH00642 | Correlation of serum PTH level and fracture healing speed in elderly patients with hip fracture. J Orthop Surg Res. 14, 361 (2019). 31718681 | 31718681 |
| 2011 | Pthlh | ARP33885_T100 | Zhao, C.-M. et al. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regul. Pept. 192-193C, 35-44 (2014). 25160855 | 25160855 |
| 2012 | PTHLH | ARP33885_T100 | Role of the Parathyroid Hormone Type 1 Receptor (PTH1R) as a Mechanosensor in Osteocyte Survival. J Bone Miner Res. 30, 1231-44 (2015). 25529820 | 25529820 |
| 2013 | PTHrP | ARP33885_T100 | Müller, M., Gagiannis, S., Nawroth, P. P., Brune, M. & Schilling, T. Activation of the receptor for parathyroid hormone and parathyroid hormone related protein induces apoptosis via the extrinsic and intrinsic signaling pathway. Int. J. Mol. Med. 24, 373-80 (2009). 19639230 | 19639230 |
| 2014 | PTOV1 | ARP50614_P050 | Youn, H.-S., Park, U.-H., Kim, E.-J. & Um, S.-J. PTOV1 antagonizes MED25 in RAR transcriptional activation. Biochem. Biophys. Res. Commun. 404, 239-44 (2011). 21110951 | 21110951 |
| 2015 | PWP2 | ARP45822_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2016 | PYCARD | OKEH01695 | NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation. Int J Inflam 2022 NULL 2022 2337363 35265316 | 35265316 |
| 2017 | QA | OKCD02284 | Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease. Am J Pathol. 189, 1435-1450 (2019). 30980800 | 30980800 |
| 2018 | Quinolinic acid | OKCD02284 | Abdur Rahman, Muddanna S. Rao & Khalid M. Khan. Intraventricular infusion of quinolinic acid impairs spatial learning and memory in young rats: a novel mechanism of lead-induced neurotoxicity. J Neuroinflammation. 15, 263 (2018). PMC6137743 | PMC6137743 |
| 2019 | RAB11A | ARP63742_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
| 2020 | RAB14 | AVARP13107_P050 | Kanzaki, H. et al. Identification of direct targets for the miR-17-92 cluster by proteomic analysis. Proteomics 11, 3531-9 (2011). 21751348 | 21751348 |
| 2021 | RAB14 | AVARP13107_P050 | Farhoud, M. H. et al. Impaired ubiquitin-proteasome-mediated PGC-1a protein turnover and induced mitochondrial biogenesis secondary to complex-I deficiency. Proteomics 12, 1349-62 (2012). 22589185 | 22589185 |
| 2022 | RAB14 | AVARP13107_P050 | Rab14 regulation of claudin-2 trafficking modulates epithelial permeability and lumen morphogenesis. Mol Biol Cell. 25, 1744-54 (2014). 24694596 | 24694596 |
| 2023 | RAB14 | AVARP13107_P050 | Rab11-FIP1A regulates early trafficking into the recycling endosomes. Exp Cell Res. 340, 259-73 (2016). 26790954 | 26790954 |
| 2024 | RAB22A | ARP57434_P050 | Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells. EMBO Rep. 17, 1753-1765 (2016). 27861124 | 27861124 |
| 2025 | RAB31 | ARP43518_T100 | Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency. Blood Adv 2022 NULL NULL NULL 35839075 | 35839075 |
| 2026 | RAB35 | ARP52267_P050 | Kley, R. A. et al. A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients. Mol. Cell. Proteomics 12, 215-27 (2013). 23115302 | 23115302 |
| 2027 | RAB5A | ARP56563_P050 | Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells. J Extracell Vesicles. 6, 1294368 (2017). 28326171 | 28326171 |
| 2028 | RABGGTA | ARP49163_P050 | Arora, D. K., Syed, I., Machhadieh, B., McKenna, C. E. & Kowluru, A. Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic beta cells. Islets 4, 354-8 (2012). 23114750 | 23114750 |
| 2029 | RAD23A | ARP42211_T100 | USF-1 is critical for maintaining genome integrity in response to UV-induced DNA photolesions. PLoS Genet. 8, e1002470 (2012). 22291606 | 22291606 |
| 2030 | RAGE | ARP56743_P050 | Tafani, M. et al. Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B. Carcinogenesis 32, 1167-75 (2011). 21642357 | 21642357 |
| 2031 | RAPGEF3 | ARP52140_P050 | EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1. J Cell Sci. 129, 2599-612 (2016). 27206858 | 27206858 |
| 2032 | RAPGEF3 | ARP52140_P050 | Cytoskeleton regulators CAPZA2 and INF2 associate with CFTR to control its plasma membrane levels under EPAC1 activation. Biochem J. 477, 2561-2580 (2020) 32573649 | 32573649 |
| 2033 | RAPGEF3 | ARP52140_P050 | Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids.CellsNULL1115July2022 | 35892592 |
| 2034 | RASD1 | OKEH06148 | Chronic Systemic Dexamethasone Regulates the Mineralocorticoid/Glucocorticoid Pathways Balance in Rat Ocular Tissues.Int J Mol SciNULL233January2022 | 35163201 |
| 2035 | RASSF1 | OKCD02023 | Effects of Propolis and Phenolic Acids on Triple-Negative Breast Cancer Cell Lines: Potential Involvement of Epigenetic Mechanisms. Molecules. 25, (2020). 32178333 | 32178333 |
| 2036 | RASSF7 | ARP34390_T100 | Lim, S. et al. Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration. Int. J. Biochem. Cell Biol. 45, 1784-93 (2013). 20629633 | 20629633 |
| 2037 | RB1 | ARP58065_P050 | Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells. Oncotarget. 9, 27835-27850 (2018). 29963241 | 29963241 |
| 2038 | RB1 | OAAB16108 | Mathematical modelling of breast cancer cells in response to endocrine therapy and Cdk4/6 inhibition. J R Soc Interface. 17, 20200339 (2020). 32842890 | 32842890 |
| 2039 | RBCK1 | OAAB15606 | Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC). Bioorg Med Chem. 26, 1179-1188 (2018). 29246782 | 29246782 |
| 2040 | RBFOX1 | ARP40920_P050 | Fogel, B. L. et al. RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum. Mol. Genet. 21, 4171-86 (2012). 22730494 | 22730494 |
| 2041 | RBM28 | ARP40890_P050 | Nousbeck, J. et al. Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis. Am. J. Hum. Genet. 82, 1114-21 (2008). 18439547 | 18439547 |
| 2042 | RBM38 | ARP40862_P050 | Therapeutic modulation of RNA-binding protein Rbm38 facilitates re-endothelialization after arterial injury. Cardiovasc Res. 115, 1804-1810 (2019). 30843048 | 30843048 |
| 2043 | RBM38 | ARP40863_P050 | Feldstein, O., Ben-Hamo, R., Bashari, D., Efroni, S. & Ginsberg, D. RBM38 is a direct transcriptional target of E2F1 that limits E2F1-induced proliferation. Mol. Cancer Res. 10, 1169-77 (2012). 22798430 | 22798430 |
| 2044 | RBMX | ARP61802_P050 | Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One. 8, e58456 (2013). 23520512 | 23520512 |
| 2045 | RBP | OKBB00339 | Paik, J. et al. Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice. J. Biol. Chem. 289, 15104-17 (2014). 24711451 | 24711451 |
| 2046 | RBP1 | ARP33088_T100 | Kondou, H. et al. Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development. Hepatol. Res. (2013). doi:10.1111/hepr.12069 23607685 | 23607685 |
| 2047 | RBP2 | ARP63707_P050 | Lee, J.-H., You, J., Dobrota, E. & Skalnik, D. G. Identification and characterization of a novel human PP1 phosphatase complex. J. Biol. Chem. 285, 24466-76 (2010). 20516061 | 20516061 |
| 2048 | RBX1 | AVARP03042_T100 | Maerki, S. et al. The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J. Cell Biol. 187, 791-800 (2009). 19995937 | 19995937 |
| 2049 | RCAN1 | ARP38457_P050 | Voronov, I. et al. The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis. J. Bone Miner. Res. 28, 108-18 (2013). 22865292 | 22865292 |
| 2050 | RCOR1 | ARP39178_T100 | Packer, A. N., Xing, Y., Harper, S. Q., Jones, L. & Davidson, B. L. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington’s disease. J. Neurosci. 28, 14341-6 (2008). 19118166 | 19118166 |
| 2051 | RDBP | ARP40431_P050 | Schulz, M. et al. Quantitative phosphoproteomic analysis of early alterations in protein phosphorylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Proteome Res. 12, 866-82 (2013). 23298284 | 23298284 |
| 2052 | RDH12 | OAMA02173 | In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids. Biomed Opt Express 2022 6 13 3476-3492 35781966 | 35781966 |
| 2053 | RDh8 | ARP38054_P050 | In situ autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids. Biomed Opt Express 2022 6 13 3476-3492 35781966 | 35781966 |
| 2054 | REN | ARP41409_T100 | Kumai, Y., Bernier, N. J. & Perry, S. F. Angiotensin-II promotes Na+ uptake in larval zebrafish, Danio rerio, in acidic and ion-poor water. J. Endocrinol. 220, 195-205 (2014). 24301614 | 24301614 |
| 2055 | REN | ARP41409_T100 | STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects. JCI Insight. NULL, NULL (2020). 33301424 | 33301424 |
| 2056 | REN2 | OACA02177 | Salt-losing nephropathy in mice with a null mutation of the Clcnk2 gene. Acta Physiol (Oxf). 27421685 | 27421685 |
| 2057 | REN2 | OACA02177 | Targeting VE-PTP phosphatase protects the kidney from diabetic injury. J Exp Med. 216, 936-949 (2019). 30886059 | 30886059 |
| 2058 | REST | ARP32086_P050 | Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury. Cell Death Dis. 11, 138 (2020). 32080178 | 32080178 |
| 2059 | REST | ARP32478_P050 | Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins. J. Neurosci. 35, 16443-9 (2015). 26674869 | 26674869 |
| 2060 | RETREG1 | ARP44827_T100 | FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Mol Oncol. 13, 792-810 (2019). 30556279 | 30556279 |
| 2061 | RFFL | ARP42986_P050 | Hanuszkiewicz, A. et al. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses. J. Biol. Chem. 289, 19231-44 (2014). 24841205 | 24841205 |
| 2062 | RFP Tag | OAEA00012 | Loosening ER-Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain. Cells. 10, NULL (2021) 34440738 | 34440738 |
| 2063 | RG9MTD1 | ARP40877_P050 | CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J. 35, 2566-2583 (2016). 27797820 | 27797820 |
| 2064 | RGGTA | ARP49163_P050 | Lachance, V. et al. Regulation of beta2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor. J. Biol. Chem. 286, 40802-13 (2011). 21990357 | 21990357 |
| 2065 | RGS14 | OAAF04168 | Regulator of G protein signalling 14 attenuates cardiac remodelling through the MEK-ERK1/2 signalling pathway. Basic Res Cardiol. 111, 47 (2016). 27298141 | 27298141 |
| 2066 | RGS16 | ARP34040_T100 | Timmusk, S. et al. Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein. J. Gen. Virol. 90, 2425-36 (2009). 19570954 | 19570954 |
| 2067 | RGS4 | OKEI00172 | Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells. Environ Health Perspect. 129, 77007 (2021) 34328791 | 34328791 |
| 2068 | RHBDL2 | ARP47356_P050 | Cheng, T.-L. et al. Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing. J. Invest. Dermatol. 131, 2486-94 (2011). 21833011 | 21833011 |
| 2069 | RHBDL2 | OACA03576 | Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice.J Bone Miner Res1812-1823359September2020 | 32329910 |
| 2070 | RhBG | ARP49502_P050 | Han, K.-H. et al. Expression of the ammonia transporter family member, Rh B Glycoprotein, in the human kidney. Am. J. Physiol. Renal Physiol. 304, F972-81 (2013). 23324176 | 23324176 |
| 2071 | RHOT1 | ARP44817_P050 | Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. J Cell Biol. 218, 1871-1890 (2019). 31068376 | 31068376 |
| 2072 | RHOT1 | ARP44818_P050 | Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models. Cell Metab. 30, 1131-1140.e7 (2019). 31564441 | 31564441 |
| 2073 | RHOX8 | ARP36806_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
| 2074 | RHOX8 | ARP36807_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
| 2075 | RHOX8 | ARP37849_P050 | Welborn, J.P. et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015 Jul; 93(1): 8. 25972016 | 25972016 |
| 2076 | RINL | OAAB08343 | Allen, M. A. et al. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Elife 3, e02200 (2014). 24867637 | 24867637 |
| 2077 | RIPK3 | ARP31513_T100 | Mesenchymal Stem/Stromal Cells and their Extracellular Vesicle Progeny Decrease Injury in Poststenotic Swine Kidney Through Different Mechanisms. Stem Cells Dev. 29, 1190-1200 (2020) 32657229 | 32657229 |
| 2078 | RIPK3 | ARP32835_P050 | Analysis of necroptotic proteins in failing human hearts. J Transl Med. 15, 86 (2017). 28454582 | 28454582 |
| 2079 | RIPK3 | ARP32835_P050 | Different signalling in infarcted and non-infarcted areas of rat failing hearts: A role of necroptosis and inflammation. J Cell Mol Med. 23, 6429-6441 (2019). 31328381 | 31328381 |
| 2080 | RIPK3 | OKCD02851 | Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis Pathway. Int J Mol Sci. 22, NULL (2021) 34445504 | 34445504 |
| 2081 | RNF146 | ARP43340_T100 | Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents. EMBO Rep. 20, NULL (2019). 30940648 | 30940648 |
| 2082 | RNF146 | ARP43340_T100 | Binghai Zhou, et al. Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma. 6530-6543 (2020). 32483468 | 32483468 |
| 2083 | RNF31 | ARP43241_P050 | Sieber, S. et al. Sharpin contributes to TNFa dependent NFκB activation and anti-apoptotic signalling in hepatocytes. PLoS One 7, e29993 (2012). 22253853 | 22253853 |
| 2084 | RNF31 | ARP43241_P050 | Smit, J. J. et al. The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-44 (2012). 22863777 | 22863777 |
| 2085 | RNF31 | ARP43241_P050 | Blackwell, K. et al. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation. Mol. Cell. Biol. 33, 1901-15 (2013). 23459942 | 23459942 |
| 2086 | RNF31 | ARP43241_P050 | Liu, S. et al. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife 2, e00785 (2013). 23951545 | 23951545 |
| 2087 | RNF31 | ARP43241_P050 | Queisser, M. A. et al. HOIL-1L Functions as the PKCz Ubiquitin Ligase to Promote Lung Tumor Growth. (2014). 25118570 | 25118570 |
| 2088 | RNF31 | ARP43241_P050 | SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 16, 2271-80 (2016). 27545878 | 27545878 |
| 2089 | RNF31 | ARP43241_P050 | The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. (2017). 28258062 | 28258062 |
| 2090 | RNF31 | ARP43241_P050 | Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 39, e103303 (2020). 33215740 | 33215740 |
| 2091 | RNF8 | ARP40071_T100 | The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny. Biol Reprod. 89, 85 (2013). 23986570 | 23986570 |
| 2092 | ROBO2 | ARP45396_P050 | Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nat Commun. 11, 5171 (2020). 33057002 | 33057002 |
| 2093 | ROBO2 | OAGA00059 | Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function. Cell Rep 2021 3 37 109828 34686348 | 34686348 |
| 2094 | ROCK1 | OKEH06554 | LncRNA LINK-A regulates ROCK1 expression in early-stage pancreatic adenocarcinoma. Exp Ther Med. 19, 1933-1939 (2020). 32104251 | 32104251 |
| 2095 | ROCK1 | OKEH06554 | Long non-coding RNA CCHE1 participates in postoperative distant recurrence but not local recurrence of osteosarcoma possibly by interacting with ROCK1. BMC Musculoskelet Disord. 21, 462 (2020). 32660450 | 32660450 |
| 2096 | ROMO1 | ARP58431_P050 | Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020, 4717258 (2020). 31998437 | 31998437 |
| 2097 | ROMO1 | ARP58431_P050 | Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 18, 210 (2021) 34530854 | 34530854 |
| 2098 | ROR1 | OABF00363 | Smartphone based on-chip fluorescence imaging and capillary flow velocity measurement for detecting ROR1+ cancer cells from buffy coat blood samples on dual-layer paper microfluidic chip. Biosens Bioelectron. 153, 112042 (2020) 32056660 | 32056660 |
| 2099 | RORA | OAAN02076 | Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons. Mol Autism. 9, 6 (2018). 29423132 | 29423132 |
| 2100 | RORC | OAEB00974 | Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. Mucosal Immunol. 8, 1047-59 (2015). 25603827 | 25603827 |
| 2101 | RPB2 | ARP32456_P050 | Lee, J.-H. & Skalnik, D. G. Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes. Mol. Cell. Biol. 28, 609-18 (2008). 17998332 | 17998332 |
| 2102 | RPH3A | ARP59498_P050 | PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury. Cell Rep. 19, 2586-2597 (2017). 28636945 | 28636945 |
| 2103 | RPH3A | ARP59498_P050 | Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization. J Immunol. 204, 1012-1021 (2020). 31924649 | 31924649 |
| 2104 | RPL13 | ARP40217_P050 | Hartl, T. A. et al. Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila. Genetics 194, 101-15 (2013). 23436180 | 23436180 |
| 2105 | RPL32 | ARP40219_T100 | Mobine, H. R. et al. Encapsulated pheochromocytoma cells secrete potent noncatecholamine factors. Tissue Eng. Part A 15, 1719-28 (2009). 19125641 | 19125641 |
| 2106 | RPL5 | ARP56126_P050 | Genome-Wide Identification, Evolution and Expression of the Complete Set of Cytoplasmic Ribosomal Protein Genes in Nile Tilapia. Int J Mol Sci. 21, (2020). 32059409 | 32059409 |
| 2107 | RPL8 | ARP40215_T100 | Wong, C. C., Traynor, D., Basse, N., Kay, R. R. & Warren, A. J. Defective ribosome assembly in Shwachman-Diamond syndrome. Blood 118, 4305-12 (2011). 21803848 | 21803848 |
| 2108 | RPL8 | ARP40215_T100 | Adenylyl cyclase A mRNA localized at the back of cells is actively translated in live chemotaxing Dictyostelium. J Cell Sci. 131, NULL (2018). 29618632 | 29618632 |
| 2109 | Rpn10 | ARP58060_P050 | Ghi, P., Di Brisco, F., Dallorto, D., Osella, M. C. & Orsetti, M. Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus. Mech. Ageing Dev. 130, 320-7 (2009). 19428450 | 19428450 |
| 2110 | RPN2 | ARP45400_P050 | Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma. Int. J. Oncol. 50, 448-456 (2017). 28035352 | 28035352 |
| 2111 | RPS15 | ARP56185_P050 | Assessing the translational landscape of myogenic differentiation by ribosome profiling. Nucleic Acids Res. 43, 4408-28 (2015). 25873627 | 25873627 |
| 2112 | RPS16 | ARP33535_T100 | Okada, K. et al. Expression analysis of MIF4GD in the rat testis. J. Reprod. Dev. 57, 256-61 (2011). 21157122 | 21157122 |
| 2113 | RPS16 | ARP33535_T100 | Sugihara, Y. et al. Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis. Gene 521, 91-9 (2013). 23500592 | 23500592 |
| 2114 | RPS2 | ARP63572_P050 | Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Plant Cell. 25, 1523-40 (2013). 23667124 | 23667124 |
| 2115 | RPS2 | ARP63572_P050 | Zfrp8/PDCD2 Interacts with RpS2 Connecting Ribosome Maturation and Gene-Specific Translation. PLoS ONE. 11, e0147631 (2016). 26807849 | 26807849 |
| 2116 | RPS2 | ARP63572_P050 | Deletion of the N-Terminal Domain of Yeast Eukaryotic Initiation Factor 4B Reprograms Translation and Reduces Growth in Urea. Front Mol Biosci. 8, 787781 (2022). 35047555 | 35047555 |
| 2117 | RPS2 | ARP63573_P050 | Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation. RNA. 23, 798-810 (2017). 28223409 | 28223409 |
| 2118 | RPS28 | ARP65601_P050 | A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice. Cell Rep. 29, 3816-3824.e4 (2019). 31851915 | 31851915 |
| 2119 | RPS6KA2 | ARP56170_P050 | Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism.iScience104823258August2022 | 35992092 |
| 2120 | RPS6KB1 | OAAF07416 | Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment. iScience. 24, 103497 (2021). 34934919 | 34934919 |
| 2121 | RRM1 | ARP46029_T100 | Chung, W.-G., Sandoval, M. A., Sloat, B. R., Lansakara-P, D. S. P. & Cui, Z. Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1. J. Control. Release 157, 132-40 (2012). 21851843 | 21851843 |
| 2122 | RRM1 | ARP46029_T100 | Wonganan, P. et al. Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells. Cancer Biol. Ther. 13, 908-14 (2012). 22785206 | 22785206 |
| 2123 | RRM1 | ARP46029_T100 | Zhu, S. et al. The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression. Biomaterials 34, 2327-39 (2013). 23261218 | 23261218 |
| 2124 | RRM2 | ARP46031_P050 | Lane, K. R. et al. Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One 8, e58456 (2013). 23520512 | 23520512 |
| 2125 | RRP1 | ARP45812_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2126 | RTN3 | OABB01421 | Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. Dev Neurosci. 40, 325-336 (2018). 30399610 | 30399610 |
| 2127 | RTN4 | ARP46812_P050 | Beetz, C. et al. A spastic paraplegia mouse model reveals REEP1-dependent ER shaping. J. Clin. Invest. 123, 4273-82 (2013). 24051375 | 24051375 |
| 2128 | RTN4 | ARP46812_P050 | Reticulon 4a promotes exocytosis in mammalian cells. Mol Biol Cell. 30, 2349-2357 (2019). 31318320 | 31318320 |
| 2129 | RuBisCo | OKGD00011 | Can improved canopy light transmission ameliorate loss of photosynthetic efficiency in the shade? An investigation of natural variation in Sorghum bicolor. J Exp Bot 2021 13 72 4965-4980 33914063 | 33914063 |
| 2130 | RUNX2 | ARP36678_T100 | Schuchardt, M. et al. Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification. Kidney Int. 81, 256-65 (2012). 21956191 | 21956191 |
| 2131 | RUNX2 | ARP38452_P050 | Lee, H.-K. et al. The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. J. Cell. Biochem. 111, 755-67 (2010). 20665536 | 20665536 |
| 2132 | RUNX2 | ARP38452_P050 | Li, W. et al. Construction of adipose scaffold for bone repair with gene engineering bone cells. Exp. Biol. Med. (Maywood). 238, 1350-4 (2013). 24131542 | 24131542 |
| 2133 | RUNX2 | ARP38453_P050 | Synergistic effects of overexpression of BMP‑2 and TGF‑b3 on osteogenic differentiation of bone marrow mesenchymal stem cells. Mol Med Rep. 14, 5514-5520 (2016). 27878265 | 27878265 |
| 2134 | RUNX2 | OALA04014 | RUNX2 controls human IPO8 basal transcription in Saos-2 cells. Mol Med Rep. 14, 1418-24 (2016). 27277970 | 27277970 |
| 2135 | RUVBL2 | ARP32379_P050 | Barthéléry, M., Jaishankar, A., Salli, U. & Vrana, K. E. Reptin52 expression during in vitro neural differentiation of human embryonic stem cells. Neurosci. Lett. 452, 47-51 (2009). 19444951 | 19444951 |
| 2136 | S100A7 | OKCD07935 | Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. Nat Commun 2022 1 13 1928 35396513 | 35396513 |
| 2137 | S1PR5 | ARP42661_T100 | Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. J. Dermatol. Sci. 82, 9-17 (2016). 26803226 | 26803226 |
| 2138 | SAA1 | ARP48081_P050 | Zeng, J., Du, S., Zhou, J. & Huang, K. Role of SelS in lipopolysaccharide-induced inflammatory response in hepatoma HepG2 cells. Arch. Biochem. Biophys. 478, 1-6 (2008). 18675776 | 18675776 |
| 2139 | SAA1 | OKEH04394 | Wicker, E et al. Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury. Biomed Res Int. 2019; 2019: 5967816. 31119176 | 31119176 |
| 2140 | SAC | ARP47447_P050 | Corredor, R. G. et al. Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth. J. Neurosci. 32, 7734-44 (2012). 22649251 | 22649251 |
| 2141 | Salbutamol-HRP | OORB00127 | Suherman, Morita, K. & Kawaguchi, T. Highly selective and sensitive detection of beta-agonists using a surface plasmon resonance sensor based on an alkanethiol monolayer functionalized on a Au surface. Biosens. Bioelectron. (2014). doi:10.1016/j.bios.2014.08.055 25192871 | 25192871 |
| 2142 | SARDH | ARP42344_T100 | Khan, A. P. et al. The role of sarcosine metabolism in prostate cancer progression. Neoplasia 15, 491-501 (2013). 23633921 | 23633921 |
| 2143 | SART3 | ARP39128_T100 | Cellular Immune Responses for Squamous Cell Carcinoma Antigen Recognized by T Cells 3 in Patients with Hepatocellular Carcinoma. PLoS ONE. 12, e0170291 (2017). 28114424 | 28114424 |
| 2144 | SBDS | ARP45719_T100 | Sezgin, G. et al. Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS. Pediatr. Blood Cancer 60, 281-6 (2013). 22997148 | 22997148 |
| 2145 | SCARB1 | ARP63158_P050 | Fu, Y. et al. ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis. Cell Metab. 18, 225-38 (2013). 23931754 | 23931754 |
| 2146 | SCN3B | ARP37699_P050 | Hu, D. et al. A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype. Circ. Cardiovasc. Genet. 2, 270-8 (2009). 20031595 | 20031595 |
| 2147 | SCN3B | ARP37699_P050 | Ho, C., Zhao, J., Malinowski, S., Chahine, M. & O’Leary, M. E. Differential expression of sodium channel beta subunits in dorsal root ganglion sensory neurons. J. Biol. Chem. 287, 15044-53 (2012). 22408255 | 22408255 |
| 2148 | SCN3B | ARP37699_P050 | Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells. Acta Physiol (Oxf). 213, 882-92 (2015). 25627423 | 25627423 |
| 2149 | SCN5 | ARP34934_P050 | Matsushita, N. et al. Nicorandil improves electrical remodelling, leading to the prevention of electrically induced ventricular tachyarrhythmia in a mouse model of desmin-related cardiomyopathy. Clin. Exp. Pharmacol. Physiol. 41, 89-97 (2014). 24117876 | 24117876 |
| 2150 | SCN5A | ARP35542_P050 | Colussi, C. et al. The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice. Cardiovasc. Res. 87, 73-82 (2010). 20164117 | 20164117 |
| 2151 | SCN5A | ARP35542_P050 | House, C. D. et al. Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion. Cancer Res. 70, 6957-67 (2010). 20651255 | 20651255 |
| 2152 | SCN5A | ARP35542_P050 | Costa, A. R. et al. Optical mapping of cryoinjured rat myocardium grafted with mesenchymal stem cells. Am. J. Physiol. Heart Circ. Physiol. 302, H270-7 (2012). 22037193 | 22037193 |
| 2153 | SCN5A | ARP35542_P050 | Askar, S. F. A. et al. Similar arrhythmicity in hypertrophic and fibrotic cardiac cultures caused by distinct substrate-specific mechanisms. Cardiovasc. Res. 97, 171-81 (2013). 22977008 | 22977008 |
| 2154 | SCUBE1 | OKEH01867 | SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function: Implications for Diagnostic Marker Development in Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 5, 1073-1092 (2020). 33294740 | 33294740 |
| 2155 | SCUBE1 | OKEH05018 | SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function: Implications for Diagnostic Marker Development in Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 5, 1073-1092 (2020). 33294740 | 33294740 |
| 2156 | SCUBE1 | OKEI00879 | SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function: Implications for Diagnostic Marker Development in Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 5, 1073-1092 (2020). 33294740 | 33294740 |
| 2157 | SCXA | OAAB00449 | The effects of scaffold architecture and fibrin gel addition on tendon cell phenotype. J Mater Sci Mater Med. 26, 5349 (2015) 25578703 | 25578703 |
| 2158 | SDHB | ARP47981_P050 | Qattan, A. T., Radulovic, M., Crawford, M. & Godovac-Zimmermann, J. Spatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cells. J. Proteome Res. 11, 6080-101 (2012). 23051583 | 23051583 |
| 2159 | SEC63 | ARP46839_T100 | Receptor-mediated Drp1 oligomerization on endoplasmic reticulum. J Cell Biol. 216, 4123-4139 (2017). 29158231 | 29158231 |
| 2160 | SECTM1 | ARP45408_P050 | Bade-Döding, C. et al. Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7. Biochim. Biophys. Acta 1840, 1004-13 (2014). 24211252 | 24211252 |
| 2161 | SelS | ARP48082_P050 | Zeng, J., Du, S., Zhou, J. & Huang, K. Role of SelS in lipopolysaccharide-induced inflammatory response in hepatoma HepG2 cells. Arch. Biochem. Biophys. 478, 1-6 (2008). 18675776 | 18675776 |
| 2162 | SELS | ARP48082_P050 | Du, S., Liu, H. & Huang, K. Influence of SelS gene silence on beta-Mercaptoethanol-mediated endoplasmic reticulum stress and cell apoptosis in HepG2 cells. Biochim. Biophys. Acta 1800, 511-7 (2010). 20114070 | 20114070 |
| 2163 | SEMA3A | OKEH01609 | Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism. Biochem Biophys Rep. 17, 132-138 (2019). 30623117 | 30623117 |
| 2164 | SEMA4B | ARP49485_P050 | Combined shRNA over CRISPR/cas9 as a methodology to detect off-target effects and a potential compensatory mechanism. Sci Rep. 8, 93 (2018). 29311693 | 29311693 |
| 2165 | SEROTONIN | OKEH02558 | MC4R Signaling in Dorsal Raphe Nucleus Controls Feeding, Anxiety, and Depression. Cell Rep. 33, 108267 (2020). 33053350 | 33053350 |
| 2166 | SERPINA1 | ARP59239_P050 | Koh, K. H. et al. Differential gene expression profiles of metastases in paired primary and metastatic colorectal carcinomas. Oncology 75, 92-101 (2008). 18784436 | 18784436 |
| 2167 | SERPINA1 | ARP59239_P050 | Kam, S. Y. et al. Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: implications for biomarker studies. J. Proteome Res. 10, 4535-46 (2011). 21842849 | 21842849 |
| 2168 | SERPINA1 | ARP59239_P050 | Novel blood test for early biomarkers of preeclampsia and Alzheimer's disease. Sci Rep. 11, 15934 (2021) 34354200 | 34354200 |
| 2169 | SERPINA1 | OABB01837 | Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology. Cell Transplant. 25, 2221-2243 (2016). 27512979 | 27512979 |
| 2170 | SERPINA1 | OKIA00048 | Case study on human a1-antitrypsin: Recombinant protein titers obtained by commercial ELISA kits are inaccurate. Biotechnol J. 11, 1648-1656 (2016). 27731958 | 27731958 |
| 2171 | SERPINA3 | ARP51880_P050 | Latouche, C. et al. Molecular signature of mineralocorticoid receptor signaling in cardiomyocytes: from cultured cells to mouse heart. Endocrinology 151, 4467-76 (2010). 20591974 | 20591974 |
| 2172 | SERPINA3N | OKEH03592 | Linagliptin, A Xanthine-Based Dipeptidyl Peptidase-4 Inhibitor, Ameliorates Experimental Autoimmune Myocarditis. JACC Basic Transl Sci 2021 6 6 527-542 34222724 | 34222724 |
| 2173 | SERPINB1 | ARP52417_P050 | Pro-inflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis. BMC Vet Res. 15, 225 (2019). 31269952 | 31269952 |
| 2174 | SERPINB4 | ARP42085_P050 | Harden, C. J. et al. Evaluation of the salivary proteome as a surrogate tissue for systems biology approaches to understanding appetite. J. Proteomics 75, 2916-23 (2012). 22200674 | 22200674 |
| 2175 | SERPINB4 | ARP42085_P050 | Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. Cell Res. 28, 625-643 (2018). 29808012 | 29808012 |
| 2176 | SERPINB5 | ARP42055_T100 | Mardin, W. A. et al. SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma. BMC Cancer 10, 549 (2010). 20939879 | 20939879 |
| 2177 | SERPINB5 | ARP42055_T100 | Hrabakova, R. et al. Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. J. Proteome Res. 12, 455-69 (2013). 23151231 | 23151231 |
| 2178 | SERPINB5 | ARP42055_T100 | SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis. Pancreas. 45, 743-7 (2016). 26646275 | 26646275 |
| 2179 | SERPING1 | OPCA00220 | Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation.Int J Biol Sci5168-51841813August2022 | 35982894 |
| 2180 | SERPINH1 | OACA06643 | Baseline Clinical and Biomarker Characteristics of Biobank Innovations for Chronic Cerebrovascular Disease With Alzheimer's Disease Study: BICWALZS. Psychiatry Investig. (2022). 35042283 | 35042283 |
| 2181 | SERTAD1 | ARP34309_T100 | Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway. Mol Cells. (2022). 35014620 | 35014620 |
| 2182 | SetD2 | ARP47617_T100 | Barrand, S., Andersen, I. S. & Collas, P. Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes. Biochem. Biophys. Res. Commun. 401, 611-7 (2010). 20920475 | 20920475 |
| 2183 | SETD2 | ARP47617_T100 | Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nat Genet. 46, 287-93 (2014). 24509477 | 24509477 |
| 2184 | SETD2 | OAEB00589 | The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain. Nat Commun. 12, 1443 (2021) 33664260 | 33664260 |
| 2185 | SETD2 | OAEB00589 | Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun. 12, 6452 (2021). 34750379 | 34750379 |
| 2186 | SF1 | ARP41214_T100 | Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 19, 704-21 (2014). 25145264 | 25145264 |
| 2187 | SF3A1 | ARP40616_P050 | Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1. PLoS One. 10, e0123121 (2015). 25874565 | 25874565 |
| 2188 | SF3A2 | ARP73890_P050 | PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression. Cancer Res. 78, 3190-3206 (2018). 29700004 | 29700004 |
| 2189 | sFRP1 | AVARP09053_T100 | Qiu, Y. et al. Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma. Anat. Rec. (Hoboken). 293, 2020-6 (2010). 21046672 | 21046672 |
| 2190 | SFRS1 | ARP40691_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 2191 | SFRS10 | ARP40528_T100 | Fu, K. et al. Tra2beta protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon. J. Biol. Chem. 287, 16575-85 (2012). 22437831 | 22437831 |
| 2192 | SFRS6 | ARP40632_P050 | Gautrey, H. L. & Tyson-Capper, A. J. Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells. PLoS One 7, e51497 (2012). 23284704 | 23284704 |
| 2193 | SFSWAP | ARP40524_P050 | Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins. Nucleic Acids Res. 43, 10456-73 (2015). 26420826 | 26420826 |
| 2194 | SFTPA1 | OKCD02903 | Change of surfactant protein D and A after renal ischemia reperfusion injury. PLoS One. 14, e0227097 (2019). 31877195 | 31877195 |
| 2195 | SGMS1 | ARP55476_P050 | Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator. EBioMedicine. 7, 121-34 (2016). 27322466 | 27322466 |
| 2196 | SGPP2 | ARP45734_T100 | Rajkumar Vutukuri, et al. Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption. 172-185 (2018). 29023711 | 29023711 |
| 2197 | SGTA | ARP64527_P050 | Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice. Sci Rep. 6, 28950 (2016). 27358191 | 27358191 |
| 2198 | SH3BGR | ARP45764_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2199 | SHH | ARP44235_P050 | Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model.Cancers (Basel)NULL1417August2022 | 36077751 |
| 2200 | SIGLEC1 | OASA04956 | Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner. J Biol Chem. 290, 27345-59 (2015). 26370074 | 26370074 |
| 2201 | SIK1 | ARP45917_P050 | The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte. Mol. Cell. Endocrinol. 414, 156-67 (2015). 26210066 | 26210066 |
| 2202 | SIM1 | ARP33296_P050 | Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 413, 86-103 (2016) 26187199 | 26187199 |
| 2203 | SIM2 | ARP38551_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2204 | SIP1 | ARP39141_P050 | Regulation of trunk neural crest delamination by dEF1 and Sip1 in the chicken embryo. Dev. Growth Differ. 58, 205-14 (2016). 26691438 | 26691438 |
| 2205 | SIRPA | AVARP00011_P050 | Prion pathogenesis is unaltered in the absence of SIRPa-mediated "don't-eat-me" signaling. PLoS One. 12, e0177876 (2017). 28545141 | 28545141 |
| 2206 | SIRT1 | ARP32386_P050 | Cueno, M. E., Imai, K., Tamura, M. & Ochiai, K. Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease. Cell Stress Chaperones. doi:10.1007/s12192-013-0462-7 (2013). 24052229 | 24052229 |
| 2207 | SIRT1 | ARP32386_P050 | Hsu, C.-Y. & Chuang, Y.-L. Changes in Energy-Regulated Molecules in the Trophocytes and Fat Cells of Young and Old Worker Honeybees (Apis mellifera). J. Gerontol. A. Biol. Sci. Med. Sci. (2013). doi:10.1093/gerona/glt163 24149426 | 24149426 |
| 2208 | SirT1 | ARP32386_P050 | Hsu, C.-Y. & Hu, T.-H. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15, 389-400 (2014). 24973265 | 24973265 |
| 2209 | SIRT1 | ARP32386_P050 | Localization of sirtuins (SIRT1-7) in the aged mouse inner ear. Acta Otolaryngol. 136, 120-31 (2016). 26472659 | 26472659 |
| 2210 | SIRT1 | ARP32386_T100 | Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell. 8, 726-37 (2009). 19780720 | 19780720 |
| 2211 | SIRT1 | ARP32386_T100 | Late-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway. Rejuvenation Res. 17, 507-17 (2014). 25298234 | 25298234 |
| 2212 | SIRT1 | ARP32386_T100 | Dietary saturated fatty acids reduce hepatic lipid accumulation but induce fibrotic change in alcohol-fed rats. Hepatobiliary Surg Nutr. 4, 172-83 (2015). 26151057 | 26151057 |
| 2213 | SIRT1 | OKEH01724 | Evaluation of BCL6 and SIRT1 as Non-Invasive Diagnostic Markers of Endometriosis. Curr Issues Mol Biol 2021 3 43 1350-1360 34698105 | 34698105 |
| 2214 | SIRT2 | ARP32384_P050 | Benavente, C. A., Schnell, S. A. & Jacobson, E. L. Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin. PLoS One 7, e42276 (2012). 22860104 | 22860104 |
| 2215 | SIRT3 | ARP32389_P050 | Lanza, I. R. et al. Endurance exercise as a countermeasure for aging. Diabetes 57, 2933-42 (2008). 18716044 | 18716044 |
| 2216 | SIRT3 | ARP32389_P050 | Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). 22087287 | 22087287 |
| 2217 | SIRT3 | ARP32389_P050 | Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas. Sci Adv. 2, e1601132 (2016). 27847869 | 27847869 |
| 2218 | SIRT5 | ARP40125_T100 | Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner. Cell Death Differ. 23, 29-40 (2016). 26001219 | 26001219 |
| 2219 | SIRT5 | ARP40125_T100 | Impact of acute kidney injury on renal allograft survival. Ren Fail. 39, 40-44 (2017). 27776444 | 27776444 |
| 2220 | SIRT6 | ARP32408_P050 | Gazin, C., Wajapeyee, N., Gobeil, S., Virbasius, C.-M. & Green, M. R. An elaborate pathway required for Ras-mediated epigenetic silencing. Nature 449, 1073-7 (2007). 17960246 | 17960246 |
| 2221 | SIRT6 | ARP32408_P050 | Wajapeyee, N., Malonia, S. K., Palakurthy, R. K. & Green, M. R. Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev. 27, 2221-6 (2013). 24105743 | 24105743 |
| 2222 | SIRT6 | OKCD02892 | Dichotomous responses to chronic fetal hypoxia lead to a predetermined aging phenotype. Mol Cell Proteomics. 100190 (2021). 34958949 | 34958949 |
| 2223 | SIX1 | ARP32375_P050 | Lee, S. H. et al. Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. J. Mol. Cell. Cardiol. 52, 718-26 (2012). 22197309 | 22197309 |
| 2224 | SKOR2 | OAAB18965 | Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors. Development. 144, 3686-3697 (2017). 28893945 | 28893945 |
| 2225 | SKOR2 | OAAB18965 | Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis. Cell Rep. 30, 3616-3624.e4 (2020). 32187534 | 32187534 |
| 2226 | SLC10A1 | ARP42097_P050 | Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes. Stem Cell Reports. 7, 543-556 (2016). 27569060 | 27569060 |
| 2227 | SLC10A2 | OAEB00210 | Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas. Mol Metab. 11, 84-95 (2018). 29656109 | 29656109 |
| 2228 | SLC12A1 | OABB01331 | "Reversed polarization" of Na/K-ATPase-a sign of inverted transport in the human endolymphatic sac: a super-resolution structured illumination microscopy (SR-SIM) study. Cell Tissue Res. 379, 445-457 (2020). 31713726 | 31713726 |
| 2229 | SLC12A2 | ARP43805_T100 | Chen, N. et al. Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC. Proteomics 8, 5108-18 (2008). 19016532 | 19016532 |
| 2230 | SLC12A2 | OABB01332 | Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter. Am J Physiol Cell Physiol. 317, C843-C856 (2019). 31365295 | 31365295 |
| 2231 | SLC12A2 | ARP43805_T100 | Jansen, L. A., Peugh, L. D., Roden, W. H. & Ojemann, J. G. Impaired maturation of cortical GABA(A) receptor expression in pediatric epilepsy. Epilepsia 51, 1456-67 (2010). 20132297 | 20132297 |
| 2232 | SLC12A5 | OASE00240 | Pharmaco-resistant Neonatal Seizures: Critical Mechanistic Insights from a Chemoconvulsant Model. Dev Neurobiol. 78, 1117-1130 (2018). 30136373 | 30136373 |
| 2233 | SLC12A5 | OASE00240 | TrkB agonists prevent postischemic emergence of refractory neonatal seizures in mice. JCI Insight. 5, NULL (2020). 32427585 | 32427585 |
| 2234 | SLC12A8 | ARP44039_P050 | Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 1, 47-57 (2019). 31131364 | 31131364 |
| 2235 | SLC13A3 | ARP41438_T100 | Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell. 22, 355-368.e13 (2018). 29478844 | 29478844 |
| 2236 | SLC19A1 | ARP44167_T100 | Marchi, E. et al. Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies. Clin. Cancer Res. 16, 3648-58 (2010). 20501616 | 20501616 |
| 2237 | SLC19A1 | ARP44167_T100 | Halwachs, S., Lakoma, C., Schäfer, I., Seibel, P. & Honscha, W. The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier. Mol. Pharmacol. 80, 621-9 (2011). 21737571 | 21737571 |
| 2238 | SLC1A4 | OAAN01042 | Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation.Am J Reprod Immunole13115816June2019 | 30924965 |
| 2239 | SLC1A5 | ARP42247_T100 | Zhu, Y. et al. L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells. Amino Acids (2014). doi:10.1007/s00726-014-1785-0 24997162 | 24997162 |
| 2240 | SLC1A5 | ARP42247_T100 | Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. Nature. 532, 389-93 (2016). 27064903 | 27064903 |
| 2241 | SLC1A5 | ARP42247_T100 | Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine. PLoS ONE. 11, e0162475 (2016). 27611307 | 27611307 |
| 2242 | SLC22A1 | ARP41516_T100 | Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res. 359, 465-477 (2015). 25418136 | 25418136 |
| 2243 | SLC22A1 | ARP41640_T100 | Salomon, J. J. et al. The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier. Mol. Pharm. (2014). doi:10.1021/mp4006536 24524365 | 24524365 |
| 2244 | SLC22A17 | ARP43966_P050 | The level of nitric oxide regulates lipocalin-2 expression under inflammatory condition in RINm5F beta-cells. Biochem. Biophys. Res. Commun. 476, 7-14 (2016). 27233602 | 27233602 |
| 2245 | SLC22A17 | OAEB00639 | Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares. J. Reprod. Dev. (2016). 27980236 | 27980236 |
| 2246 | SLC22A4 | OAAB03385 | Salomon, J. J. et al. The Cell Line NCl-H441 Is a Useful in Vitro Model for Transport Studies of Human Distal Lung Epithelial Barrier. Mol. Pharm. (2014). doi:10.1021/mp4006535 24524365 | 24524365 |
| 2247 | SLC22A5 | ARP63404_P050 | Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans. Am J Physiol Gastrointest Liver Physiol. 307, G673-88 (2014). 24970780 | 24970780 |
| 2248 | SLC23A1 | OAAB09000 | Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples. Cell Physiol Biochem. 55, 553-568 (2021). 34599650 | 34599650 |
| 2249 | SLC25A46 | ARP44094_T100 | Loss of SLC25A46 causes neurodegeneration by affecting mitochondrial dynamics and energy production in mice. Hum Mol Genet. 26, 3776-3791 (2017). 28934388 | 28934388 |
| 2250 | SLC25A5 | OAAB08798 | Park, J.-I. et al. B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria. Mol. Cell. Endocrinol. 367, 31-40 (2013). 23267836 | 23267836 |
| 2251 | SLC26A4 | ARP41739_P050 | Urinary Extracellular Vesicles for Renal Tubular Transporters Expression in Patients With Gitelman Syndrome. Front Med (Lausanne). 8, 679171 (2021) 34179047 | 34179047 |
| 2252 | SLC26A5 | OAEB00391 | Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs. Mol Ther. 26, 1313-1326 (2018). 29680697 | 29680697 |
| 2253 | SLC26A6 | OAEB02669 | Fecal transplant modifies urine chemistry risk factors for urinary stone disease. Physiol Rep. 7, e14012 (2019). 30789675 | 30789675 |
| 2254 | SLC27A5 | ARP41592_P050 | Aleksunes, L. M., Yeager, R. L., Wen, X., Cui, J. Y. & Klaassen, C. D. Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy. Toxicol. Sci. 130, 257-68 (2012). 22903823 | 22903823 |
| 2255 | SLC27A6 | ARP43781_P050 | Gaccioli, F. et al. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2 alpha signaling and increases fetal growth in rats. Biol. Reprod. 89, 96 (2013). 24006279 | 24006279 |
| 2256 | SLC29A2 | ARP43822_T100 | Okuda, H., Higashi, Y., Nishida, K., Fujimoto, S. & Nagasawa, K. Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes. Glia 58, 1757-65 (2010). 20645413 | 20645413 |
| 2257 | SLC2A2 | ARP41706_P050 | Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes. PLoS One. 12, e0176650 (2017). 28459862 | 28459862 |
| 2258 | SLC2A2 | ARP41706_P050 | Maternal Heat Stress Alters Expression of Genes Associated with Nutrient Transport Activity and Metabolism in Female Placentae from Mid-Gestating Pigs. Int J Mol Sci. 22 (2021). 33923747 | 33923747 |
| 2259 | SLC2A9 | ARP43757_P050 | Gaccioli, F. et al. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2 alpha signaling and increases fetal growth in rats. Biol. Reprod. 89, 96 (2013). 24006279 | 24006279 |
| 2260 | SLC30A1 | ARP44019_P050 | Bresson, C. et al. Cobalt chloride speciation, mechanisms of cytotoxicity on human pulmonary cells, and synergistic toxicity with zinc. Metallomics 5, 133-43 (2013). 23505636 | 23505636 |
| 2261 | SLC31A1 | ARP43824_P050 | Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story. World J Biol Psychiatry. 21, 13-28 (2020). 30230404 | 30230404 |
| 2262 | SLC34A3 | ARP32173_P050 | Starke, S., Cox, C., Südekum, K.-H. & Huber, K. Species-specific responses of N homeostasis and electrolyte handling to low N intake: a comparative physiological approach in a monogastric and a ruminant species. J. Comp. Physiol. B. 184, 137-47 (2014). 24129944 | 24129944 |
| 2263 | SLC34A3 | ARP33751_P050 | Impact of Pals1 on Expression and Localization of Transporters Belonging to the Solute Carrier Family. Front Mol Biosci 2022 NULL 9 792829 35252349 | 35252349 |
| 2264 | SLC36A4 | ARP44114_P050 | The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. Aging Cell. 16, 349-359 (2017). 28083894 | 28083894 |
| 2265 | SLC38A2 | ARP38765_T100 | Intermittent Bolus Compared With Continuous Feeding Enhances Insulin and Amino Acid Signaling to Translation Initiation in Skeletal Muscle of Neonatal Pigs. J Nutr 2021 9 151 2636-2645 34159368 | 34159368 |
| 2266 | SLC38A9 | ARP53259_P050 | Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs. Am J Physiol Endocrinol Metab. 2016 Apr 15; 310(8): E699-E713. 26884386 | 26884386 |
| 2267 | SLC39A6 | ARP43931_T100 | Trokovic, N. et al. Exosomal secretion of death bullets: a new way of apoptotic escape? Am. J. Physiol. Endocrinol. Metab. 303, E1015-24 (2012). 22912365 | 22912365 |
| 2268 | SLC3A2 | OASA02585 | Quantitative Algorithm-Based Paired Imaging Measurement for Antibody-Triggered Endocytosis in Cultured Cells. SLAS Discov. 23, 832-841 (2018). 29505735 | 29505735 |
| 2269 | SLC3A2 | OAEB02736 | Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells. Front Oncol 2022 NULL 12 841054 35223522 | 35223522 |
| 2270 | SLC44A2 | ARP44009_P050 | The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function. Nat Commun. 11, 3479 (2020). 32661250 | 32661250 |
| 2271 | SLC44A3 | ARP44120_P050 | Kojima, S., Sher-Chen, E. L. & Green, C. B. Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression. Genes Dev. 26, 2724-36 (2012). 23249735 | 23249735 |
| 2272 | SLC47A2 | ARP45222_P050 | Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier. Drug Metab Dispos 2022 6 50 770-780 35307651 | 35307651 |
| 2273 | SLC5A5 | ARP43752_P050 | Liu, F. et al. Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex. PLoS One 7, e38589 (2012). 22719903 | 22719903 |
| 2274 | SLC5A8 | ARP44110_P050 | Zhang, Y. et al. Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells. Int. J. Biochem. Cell Biol. 42, 1964-72 (2010). 20732443 | 20732443 |
| 2275 | SLC5A8 | ARP44110_P050 | Babu, E. et al. Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. Oncogene 30, 4026-37 (2011). 21499304 | 21499304 |
| 2276 | SLC5A8 | ARP44110_P050 | Elangovan, S. et al. Molecular mechanism of SLC5A8 inactivation in breast cancer. Mol. Cell. Biol. 33, 3920-35 (2013). 23918800 | 23918800 |
| 2277 | SLC5A8 | OABF01657 | Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats. Acta Physiol (Oxf). 226, e13256 (2019). 30656835 | 30656835 |
| 2278 | SLC6A14 | ARP43925_P050 | González, I. M. et al. Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. Dev. Biol. 361, 286-300 (2012). 22056783 | 22056783 |
| 2279 | SLC6A14 | ARP43925_P050 | Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer. Br. J. Pharmacol. (2016). 27747870 | 27747870 |
| 2280 | SLC6A2 | ARP41893_P050 | Bayles, R. et al. Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome. Arterioscler. Thromb. Vasc. Biol. 32, 1910-6 (2012). 22723437 | 22723437 |
| 2281 | Slc6a9 | ARP42330_P050 | Poly(I:C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation.Am J Reprod Immunole13115816June2019 | 30924965 |
| 2282 | SLC7A2 | ARP43766_P050 | Kohlhaas, C. F. et al. Insulin rapidly stimulates L-arginine transport in human aortic endothelial cells via Akt. Biochem. Biophys. Res. Commun. 412, 747-51 (2011). 21871446 | 21871446 |
| 2283 | Slc7a3 | OAAN02059 | FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors. Mol Psychiatry 2021 11 26 6845-6867 33863995 | 33863995 |
| 2284 | SLC7A8 | ARP43930_T100 | Increased SLC7A8 expression mediates L-DOPA uptake by renal tubular epithelial cells. Mol Med Rep. 16, 887-893 (2017). 28560461 | 28560461 |
| 2285 | SLC8A3 | ARP44074_P050 | Heise, N. et al. Effect of dexamethasone on Na+/Ca2+ exchanger in dendritic cells. Am. J. Physiol. Cell Physiol. 300, C1306-13 (2011). 21307349 | 21307349 |
| 2286 | SLC8B1 | ARP44042_P050 | Na+ controls hypoxic signalling by the mitochondrial respiratory chain. Nature. 586, 287-291 (2020) 32728214 | 32728214 |
| 2287 | SLC9A3 | ARP43870_P050 | Impairment of electroneutral Na+ transport and associated downregulation of NHE3 contributes to the development of diarrhea following in vivo challenge with Brachyspira spp. Am J Physiol Gastrointest Liver Physiol. 318, G288-G297 (2020). 31760765 | 31760765 |
| 2288 | SLCO1B3 | OAAB14502 | Interindividual Diversity in Expression of Organic Anion Uptake Transporters in Normal and Cirrhotic Human Liver. Hepatol Commun. 4, 739-752 (2020). 32363323 | 32363323 |
| 2289 | SLPI | OAPB00538 | MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands. PLoS One. 9, e113333 (2014). 25415419 | 25415419 |
| 2290 | SMAD3 | OAAB06596 | Uchiyama, Y. et al. SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc. J. Bone Miner. Res. 23, 1619-28 (2008). 18466073 | 18466073 |
| 2291 | SMAD7 | ARP32008_P050 | Higher Anti-Liver Fibrosis Effect of Cordyceps militaris-Fermented Product Cultured with Deep Ocean Water via Inhibiting Proinflammatory Factors and Fibrosis-Related Factors Expressions. Mar Drugs. 15, (2017). 28594374 | 28594374 |
| 2292 | SMN1 | ARP40209_P050 | Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses. PLoS One. 6, e24269 (2011). 21904622 | 21904622 |
| 2293 | SMPDL3B | ARP33875_P050 | Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages. J Biol Chem. 289, 32895-913 (2014). 25288789 | 25288789 |
| 2294 | SNAI1 | ARP33314_P050 | Wang, H. et al. PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition. Cancer Res. 67, 2922-6 (2007). 17409395 | 17409395 |
| 2295 | SNAI1 | ARP33314_P050 | Surati, M. et al. Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. J. Clin. Bioinforma. 1, 1-11 (2011). 21603121 | 21603121 |
| 2296 | SNAI1 | ARP33314_P050 | Cooper, C. D. O. et al. Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. PLoS One 6, e23916 (2011). 21914172 | 21914172 |
| 2297 | SNAT2 | ARP33059_P050 | Suryawan, A., Nguyen, H. V, Almonaci, R. D. & Davis, T. A. Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated. Amino Acids 45, 523-30 (2013). 22643846 | 22643846 |
| 2298 | SNAT2 | ARP33059_P050 | Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia. Pediatr. Res. 80, 448-51 (2016). 27064245 | 27064245 |
| 2299 | SNRP70 | ARP40275_P050 | Wang, E. & Cambi, F. Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J. Biol. Chem. 284, 11194-204 (2009). 19244236 | 19244236 |
| 2300 | SNRP70 | ARP40439_P050 | Franklin, S. et al. Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy. Mol. Cell. Proteomics 10, M110.000703 (2011). 20807835 | 20807835 |
| 2301 | SNRP70 | ARP40439_P050 | Serini, S. et al. DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and beta-catenin nuclear translocation. Carcinogenesis 33, 164-73 (2012). 22045024 | 22045024 |
| 2302 | SNRP70 | ARP40439_P050 | Franklin, S. et al. Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol. Cell. Proteomics 11, M111.014258 (2012). 22270000 | 22270000 |
| 2303 | SNRPA | ARP40531_P050 | Wang, E. & Cambi, F. Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs. J. Biol. Chem. 284, 11194-204 (2009). 19244236 | 19244236 |
| 2304 | SOCS2 | OPSA10707 | The Role of GLP1 in Rat Steatotic and Non-Steatotic Liver Transplantation from Cardiocirculatory Death Donors. Cells 2019 12 8 NULL 31835410 | 31835410 |
| 2305 | SOD1 | OASE00355 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
| 2306 | SOD2 | OASE00357 | Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis. Int J Mol Med. 42, 789-798 (2018). 29717771 | 29717771 |
| 2307 | SOD2 | OASE00357 | PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells. Exp Ther Med. 19, 849-860 (2020). 32010245 | 32010245 |
| 2308 | SOD3 | OKCD01107 | Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health. Cell Metab 2021 5 33 939-956.e8 33770509 | 33770509 |
| 2309 | SOX10 | ARP33326_P050 | Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 35, 352-65 (2015). 25568127 | 25568127 |
| 2310 | SOX10 | ARP33326_P050 | SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination. Sci Rep. 6, 17735 (2016). 26787558 | 26787558 |
| 2311 | SOX10 | ARP42065_P050 | Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity. PLoS One 2021 2 16 e0246989 33577554 | 33577554 |
| 2312 | SOX11 | ARP33327_P050 | Li, Y. et al. Sox11 modulates neocortical development by regulating the proliferation and neuronal differentiation of cortical intermediate precursors. Acta Biochim. Biophys. Sin. (Shanghai). 44, 660-8 (2012). 22687574 | 22687574 |
| 2313 | SOX11 | ARP33328_P050 | Shim, S., Kwan, K. Y., Li, M., Lefebvre, V. & Sestan, N. Cis-regulatory control of corticospinal system development and evolution. Nature 486, 74-9 (2012). 22678282 | 22678282 |
| 2314 | SOX11 | ARP38235_P050 | Cis-regulatory control of corticospinal system development and evolution. Nature. 486, 74-9 (2012). 22678282 | 22678282 |
| 2315 | SOX17 | ARP39552_P050 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
| 2316 | SOX17 | ARP58479_P050 | Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations. JCI Insight 2022 11 7 NULL 35511435 | 35511435 |
| 2317 | SOX18 | ARP33056_P050 | Duong, T. et al. Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Res. 72, 3105-14 (2012). 22523034 | 22523034 |
| 2318 | SOX18 | ARP33056_P050 | Deng, Y., Atri, D., Eichmann, A. & Simons, M. Endothelial ERK signaling controls lymphatic fate specification. J. Clin. Invest. 123, 1202-15 (2013). 23391722 | 23391722 |
| 2319 | Sox18 | ARP33056_P050 | Park, D.-Y. et al. Lymphatic regulator PROX1 determines Schlemm canal integrity and identity. J. Clin. Invest. 124, 3960-3974 (2014). 25061877 | 25061877 |
| 2320 | SOX2 | ARP31737_P050 | Perry, K. J., Thomas, A. G. & Henry, J. J. Expression of pluripotency factors in larval epithelia of the frog Xenopus: evidence for the presence of cornea epithelial stem cells. Dev. Biol. 374, 281-94 (2013). 23274420 | 23274420 |
| 2321 | SOX4 | ARP38234_P050 | STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4. Mol Cancer. 16, 136 (2017). 28810927 | 28810927 |
| 2322 | SOX5 | ARP33323_P050 | Martelli, M. L. et al. Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes. BMC Genomics 9, 254 (2008). 18510758 | 18510758 |
| 2323 | SOX5 | ARP33323_P050 | Tchougounova, E. et al. Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence. Oncogene 28, 1537-48 (2009). 19219070 | 19219070 |
| 2324 | SOX5 | ARP33323_P050 | Wright, D. et al. Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens. PLoS Genet. 5, e1000512 (2009). 19521496 | 19521496 |
| 2325 | SOX5 | ARP33323_P050 | Torii, M., Hashimoto-Torii, K., Levitt, P. & Rakic, P. Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature 461, 524-8 (2009). 19759535 | 19759535 |
| 2326 | SOX5 | ARP33323_P050 | Pytel, P. et al. Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development. Int. J. Surg. Pathol. 18, 449-57 (2010). 20034979 | 20034979 |
| 2327 | SOX5 | ARP33323_P050 | Kiselak, E. A. et al. Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5. J. Biol. Chem. 285, 30496-505 (2010). 20668334 | 20668334 |
| 2328 | SOX5 | ARP33323_P050 | Aza-Carmona, M. et al. SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer. Hum. Mol. Genet. 20, 1547-59 (2011). 21262861 | 21262861 |
| 2329 | SOX5 | ARP33323_P050 | Yu, J. et al. Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor. Clin. Cancer Res. 17, 1924-34 (2011). 21325289 | 21325289 |
| 2330 | SOX5 | ARP33323_P050 | Boije, H. et al. Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation. PLoS One 7, e50890 (2012). 23227218 | 23227218 |
| 2331 | SOX5 | ARP33323_P050 | Fernandes, A. M. et al. Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage. PLoS One 8, e62994 (2013). 23671648 | 23671648 |
| 2332 | Sox5 | ARP33323_P050 | Naveau, E. et al. Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls. PLoS One 9, e91903 (2014). 24642964 | 24642964 |
| 2333 | SOX5 | ARP33323_P050 | Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5. BMC Mol. Biol. 18, 2 (2017). 28137312 | 28137312 |
| 2334 | SOX5 | ARP33323_P050 | A Novel Method to Induce Cartilage Regeneration with Cubic Microcartilage.Cells Tissues Organs251-26020444687October2017 | 28972948 |
| 2335 | SOX9 | ARP37986_P050 | Tezak, B., I. Romero, S. Milton and J. Wyneken. Identifying Sex of Neonate Turtles with Temperature-dependent Sex Determination via Small Blood Samples. Sci Rep. 2020; 10: 5012. 32193464 | 32193464 |
| 2336 | Sox9 | OAAF00840 | Ferrand, N. et al. Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype. PLoS One 9, e87878 (2014). 24498388 | 24498388 |
| 2337 | SOX9 | OAAF00840 | Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). 24707296 | 24707296 |
| 2338 | SOXS9 | ARP37986_P050 | Lau, E.-L., Lee, M.-F. & Chang, C.-F. Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii. Biol. Reprod. 88, 150 (2013). 23616595 | 23616595 |
| 2339 | SPAG9 | OAAB04262 | Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer. Oncotarget. 7, 72845-72859 (2016). 27655714 | 27655714 |
| 2340 | SPARC | ARP63168_P050 | SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells. Int. J. Oncol. 49, 1394-406 (2016). 27498840 | 27498840 |
| 2341 | SPIB | ARP38242_P050 | Zhao, Y. et al. A functional MicroRNA-155 ortholog encoded by the oncogenic Marek’s disease virus. J. Virol. 83, 489-92 (2009). 18945769 | 18945769 |
| 2342 | SPIC | ARP32232_P050 | Zhu, X., Schweitzer, B. L., Romer, E. J., Sulentic, C. E. W. & DeKoter, R. P. Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling. Eur. J. Immunol. 38, 2587-99 (2008). 18792411 | 18792411 |
| 2343 | SPIRE1 | OAAB12896 | DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. Elife. 4, e07735 (2015). 26287480 | 26287480 |
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| 2345 | SPOCK3 | ARP44921_P050 | Lutter, S., Xie, S., Tatin, F. & Makinen, T. Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation. J. Cell Biol. 197, 837-49 (2012). 22665518 | 22665518 |
| 2346 | SPPL2b | ARP44989_P050 | Del Campo, M. et al. BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer’s disease. Neurobiol. Aging 35, 1596-604 (2014). 24524963 | 24524963 |
| 2347 | SRD5A2 | ARP44265_P050 | Bertin, J., Dury, A. Y., Ouellet, J., Pelletier, G. & Labrie, F. Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction. J. Sex. Med. 11, 1949-61 (2014). 24919541 | 24919541 |
| 2348 | SRF | OAAF00701 | Myc requires RhoA/SRF to reprogram glutamine metabolism. Small GTPases. 1-9 (2016). 27532209 | 27532209 |
| 2349 | SRP19 | ARP40456_T100 | Arana-Argáez, V. E. et al. Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells. J. Biol. Chem. 285, 32824-33 (2010). 20729213 | 20729213 |
| 2350 | SSX2 | ARP37719_P050 | Jung, V. et al. Yeast-based identification of prostate tumor antigens provides an effective vaccine platform. Anticancer Res. 30, 895-902 (2010). 20393012 | 20393012 |
| 2351 | STAC2 | ARP69675_P050 | Stac Proteins Suppress Ca2+-Dependent Inactivation of Neuronal l-type Ca2+ Channels. J Neurosci. 38, 9215-9227 (2018). 30201773 | 30201773 |
| 2352 | STAMBPL1 | ARP57453_P050 | Lavorgna, A. & Harhaj, E. W. An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation. J. Virol. 86, 3357-69 (2012). 22258247 | 22258247 |
| 2353 | STARD6 | ARP65716_P050 | STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis. Exp Biol Med (Maywood). 239, 430-5 (2014). 24595982 | 24595982 |
| 2354 | STAT1 | ARP33373_P050 | Deng, W. et al. Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription signaling pathway. Cytotherapy 13, 431-40 (2011). 21174489 | 21174489 |
| 2355 | STAT1 | ARP38933_P050 | Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 8, 10555-64 (2015). 26617765 | 26617765 |
| 2356 | STAT3 | ARP38253_P050 | Deng, W. et al. Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription signaling pathway. Cytotherapy 13, 431-40 (2011). 21174489 | 21174489 |
| 2357 | STAT3 | ARP38253_P050 | Vega, V. L. et al. Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. J. Mol. Med. (Berl). doi:10.1007/s00109-014-1201-y (2014). 25163764 | 25163764 |
| 2358 | STAT3 | ARP38253_P050 | Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis. Int J Clin Exp Pathol. 8, 10555-64 (2015). 26617765 | 26617765 |
| 2359 | STAT3 | AVARP09057_P050 | Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. Virology. 494, 1-14 (2016). 27061052 | 27061052 |
| 2360 | STATH | ARP42102_P050 | Silva-Boghossian, C. M. et al. Quantitative proteomic analysis of gingival crevicular fluid in different periodontal conditions. PLoS One 8, e75898 (2013). 24098404 | 24098404 |
| 2361 | Sulfonamides residues | OKAO00112 | Engineering of Organic Solvent-Tolerant Antibody to Sulfonamides by CDR Grafting for Analytical Purposes. Anal Chem. (2021). 33728902 | 33728902 |
| 2362 | SULT1A1 | ARP49134_P050 | Yalcin, E. B. et al. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metab. Dispos. 41, 1642-50 (2013). 23775849 | 23775849 |
| 2363 | SULT1E1 | ARP48669_P050 | Yalcin, E. B. et al. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metab. Dispos. 41, 1642-50 (2013). 23775849 | 23775849 |
| 2364 | SULT1E1 | ARP48669_P050 | Bisphenol A sulfonation is impaired in metabolic and liver disease. Toxicol. Appl. Pharmacol. 292, 75-84 (2016). 26712468 | 26712468 |
| 2365 | SULT2B1 | ARP48635_P050 | Segala, G. et al. 5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of tamoxifen in breast cancer cells. Biochem. Pharmacol. 86, 175-89 (2013). 23500540 | 23500540 |
| 2366 | SUV39H1 | ARP32470_T100 | Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes. 59, 2904-15 (2010). 20699419 | 20699419 |
| 2367 | SUV420H1 | ARP34567_P050 | Gatta, R. & Mantovani, R. NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations. Nucleic Acids Res. 36, 6592-607 (2008). 18940868 | 18940868 |
| 2368 | SUV420H1 | ARP34567_P050 | Murata, T. et al. Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J. Virol. 86, 4752-61 (2012). 22357272 | 22357272 |
| 2369 | SUZ12 | ARP39190_P050 | De Cegli, R. et al. Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation. Nucleic Acids Res. 41, 711-26 (2013). 23180766 | 23180766 |
| 2370 | SVCT1 | OAAB09000 | Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice. Free Radic. Biol. Med. 99, 451-462 (2016). 27567539 | 27567539 |
| 2371 | SYNCRIP | ARP40641_T100 | Ting, C.-H. et al. The spinal muscular atrophy disease protein SMN is linked to the Golgi network. PLoS One 7, e51826 (2012). 23284781 | 23284781 |
| 2372 | SYNCRIP | ARP40641_T100 | Groen, E. J. N. et al. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. Hum. Mol. Genet. 22, 3690-704 (2013). 23681068 | 23681068 |
| 2373 | SYNGR4 | OAPB01027 | Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models. Hum Mol Genet. 29, 2647-2661 (2020). 32686835 | 32686835 |
| 2374 | SYP | ARP45435_P050 | Stenkamp-Strahm, C. M., Kappmeyer, A. J., Schmalz, J. T., Gericke, M. & Balemba, O. High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes. Cell Tissue Res. 354, 381-94 (2013). 23881404 | 23881404 |
| 2375 | SYP | ARP45435_P050 | TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis. Elife. 10, NULL (2021) 34569930 | 34569930 |
| 2376 | SYP | OKCD02915 | Effects of HIV gp120 on Neuroinflammation in Immunodeficient vs. Immunocompetent States. J Neuroimmune Pharmacol 2021 2 16 437-453 32627098 | 32627098 |
| 2377 | SYT13 | OAAB02896 | Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer. Mol Ther Nucleic Acids. 22, 791-802 (2020). 33230476 | 33230476 |
| 2378 | SYT13 | OAAB02896 | Synaptotagmin 13 Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer. Curr Oncol. 28, 4080-4092 (2021). 34677264 | 34677264 |
| 2379 | SYT7 | OASE00272 | CREB Promotes Beta Cell Gene Expression by Targeting Its Coactivators to Tissue-Specific Enhancers. Mol Cell Biol. 39, (2019). 31182641 | 31182641 |
| 2380 | T3 | OKBA00023 | Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta Neuropathol. 132, 841-858 (2016). Acta Neuropathol. 132, 841-858 (2016). 27815632 | 27815632 |
| 2381 | T4 | OKBA00024 | Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta Neuropathol. 132, 841-858 (2016). Acta Neuropathol. 132, 841-858 (2016). 27815632 | 27815632 |
| 2382 | TAF11 | ARP32136_P050 | Anish, R., Hossain, M. B., Jacobson, R. H. & Takada, S. Characterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements. PLoS One 4, e5103 (2009). 19337366 | 19337366 |
| 2383 | TAF15 | ARP30111_T100 | Perez, K. J., Martínez, F. P., Cosme-Cruz, R., Perez-Crespo, N. M. & Tang, Q. A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replication. J. Virol. 87, 2639-47 (2013). 23255797 | 23255797 |
| 2384 | TAF15 | ARP30112_P050 | Ko, S. Y., Lengyel, E. & Naora, H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol. Cell. Endocrinol. 317, 112-9 (2010). 20048082 | 20048082 |
| 2385 | TAFIa | ARP37302_P050 | Machida, M. et al. Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle. J. Cell. Physiol. 227, 1569-76 (2012). 21678406 | 21678406 |
| 2386 | Tal1 | ARP31428_P050 | Hosur, V. et al. Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice. PLoS One 8, e53426 (2013). 23301070 | 23301070 |
| 2387 | Tal1 | P100630_T100 | Akgül, B. et al. Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis. PLoS One 5, e15358 (2010). 21206920 | 21206920 |
| 2388 | TAL2 | ARP38618_P050 | Courtial, N. et al. The T-cell oncogene Tal2 Is a Target of PU.1 and upregulated during osteoclastogenesis. PLoS One 8, e76637 (2013). 24086757 | 24086757 |
| 2389 | TARDBP | ARP35837_P050 | LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Mol Cell. 48, 195-206 (2012). 22959275 | 22959275 |
| 2390 | TARDBP | ARP35838_P050 | Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death. Acta Neuropathol. 130, 49-61 (2015). 25788357 | 25788357 |
| 2391 | TARDBP | ARP38941_T100 | Estes, P. S. et al. Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS. Hum. Mol. Genet. 20, 2308-21 (2011). 21441568 | 21441568 |
| 2392 | TARDBP | ARP38942_T100 | Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation. Biomolecules. 10, (2020). 32992901 | 32992901 |
| 2393 | TARDBP | AVARP00019_P050 | Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology. Biomolecules 2022 3 12 NULL 35327632 | 35327632 |
| 2394 | TAS2R3 | OAAF05229 | Analysis of the expression of human bitter taste receptors in extraoral tissues. Mol. Cell. Biochem. 426, 137-147 (2017). 28012014 | 28012014 |
| 2395 | TAS2R5 | OASG06985 | Analysis of the expression of human bitter taste receptors in extraoral tissues. Mol. Cell. Biochem. 426, 137-147 (2017). 28012014 | 28012014 |
| 2396 | TASK1 | ARP35090_T100 | Nogueira, E. F., Gerry, D., Mantero, F., Mariniello, B. & Rainey, W. E. The role of TASK1 in aldosterone production and its expression in normal adrenal and aldosterone-producing adenomas. Clin. Endocrinol. (Oxf). 73, 22-9 (2010). 19878209 | 19878209 |
| 2397 | TASK1 | ARP35090_T100 | Donner, B. C. et al. Functional role of TASK-1 in the heart: studies in TASK-1-deficient mice show prolonged cardiac repolarization and reduced heart rate variability. Basic Res. Cardiol. 106, 75-87 (2011). 20978771 | 20978771 |
| 2398 | TASK-1 | OAAF05983 | Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation. Circulation. 132, 82-92 (2015). 25951834 | 25951834 |
| 2399 | TAZ | OAAB05400 | Ciavarella, S., Dammacco, F., De Matteo, M., Loverro, G. & Silvestris, F. Umbilical cord mesenchymal stem cells: role of regulatory genes in their differentiation to osteoblasts. Stem Cells Dev. 18, 1211-20 (2009). 19125623 | 19125623 |
| 2400 | TBC1D24 | ARP57438_P050 | Clinical intrafamilial variability in lethal familial neonatal seizure disorder caused by TBC1D24 mutations. Am. J. Med. Genet. A. 170, 3207-3214 (2016). 27541164 | 27541164 |
| 2401 | TBC1D24 | ARP57438_P050 | The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons. Hum Mol Genet. 28, 584-597 (2019). 30335140 | 30335140 |
| 2402 | TBC1D24 | ARP57438_P050 | TBC1D24 regulates axonal outgrowth and membrane trafficking at the growth cone in rodent and human neurons. Cell Death Differ. 26, 2464-2478 (2019). 30858606 | 30858606 |
| 2403 | TBX15 | ARP47723_T100 | Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach. Clin Epigenetics. 7, 86 (2015). 26300991 | 26300991 |
| 2404 | TBX3 | ARP33412_T100 | Bozyk, P. D. et al. Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression. Stem Cells Dev. 20, 1995-2007 (2011). 21341990 | 21341990 |
| 2405 | TBX3 | ARP33412_T100 | Yano, T. et al. Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling. J. Cell Biol. 193, 319-32 (2011). 21482718 | 21482718 |
| 2406 | TBX5 | ARP33403_P050 | Lu, J. et al. Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos. J. Biomed. Sci. 18, 73 (2011). 21982178 | 21982178 |
| 2407 | TBX5 | ARP33403_P050 | Zhang, Y., Huang, L., Zuo, Z., Chen, Y. & Wang, C. Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling. Aquat. Toxicol. 142-143, 26-32 (2013). 23948075 | 23948075 |
| 2408 | TBX5 | ARP33403_P050 | Baban, A. et al. Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation. Am. J. Med. Genet. A 164A, 1419-24 (2014). 24664498 | 24664498 |
| 2409 | TBX5 | ARP33403_P050 | The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. Dev Cell. 36, 262-75 (2016). 26859351 | 26859351 |
| 2410 | TBX6 | ARP33404_P050 | Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20335662 | 20335662 |
| 2411 | TBX6 | ARP33405_P050 | Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864 | 18772864 |
| 2412 | TBX6 | ARP33405_P050 | Chen, Y.-L. et al. Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation. J. Biol. Chem. 284, 23481-90 (2009). 19561075 | 19561075 |
| 2413 | TBX6 | ARP33405_T100 | Cardiac commitment of primate embryonic stem cells.Nat Protoc1381-739September2008 | 18772864 |
| 2414 | Tcfap2c | ARP40141_T100 | Shim, J. H. et al. Proteomic analysis of time-dependent difference of protein expression profile changes during neuronal differentiation of mouse embryonic stem cells. Mol. Cells 29, 239-44 (2010). 20112072 | 20112072 |
| 2415 | TCHP | ARP60515_P050 | Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation. PLoS ONE. 11, e0143235 (2016). 26799392 | 26799392 |
| 2416 | TDP2 | ARP33010_P050 | Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. 45, 1159-1176 (2017). 28180300 | 28180300 |
| 2417 | TDP43 | ARP38942_T100 | Bannister, J. P. et al. Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J. Biol. Chem. 286, 15058-66 (2011). 21358643 | 21358643 |
| 2418 | TEAD1 | ARP39521_P050 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21527258 | 21527258 |
| 2419 | TEAD3 | ARP33429_P050 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21527258 | 21527258 |
| 2420 | TEAD4 | ARP33426_P050 | Chan, S. W. et al. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J. Biol. Chem. 284, 14347-58 (2009). 19324876 | 19324876 |
| 2421 | TEAD4 | ARP33426_P050 | YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers. PLoS Genet. 11, e1005465 (2015). 26295846 | 26295846 |
| 2422 | TEAD4 | ARP38276_P050 | Ribas, R. et al. Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments. Dev. Biol. 355, 372-80 (2011). 21527258 | 21527258 |
| 2423 | TEAD4 | ARP38276_P050 | Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol Cell Biol. 34, 1607-21 (2014). 24550007 | 24550007 |
| 2424 | TEAD4 | ARP38276_P050 | Identification of Quinolinols as Activators of TEAD-Dependent Transcription. ACS Chem Biol. 14, 2909-2921 (2019). 31742995 | 31742995 |
| 2425 | TEAD4 | ARP38276_P050 | Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Rep. 36, 109347 (2021) 34260916 | 34260916 |
| 2426 | Tecrl | ARP44592_P050 | TECRL deficiency results in aberrant mitochondrial function in cardiomyocytes.Commun Biol47051May2022 | 35577932 |
| 2427 | TEF | ARP37237_T100 | Lee, C. W. et al. Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina. J. Clin. Pathol. 64, 399-404 (2011). 21347262 | 21347262 |
| 2428 | TEKT3 | ARP57677_P050 | Intact Cell MALDI-TOF MS on Sperm: A Molecular Test For Male Fertility Diagnosis. Mol Cell Proteomics. 15, 1998-2010 (2016). 27044871 | 27044871 |
| 2429 | TENC1 | OAAF05467 | Deletion of the Tensin2 SH2-PTB domain, but not the loss of its PTPase activity, induces podocyte injury in FVB/N mouse strain. (2019). 31723089 | 31723089 |
| 2430 | Testosterone | OKCA00179 | Hypothyroidism: morphological and metabolic changes in the testis of adult albino rat and the amelioration by alpha lipoic acid. Folia Morphol (Warsz). NULL, NULL (2020). 32644186 | 32644186 |
| 2431 | Testosterone | OKCA00179 | Physiological Roles of Red Carrot Methanolic Extract and Vitamin E to Abrogate Cadmium-Induced Oxidative Challenge and Apoptosis in Rat Testes: Involvement of the Bax/Bcl-2 Ratio. Antioxidants (Basel). 10 (2021). 34829524 | 34829524 |
| 2432 | Testosterone | OKCA00352 | Multi-Approach Assessment for Stress Evaluation in Rainbow Trout Females, Oncorhynchus mykiss (Walbaum, 1792) from Three Different Farms during the Summer Season. Animals (Basel) 2021 6 11 NULL 34204450 | 34204450 |
| 2433 | TESTOSTERONE-3-BSA | OPMA04558 | Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. Am. J. Physiol. Heart Circ. Physiol. 310, H861-72 (2016). 26851246 | 26851246 |
| 2434 | TET2 | OAEB00839 | Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype. Breast Cancer Res. Treat. 153, 219-34 (2015). 26253945 | 26253945 |
| 2435 | TET2 | OAEB00839 | Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells. Oncol Lett. 15, 278-284 (2018). 29285192 | 29285192 |
| 2436 | TF | OASG07301 | Endogenous morphine in SH-SY5Y cells and the mouse cerebellum. PLoS One. 3, e1641 (2008) 18327293 | 18327293 |
| 2437 | TFAM | ARP31400_P050 | Shi, X. et al. Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells. J. Biol. Chem. 283, 30658-67 (2008). 18779333 | 18779333 |
| 2438 | TFAM | ARP31400_P050 | Walters, M. W., Bjork, J. A. & Wallace, K. B. Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats. Toxicology 264, 10-5 (2009). 19616056 | 19616056 |
| 2439 | TFAM | ARP31400_P050 | Miyazaki, T. et al. Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption. J. Biol. Chem. 287, 37808-23 (2012). 22988253 | 22988253 |
| 2440 | TFAM | ARP31400_P050 | Kemper, M. F., Zhao, Y., Duckles, S. P. & Krause, D. N. Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms. J. Cereb. Blood Flow Metab. 33, 122-8 (2013). 23093066 | 23093066 |
| 2441 | TFAM | ARP31400_P050 | Lu, W. et al. ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction. Cell Death Dis. 3, e422 (2012). 23152058 | 23152058 |
| 2442 | TFAM | ARP31400_P050 | Teodoro, J. S. et al. Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation. Mitochondrion 13, 637-46 (2013). 24041461 | 24041461 |
| 2443 | TFAM | ARP31400_P050 | Kemper, M. F., Stirone, C., Krause, D. N., Duckles, S. P. & Procaccio, V. Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection. Eur. J. Pharmacol. 723, 322-9 (2014). 24275351 | 24275351 |
| 2444 | TFAM | ARP31400_P050 | Vettor, R. et al. Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism. Am. J. Physiol. Endocrinol. Metab. 306, E519-28 (2014). 24381004 | 24381004 |
| 2445 | TFAM | ARP31400_P050 | Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53. Mitochondrion. 31, 33-39 (2016). 27650502 | 27650502 |
| 2446 | TFAM | ARP31400_P050 | Zc3h10 is a novel mitochondrial regulator. EMBO Rep. 19, (2018). 29507079 | 29507079 |
| 2447 | TFAM | ARP31400_P050 | Effect of aging on mitochondria and metabolism of bovine granulosa cells. J Reprod Dev. NULL, NULL (2020). 32921645 | 32921645 |
| 2448 | TFAM | ARP31400_P050 | Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction. J Cell Biol. 220 (2021). 33566069 | 33566069 |
| 2449 | TFAM | OAAB00276 | miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma. Oncotarget. 6, 15995-6018 (2015). 26201446 | 26201446 |
| 2450 | TFAM | OAAN00609 | Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution. Sci Rep. 10, 17033 (2020). 33046774 | 33046774 |
| 2451 | TFAM | ARP38484_P050 | TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A. Nat Commun 2022 1 13 653 35115527 | 35115527 |
| 2452 | Tfam | ARP45396_P050 | Propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating PPARG coactivator 1 alpha in hepatocytes. J Dairy Sci 2022 NULL NULL NULL 35181129 | 35181129 |
| 2453 | TFAP2A | OAAF01732 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 2454 | TFCP2L1 | OAED00192 | The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer. Exp Mol Med 2022 6 54 801-811 35729325 | 35729325 |
| 2455 | TG | | Characterization of Regulatory B Cells in Graves' Disease and Hashimoto's Thyroiditis. PLoS One 2015 5 10 e0127949 26016954 | 26016954 |
| 2456 | TGFB1 | OKCD06012 | MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts. Aging (Albany NY). 13, 6890-6903 (2021) 33621951 | 33621951 |
| 2457 | TGFB3 | ARP45448_P050 | Establishment of proprotein convertase, furinA knocked-out lines in medaka, Oryzias latipes, and unique form of medaka furin-like prorprotein convertase (mflPC). Comp. Biochem. Physiol. C Toxicol. Pharmacol. 178, 169-80 (2015). 26475985 | 26475985 |
| 2458 | TGFB3 | OKEH02925 | Macrophage Subpopulation Dynamics Shift following Intravenous Infusion of Mesenchymal Stromal Cells. Mol Ther. 28, 2007-2022 (2020) 32531238 | 32531238 |
| 2459 | TGFBR1 | OAAI00768 | Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. J Clin Invest. 127, 321-334 (2017). 27869651 | 27869651 |
| 2460 | TGFBR1 | OAAI00768 | Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium. PLoS One. 12, e0189522 (2017). 29253010 | 29253010 |
| 2461 | TGFBR1 | OAAI00768 | A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing. Nat Commun. 12, 1670 (2021) 33723267 | 33723267 |
| 2462 | TGFBR1 | OAEA00010 | Disulfiram Sensitizes a Therapeutic-Resistant Glioblastoma to the TGF-β Receptor Inhibitor. Int J Mol Sci 2021 19 22 NULL 34638842 | 34638842 |
| 2463 | TGM1 | OKCD01601 | Polarization of protease-activated receptor 2 (PAR-2) signaling is altered during airway epithelial remodeling and deciliation. J Biol Chem. 295, 6721-6740 (2020). 32241907 | 32241907 |
| 2464 | TGM2 | OAAF01946 | Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2. Cell. Mol. Life Sci. 72, 3009-35 (2015). 25943306 | 25943306 |
| 2465 | THBS1 | OKAG00254 | Quantitative Comparative Proteomics Reveals Candidate Biomarkers for the Early Prediction of Gestational Diabetes Mellitus: A Preliminary Study. In Vivo. 34, 517-525 (2020). 32111749 | 32111749 |
| 2466 | THIK-1 | ARP35347_P050 | Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage. Biochim. Biophys. Acta. 1863, 2766-2783 (2016). 27566292 | 27566292 |
| 2467 | Thoc4 | ARP43055_T100 | Ding, D., Enriquez-Algeciras, M., Dave, K. R., Perez-Pinzon, M. & Bhattacharya, S. K. The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis. EMBO Rep. 13, 230-6 (2012). 22261716 | 22261716 |
| 2468 | THRA | ARP34780_P050 | Kiss-Toth, E., Harlock, E., Lath, D., Quertermous, T. & Wilkinson, J. M. A TNF variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation. PLoS One 8, e76034 (2013). 24069456 | 24069456 |
| 2469 | THROMBOXANE A2 | OKEH02590 | Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis. Proc Natl Acad Sci U S A. 117, 10958-10969 (2020). 32366656 | 32366656 |
| 2470 | THYROGLOBULIN | OPSA10707 | Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis. Clinical & Experimental Immunology. 180, 58-69 (2015). 25412700 | 25412700 |
| 2471 | Thyroxine | OKCA00349 | Waterborne exposure to avobenzone and octinoxate induces thyroid endocrine disruption in wild-type and thrαa-/- zebrafish larvae. Ecotoxicology 2022 6 31 948-955 35622199 | 35622199 |
| 2472 | TIPARP | ARP33763_P050 | MacPherson, L. et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. Nucleic Acids Res. 41, 1604-21 (2013). 23275542 | 23275542 |
| 2473 | TJP1 | OKDD00562 | Tight junction protein ZO-1 in Kawasaki disease. BMC Pediatr. 21, 157 (2021) 33789621 | 33789621 |
| 2474 | TLR2 | ARP30551_P050 | Expression of Toll-like receptors 2, 4 and 6 in equine endometrial epithelial cells: A comparative in situ and in vitro study. Res. Vet. Sci. 112, 34-41 (2017). 28119161 | 28119161 |
| 2475 | TLR2 | ARP30551_P050 | Expression of Toll-like receptors 2, 4 and 6 in different cell populations of the equine endometrium. Vet. Immunol. Immunopathol. 185, 7-13 (2017). 28242004 | 28242004 |
| 2476 | TM6SF2 | ARP44400_P050 | Holmen, O. L. et al. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat. Genet. 46, 345-51 (2014). 24633158 | 24633158 |
| 2477 | TM6SF2 | ARP44400_P050 | Sookoian, S. et al. Genetic variation in TM6SF2 and the risk of nonalcoholic fatty liver disease and histological disease severity. Hepatology (2014). doi:10.1002/hep.27556 25302781 | 25302781 |
| 2478 | TM9SF1 | ARP44683_T100 | He, P. et al. High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene. Autophagy 5, 52-60 (2009). 19029833 | 19029833 |
| 2479 | TM9SF1 | ARP44683_T100 | Extracellular vesicle-mediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression. Oncogenesis. 7, 7 (2018). 29362448 | 29362448 |
| 2480 | TMB | OORA01684 | Differential internalin A levels in biofilms of Listeria monocytogenes grown on different surfaces and nutrient conditions. Int. J. Food Microbiol. 219, 50-5 (2016). 26724402 | 26724402 |
| 2481 | TMCO1 | ARP49429_P050 | Burdon, K. P. et al. Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nat. Genet. 43, 574-8 (2011). 21532571 | 21532571 |
| 2482 | TMCO1 | ARP49429_P050 | Sharma, S. et al. Association of genetic variants in the TMCO1 gene with clinical parameters related to glaucoma and characterization of the protein in the eye. Invest. Ophthalmol. Vis. Sci. 53, 4917-25 (2012). 22714896 | 22714896 |
| 2483 | TMEM135 | ARP49773_P050 | Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. Elife. 5, (2016). 27863209 | 27863209 |
| 2484 | TMEM16A | ARP42506_P050 | Banga, A., Flaig, S., Lewis, S., Winfree, S. & Blazer-Yost, B. L. Epinephrine stimulation of anion secretion in the Calu-3 serous cell model. Am. J. Physiol. Lung Cell. Mol. Physiol. 306, L937-46 (2014). 24705724 | 24705724 |
| 2485 | TMEM16A | ARP42506_P050 | Liu, Y. et al. Characterization of the effects of Cl(-) channel modulators on TMEM16A and bestrophin-1 Ca(2+) activated Cl (-) channels. Pflugers Arch. (2014). doi:10.1007/s00424-014-1572-5 25078708 | 25078708 |
| 2486 | TMEM173 | ARP48041_P050 | Duan, X. et al. Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts. Mol. Cancer Res. 9, 589-602 (2011). 21471287 | 21471287 |
| 2487 | TMEM173 | ARP48041_P050 | Panchanathan, R., Liu, H., Xin, D. & Choubey, D. Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING. Innate Immun. (2013). doi:10.1177/1753425913507097 24131791 | 24131791 |
| 2488 | TMEM2 | ARP42381_P050 | Zhao, Q. et al. Rare inborn errors associated with chronic hepatitis B virus infection. Hepatology 56, 1661-70 (2012). 22610944 | 22610944 |
| 2489 | TMEM2 | ARP42382_P050 | TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK-STAT signaling pathway. Cell Death Dis. 7, e2239 (2016). 27253403 | 27253403 |
| 2490 | TMEM24 | ARP47081_P050 | Pottekat, A. et al. Insulin biosynthetic interaction network component, TMEM24, facilitates insulin reserve pool release. Cell Rep. 4, 921-30 (2013). 24012759 | 24012759 |
| 2491 | TMEM48 | ARP46268_P050 | Tarazón, E. et al. Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes. PLoS One 7, e48957 (2012). 23152829 | 23152829 |
| 2492 | TMEM97 | OAAB22200 | Riad, A et al. Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex. Sci Rep. 2018; 8: 16845. 30443021 | 30443021 |
| 2493 | TMPRSS3 | ARP57684_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2494 | TMTC2 | ARP48445_P050 | TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3. Redox Biol 2021 NULL 48 102193 34839142 | 34839142 |
| 2495 | TNFAIP3 | OKCD08256 | Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis. J Lipid Res. 61, 1764-1775 (2020). 33008925 | 33008925 |
| 2496 | TNFAIP3 | OKCD08256 | Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis. J Lipid Res. 61, 1764-1775 (2020). 33531252 | 33531252 |
| 2497 | TNFAIP3 | OKCD08256 | Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis. J Lipid Res. 61, 1764-1775 (2020). 33455718 | 33455718 |
| 2498 | TNFRSF12A | OKEH01840 | Biofluid quantification of TWEAK/Fn14 axis in combination with a selected biomarker panel improves assessment of prostate cancer aggressiveness. J Transl Med. 17, 307 (2019). 31500625 | 31500625 |
| 2499 | TNNI1 | ARP42117_P050 | Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle. Proteomics. 16, 2019-27 (2016). 27214824 | 27214824 |
| 2500 | TNNI3 | ARP41391_P050 | Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations. Circ Res. 124, 1228-1239 (2019). 30732532 | 30732532 |
| 2501 | TNNT2 | OKEH04575 | Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF‑κB signalling pathway in diabetic cardiomyopathy rats. Mol Med Rep. 23, 1 (2021). 33495841 | 33495841 |
| 2502 | TNNT3 | ARP51286_P050 | Zhang, T. et al. Troponin T nuclear localization and its role in aging skeletal muscle. Age (Dordr). 35, 353-70 (2013). 22189912 | 22189912 |
| 2503 | TNNT3 | ARP51287_T100 | Zhang, T., Birbrair, A. & Delbono, O. Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis. Cytoskeleton (Hoboken). 70, 134-47 (2013). 23378072 | 23378072 |
| 2504 | TNNT3 | ARP51287_T100 | Troponin T3 regulates nuclear localization of the calcium channel Cavβ1a subunit in skeletal muscle. Exp Cell Res. 336, 276-86 (2015). 25981458 | 25981458 |
| 2505 | TNNT3 | ARP51287_T100 | Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice. Aging Cell. 15, 488-98 (2016). 26892246 | 26892246 |
| 2506 | TNRC5 | ARP34422_P050 | The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir. Res. 16, 147 (2015). 26646719 | 26646719 |
| 2507 | TNS1 | OAEB00321 | Gonadotropin-releasing hormone agonist induces downregulation of tensin 1 in women with endometriosis. Acta Obstet Gynecol Scand. 98, 222-231 (2019) 30312486 | 30312486 |
| 2508 | TOR3A | ARP33117_P050 | The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn. Nat Commun. 10, 3262 (2019). 31332180 | 31332180 |
| 2509 | TORSIN3 | ARP33117_P050 | Jungwirth, M., Dear, M. L., Brown, P., Holbrook, K. & Goodchild, R. Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA. Hum. Mol. Genet. 19, 888-900 (2010). 20015956 | 20015956 |
| 2510 | TOX4 | ARP39145_P050 | Lee, J.-H., You, J., Dobrota, E. & Skalnik, D. G. Identification and characterization of a novel human PP1 phosphatase complex. J. Biol. Chem. 285, 24466-76 (2010). 20516061 | 20516061 |
| 2511 | TPM2 | ARP48224_T100 | Abdul-Hussein, S., Rahl, K., Moslemi, A.-R. & Tajsharghi, H. Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures. PLoS One 8, e72396 (2013). 24039757 | 24039757 |
| 2512 | TRAAK | ARP35380_P050 | Bogdan, R. et al. 5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques. Neurosci. Lett. 503, 83-6 (2011). 21871532 | 21871532 |
| 2513 | TRAF3IP1 | ARP55316_P050 | Integrin a8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells. J Cell Sci. 130, 3698-3712 (2017). 28883094 | 28883094 |
| 2514 | TRAIL | AVARP02040_P050 | Ceballos, M. P. et al. FoxO3a Nuclear Localization and Its Association with beta-Catenin and Smads in IFN-a-Treated Hepatocellular Carcinoma Cell Lines. J. Interferon Cytokine Res. doi:10.1089/jir.2013.0124 (2014). 24950290 | 24950290 |
| 2515 | Tri-iodothyronine | OKCA00348 | Waterborne exposure to avobenzone and octinoxate induces thyroid endocrine disruption in wild-type and thrαa-/- zebrafish larvae. Ecotoxicology 2022 6 31 948-955 35622199 | 35622199 |
| 2516 | TRIM14 | ARP34737_P050 | Zhou, Z. et al. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proc. Natl. Acad. Sci. U. S. A. 111, E245-54 (2014). 24379373 | 24379373 |
| 2517 | TRIM14 | ARP34737_P050 | TRIM14 promotes endothelial activation via activating NF-κB signaling pathway. J Mol Cell Biol. 12, 176-189 (2020). 31070748 | 31070748 |
| 2518 | TRIM14 | ARP34737_P050 | TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection. J Immunol. 205, 153-167 (2020). 32404352 | 32404352 |
| 2519 | TRIM32 | ARP31692_P050 | Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum Mol Genet. 18, 1353-67 (2009). 19155210 | 19155210 |
| 2520 | TRIM32 | ARP38965_T100 | Kudryashova, E., Wu, J., Havton, L. A. & Spencer, M. J. Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum. Mol. Genet. 18, 1353-67 (2009). 19155210 | 19155210 |
| 2521 | TRIM32 | ARP38965_T100 | Streich, F. C., Ronchi, V. P., Connick, J. P. & Haas, A. L. Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanism. J. Biol. Chem. 288, 8209-21 (2013). 23408431 | 23408431 |
| 2522 | TRIM41 | ARP34763_P050 | TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Influenza A Virus Infection. J Virol. 92, (2018). 29899090 | 29899090 |
| 2523 | TRIM41 | ARP34763_P050 | TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Vesicular Stomatitis Virus Infection. Viruses. 12, (2020). 31979016 | 31979016 |
| 2524 | TRIM65 | OAAB08057 | LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65. Mol Med Rep. 24 (2021). 34498706 | 34498706 |
| 2525 | TRIM72 | ARP42970_P050 | Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. Cardiovasc Res. 110, 178-87 (2016). 26790476 | 26790476 |
| 2526 | TRIM72 | ARP42971_P050 | Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. Cardiovasc. Res. 110, 178-87 (2016). 26790476 | 26790476 |
| 2527 | TRIM72 | ARP42971_P050 | Xiaofei Cong, et al. TRIM72 promotes alveolar epithelial cell membrane repair and ameliorates lung fibrosis. 132 (2020). 32471489 | 32471489 |
| 2528 | TRIM72 | OAEB00972 | Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor. Cardiovasc Res. 110, 178-87 (2016). 26790476 | 26790476 |
| 2529 | TRIM75 | OAAB13204 | Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with Duchenne or Becker muscular dystrophy. Hum Mol Genet. 27, 451-462 (2018). 29194514 | 29194514 |
| 2530 | TRIML2 | ARP55636_P050 | STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus. PLoS Pathog. 14, e1007416 (2018). 30532138 | 30532138 |
| 2531 | TRIP12 | OAAB20005 | Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding. Nucleic Acids Res. 48, 9415-9432 (2020). 32658293 | 32658293 |
| 2532 | TRIP6 | ARP51617_P050 | The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res. 16, 147 (2015). 26646719 | 26646719 |
| 2533 | TRP53 | ARP37163_T100 | Methylsulfonylmethane inhibits cortisol-induced stress through p53-mediated SDHA/HPRT1 expression in racehorse skeletal muscle cells: A primary step against exercise stress. Exp Ther Med. 19, 214-222 (2020). 31853292 | 31853292 |
| 2534 | TRPA1 | ARP35205_P050 | Rohn, T. T., Catlin, L. W., Coonse, K. G. & Habig, J. W. Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer’s disease brain. Brain Res. 1475, 106-15 (2012). 22905134 | 22905134 |
| 2535 | TRPA1 | ARP35205_P050 | Pierce, A. N., Ryals, J. M., Wang, R. & Christianson, J. A. Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice. Neuroscience 263, 216-30 (2014). 24462609 | 24462609 |
| 2536 | TRPA1 | ARP35205_P050 | TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress. Brain. 139, 1361-77 (2016). 26984186 | 26984186 |
| 2537 | TRPA1 | ARP35205_P050 | TRPA1 receptor is upregulated in human oral lichen planus. Oral Dis. 23, 189-198 (2017). 27718297 | 27718297 |
| 2538 | TRPA1 | ARP35205_P050 | TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice. Cell Death Dis. 11, 633 (2020). 32801314 | 32801314 |
| 2539 | TRPA1 | ARP48070_P050 | Upregulation of extraneuronal TRPV1 expression in chronic rhinosinusitis with nasal polyps. Rhinology 2018 3 56 245-254 29476616 | 29476616 |
| 2540 | TRPA1 | ARP35205_P050 | No functional TRPA1 in cardiomyocytes.Acta Physiol (Oxf)e136592324August2021 | 33819369 |
| 2541 | TRPM2 | ARP44380_P050 | TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1. J Clin Invest. 124, 4989-5001 (2014). 25295536 | 25295536 |
| 2542 | TRPM3 | ARP36768_T100 | Takumida, M., Ishibashi, T., Hamamoto, T., Hirakawa, K. & Anniko, M. Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear. Acta Otolaryngol. 129, 1050-60 (2009). 19065290 | 19065290 |
| 2543 | TRPM4 | ARP35268_P050 | Kuras, Z., Yun, Y.-H., Chimote, A. A., Neumeier, L. & Conforti, L. KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells. PLoS One 7, e43859 (2012). 22952790 | 22952790 |
| 2544 | TRPM4 | ARP35268_P050 | Age-dependent decrease in TRPM4 channel expression but not trafficking alters urinary bladder smooth muscle contractility. Physiol Rep. 9, e14754 (2021). 33625779 | 33625779 |
| 2545 | TRPM5 | ARP35242_P050 | The Role of Cholecystokinin in Peripheral Taste Signaling in Mice. Front Physiol. 8, 866 (2017). 29163209 | 29163209 |
| 2546 | TRPV1 | OKCD02958 | Comparison of the expression of neurotransmitter and muscular genesis markers in the postnatal male mouse masseter and trigeminal ganglion during development.J Neurosci Res1043-1055966June2018 | 29265492 |
| 2547 | TRPV4 | ARP35416_P050 | Sampat, S. R. et al. Applied osmotic loading for promoting development of engineered cartilage. J. Biomech. 46, 2674-81 (2013). 24035014 | 24035014 |
| 2548 | TSC22D4 | ARP30107_T100 | Canterini, S., Bosco, A., De Matteis, V., Mangia, F. & Fiorenza, M. T. THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis. Mol. Cell. Neurosci. 40, 249-57 (2009). 19084601 | 19084601 |
| 2549 | TSC22D4 | ARP30107_T100 | Canterini, S. et al. Subcellular TSC22D4 localization in cerebellum granule neurons of the mouse depends on development and differentiation. Cerebellum 11, 28-40 (2012). 20878296 | 20878296 |
| 2550 | TSC22D4 | ARP30107_T100 | NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. Cell Rep. 30, 3478-3491.e6 (2020). 32160551 | 32160551 |
| 2551 | TSC22D4 | ARP37339_T100 | Canterini, S., Carletti, V., Nusca, S., Mangia, F. & Fiorenza, M. T. Multiple TSC22D4 iso-/phospho-glycoforms display idiosyncratic subcellular localizations and interacting protein partners. FEBS J. 280, 1320-9 (2013). 23305244 | 23305244 |
| 2552 | TSC22D4 | ARP37339_T100 | GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance. Development. 145, (2018). 30126904 | 30126904 |
| 2553 | TSG101 | ARP37310_T100 | Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission. Methods Mol. Biol. 1545, 153-176 (2017). 27943213 | 27943213 |
| 2554 | TSHR | ARP41871_P050 | Pessina, P., Castillo, V., Sartore, I., Borrego, J. & Meikle, A. Semiquantitative immunohistochemical marker staining and localization in canine thyroid carcinoma and normal thyroid gland. Vet. Comp. Oncol. (2014). doi:10.1111/vco.12111 25082554 | 25082554 |
| 2555 | TSPAN12 | ARP46887_P050 | Norrin restores blood-retinal barrier properties after vascular endothelial growth factor-induced permeability. J Biol Chem. 295, 4647-4660 (2020). 32086377 | 32086377 |
| 2556 | TSPO | OALA05219 | Organoid-derived C-Kit+/SSEA4- human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents. Nat Commun. 10, 1205 (2019). 30872578 | 30872578 |
| 2557 | TTK | OAAF01564 | Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget. 9, 3081-3088 (2018). 29423030 | 29423030 |
| 2558 | TTLL5 | ARP75440_P050 | Zhen Xiong, et al. Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis. (2020). 31699823 | 31699823 |
| 2559 | TTR | OKEH02948 | Jonathan C Fox, et al. First-in-Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers. (2019). 31172685 | 31172685 |
| 2560 | TTR | OKIA00111 | Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice. Nat Commun. 12, 2770 (2021) 33986266 | 33986266 |
| 2561 | TTRAP | ARP33010_P050 | Xu, G.-L. et al. TTRAP is a novel PML nuclear bodies-associated protein. Biochem. Biophys. Res. Commun. 375, 395-8 (2008). 18706885 | 18706885 |
| 2562 | TTRAP | ARP33010_P050 | Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. Nucleic Acids Res. (2016). 27789688 | 27789688 |
| 2563 | TTYH3 | ARP49946_P050 | TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway.Int J Mol SciNULL2318September2022 | 36142409 |
| 2564 | TUBB2A | ARP40177_P050 | Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA. PLoS ONE. 11, e0160694 (2016). 27513867 | 27513867 |
| 2565 | TUBB3 | ARP63784_P050 | CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium. Sci Rep. 6, 25507 (2016). 27145700 | 27145700 |
| 2566 | TUBB6 | ARP60382_P050 | Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates. Sci Rep. 8, 10004 (2018). 29968775 | 29968775 |
| 2567 | TUFM | ARP58546_P050 | Clemente, P. et al. hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria. J. Biol. Chem. 288, 8321-31 (2013). 23362268 | 23362268 |
| 2568 | TWIST1 | ARP37997_T100 | Guha, P. et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, a9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res. Treat. 145, 5-22 (2014). 24668500 | 24668500 |
| 2569 | TWIST1 | ARP37997_T100 | Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 26, 222-34 (2014). 25117710 | 25117710 |
| 2570 | TWIST1 | OKCD08266 | The association between HPV gene expression, inflammatory agents and cellular genes involved in EMT in lung cancer tissue. BMC Cancer. 20, 916 (2020). 32972386 | 32972386 |
| 2571 | TWIST1 | OKCD08266 | Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer. BMC Cancer 2021 1 21 926 34399719 | 34399719 |
| 2572 | TWNK | ARP36483_P050 | Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution. Sci Rep. 10, 17033 (2020). 33046774 | 33046774 |
| 2573 | TYR1 | ARP44315_P050 | Horibe, I. et al. Induction of melanogenesis by 4’-O-methylated flavonoids in B16F10 melanoma cells. J. Nat. Med. 67, 705-10 (2013). 23208771 | 23208771 |
| 2574 | U1A | ARP40275_P050 | Wang, E., Mueller, W. F., Hertel, K. J. & Cambi, F. G Run-mediated recognition of proteolipid protein and DM20 5’ splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site. J. Biol. Chem. 286, 4059-71 (2011). 21127064 | 21127064 |
| 2575 | Uba1 | ARP58687_P050 | Rogers, L. M., Olivier, A. K., Meyerholz, D. K. & Dupuy, A. J. Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer. J. Immunol. 190, 4393-9 (2013). 23475219 | 23475219 |
| 2576 | UBE2E1 | ARP35260_P050 | Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1. Elife 2022 NULL 11 NULL 35170427 | 35170427 |
| 2577 | UBE2E2 | ARP43437_P050 | Hans, F. et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J. Biol. Chem. 289, 19164-79 (2014). 24825905 | 24825905 |
| 2578 | UBE2K | ARP58011_P050 | Fromm-Dornieden, C. et al. Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells. BMC Mol. Biol. 13, 9 (2012). 22436005 | 22436005 |
| 2579 | Ube2n | ARP34089_T100 | Xu, B. J. et al. Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts. Proteomics 10, 2458-70 (2010). 20405477 | 20405477 |
| 2580 | UBE2T | ARP40102_T100 | CaMKII-δ9 Induces Cardiomyocyte Death to Promote Cardiomyopathy and Heart Failure. Front Cardiovasc Med 2022 NULL 8 820416 35127874 | 35127874 |
| 2581 | UBQLN4 | ARP57355_P050 | Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease. Brain Res. 1597, 37-46 (2015). 25511991 | 25511991 |
| 2582 | UCHL1 | OKEH01247 | Ubiquitin carboxyl-terminal esterase L1 is not elevated in the serum of concussed rugby players: an observational cross-sectional study. Sci Rep 2022 1 12 12230 35851288 | 35851288 |
| 2583 | UCN2 | OKEH03365 | Protective effects of urocortin 2 against caerulein-induced acute pancreatitis. PLoS One. 14, e0217065 (2019). 31100090 | 31100090 |
| 2584 | ULK1 | OABF01248 | The Combination of Fasting, Acute Resistance Exercise, and Protein Ingestion Led to Different Responses of Autophagy Markers in Gastrocnemius and Liver Samples. Nutrients. 12, (2020). 32121154 | 32121154 |
| 2585 | ULK1 | OABF01248 | Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis. Autophagy. NULL, 1-17 (2020). 33078654 | 33078654 |
| 2586 | ULK1 | OABF01248 | Genetic deletion of IL-6 increases CK-MB, a classic cardiac damage marker, and decreases UPRmt genes after exhaustive exercise.Cell Biochem Funct369-378404June2022 | 35411956 |
| 2587 | ULK1 | OABF01248 | Chronic rapamycin treatment decreases hepatic IL-6 protein, but increases autophagy markers as a protective effect against the overtraining-induced tissue damage.Clin Exp Pharmacol Physiol893-902498August2022 | 35637552 |
| 2588 | Uncx4.1 | ARP47548_P050 | Chen, X. et al. Characterization of zebrafish pax1b and pax9 in fin bud development. Biomed Res. Int. 2014, 309385 (2014). 25197636 | 25197636 |
| 2589 | UPB1 | ARP42467_T100 | Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 | 24465277 |
| 2590 | UPB1 | ARP42467_T100 | Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma. BMC Cancer. 16, 795 (2016). 27733154 | 27733154 |
| 2591 | UPF3B | ARP40998_T100 | RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep. 7, 41517 (2017). 28128343 | 28128343 |
| 2592 | UPF3B | ARP40998_T100 | Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins. J Cell Sci. 130, 3009-3022 (2017). 28743738 | 28743738 |
| 2593 | URH49 | ARP36384_T100 | Majerciak, V., Deng, M. & Zheng, Z.-M. Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57. Virology 407, 206-12 (2010). 20828777 | 20828777 |
| 2594 | USE1 | ARP39361_P050 | Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res. 70, 1344-55 (2010). 20124481 | 20124481 |
| 2595 | USP7 | ARP59057_P050 | Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. Biol. Reprod. 94, 31 (2016). 26607717 | 26607717 |
| 2596 | USP8 | OKCD00957 | Inhibiting USP8 overcomes hepatocellular carcinoma resistance via suppressing receptor tyrosine kinases. Aging (Albany NY) 2021 11 13 14999-15012 34081623 | 34081623 |
| 2597 | VAMP8 | ARP59536_P050 | Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties. J Histochem Cytochem. 65, 637-653 (2017). 28914590 | 28914590 |
| 2598 | VANGL2 | OAAB15535 | Heterozygous Vangl2(Looptail) mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech. 10, 409-423 (2017). 28237967 | 28237967 |
| 2599 | VARS | ARP46151_P050 | Duarte, M. & Videira, A. Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa. Biochem. J. 448, 297-306 (2012). 22957697 | 22957697 |
| 2600 | V-ATPASE | ARP49516_P050 | Anoctamins, a novel family of ion channels and their role in intracellular calcium signaling. Journal of Cell Science. 125, 4991-4998 (2015). 22946059 | 22946059 |
| 2601 | VDAC1 | ARP35122_T100 | Chen, S. et al. Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins. J. Proteome Res. 8, 5196-211 (2009). 19775189 | 19775189 |
| 2602 | VDAC1 | ARP35122_T100 | Arduíno, D. M. et al. Mitochondrial metabolism in Parkinson’s disease impairs quality control autophagy by hampering microtubule-dependent traffic. Hum. Mol. Genet. 21, 4680-702 (2012). 22843496 | 22843496 |
| 2603 | VDAC1 | ARP35122_T100 | Rousset, F., Nguyen, M. V. C., Grange, L., Morel, F. & Lardy, B. Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes. PLoS One 8, e66478 (2013). 23840483 | 23840483 |
| 2604 | VDAC2 | ARP35123_P050 | Hrabakova, R. et al. Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. J. Proteome Res. 12, 455-69 (2013). 23151231 | 23151231 |
| 2605 | VDAC3 | ARP35180_P050 | Majumder, S., Slabodnick, M., Pike, A., Marquardt, J. & Fisk, H. A. VDAC3 regulates centriole assembly by targeting Mps1 to centrosomes. Cell Cycle 11, 3666-78 (2012). 22935710 | 22935710 |
| 2606 | VDAC3 | ARP35180_P050 | Majumder, S. & Fisk, H. A. VDAC3 and Mps1 negatively regulate ciliogenesis. Cell Cycle 12, 849-58 (2013). 23388454 | 23388454 |
| 2607 | VDAC3 | ARP35180_P050 | Non-Overlapping Distributions and Functions of the VDAC Family in Ciliogenesis. Cells. 4, 331-53 (2015). 26264029 | 26264029 |
| 2608 | VEGFC | OKEH00240 | Vascular endothelial growth factor-C ameliorates renal interstitial fibrosis through lymphangiogenesis in mouse unilateral ureteral obstruction. Lab Invest. 97, 1439-1452 (2017). 29083411 | 29083411 |
| 2609 | VIP | OKEH00406 | ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson's Disease. Neuron. 98, 1155-1169.e6 (2018). 29887339 | 29887339 |
| 2610 | VMD2L2 | ARP35424_T100 | Milenkovic, V. M., Soria, R. B., Aldehni, F., Schreiber, R. & Kunzelmann, K. Functional assembly and purinergic activation of bestrophins. Pflugers Arch. 458, 431-41 (2009). 19130075 | 19130075 |
| 2611 | VPS52 | ARP57644_P050 | Vaccinia virus uses retromer-independent cellular retrograde transport pathways to facilitate the wrapping of intracellular mature virions during viral morphogenesis. J. Virol. (2016). 27581988 | 27581988 |
| 2612 | WARS2 | ARP52366_P050 | Wars2 is a determinant of angiogenesis. Nat Commun. 7, 12061 (2016). 27389904 | 27389904 |
| 2613 | WASF3 | OAEC03197 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 2614 | WDFY3 | ARP50850_P050 | Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration. Autophagy. 12, 2439-2450 (2016). 27753525 | 27753525 |
| 2615 | WDR45 | OAAB09622 | TRAPPC11 functions in autophagy by recruiting ATG2B-WIPI4/WDR45 to preautophagosomal membranes.Traffic325-345205May2019 | 30843302 |
| 2616 | WEST NILE VIRUS ENVELOPE PROTEIN | OPMA04745 | Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing. Integrative Biology. 7, 1587-1597 (2015). 26481611 | 26481611 |
| 2617 | WHSC1 | ARP33489_P050 | Li, J. et al. Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas. Neuro. Oncol. 10, 45-51 (2008). 18182627 | 18182627 |
| 2618 | WNT1 | OKEH04852 | PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression. Nat Commun. 10, 5716 (2019). 31844057 | 31844057 |
| 2619 | WNT10A | OKEH03519 | Whitson JA et al. Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis. Invest Ophthalmol Vis Sci. 58, 2666 - 2684 (2017). 28525556 | 28525556 |
| 2620 | Wnt2B | ARP41254_P050 | Chigita, S. et al. CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of beta-catenin in carcinoma cells. Int. J. Oncol. 41, 2021-8 (2012). 23076981 | 23076981 |
| 2621 | WNT3 | OKCD00611 | Nicotine enhances mesangial cell proliferation and fibronectin production in high glucose milieu via activation of Wnt/β-catenin pathway. Biosci Rep. 38, (2018). 29572389 | 29572389 |
| 2622 | WNT3A | OKCD09406 | PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression. Nat Commun. 10, 5716 (2019). 31844057 | 31844057 |
| 2623 | WNT5A | OKEH00723 | Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia. Cell Stem Cell. 22, 951-959.e3 (2018). 29859176 | 29859176 |
| 2624 | WNT5A | OKEH00723 | Cigarette Smoke-Induced Pulmonary Inflammation Becomes Systemic by Circulating Extracellular Vesicles Containing Wnt5a and Inflammatory Cytokines. Front Immunol. 9, 1724 (2018). 30090106 | 30090106 |
| 2625 | WNT5A | OKEH00723 | Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia. Blood. 134, 1084-1094 (2019). 31409670 | 31409670 |
| 2626 | WNT5A | OKEH04420 | YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity. Cell Death Dis 2022 4 13 407 35478181 | 35478181 |
| 2627 | Wnt7b | ARP41291_P050 | Gore, A. J., Deitz, S. L., Palam, L. R., Craven, K. E. & Korc, M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation. J. Clin. Invest. 124, 338-52 (2014). 24334458 | 24334458 |
| 2628 | WNT7B | OAAN02407 | Lijie Zhao, et al. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. 522-532 (2020). 32928363 | 32928363 |
| 2629 | WT1 | OACD04962 | Antileukaemic Cell Proliferation and Cytotoxic Activity of Edible Golden Cordyceps (Cordyceps militaris) Extracts. Evid Based Complement Alternat Med 2022 NULL 2022 5347718 35497915 | 35497915 |
| 2630 | WWP2 | ARP43089_P050 | WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nat Commun. 10, 3616 (2019). 31399586 | 31399586 |
| 2631 | XAF1 | OAAB14914 | SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease. J Exp Med. 216, 743-756 (2019). 30842236 | 30842236 |
| 2632 | XBP1 | ARP38553_P050 | Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. PLoS One. 10, e0115723 (2015). 25695253 | 25695253 |
| 2633 | XDH | OAAB05869 | Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. J Physiol. 594, 1327-40 (2016). 26574162 | 26574162 |
| 2634 | XK | ARP33809_P050 | Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum. Front Synaptic Neurosci. 13, 618391 (2021). 33815086 | 33815086 |
| 2635 | XPOT | ARP40711_P050 | The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals. Elife. 10, NULL (2021) 33646118 | 33646118 |
| 2636 | YAP1 | ARP50530_P050 | Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma. Cancers (Basel). 13 (2021). 33803512 | 33803512 |
| 2637 | YTHDF2 | ARP67917_P050 | A potentially abundant junctional RNA motif stabilized by m6A and Mg2. Nat Commun. 9, 2761 (2018). 30018356 | 30018356 |
| 2638 | YTHDF2 | ARP67917_P050 | m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 20, 1074-1083 (2018). 30154548 | 30154548 |
| 2639 | YTHDF2 | ARP67917_P050 | m6A enhances the phase separation potential of mRNA. Nature. 571, 424-428 (2019). 31292544 | 31292544 |
| 2640 | YTHDF2 | ARP67917_P050 | Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 31, 107819 (2020). 32610122 | 32610122 |
| 2641 | YTHDF2 | ARP67917_P050 | YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways. Cell Rep. 32, 108120 (2020). 32905781 | 32905781 |
| 2642 | YTHDF2 | ARP67917_P050 | Context-dependent functional compensation between Ythdf m6A reader proteins. Genes Dev. 34, 1373-1391 (2020) 32943573 | 32943573 |
| 2643 | YTHDF2 | ARP67917_P050 | Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer. Mol Cell. 81, 3048-3064.e9 (2021) 34216543 | 34216543 |
| 2644 | YTHDF2 | ARP67917_P050 | EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. Nat Commun. 12, 177 (2021). 33420027 | 33420027 |
| 2645 | YTHDF2 | ARP67917_P051 | The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells. Cancer Discov 2021 2 11 480-499 33023892 | 33023892 |
| 2646 | ZBTB32 | OACA06573 | ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation. iScience 2021 7 24 102790 34337361 | 34337361 |
| 2647 | ZBTB4 | ARP31937_P050 | Kim, K. et al. Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters. Mol. Cancer Ther. 11, 1852-62 (2012). 22752225 | 22752225 |
| 2648 | Zbtb43 | ARP39048_P050 | Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome.Nat Cell Biol1141-1153247July2022 | 35787683 |
| 2649 | ZC3H10 | ARP60671_P050 | Zc3h10 is a novel mitochondrial regulator. EMBO Rep. 19, (2018). 29507079 | 29507079 |
| 2650 | ZC3H10 | ARP60671_P050 | Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction. J Cell Biol. 220 (2021). 33566069 | 33566069 |
| 2651 | ZCCHC17 | OAAB01037 | Ribosomal protein pNO40 mediates nucleolar sequestration of SR family splicing factors and its overexpression impairs mRNA metabolism. Cell. Signal. 32, 12-23 (2017). 28069438 | 28069438 |
| 2652 | ZEB1 | ARP30976_P050 | Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158 | 20547158 |
| 2653 | ZEB1 | ARP32422_P050 | Lobert, S., Graichen, M. E. & Morris, K. Coordinated regulation of beta-tubulin isotypes and epithelial-to-mesenchymal transition protein ZEB1 in breast cancer cells. Biochemistry 52, 5482-90 (2013). 23869586 | 23869586 |
| 2654 | ZEB2 | ARP39141_P050 | Rogers, C. D., Saxena, A. & Bronner, M. E. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J. Cell Biol. 203, 835-47 (2013). 24297751 | 24297751 |
| 2655 | ZEB2 | ARP39141_P050 | Guan, H. et al. Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2. Endocrine. doi:10.1007/s12020-014-0326-7 (2014). 24968735 | 24968735 |
| 2656 | ZFAND5 | ARP34409_P050 | He, G., Sun, D., Ou, Z. & Ding, A. The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3’-untranslated regions. J. Biol. Chem. 287, 24967-77 (2012). 22665488 | 22665488 |
| 2657 | ZFP148 | ARP34536_P050 | Hemida, M. G. et al. MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148. Cell. Mol. Life Sci. 70, 277-91 (2013). 22842794 | 22842794 |
| 2658 | ZFP191 | ARP33519_P050 | Lv, L. et al. Zinc finger protein 191 deficiency attenuates vascular smooth muscle cell proliferation, migration, and intimal hyperplasia after endovascular arterial injury. J. Vasc. Surg. (2013). doi:10.1016/j.jvs.2013.03.049 23755975 | 23755975 |
| 2659 | ZFP36 | ARP34385_P050 | Fähling, M. et al. Multilevel regulation of Hif-1 signaling by TTP. Mol. Biol. Cell 23, 4129-41 (2012). 22918951 | 22918951 |
| 2660 | ZFP36 | ARP38303_P050 | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. Biomolecules. 5, 2035-55 (2015). 26343742 | 26343742 |
| 2661 | ZFP36 | ARP38303_P050 | Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy. Cell Mol Gastroenterol Hepatol. 11, 597-621 (2020). 32987153 | 32987153 |
| 2662 | ZFP91 | ARP36120_T100 | Xiao, C. et al. MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell 131, 146-59 (2007). 17923094 | 17923094 |
| 2663 | ZFR | ARP39227_P050 | Tucholska, M., Florentinus, A., Williams, D. & Marshall, J. G. The endogenous peptides of normal human serum extracted from the acetonitrile-insoluble precipitate using modified aqueous buffer with analysis by LC-ESI-Paul ion trap and Qq-TOF. J. Proteomics 73, 1254-69 (2010). 20211283 | 20211283 |
| 2664 | ZFX | ARP33498_P050 | Zha, W., Cao, L., Shen, Y. & Huang, M. Roles of Mir-144-ZFX pathway in growth regulation of non-small-cell lung cancer. PLoS One 8, e74175 (2013). 24066116 | 24066116 |
| 2665 | ZIC2 | ARP35821_P050 | Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2. Oncotarget. 6, 28257-68 (2015). 26318045 | 26318045 |
| 2666 | ZIC2 | ARP35821_P050 | ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells. J. Clin. Invest. 125, 3795-808 (2015). 26426078 | 26426078 |
| 2667 | ZIC2 | ARP35821_P050 | The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1. J Biol Chem. 293, 7982-7992 (2018). 29588366 | 29588366 |
| 2668 | ZIC5 | OAEB00858 | AR-regulated ZIC5 contributes to the aggressiveness of prostate cancer.Cell Death Discov39381September2022 | 36127329 |
| 2669 | ZIP4 | ARP44090_P050 | Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4. J. Biol. Chem. 290, 17796-805 (2015). 25971965 | 25971965 |
| 2670 | ZIP5 | ARP44143_P050 | Zinc Transport Differs in Rat Spermatogenic Cell Types and Is Affected by Treatment with Cyclophosphamide. Biol. Reprod. 95, 22 (2016). 27281708 | 27281708 |
| 2671 | ZNF142 | ARP38554_P050 | AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic. PLoS ONE. 10, e0128013 (2015). 26010094 | 26010094 |
| 2672 | ZNF179 | ARP34128_P050 | Goonetilleke, U. R. et al. Death is associated with complement C3 depletion in cerebrospinal fluid of patients with pneumococcal meningitis. MBio 3, (2012). 22415003 | 22415003 |
| 2673 | ZNF230 | ARP34554_P050 | Liu, Y. et al. A new mutant transcript generated in Znf230 exon 2 knockout mice reveals a potential exon structure in the targeting vector sequence. Acta Biochim. Biophys. Sin. (Shanghai). 45, 123-8 (2013). 23196134 | 23196134 |
| 2674 | ZNF294 | ARP43201_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2675 | ZNF295 | ARP32731_P050 | Spellman, C., Ahmed, M. M., Dubach, D. & Gardiner, K. J. Expression of trisomic proteins in Down syndrome model systems. Gene 512, 219-225 (2013). 23103828 | 23103828 |
| 2676 | ZNF307 | ARP39385_T100 | ZNF307 (Zinc Finger Protein 307) Acts as a Negative Regulator of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension. 69, 615-624 (2017). 28223477 | 28223477 |
| 2677 | ZNF318 | OAAB00158 | Rad52 mediates class-switch DNA recombination to IgD. Nat Commun 2022 1 13 980 35190531 | 35190531 |
| 2678 | ZNF384 | OACA04063 | ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activities.FEBS Lett2151-216159316August2019 | 31234226 |
| 2679 | ZNF580 | ARP39236_P050 | Hoffmann, C. J. et al. Suppression of zinc finger protein 580 by high oxLDL/LDL-ratios is followed by enhanced expression of endothelial IL-8. Atherosclerosis 216, 103-8 (2011). 21310414 | 21310414 |
| 2680 | ZNF580 | ARP39236_P050 | ZNF580 - a brake on Interleukin-6. J Inflamm (Lond). 15, 20 (2018). 30386182 | 30386182 |
| 2681 | ZNF645 | ARP36191_P050 | Bai, G. et al. Promoter demethylation mediates the expression of ZNF645, a novel cancer/testis gene. BMB Rep. 43, 400-6 (2010). 20587329 | 20587329 |
| 2682 | ZNF645 | ARP36191_P050 | Liu, Y.-Q. et al. Human RING finger protein ZNF645 is a novel testis-specific E3 ubiquitin ligase. Asian J. Androl. 12, 658-66 (2010). 20657603 | 20657603 |
| 2683 | ZP3 | ARP35855_T100 | Törmälä, R.-M. et al. Zona pellucida components are present in human fetal ovary before follicle formation. Mol. Cell. Endocrinol. 289, 10-5 (2008). 18502569 | 18502569 |
| 2684 | ZP3 | ARP35855_T100 | Morphometric characteristics of preantral and antral follicles and expression of factors involved in folliculogenesis in ovaries of adult baboons (Papio anubis). 26945754 | 26945754 |
| 2685 | ZPLD1 | ARP53315_P050 | Spontaneous mutations of the Zpld1 gene in mice cause semicircular canal dysfunction but do not impair gravity receptor or hearing functions. Sci Rep. 9, 12430 (2019). 31455802 | 31455802 |
| 2686 | ZRANB2 | ARP37747_T100 | Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections. J. Biol. Chem. 291, 4019-34 (2016). 26740623 | 26740623 |
| 2687 | ZSCAN5D | ARP47809_P050 | ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression. Oncotarget. 7, 72571-72592 (2016). 27732952 | 27732952 |
| 2688 | ZYX | ARP34387_T100 | Moody, J. D. et al. A zyxin head-tail interaction regulates zyxin-VASP complex formation. Biochem. Biophys. Res. Commun. 378, 625-8 (2009). 19061869 | 19061869 |
| 2689 | | OKEH02585 | Effect of T3 Spinal Contusion Injury on Upper Urinary Tract Function. Neurotrauma Rep 2022 1 3 190-198 35558732 | 35558732 |
| 2690 | | OKEH02527 | Intramuscular hyaluronic acid expression following repetitive power training induced nonfunctional overreaching. Appl Physiol Nutr Metab 2021 12 46 1563-1566 34437821 | 34437821 |
| 2691 | | OKEH02594 | Nanoparticle-Mediated Delivery of Emodin via Colonic Irrigation Attenuates Renal Injury in 5/6 Nephrectomized Rats. Front Pharmacol 2021 NULL 11 606227 33551808 | 33551808 |
| 2692 | | OKEH02559 | Purification of Lumbricus terrestris erythrocruorin (LtEc) with anion exchange chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2020 NULL 1150 122162 32505113 | 32505113 |
| 2693 | | OAMA00655 | Defining the specificity of recombinant human erythropoietin confirmation in equine samples by liquid chromatography-tandem mass spectrometry.Drug Test Anal676-689144April2022 | 34898016 |
| 2694 | | OAMA02979 | Long tail fibres of the novel broad-host-range T-even bacteriophage S16 specifically recognize Salmonella OmpC.Mol Microbiol818-34874February2013 | 23289425 |
| 2695 | | OKEH02566 | Melatonin Type 2 Receptor Activation Regulates Blue Light Exposure-Induced Mouse Corneal Epithelial Damage by Modulating Impaired Autophagy and Apoptosis.Int J Mol SciNULL2319September2022 | 36232639 |
| 2696 | | OKEH02566 | Effects of dim artificial light at night on locomotor activity, cardiovascular physiology, and circadian clock genes in a diurnal songbird.Environ Pollut117036282NULLAugust2021 | 33838441 |
| 2697 | | OKEH02568 | Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis.Ann Clin Transl Neurol786-79496June2022 | 35393764 |
